Animalcules
@bacteriophile.bsky.social
Bacteria lover. Good, bad, or other wise. Beneficial, commensal, or pathogenic alike.
Authorized GMB (Genetically Modified Bacteria) scientist
Authorized GMB (Genetically Modified Bacteria) scientist
Reposted by Animalcules
Characterizing Cell-Free Transcription and Translation Dynamics with Nucleic Acid–Based Assays
doi.org/10.1021/acss...
doi.org/10.1021/acss...
Characterizing Cell-Free Transcription and Translation Dynamics with Nucleic Acid–Based Assays
Characterization of cell-free expression (CFE) systems must expand beyond single spectrophotometric measurements of a green fluorescent protein to provide meaningful metrics of system performance duri...
doi.org
December 26, 2025 at 10:37 PM
Characterizing Cell-Free Transcription and Translation Dynamics with Nucleic Acid–Based Assays
doi.org/10.1021/acss...
doi.org/10.1021/acss...
@laasya2.bsky.social @deepaagashe.bsky.social et al. quantified the growth cost of mistranslation rates and exposure to antibiotics in E. coli, finding that altered translation accuracy can shape adaptive outcomes.
🔗 doi.org/10.1093/molbev/msaf312
🖌️ Nishant Asawadekar
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf312
🖌️ Nishant Asawadekar
#evobio #molbio
December 20, 2025 at 8:27 AM
Reposted by Animalcules
Rolling-circle replication of extracellular DNA by prophage activation in bacterial biofilms ⭕🧬🦠
Biology is crazy and beautiful 🤯
www.biorxiv.org/content/10.6...
Biology is crazy and beautiful 🤯
www.biorxiv.org/content/10.6...
December 7, 2025 at 1:08 PM
Rolling-circle replication of extracellular DNA by prophage activation in bacterial biofilms ⭕🧬🦠
Biology is crazy and beautiful 🤯
www.biorxiv.org/content/10.6...
Biology is crazy and beautiful 🤯
www.biorxiv.org/content/10.6...
Reposted by Animalcules
Phage–bacteria dynamics: The tragedy of the commons at hyperspeed
#phage #phageky
www.cell.com/current-biol...
#phage #phageky
www.cell.com/current-biol...
Phage–bacteria dynamics: The tragedy of the commons at hyperspeed
A recent study found that apparently stable coexistence between a clinically important
pathogen, Pseudomonas aeruginosa, and its integrated prophages can break down, setting
off an evolutionary cycle ...
www.cell.com
December 7, 2025 at 2:46 PM
Phage–bacteria dynamics: The tragedy of the commons at hyperspeed
#phage #phageky
www.cell.com/current-biol...
#phage #phageky
www.cell.com/current-biol...
Reposted by Animalcules
Spx inhibits expression of the SwrA•DegU master flagellar activator in Bacillus subtilis
-in JBacteriol
journals.asm.org/doi/10.1128/...
-in JBacteriol
journals.asm.org/doi/10.1128/...
Spx inhibits expression of the SwrA•DegU master flagellar activator in Bacillus subtilis | Journal of Bacteriology
Bacterial flagella are elaborate machines that are inserted through the bacterial
cell envelope. The regulation of flagellar gene expression is organized in hierarchical
tiers that largely correlate w...
journals.asm.org
December 6, 2025 at 8:36 PM
Spx inhibits expression of the SwrA•DegU master flagellar activator in Bacillus subtilis
-in JBacteriol
journals.asm.org/doi/10.1128/...
-in JBacteriol
journals.asm.org/doi/10.1128/...
Pleased to share our recent article in PNAS - a collaboration with @jessicaandreani.bsky.social & Pablo Radicella, with important roles played by many members of each team.
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes www.pnas.org/doi/10.1073/...
A tripartite protein complex promotes DNA transport during natural transformation in Firmicutes | PNAS
Natural genetic transformation is a conserved mechanism of bacterial horizontal gene
transfer, which is directed entirely by the recipient cell and...
www.pnas.org
November 26, 2025 at 9:22 AM
Reposted by Animalcules
Accelerating science with AI
"By empowering researchers across all disciplines and institutions to accelerate science and engineering, AI could increase the productivity and impact of research, boost innovation, fuel economic growth, and improve people’s lives."
www.science.org/doi/10.1126/...
"By empowering researchers across all disciplines and institutions to accelerate science and engineering, AI could increase the productivity and impact of research, boost innovation, fuel economic growth, and improve people’s lives."
www.science.org/doi/10.1126/...
November 26, 2025 at 3:45 AM
Accelerating science with AI
"By empowering researchers across all disciplines and institutions to accelerate science and engineering, AI could increase the productivity and impact of research, boost innovation, fuel economic growth, and improve people’s lives."
www.science.org/doi/10.1126/...
"By empowering researchers across all disciplines and institutions to accelerate science and engineering, AI could increase the productivity and impact of research, boost innovation, fuel economic growth, and improve people’s lives."
www.science.org/doi/10.1126/...
ribosomologists (bacteria dept.) take note 👇
Evolutionary Flexibility of Ribosome Biogenesis in Bacteria | Molecular Biology and Evolution | Oxford Academic https://academic.oup.com/mbe/article/42/11/msaf288/8340222?login=false
November 25, 2025 at 11:06 AM
Reposted by Animalcules
High-throughput cultivation and isolation of environmental anaerobes using selectively permeable hydrogel capsules. academic.oup.com/ismecommun/a...
High-throughput cultivation and isolation of environmental anaerobes using selectively permeable hydrogel capsules
Abstract. Over the past two decades, metagenomics has greatly expanded our understanding of microbial phylogenetic and metabolic diversity. However, most m
academic.oup.com
November 25, 2025 at 8:56 AM
High-throughput cultivation and isolation of environmental anaerobes using selectively permeable hydrogel capsules. academic.oup.com/ismecommun/a...
Reposted by Animalcules
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
November 24, 2025 at 4:57 PM
#OpenCloning is a an Open Source alternative to SnapGene/Benchling that supports automation and integration with other software
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
✅ Free
🔓 Open Source
🧬 More cloning methods than SnapGene
🤖 Can be automated with python
👨🔬 Built by a researcher — for researchers!
👉 Check it out at opencloning.org
Reposted by Animalcules
Arbitrium systems control lysis/lysogeny through the regulation of small antirepressor proteins www.biorxiv.org/content/10.1...
November 25, 2025 at 5:59 AM
Arbitrium systems control lysis/lysogeny through the regulation of small antirepressor proteins www.biorxiv.org/content/10.1...
Reposted by Animalcules
Sang Yup Lee’s research is at another level.
November 16, 2025 at 1:11 PM
Sang Yup Lee’s research is at another level.
Reposted by Animalcules
Molecular Microbiology | Microbiology Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
#MicroSky
#MicroSky
Cyclic Di‐AMP Affects Cell Membrane Integrity of Streptococcus pneumoniae
When Streptococcus pneumoniae produces low amounts of the second messenger cyclic di-AMP (c-di-AMP), they do not survive in the presence of competence-stimulating peptide (CSP), which is used for tra...
onlinelibrary.wiley.com
November 24, 2025 at 8:02 PM
Molecular Microbiology | Microbiology Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
#MicroSky
#MicroSky
Molecular Microbiology | Microbiology Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
#MicroSky
#MicroSky
A Cas12a Toolbox for Rapid and Flexible Group B Streptococcus Genomic Editing and CRISPRi
We developed a resource set and protocols that allow researchers to quickly alter or silence genes in Group B Streptococcus. Using flexible plasmids and a drug-inducible Cas12a system, the approach e....
onlinelibrary.wiley.com
November 24, 2025 at 7:59 PM
Molecular Microbiology | Microbiology Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/...
#MicroSky
#MicroSky
Reposted by Animalcules
It's the season for being thankful - THANK A MICROBE returns! Here's the first of several student flyers appreciating the wonders of our microbial world!
November 23, 2025 at 11:31 PM
It's the season for being thankful - THANK A MICROBE returns! Here's the first of several student flyers appreciating the wonders of our microbial world!
Reposted by Animalcules
