Molecular Biology and Evolution
@molbioevol.bsky.social
MBE publishes fresh insights into the patterns and processes that impact the evolution of life at molecular levels.
🔗 academic.oup.com/mbe
🏠 @official-smbe.bsky.social
🤝 @genomebiolevol.bsky.social
#evobio #molbio #science #biology #societyjournal
🔗 academic.oup.com/mbe
🏠 @official-smbe.bsky.social
🤝 @genomebiolevol.bsky.social
#evobio #molbio #science #biology #societyjournal
Pinned
The January cover of Molecular Biology and Evolution features the work of Stanek et al., who investigated chromosome-specific size expansion by focusing on the Drosophila "dot chromosome”.
🔗 doi.org/10.1093/molbev/msaf304
#evobio #molbio #drosophila
🔗 doi.org/10.1093/molbev/msaf304
#evobio #molbio #drosophila
De Filippo et al. investigated the evolution of recombination suppression in dung fungi, revealing multiple, likely independent evolutionary strata, associated with an extended diploid-like stage in Schizothecium fungi.
🔗 doi.org/10.1093/molbev/msaf325
#evobio #molbio #fungi
🔗 doi.org/10.1093/molbev/msaf325
#evobio #molbio #fungi
Stepwise recombination suppression around the mating-type locus associated with a diploid-like life cycle in Schizothecium fungi
Abstract. Recombination suppression often evolves around sex-determining loci and extends stepwise, resulting in adjacent regions with different levels of
doi.org
January 15, 2026 at 3:20 PM
De Filippo et al. investigated the evolution of recombination suppression in dung fungi, revealing multiple, likely independent evolutionary strata, associated with an extended diploid-like stage in Schizothecium fungi.
🔗 doi.org/10.1093/molbev/msaf325
#evobio #molbio #fungi
🔗 doi.org/10.1093/molbev/msaf325
#evobio #molbio #fungi
From Nanyang Technological University, in Singapore, Hie Lim Kim brings her expertise on population genomics, environmental genomics, and human evolution to the MBE editorial board.
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January 14, 2026 at 5:32 PM
From Nanyang Technological University, in Singapore, Hie Lim Kim brings her expertise on population genomics, environmental genomics, and human evolution to the MBE editorial board.
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Suhua Shi (Sun Yat-sen University, China), researcher on speciation, adaptive evolution, plants, population genetics, joins the MBE editorial board as an Associate Editor.
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January 14, 2026 at 5:18 PM
Suhua Shi (Sun Yat-sen University, China), researcher on speciation, adaptive evolution, plants, population genetics, joins the MBE editorial board as an Associate Editor.
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@phiferrixey.bsky.social Ward & @katyamack.bsky.social investigated wild-derived strains of house mice from different climates on standard and high-fat diets, showing the potential of alternative splicing for adaptation and plasticity.
🔗 doi.org/10.1093/molbev/msaf332
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf332
#evobio #molbio
Alternative splicing contributes to plasticity and regulatory divergence in locally adapted house mice from the Americas
Abstract. Alternative splicing is a major driver of transcriptome and proteome variation, but the role of alternative splicing in regulatory evolution is o
doi.org
January 14, 2026 at 1:48 PM
@phiferrixey.bsky.social Ward & @katyamack.bsky.social investigated wild-derived strains of house mice from different climates on standard and high-fat diets, showing the potential of alternative splicing for adaptation and plasticity.
🔗 doi.org/10.1093/molbev/msaf332
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf332
#evobio #molbio
Chrudinová, @emrahaltindis.bsky.social et al. used >1000 insulin and insulin-like growth factor sequences from vertebrates, invertebrates, and viruses to uncover the evolution of this essential metabolic and developmental system.
🔗 doi.org/10.1093/molbev/msaf319
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf319
#evobio #molbio
Evolution of Insulin, Insulin-like Growth Factors, and Their Cognate Receptors in Vertebrates, Invertebrates, and Viruses
Abstract. The insulin and insulin-like growth factor (IGF) system regulates essential biological functions such as growth, metabolism, and development. Whi
doi.org
January 14, 2026 at 1:41 PM
Chrudinová, @emrahaltindis.bsky.social et al. used >1000 insulin and insulin-like growth factor sequences from vertebrates, invertebrates, and viruses to uncover the evolution of this essential metabolic and developmental system.
🔗 doi.org/10.1093/molbev/msaf319
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf319
#evobio #molbio
MBE welcomes Li Yu, Professor at Yunnan University (China), as a new Associate Editor specializing in mammal speciation, adaptive evolution, conservation, and metagenomics.
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January 14, 2026 at 12:36 PM
MBE welcomes Li Yu, Professor at Yunnan University (China), as a new Associate Editor specializing in mammal speciation, adaptive evolution, conservation, and metagenomics.
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Paschalia Kapli (@kaplipa.bsky.social), Research Leader at the Natural History Museum in the UK (@nhm-london.bsky.social), joins MBE as an Associate Editor, bringing in expertise on phylogenomics, phylogenetic discordance, and evolutionary radiations.
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January 13, 2026 at 3:04 PM
Paschalia Kapli (@kaplipa.bsky.social), Research Leader at the Natural History Museum in the UK (@nhm-london.bsky.social), joins MBE as an Associate Editor, bringing in expertise on phylogenomics, phylogenetic discordance, and evolutionary radiations.
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#societyjournal
Yongfeng Zhou, Professor at the Agricultural Genomes Institute at Shenzhen, China, is one of the new members of MBE's editorial board. He brings in his experience on plant domestication, structural variation, climate adaptation, and transposable elements.
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January 13, 2026 at 11:49 AM
Yongfeng Zhou, Professor at the Agricultural Genomes Institute at Shenzhen, China, is one of the new members of MBE's editorial board. He brings in his experience on plant domestication, structural variation, climate adaptation, and transposable elements.
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MBE welcomes Yichen (Serena) Dai (Fudan University, China) to its editorial board, who brings strong expertise in animal evolution, evo-devo, comparative genomics, and vertebrate evolution.
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January 13, 2026 at 10:03 AM
MBE welcomes Yichen (Serena) Dai (Fudan University, China) to its editorial board, who brings strong expertise in animal evolution, evo-devo, comparative genomics, and vertebrate evolution.
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Reposted by Molecular Biology and Evolution
Venom evolution is highly specialised with alternative splicing surprisingly playing a key role in lacewings👇:
green lacewing venom system and the complex mechanisms underlying its evolution url: academic.oup.com/mbe/article/...
green lacewing venom system and the complex mechanisms underlying its evolution url: academic.oup.com/mbe/article/...
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January 9, 2026 at 10:54 PM
Venom evolution is highly specialised with alternative splicing surprisingly playing a key role in lacewings👇:
green lacewing venom system and the complex mechanisms underlying its evolution url: academic.oup.com/mbe/article/...
green lacewing venom system and the complex mechanisms underlying its evolution url: academic.oup.com/mbe/article/...
Shuhua Xu (Fudan University, China), with experience in human genetics/"omics" and computational biology, joins MBE as an Associate Editor.
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January 12, 2026 at 4:58 PM
Shuhua Xu (Fudan University, China), with experience in human genetics/"omics" and computational biology, joins MBE as an Associate Editor.
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Miguel Arenas of the University of Vigo (@uvigo.bsky.social, Spain) joins our board as an Associate Editor. He is a researcher with expertise in molecular evolution, protein evolution, virus evolution, and phylogenetics.
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January 12, 2026 at 3:05 PM
Miguel Arenas of the University of Vigo (@uvigo.bsky.social, Spain) joins our board as an Associate Editor. He is a researcher with expertise in molecular evolution, protein evolution, virus evolution, and phylogenetics.
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Tianqi Zhu of the Academy of Mathematics and Systems Science (China) joins our editorial board to lend her experience on computational biology, Bayesian analysis, molecular clock, and sex chromosome evolution.
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January 12, 2026 at 9:43 AM
Tianqi Zhu of the Academy of Mathematics and Systems Science (China) joins our editorial board to lend her experience on computational biology, Bayesian analysis, molecular clock, and sex chromosome evolution.
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Maria Anisimova (Zurich University of Applied Sciences, Switzerland) brings expertise on models and methods, ancestral sequence reconstruction, and tests for selection to the MBE editorial board.
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January 9, 2026 at 12:32 PM
Maria Anisimova (Zurich University of Applied Sciences, Switzerland) brings expertise on models and methods, ancestral sequence reconstruction, and tests for selection to the MBE editorial board.
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Karen Siu Ting (@telmatobita.bsky.social), from Queen's University Belfast in the UK (@qubelfastofficial.bsky.social) joins the MBE editorial board as an Associate Editor, bringing expertise on phylogenomics, metagenomics, conservation, amphibians, and reptiles.
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January 9, 2026 at 10:08 AM
Karen Siu Ting (@telmatobita.bsky.social), from Queen's University Belfast in the UK (@qubelfastofficial.bsky.social) joins the MBE editorial board as an Associate Editor, bringing expertise on phylogenomics, metagenomics, conservation, amphibians, and reptiles.
#societyjournal
#societyjournal
MBE is proud to welcome 11 new Associate Editors to its Editorial Board!
These researchers bring a wealth of experience across molecular and evolutionary sciences and will carry out a vital service to our SMBE community. We will be presenting them throughout the coming days.
#societyjournal
These researchers bring a wealth of experience across molecular and evolutionary sciences and will carry out a vital service to our SMBE community. We will be presenting them throughout the coming days.
#societyjournal
January 9, 2026 at 10:05 AM
MBE is proud to welcome 11 new Associate Editors to its Editorial Board!
These researchers bring a wealth of experience across molecular and evolutionary sciences and will carry out a vital service to our SMBE community. We will be presenting them throughout the coming days.
#societyjournal
These researchers bring a wealth of experience across molecular and evolutionary sciences and will carry out a vital service to our SMBE community. We will be presenting them throughout the coming days.
#societyjournal
@simonokholm.bsky.social et al. examine the skin cancer hypothesis for the evolution of dark skin in early humans, arguing that protective effects were likely selected to mitigate other UV-related risks, rather than skin cancer.
🔗 doi.org/10.1093/molbev/msaf306
#evobio #molbio #humanevolution
🔗 doi.org/10.1093/molbev/msaf306
#evobio #molbio #humanevolution
January 9, 2026 at 9:07 AM
@simonokholm.bsky.social et al. examine the skin cancer hypothesis for the evolution of dark skin in early humans, arguing that protective effects were likely selected to mitigate other UV-related risks, rather than skin cancer.
🔗 doi.org/10.1093/molbev/msaf306
#evobio #molbio #humanevolution
🔗 doi.org/10.1093/molbev/msaf306
#evobio #molbio #humanevolution
Li, Huang & Li show that Asgard primases fall into two major groups, the Heimdall and Loki groups, which are phylogenetically and structurally more closely related to eukaryotic primases and to primases from non-Asgard archaea, respectively.
🔗 doi.org/10.1093/molbev/msaf330
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf330
#evobio #molbio
Phylogenetic and functional characterization of Asgard primases
Abstract. Eukarya resemble Archaea in DNA replication. Analysis of the DNA replication machinery of Asgard archaea may provide a valuable test of the hypot
doi.org
January 7, 2026 at 2:52 PM
Li, Huang & Li show that Asgard primases fall into two major groups, the Heimdall and Loki groups, which are phylogenetically and structurally more closely related to eukaryotic primases and to primases from non-Asgard archaea, respectively.
🔗 doi.org/10.1093/molbev/msaf330
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf330
#evobio #molbio
Shi et al. investigate the genomic architecture of distyly in Cordia subcordata; the candidate S-locus contained 12 genes, including CsGA2ox6, exclusively expressed in S-morph. Functional assays support this gene's role in heterostyly.
🔗 doi.org/10.1093/molbev/msaf322
#evobio #molbio #PlantSky
🔗 doi.org/10.1093/molbev/msaf322
#evobio #molbio #PlantSky
January 7, 2026 at 1:32 PM
Shi et al. investigate the genomic architecture of distyly in Cordia subcordata; the candidate S-locus contained 12 genes, including CsGA2ox6, exclusively expressed in S-morph. Functional assays support this gene's role in heterostyly.
🔗 doi.org/10.1093/molbev/msaf322
#evobio #molbio #PlantSky
🔗 doi.org/10.1093/molbev/msaf322
#evobio #molbio #PlantSky
Reposted by Molecular Biology and Evolution
My first paper on cancer an evolution i out in Molecular Biology and Evolution, @molbioevol.bsky.social. We retest the skin cancer hypothesis for dark skin evolution in ancestral humans, using migration-related mismatch and find acute UV-related risks likely drove selection doi.org/10.1093/molb...
Validate User
doi.org
January 7, 2026 at 10:05 AM
My first paper on cancer an evolution i out in Molecular Biology and Evolution, @molbioevol.bsky.social. We retest the skin cancer hypothesis for dark skin evolution in ancestral humans, using migration-related mismatch and find acute UV-related risks likely drove selection doi.org/10.1093/molb...
Tang et al. analyze genome data from 11 Xisima Cemetery individuals (China's Central Plain), demonstrating that social stratification occurred without corresponding genetic distinction, supporting decoupling of social hierarchy from genetics.
🔗 doi.org/10.1093/molbev/msaf316
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf316
#evobio #molbio
January 7, 2026 at 9:05 AM
Tang et al. analyze genome data from 11 Xisima Cemetery individuals (China's Central Plain), demonstrating that social stratification occurred without corresponding genetic distinction, supporting decoupling of social hierarchy from genetics.
🔗 doi.org/10.1093/molbev/msaf316
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf316
#evobio #molbio
Thawornwattana, Rannala & @zihengyang.bsky.social use simulation to study the false positive rate of a Bayesian test of gene flow under the MSC with multiple influencing factors.
🔗 doi.org/10.1093/molbev/msaf327
#evobio #molbio #compbio
🔗 doi.org/10.1093/molbev/msaf327
#evobio #molbio #compbio
On the robustness of Bayesian inference of gene flow to intragenic recombination and natural selection
Abstract. The multispecies coalescent (MSC) model provides a framework for detecting gene flow using genomic data, including between sister species. Howeve
doi.org
January 5, 2026 at 3:21 PM
Thawornwattana, Rannala & @zihengyang.bsky.social use simulation to study the false positive rate of a Bayesian test of gene flow under the MSC with multiple influencing factors.
🔗 doi.org/10.1093/molbev/msaf327
#evobio #molbio #compbio
🔗 doi.org/10.1093/molbev/msaf327
#evobio #molbio #compbio
@mariusmaur.bsky.social et al. investigate the venom system in Neuroptera by integrating genomics, transcriptomics and functional assays, showing that their toxin arsenal is the result of a multitude of genomic and evolutionary mechanisms.
🔗 doi.org/10.1093/molbev/msaf326
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf326
#evobio #molbio
The green lacewing venom system and the complex mechanisms underlying its evolution
Abstract. Venom has independently evolved across many lineages, yet relatively few have been studied in detail, particularly among insects. Of these, Neuro
doi.org
January 5, 2026 at 3:16 PM
@mariusmaur.bsky.social et al. investigate the venom system in Neuroptera by integrating genomics, transcriptomics and functional assays, showing that their toxin arsenal is the result of a multitude of genomic and evolutionary mechanisms.
🔗 doi.org/10.1093/molbev/msaf326
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf326
#evobio #molbio
Reposted by Molecular Biology and Evolution
Congrats to all @genomicsed.bsky.social students and faculty who participated!!
The January cover of Molecular Biology and Evolution features the work of Stanek et al., who investigated chromosome-specific size expansion by focusing on the Drosophila "dot chromosome”.
🔗 doi.org/10.1093/molbev/msaf304
#evobio #molbio #drosophila
🔗 doi.org/10.1093/molbev/msaf304
#evobio #molbio #drosophila
January 5, 2026 at 11:12 AM
Congrats to all @genomicsed.bsky.social students and faculty who participated!!
Haller, Ralph & Messer present SLiM 5, a major extension of the SLiM simulation framework for simulating multiple chromosomes, enabling a heightened level of realism for full-genome simulations.
🔗 doi.org/10.1093/molbev/msaf313
#evobio #molbio #compbio
🔗 doi.org/10.1093/molbev/msaf313
#evobio #molbio #compbio
January 5, 2026 at 8:53 AM
Haller, Ralph & Messer present SLiM 5, a major extension of the SLiM simulation framework for simulating multiple chromosomes, enabling a heightened level of realism for full-genome simulations.
🔗 doi.org/10.1093/molbev/msaf313
#evobio #molbio #compbio
🔗 doi.org/10.1093/molbev/msaf313
#evobio #molbio #compbio