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molbioevol.bsky.social
Molecular Biology and Evolution
@molbioevol.bsky.social
1.2K followers 37 following 290 posts
MBE publishes fresh insights into the patterns and processes that impact the evolution of life at molecular levels.

🔗 academic.oup.com/mbe

🏠 @official-smbe.bsky.social

🤝 @genomebiolevol.bsky.social

#evobio #molbio #science #biology #societyjournal
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molbioevol.bsky.social
Molecular Biology and Evolution @molbioevol.bsky.social · 10d
The November cover of Molecular Biology and Evolution features the work of Povilus et al., who examined DNA methylation and genetic imprinting in water lily endosperm.

🔗 doi.org/10.1093/molbev/msaf271

#evobio #molbio #PlantSky #epigenetics
Molecular Biology and Evolution | November 2025 cover
molbioevol.bsky.social
Zhou et al. present SMTdb, a spatial meta-transcriptome database that provides insights into the abundance, distribution, and enriched tumor microenvironment regions of 1,218 microbiota in spatial tissue slices.

🔗 doi.org/10.1093/molbev/msaf263

#evobio #molbio #cancer
MBE | SMTdb: A Comprehensive Spatial Meta-Transcriptome Resource in Cancer
November 7, 2025 at 9:35 AM
Reposted by Molecular Biology and Evolution
ryangutenkunst.bsky.social
This year's competition features demographic history inference and sweep detection. It closes in 1 week, so there's still time to enter! ghist.bio
November 6, 2025 at 4:22 PM
molbioevol.bsky.social
Community competitions help benchmark approaches in computational biology. Struck et al. now present GHIST 2024 - The First Genomic History Inference Strategies Tournament, for the inference of evolutionary history from genome data.

🔗 doi.org/10.1093/molbev/msaf257

#evobio #molbio #compbio #popgen
MBE | GHIST 2024: The First Genomic History Inference Strategies Tournament
November 6, 2025 at 3:20 PM
molbioevol.bsky.social
Independently evolved supergenes control colony social organization and queen reproductive strategies in several ant lineages. Sigeman et al. uncover a novel 9 Mb supergene controlling queen size and social organization in Myrmica ruginodis.

🔗 doi.org/10.1093/molbev/msaf255

#evobio #molbio #ants
MBE | A Novel Supergene Controls Queen Size and Colony Social Organization in the Ant Myrmica ruginodis
November 5, 2025 at 11:24 AM
molbioevol.bsky.social
Calvelo et al. present a comprehensive analysis of spliced leader (SL) trans-splicing of mRNA using genomic/ transcriptomic data of 24 cestode and trematode species, identifying a main pattern of concerted evolution of SL-RNA loci in most flatworms.

🔗 doi.org/10.1093/molbev/msaf228

#evobio #molbio
Evolution of SL-RNA Genes and Their Splicing Targets in Parasitic Flatworms
Abstract. Spliced leader (SL) trans-splicing is a key step in the processing of many mRNAs in different eukaryotic lineages, including in parasitic flatwor
doi.org
November 4, 2025 at 11:27 AM
molbioevol.bsky.social
Gámbaro, @sdellicour.bsky.social et al. use simulations to evaluate an adjusted Bayes factor for discrete phylogeography that accounts for sampling bias, which lowers false positives and improves root inference.

🔗 doi.org/10.1093/molbev/msaf253

#evobio #molbio #phylogenetics
Navigating Sampling Bias in Discrete Phylogeographic Analysis: Assessing the Performance of an Adjusted Bayes Factor
Abstract. Bayesian phylogeographic inference is widely used in molecular epidemiological studies to reconstruct the dispersal history of pathogens. Discret
doi.org
November 4, 2025 at 11:15 AM
Reposted by Molecular Biology and Evolution
jlsteenwyk.bsky.social
NEW Publication🥳

Rapid #evolution is thought to be disadvantageous due to the accumulation of deleterious #mutations. We identify multiple lineages of rapidly evolving and stable #yeast that are many millions of years old

🔗: academic.oup.com/mbe/advance-...
November 3, 2025 at 6:29 PM
Reposted by Molecular Biology and Evolution
psb-vib.bsky.social
PAPER from @yvdp.bsky.social @viblifesciences.bsky.social
academic.oup.com/mbe/article/...
Resolving the Stasis-Dynamism Paradox: Genome Evolution in Tree Ferns
Abstract. The paradox of evolutionary stasis and dynamism—how morphologically static lineages persist through deep geological periods despite environmental
academic.oup.com
November 3, 2025 at 11:19 AM
molbioevol.bsky.social
Gower et al. present an extension to the stdpopsim framework, which enables simulation of various modes of selection, providing a resource for the popgen community to explore the interplay between selection and other evolutionary forces.

🔗 doi.org/10.1093/molbev/msaf236

#evobio #molbio #compbio
Accessible, Realistic Genome Simulation with Selection Using stdpopsim
Abstract. Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realis
doi.org
November 3, 2025 at 10:07 AM
Reposted by Molecular Biology and Evolution
jomcinerney.bsky.social
I've often wondered about what we should call organisms whose similarity might be due to acquired genetic material. It got a little complicated, but I made a stab at it here

Classifying Convergences in the Light of Horizontal Gene Transfer: Epaktovars and Xenotypes academic.oup.com/mbe/article/...
Classifying Convergences in the Light of Horizontal Gene Transfer: Epaktovars and Xenotypes
Abstract. The classification of living systems presents significant challenges due to the prevalence of gene transfer between genomes. Traditional taxonomi
academic.oup.com
October 30, 2025 at 11:33 AM
molbioevol.bsky.social
Fu et al. used comparative genomics to investigate the evolution of rock-inhabiting fungi. They reveal these fungi have compact, gene-dense genomes, and two genes under positive selection across multiple lineages.

🔗 doi.org/10.1093/molbev/msaf249

#evobio #molbio #fungi
MBE | Genomic Insights Into Convergent Evolution: Adaptation to Rocky Habitats in Rock-Inhabiting Fungi
October 31, 2025 at 12:24 PM
molbioevol.bsky.social
What factors shape viral protein evolution? Fuchs et al. estimate evolutionary rates of numerous herpesvirus proteins and residues, revealing short- and long-term evolutionary constraints.

🔗 doi.org/10.1093/molbev/msaf256

#evobio #molbio #virus
Functional and Structural Determinants of Long- and Short-Term Evolution of Herpesvirus Proteins
Abstract. Understanding the factors that shape viral protein evolution is a central question in evolutionary virology. However, these determinants are poor
doi.org
October 31, 2025 at 12:19 PM
molbioevol.bsky.social
Liu, Sun & Liu investigated the mutational landscape of yeast, finding striking similarities between yeast and human cancers with the same pathway deficiencies, highlighting conserved mechanisms.

🔗 doi.org/10.1093/molbev/msaf252

#evobio #molbio #cancer
Comprehensive Mutational Landscape of Yeast Mutator Strains Reveals the Genetic Basis of Mutational Signatures in Cancer
Abstract. Spontaneous mutation rates and spectra are influenced by an intricate interplay of processes including DNA replication, proofreading, and diverse
doi.org
October 31, 2025 at 12:13 PM
molbioevol.bsky.social
Carlos J. Pardo-De la Hoz et al. studied the evolutionary history of the cyanobacteria Nostoc, demonstrating that rapid radiations are major contributors to the complex speciation history of this group.

🔗 doi.org/10.1093/molbev/msaf244

#evobio #molbio #cyanobacteria
Rapid Radiations Outweigh Reticulations During the Evolution of a 750-Million-Year-Old Lineage of Cyanobacteria
Abstract. Species are a fundamental unit of biodiversity. Yet, the existence of clear species boundaries among bacteria has long been a subject of debate.
doi.org
October 31, 2025 at 12:08 PM
molbioevol.bsky.social
The November cover of Molecular Biology and Evolution features the work of Povilus et al., who examined DNA methylation and genetic imprinting in water lily endosperm.

🔗 doi.org/10.1093/molbev/msaf271

#evobio #molbio #PlantSky #epigenetics
Molecular Biology and Evolution | November 2025 cover
October 31, 2025 at 10:37 AM
Reposted by Molecular Biology and Evolution
janekay27.bsky.social
Thank you for this opportunity and I'm excited to learn and actively contribute to science communication as a writing fellow at @molbioevol.bsky.social and @genomebiolevol.bsky.social

Congrats to the other fellows @haorancai.bsky.social and Shady Kuster, looking forward to working together!
official-smbe.bsky.social Society for Molecular Biology and Evolution @official-smbe.bsky.social · 12d
We are excited to welcome our three new SMBE Fellows!

Ioanna Kotari, Shady Kuster, and Haoran Cai will join @molbioevol.bsky.social and @genomebiolevol.bsky.social as writing fellows.

Keep an eye on our next Highlight articles in MBE and GBE!

#society #scicomm #evobio #molbio #genome #evolution
SMBE Fellows Program | 2025 cohort Ioanna Kotari (University of Veterinary Medicine Vienna) Shady A. Kuster (Colorado State University) Haoran Cai (University of California, Los Angeles)
October 30, 2025 at 5:24 PM
Reposted by Molecular Biology and Evolution
haorancai.bsky.social
I'm thrilled to be selected and grateful to be able to contribute to our community @official-smbe.bsky.social

Looking forward to new connections and future initiatives! @official-smbe.bsky.social @molbioevol.bsky.social @genomebiolevol.bsky.social
official-smbe.bsky.social Society for Molecular Biology and Evolution @official-smbe.bsky.social · 12d
We are excited to welcome our three new SMBE Fellows!

Ioanna Kotari, Shady Kuster, and Haoran Cai will join @molbioevol.bsky.social and @genomebiolevol.bsky.social as writing fellows.

Keep an eye on our next Highlight articles in MBE and GBE!

#society #scicomm #evobio #molbio #genome #evolution
SMBE Fellows Program | 2025 cohort Ioanna Kotari (University of Veterinary Medicine Vienna) Shady A. Kuster (Colorado State University) Haoran Cai (University of California, Los Angeles)
October 30, 2025 at 12:22 AM
Reposted by Molecular Biology and Evolution
official-smbe.bsky.social
We are excited to welcome our three new SMBE Fellows!

Ioanna Kotari, Shady Kuster, and Haoran Cai will join @molbioevol.bsky.social and @genomebiolevol.bsky.social as writing fellows.

Keep an eye on our next Highlight articles in MBE and GBE!

#society #scicomm #evobio #molbio #genome #evolution
SMBE Fellows Program | 2025 cohort Ioanna Kotari (University of Veterinary Medicine Vienna) Shady A. Kuster (Colorado State University) Haoran Cai (University of California, Los Angeles)
October 29, 2025 at 5:55 PM
Reposted by Molecular Biology and Evolution
turbokraken.bsky.social
MBE. Always feels a bit like coming home.
October 29, 2025 at 7:17 AM
molbioevol.bsky.social
Our recent article on human-virus co-evolution following the rise of agriculture is the focus of this month's Highlight.

Highlight: 10,000 Years of Agriculture-driven Human Evolution Through the Lens of a Single Gene

🔗 doi.org/10.1093/molbev/msaf245

#evobio #molbio #humanevolution
MBE | Highlight: 10,000 Years of Agriculture-driven Human Evolution Through the Lens of a Single Gene
October 28, 2025 at 10:19 AM
molbioevol.bsky.social
@gadji-mahamat.bsky.social et al. integrated 7-year gap temporal RNA-Seq, WGS PoolSeq and functional analyses to uncover resistance escalation mechanisms in Anopheles funestus across Africa, highlighting novel candidate genes for marker development.

🔗 doi.org/10.1093/molbev/msaf251

#evobio #molbio
Genomic Drivers of Pyrethroid Resistance Escalation in the Malaria Vector Anopheles funestus Across Africa
Abstract. Aggravation of pyrethroid resistance threatens malaria control; yet, its molecular basis remains elusive. This study used a comprehensive multi-o
doi.org
October 28, 2025 at 10:06 AM
molbioevol.bsky.social
@farleykvdg.bsky.social et al. investigate the importance of translation-enabling RNA editing in ferns, suggesting an adaptive role, in contrast to the prevailing view of RNA editing as a neutral evolutionary process.

🔗 doi.org/10.1093/molbev/msaf241

#evobio #molbio #PlantSky
MBE | High Conservation of Translation-Enabling RNA Editing Sites in Hyper-editing Ferns Implies They Are Not Selectively Neutral
October 27, 2025 at 11:30 AM
molbioevol.bsky.social
Wei et al. present chromosome-scale genomes for three ecologically divergent ferns, demonstrating how regulated genomic dynamism enables adaptive diversification while sustaining morphological conservatism.

🔗 doi.org/10.1093/molbev/msaf247

#evobio #molbio #PlantSky
Resolving the Stasis-Dynamism Paradox: Genome Evolution in Tree Ferns
Abstract. The paradox of evolutionary stasis and dynamism—how morphologically static lineages persist through deep geological periods despite environmental
doi.org
October 27, 2025 at 11:20 AM
molbioevol.bsky.social
@cellevol.bsky.social @turbokraken.bsky.social et al. used comparative genomics and experimental biology to investigate the evolution of mitochondrial and plastid import mechanisms in land plants.

🔗 doi.org/10.1093/molbev/msaf240

#evobio #molbio #PlantSky
Evolutionary Refinement of Mitochondrial and Plastid Targeting Sequences Coincides with the Late Diversification of Land Plants
Abstract. Plastids and mitochondria are key to plant survival and adaptation. The evolutionary progress of land plants (embryophytes) witnessed gene and ge
doi.org
October 27, 2025 at 11:15 AM
Reposted by Molecular Biology and Evolution
gadji-mahamat.bsky.social
Exited to share with you our latest paper on
Genomic Drivers of Pyrethroid Resistance Escalation in the Malaria Vector Anopheles funestus Across Africa url: academic.oup.com/mbe/article/...
Genomic Drivers of Pyrethroid Resistance Escalation in the Malaria Vector Anopheles funestus Across Africa
Abstract. Aggravation of pyrethroid resistance threatens malaria control; yet, its molecular basis remains elusive. This study used a comprehensive multi-o
academic.oup.com
October 26, 2025 at 1:56 AM