Romain Koszul
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rkoszul.bsky.social
Romain Koszul
@rkoszul.bsky.social
#3Dgenome, #3R, #chromatin, #synbio, #microbiome... Opinions are my own.
Reposted by Romain Koszul
We are hiring!
January 30, 2026 at 4:33 PM
Reposted by Romain Koszul
Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!
January 27, 2026 at 6:56 PM
Reposted by Romain Koszul
Bacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive.

Here we explore the conjugative capacity of these mysterious Genomic Islands.

www.biorxiv.org/content/10.6...
www.biorxiv.org
January 14, 2026 at 10:14 AM
It's quite funny that they felt they had to explain it 😅🤣🙄

www.nytimes.com/2026/01/10/w...
Machado Offered Trump Her Nobel, but Prize Institute Says It’s Not Allowed
www.nytimes.com
January 10, 2026 at 4:54 PM
Reposted by Romain Koszul
Last work of the lab showing that Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
January 8, 2026 at 8:40 PM
Reposted by Romain Koszul
Seeking expressions of interest from researchers abroad for a Canada Impact+ Research Chair ($1M/year × 8 + up to $6M CFI) in AI-enabled antibiotic discovery and/or AMR, phage & phage-based derivatives. Email me a short vision, CV, and 3–5 key papers. Deadline: March 10, 2026 (Intake 2: June 15).
January 7, 2026 at 1:19 AM
Reposted by Romain Koszul
#USA - Le gouvernement états-unien entend multiplier les sanctions contre des personnalités européennes, à l’image de l’ancien commissaire européen Thierry Breton, interdit de visa. Les magistrats qui ont condamné Marine Le Pen en mars dernier seraient menacés.
#AnticorVeille
Les magistrats ayant condamné Marine Le Pen dans le viseur de l’administration Trump - L'Humanité
Le gouvernement états-unien entend multiplier les sanctions individuelles contre des personnalités européennes, à l’image de l’ancien commissaire européen Thierry Breton,...
www.humanite.fr
January 5, 2026 at 10:03 AM
Reposted by Romain Koszul
RFK, Jr.–Backed Lyme Disease Conspiracy Theory May Be Probed under New Bill

www.scientificamerican.com/article/rfk-...

President Donald Trump is expected to sign a defense bill this week that orders an investigation into whether the U.S. military bioengineered Lyme disease
RFK, Jr.–Backed Lyme Disease Conspiracy Theory May Be Probed under New Bill
President Donald Trump is expected to sign a defense bill this week that orders an investigation into whether the U.S. military bioengineered Lyme disease
www.scientificamerican.com
December 16, 2025 at 7:09 PM
Reposted by Romain Koszul
🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
Reposted by Romain Koszul
#RejoignezLeCNRS 🫵 Les concours chercheurs CNRS 2026 ouvrent le 8/12 !
Envie de faire avancer la science au sein d’un des plus grands organismes de recherche ?
👉 carrieres.cnrs.fr/concours-...

#ConcoursChercheurs #Science #Recherche #Icicarecrute #recrutement
November 25, 2025 at 10:02 AM
Reposted by Romain Koszul
How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵

www.science.org/doi/10.1126/...
Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals
Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...
www.science.org
November 27, 2025 at 7:55 PM
Reposted by Romain Koszul
Take this quiz to die instantly www.americansurveycenter.org/quiz/
Beyond the Ballot Quiz - The Survey Center on American Life
www.americansurveycenter.org
October 29, 2025 at 1:44 AM
Reposted by Romain Koszul
#JobOffer

💼 Un poste susceptible d’être vacant de Professeur en stabilité des génomes devrait s’ouvrir pour la rentrée 2026 au sein de l’Institut Jacques Monod

➡️ Informations concernant ce poste et la procédure de candidature 🔗 www.ijm.fr/poste-de-pro...
October 28, 2025 at 1:41 PM
Reposted by Romain Koszul
Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
October 15, 2025 at 4:17 PM
Reposted by Romain Koszul
Entretien pour Brut sur la vie Miroir, l'ingénierie génétique et l'éthique de ces recherches: www.brut.media/fr/videos/sc...
Manipulations génétiques, virus créés par l’IA, bactéries miroirs : quelles limites à la recherche scientifique ?
Elles pourraient aider à lutter contre les cancers… mais aussi détruire toute trace de vie sur Terre ! Ce sont les bactéries miroirs. En avez-vous déjà entendu parler ? Et la vie miroir, ça vous dit q...
www.brut.media
October 11, 2025 at 1:30 PM
Reposted by Romain Koszul
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...
October 9, 2025 at 2:06 PM
Reposted by Romain Koszul
How do SMC complexes load onto DNA to get ready for loop extrusion?

@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️.

Check out the new paper: www.cell.com/molecular-ce...
October 9, 2025 at 2:43 PM
Reposted by Romain Koszul
Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...
Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA
Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...
forum.image.sc
October 7, 2025 at 12:39 PM
Reposted by Romain Koszul
Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
October 3, 2025 at 4:06 PM
Reposted by Romain Koszul
📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...
Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle
The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...
www.biorxiv.org
September 25, 2025 at 7:12 AM
Reposted by Romain Koszul
What’s more astonishing: 1) that the president clearly believes, and repeatedly suggests, that asylum seekers are people from mental asylums, or 2) that no journalist has ever challenged him on this and no mainstream media outlets have done any deep dives on this story?
September 20, 2025 at 7:11 PM
New paper!
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC
September 19, 2025 at 12:49 PM
Reposted by Romain Koszul
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...
Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution
Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...
www.biorxiv.org
September 16, 2025 at 6:42 PM
Reposted by Romain Koszul
www.cell.com/cell/abstrac...

A host organelle (in sea slugs) integrates stolen chloroplasts for animal photosynthesis
A host organelle integrates stolen chloroplasts for animal photosynthesis
Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.
www.cell.com
September 17, 2025 at 5:04 PM