Gilles FISCHER
gillesfischer.bsky.social
Gilles FISCHER
@gillesfischer.bsky.social
Evolution, Genomics, Yeast
Reposted by Gilles FISCHER
📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️

“The rules of the game: biophysical & molecular principles in cellular evolution”

Apply by March 1st!
Please repost to help spread the word!

meetings.embo.org/event/26-cel...
#EMBORulesOfTheGame @gimmfoundation.bsky.social
The rules of the game: biophysical & molecular principles in cellular evolution
Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…
meetings.embo.org
December 18, 2025 at 3:48 PM
Reposted by Gilles FISCHER
Here is our first publication of 2026 which is the first article of a special issue that mark the journal 40 anniversary - happy new year to all the #yeast community
In this #Yeast review article, Jens Nielsen discusses how Saccharomyces cerevisiae has been used as both a model organism and a cell factory, shedding light on the molecular mechanisms of eukaryotic life but also boosting industrial biotechnology 💪💪💪

onlinelibrary.wiley.com/doi/10.1002/...
The Power of Yeast
Yeasts have been intimately connected with human civilization for millennia, originally used for fermentation in food and beverage production. This article explores the multifaceted roles of yeasts—p...
onlinelibrary.wiley.com
January 2, 2026 at 6:19 PM
Reposted by Gilles FISCHER
The new year has just started and we are happy to share the news that the new issue of #Yeast (Volume 42, Number 12, December 2025) is finally out!!! 😀😀😀

This issue includes two research articles and two reviews.

You can browse it at this link:

onlinelibrary.wiley.com/toc/10970061...
Happy 40th birthday Yeast: Yeast: Vol 42, No 12
Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.
onlinelibrary.wiley.com
January 5, 2026 at 2:47 PM
Reposted by Gilles FISCHER
Extinction rarely departs with drama, it slips out the back door while we’re still debating the guest list. These records are made official on the Red List. "Conservation failures are often recognised only once they can no longer be reversed."
via @mongabay.com: news.mongabay.com/short-articl...
December 29, 2025 at 3:18 AM
share.google
December 25, 2025 at 10:04 AM
Reposted by Gilles FISCHER
As many of us 🎁 things up for the year, make sure all your ℹ️'s are dotted- and all your #yeast emojis are downloaded! If you haven't yet, make sure to add the emojyeast collection to all your 📱💻🖥️⌚️

mayaschuldiner.wixsite.com/schuldinerla...

Thanks to the amazing Schuldiner lab for these!
December 12, 2025 at 11:20 PM
Reposted by Gilles FISCHER
New paper out: An archaeal genetic code with all TAG codons as pyrrolysine: www.science.org/doi/10.1126/...
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 23, 2025 at 7:22 PM
Reposted by Gilles FISCHER
When colonizing a new habitat, organisms adapt to maximize their reproductive success via #LifeHistory #evolution. @ecoevodevolab.bsky.social @cbank.bsky.social show that life history evolution facilitates niche diversification across a range of theoretical models @plosbiology.org 🧪 plos.io/4p7YT0a
November 13, 2025 at 10:02 AM
Reposted by Gilles FISCHER
In the latest #Yeast research article, Miguel A. Rocha, Gowda Bhavani and Jacob Fleischmann investigate the role of exonuclease-resistant ribosomal RNAs in Saccharomyces cerevisiae, their relationship with nutritional status and the TOR signalling pathway.

onlinelibrary.wiley.com/doi/10.1002/...
18S and 25S Exonuclease Resistant Ribosomal RNA Molecules Are Produced by 5′‐End Modification During TOR Inhibition.
Saccharomyces cerevisiae produces exonuclease-resistant rRNA molecules upon TOR inhibition. This phenomenon occurs when cells enter the diauxic phase, upon addition of rapamycin to the culture, or wh...
onlinelibrary.wiley.com
November 10, 2025 at 2:10 PM
Reposted by Gilles FISCHER
Nouvelle vidéo 🎉

Pourquoi le prix Nobel de physique 2024 concernait l'I.A. ? Comment sont nés les réseaux de neurones ? Quel est le lien avec les champs quantiques ?

Toutes ces réponses en 13 minutes ⤵️
youtu.be/2kbAId70b_I
La Physique de l'I.A.
YouTube video by ScienceClic
youtu.be
November 6, 2025 at 11:55 AM
Reposted by Gilles FISCHER
Independently evolved supergenes control colony social organization and queen reproductive strategies in several ant lineages. Sigeman et al. uncover a novel 9 Mb supergene controlling queen size and social organization in Myrmica ruginodis.

🔗 doi.org/10.1093/molbev/msaf255

#evobio #molbio #ants
November 5, 2025 at 11:24 AM
Reposted by Gilles FISCHER
The new issue of #Yeast of 2025 (Volume 42, Issue 11, November 2025) is out! It includes papers about new yeast genomes, the biodiversity of yeasts in dough, polyphosphate accumulation and even a new #FantasticYeasts species 😃

You can browse it at this link:

onlinelibrary.wiley.com/toc/10970061...
Happy 40th birthday Yeast: Yeast: Vol 42, No 11
Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.
onlinelibrary.wiley.com
November 5, 2025 at 3:59 PM
Reposted by Gilles FISCHER
Evolutionary responses to increased opportunity for sexual selection in yeast https://www.biorxiv.org/content/10.1101/2025.11.03.686343v1
November 5, 2025 at 4:31 AM
Reposted by Gilles FISCHER
If you have a loved one who's been "doing their own research" on TikTok (or, really, anywhere) about whether the Earth is round, you could try showing them this article instead. ⚛️🧪🔭 physicsworld.com/a/fighting-f...
Fighting flat-Earth theory – Physics World
Rachel Brazil explores ways in which the physics community can best combat unscientific thinking, such as the belief the Earth is flat
physicsworld.com
October 31, 2025 at 2:22 PM
Reposted by Gilles FISCHER
Big congratulations to Dilanaz Arisan (@rquatrini.bsky.social 's lab) and Pablo Quintrel (@fcocubillosr.bsky.social 's lab) for winning the best posters awards sponsored by the #Yeast journal at the @smbe-chile2025.bsky.social conference in Puerto Varas 🎉🎉🎉
October 13, 2025 at 9:06 AM
Reposted by Gilles FISCHER
The special issue will be guest-edited by @pjboynton.bsky.social (Wheaton College
Massachusetts, USA) and Pei-Yun Jenny Wu (CNRS
Bordeaux, France).

You can find more information on the accepted topics and submission instructions by using the QR code below:
September 8, 2025 at 5:26 PM
Reposted by Gilles FISCHER
New #Yeast paper out from the series #FantasticYeasts!!! @hittingerlab.bsky.social , Dana Opulente & team describe a novel species, Lachancea rosae, isolated from the wild rose Rosa californica 🌹

onlinelibrary.wiley.com/doi/10.1002/...
Taxogenomic Analysis of a Novel Yeast Species, Lachancea rosae Sp. Nov. F.A., Isolated From the Wild Rose Rosa californica
The discovery, description, and taxogenomic analysis of a novel species of Lachancea revealed correlations between gene content and carbon and nitrogen physiological assays.
onlinelibrary.wiley.com
September 2, 2025 at 2:34 PM
Reposted by Gilles FISCHER
Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution https://www.biorxiv.org/content/10.1101/2025.09.12.675800v1
September 16, 2025 at 5:33 PM
New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...
Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution
Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...
www.biorxiv.org
September 16, 2025 at 6:42 PM
Reposted by Gilles FISCHER
Cool application of microbiome in food science

Using metagenomics on Colombian cacao, they mapped how microbes influence chocolate flavors. Then they built a defined microbial consortium that replicates premium chocolate flavors -- validated by trained tasters!

www.nature.com/articles/s41...
A defined microbial community reproduces attributes of fine flavour chocolate fermentation - Nature Microbiology
An in-depth microbiological and metagenomic analysis of Colombian farm and fermentation facilities resulted in the design of a defined microbial community that can reproduce the flavour of fine chocol...
www.nature.com
August 19, 2025 at 8:07 PM
Reposted by Gilles FISCHER
The Yeast2025 meeting in Paris is over, and was so much fun. It was exciting to see a room full of yeast biologists, with more than 500 people. It was also great to be part of the dream team of organizers, led by @gillesfischer.bsky.social
July 27, 2025 at 1:52 PM
Reposted by Gilles FISCHER
At #yeast2025 and love the 90s hip hop style of the logo!
July 21, 2025 at 8:27 AM