Steven Salzberg
stevensalzberg.bsky.social
Steven Salzberg
@stevensalzberg.bsky.social

Bloomberg Distinguished Professor of BME, CS, and Biostats at Johns Hopkins Univ., tennis player, @StevenSalzberg1 on Twitter, lab: salzberg-lab.org, Substack blog: stevensalzberg.substack.com

Steven Lloyd Salzberg is an American computational biologist and computer scientist who is a Bloomberg Distinguished Professor of Biomedical Engineering, Computer Science, and Biostatistics at Johns Hopkins University, where he is also Director of the Center for Computational Biology. .. more

Biology 74%
Agriculture 8%

great thread on Jim Watson from @jeremymberg.bsky.social, an insightful perspective
Bluetorial-Jim Watson

I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions.

What follows is my personal perspective.

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a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com

Reposted by Steven L. Salzberg

Bluetorial-Jim Watson

I met Jim Watson a few times but did not know him well. However, I was greatly influenced by his book “The Double Helix”. He was a complicated human being with some very, very bad features, but some good contributions.

What follows is my personal perspective.

1/41
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com

Reposted by Steven L. Salzberg

Our soon-to-be Surgeon General has some unscientific views. I have some thoughts about that... open.substack.com/pub/stevensa...
Dis-Functional Medicine in the Surgeon General's office
What the heck is Functional Medicine anyway?
open.substack.com

In @elife.bsky.social, our OpenSpliceAI paper, led by @kuanhaochao.bsky.social, is now 'official' though it's been online since July. If you want to enjoy the reviewers' comments and our responses, check it out at: doi.org/10.7554/eLif...
OpenSpliceAI provides an efficient modular implementation of SpliceAI enabling easy retraining across nonhuman species
OpenSpliceAI is an open, retrainable framework for splice site prediction that enables rapid, memory-efficient, cross-species analyses at scale with accuracy comparable to SpliceAI.
doi.org

My former mentor, colleague, and friend Hamilton Smith passed away this week. He was a giant in science, a Nobel Laureate, but also one of the nicest people you could ever meet. He will be missed by many. www.jcvi.org/media-center...
Remembering Hamilton O. Smith
Hamilton O. Smith August 31, 1931 – October 25, 2025 It is with profound sorrow that we announce the loss of Hamilton O. Smith, M.D., a...
www.jcvi.org

Wow indeed. This is a disaster for U.S. science in so many ways. We're losing the future.
Wow. Harvard nuking its PhD programs

- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero
Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...
www.thecrimson.com
Wow. Harvard nuking its PhD programs

- Science PhD admissions reduced by more than 75%
- Arts & Humanities reduced by about 60%
- Social Sciences by 50–70%
- History by 60%
- Biology by 75%
- The German department will lose all PhD seats
- Sociology from six PhD students to zero
Harvard FAS Cuts Ph.D. Seats By More Than Half Across Next Two Admissions Cycles | News | The Harvard Crimson
The Faculty of Arts and Sciences slashed the number of Ph.D. student admissions slots for the Science division by more than 75 percent and for the Arts & Humanities division by about 60 percent for th...
www.thecrimson.com

Reposted by Steven L. Salzberg

If you're anywhere near @cornelluniversity.bsky.social this Saturday, Oct 18, don't miss #Insectapalooza, the annual one-day insect festival! It's organized by @cornellcals.bsky.social Dept of Entomology cals.cornell.edu/entomology/r...
Insectapalooza
Come see the bizarre, bad, and beneficial of the insect world.2025 date will be Saturday, October 18th from 9am to 3pm. Stocking Hall.
cals.cornell.edu

actually it reminds me more of finding 1000s of human contaminants annotated as proteins within draft bacterial genomes in GenBank, which we published in 2018 (and @aphillippy.bsky.social knows this work): pubmed.ncbi.nlm.nih.gov/31064768/
Human contamination in bacterial genomes has created thousands of spurious proteins - PubMed
Contaminant sequences that appear in published genomes can cause numerous problems for downstream analyses, particularly for evolutionary studies and metagenomics projects. Our large-scale scan of com...
pubmed.ncbi.nlm.nih.gov

Reposted by Steven L. Salzberg

my co-author pointed out that our new Perspective piece in Cancer Research has 4 generations of mentorship for the 4 authors: Chia - Nagarajan - Pop - Salzberg (youngest to oldest) ;) brnw.ch/21wWgEi
Challenges and Opportunities in Analyzing Cancer-Associated Microbiomes
Abstract. The study of cancer-associated microbiomes has gained significant attention in recent years, spurred by advances in high-throughput sequencing and metagenomic analysis. Microbiome research h...
brnw.ch