Nature Microbiology
@natmicrobiol.nature.com
Nature Microbiology publishes the latest research and commentary in all areas of microbiology.
https://www.nature.com/nmicrobiol/
https://www.nature.com/nmicrobiol/
Pinned
Dive into our November issue featuring:
🪆nested archaeal symbioses
🌱microbiota driven drought responses in plants
🏗️ BAM complex in Bacteroidota
💨microbial fermentative growth in the gut
🍸hospital-specific phage therapy cocktail
and much more..!
www.nature.com/nmicrobiol/v...
🪆nested archaeal symbioses
🌱microbiota driven drought responses in plants
🏗️ BAM complex in Bacteroidota
💨microbial fermentative growth in the gut
🍸hospital-specific phage therapy cocktail
and much more..!
www.nature.com/nmicrobiol/v...
Reposted by Nature Microbiology
I'm thrilled to share our newest publication in @natmicrobiol.nature.com, led by Drs. @botanichole.bsky.social, Valéria Custódio, and David Gopaulchan: Precipitation legacy effects on #SoilMicrobiota facilitate adaptive drought responses in plants. 🌾 🧪 (thread)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants - Nature Microbiology
Metagenomes from prairie soils in Kansas, USA, show how historical exposure to water stress impacts soil microorganisms and subsequently drought responses in plants.
www.nature.com
November 10, 2025 at 4:45 PM
I'm thrilled to share our newest publication in @natmicrobiol.nature.com, led by Drs. @botanichole.bsky.social, Valéria Custódio, and David Gopaulchan: Precipitation legacy effects on #SoilMicrobiota facilitate adaptive drought responses in plants. 🌾 🧪 (thread)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nature Microbiology
Can we leverage bacterial competition for targeted replacement of harmful strains? Maybe! Our recent piece in @natmicrobiol.nature.com provides a theoretical framework and a set of experiments to show what it might take: www.nature.com/articles/s41...
Strain displacement in microbiomes via ecological competition - Nature Microbiology
Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.
www.nature.com
November 7, 2025 at 10:34 PM
Can we leverage bacterial competition for targeted replacement of harmful strains? Maybe! Our recent piece in @natmicrobiol.nature.com provides a theoretical framework and a set of experiments to show what it might take: www.nature.com/articles/s41...
Reposted by Nature Microbiology
The latest paper by @erikbakkeren.bsky.social and the Foster group shows a potential way to engineer the microbiome by replacing problem strains with beneficial ones
Find out more @natmicrobiol.nature.com:
www.nature.com/articles/s41...
Find out more @natmicrobiol.nature.com:
www.nature.com/articles/s41...
Strain displacement in microbiomes via ecological competition - Nature Microbiology
Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.
www.nature.com
November 10, 2025 at 10:40 AM
The latest paper by @erikbakkeren.bsky.social and the Foster group shows a potential way to engineer the microbiome by replacing problem strains with beneficial ones
Find out more @natmicrobiol.nature.com:
www.nature.com/articles/s41...
Find out more @natmicrobiol.nature.com:
www.nature.com/articles/s41...
#NewResearch
Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors
#microsky #IDsky
www.nature.com/articles/s41...
Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors
#microsky #IDsky
www.nature.com/articles/s41...
Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors - Nature Microbiology
The cryo-EM structure of the herpes simplex virus helicase–primase (HP) complex informs about the mechanism of action of HP inhibitors pritelivir and amenamevir, which are drugs of clinical relevance.
www.nature.com
November 7, 2025 at 11:20 AM
#NewResearch
Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors
#microsky #IDsky
www.nature.com/articles/s41...
Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors
#microsky #IDsky
www.nature.com/articles/s41...
#NewResearch
Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae
#microsky
www.nature.com/articles/s41...
Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae
#microsky
www.nature.com/articles/s41...
Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae - Nature Microbiology
In situ cryo-electron microscopy structures show the spatial arrangement of flagellin proteins and provide insight into mechanisms of assembly and rotation of the sheathed flagellum in Vibrio cholerae...
www.nature.com
November 7, 2025 at 11:20 AM
#NewResearch
Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae
#microsky
www.nature.com/articles/s41...
Structures of the sheathed flagellum reveal mechanisms of assembly and rotation in Vibrio cholerae
#microsky
www.nature.com/articles/s41...
#NewResearch
Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes
@rstepanauskas.bsky.social & co
#microsky
www.nature.com/articles/s41...
Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes
@rstepanauskas.bsky.social & co
#microsky
www.nature.com/articles/s41...
Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes - Nature Microbiology
Environmental micro-compartment genomics provides efficient and high-throughput single-particle DNA sequencing that captures overlooked members of microbial communities.
www.nature.com
November 7, 2025 at 11:19 AM
#NewResearch
Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes
@rstepanauskas.bsky.social & co
#microsky
www.nature.com/articles/s41...
Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes
@rstepanauskas.bsky.social & co
#microsky
www.nature.com/articles/s41...
#NewResearch
Genetic population structure of Haemophilus influenzae at local and global scales
#microsky #IDsky
@paulturnermicro.bsky.social & co
www.nature.com/articles/s41...
Genetic population structure of Haemophilus influenzae at local and global scales
#microsky #IDsky
@paulturnermicro.bsky.social & co
www.nature.com/articles/s41...
Genetic population structure of Haemophilus influenzae at local and global scales - Nature Microbiology
Large-scale sequencing and population genomic analyses reveal frequent transmission, a highly admixed global population structure and evidence of pervasive negative selection in Haemophilus influenzae...
www.nature.com
November 7, 2025 at 11:18 AM
#NewResearch
Genetic population structure of Haemophilus influenzae at local and global scales
#microsky #IDsky
@paulturnermicro.bsky.social & co
www.nature.com/articles/s41...
Genetic population structure of Haemophilus influenzae at local and global scales
#microsky #IDsky
@paulturnermicro.bsky.social & co
www.nature.com/articles/s41...
Reposted by Nature Microbiology
A great collaboration with Jukka Corander and colleagues, to define the population structure of this important global pathogen
A first step towards identifying candidate antigens for new improved vaccines...
@tropicalmedicine.ox.ac.uk @wellcometrust.bsky.social
www.nature.com/articles/s41...
A first step towards identifying candidate antigens for new improved vaccines...
@tropicalmedicine.ox.ac.uk @wellcometrust.bsky.social
www.nature.com/articles/s41...
Genetic population structure of Haemophilus influenzae at local and global scales - Nature Microbiology
Large-scale sequencing and population genomic analyses reveal frequent transmission, a highly admixed global population structure and evidence of pervasive negative selection in Haemophilus influenzae...
www.nature.com
November 1, 2025 at 10:16 AM
A great collaboration with Jukka Corander and colleagues, to define the population structure of this important global pathogen
A first step towards identifying candidate antigens for new improved vaccines...
@tropicalmedicine.ox.ac.uk @wellcometrust.bsky.social
www.nature.com/articles/s41...
A first step towards identifying candidate antigens for new improved vaccines...
@tropicalmedicine.ox.ac.uk @wellcometrust.bsky.social
www.nature.com/articles/s41...
#NewResearch
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B
#microsky
www.nature.com/articles/s41...
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B
#microsky
www.nature.com/articles/s41...
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B - Nature Microbiology
Cryo-EM structures of the stabilized prefusion conformation of the glycoprotein B ectodomain—the HSV-1 entry machine—identify a prefusion-specific neutralizing antibody and reveal how prefusion glycop...
www.nature.com
November 7, 2025 at 11:17 AM
#NewResearch
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B
#microsky
www.nature.com/articles/s41...
Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B
#microsky
www.nature.com/articles/s41...
Out now!
Taxonomic expansion and reorganization of Flaviviridae
@vasilakislab.bsky.social @grovearmada.bsky.social & co
#microsky
www.nature.com/articles/s41...
Taxonomic expansion and reorganization of Flaviviridae
@vasilakislab.bsky.social @grovearmada.bsky.social & co
#microsky
www.nature.com/articles/s41...
Taxonomic expansion and reorganization of Flaviviridae - Nature Microbiology
Analysis of RNA polymerase hallmark gene phylogenies supported by protein structure relationships of flaviviruses and ‘flavi-like’ viruses underpins the taxonomic expansion and reorganization of Flavi...
www.nature.com
November 7, 2025 at 11:15 AM
Out now!
Taxonomic expansion and reorganization of Flaviviridae
@vasilakislab.bsky.social @grovearmada.bsky.social & co
#microsky
www.nature.com/articles/s41...
Taxonomic expansion and reorganization of Flaviviridae
@vasilakislab.bsky.social @grovearmada.bsky.social & co
#microsky
www.nature.com/articles/s41...
#NewResearch
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation
@bgewurz.bsky.social
#microsky
www.nature.com/articles/s41...
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation
@bgewurz.bsky.social
#microsky
www.nature.com/articles/s41...
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation - Nature Microbiology
The human host factors LSD1, CoREST and ZNF217 are important in maintaining Epstein–Barr virus latency, and the depletion of these factors or inhibition of LSD1 can trigger Epstein–Barr virus reactiva...
www.nature.com
November 7, 2025 at 11:13 AM
#NewResearch
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation
@bgewurz.bsky.social
#microsky
www.nature.com/articles/s41...
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation
@bgewurz.bsky.social
#microsky
www.nature.com/articles/s41...
#NewResearch
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus - Nature Microbiology
Florfenicol amine hijacks intrinsic resistance in Mycobacterium abscessus, highlighting that antimicrobial resistance mechanisms can be harnessed for antibiotic activation.
www.nature.com
November 7, 2025 at 11:11 AM
#NewResearch
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Prodrug florfenicol amine is activated by intrinsic resistance to target Mycobacterium abscessus
#microsky #IDsky
www.nature.com/articles/s41...
Out now!
An updated evolutionary classification of CRISPR–Cas systems including rare variants
#microsky
www.nature.com/articles/s41...
An updated evolutionary classification of CRISPR–Cas systems including rare variants
#microsky
www.nature.com/articles/s41...
An updated evolutionary classification of CRISPR–Cas systems including rare variants - Nature Microbiology
An exploration of previously undescribed variants from the long tail of the CRISPR–Cas distribution.
www.nature.com
November 7, 2025 at 11:10 AM
Out now!
An updated evolutionary classification of CRISPR–Cas systems including rare variants
#microsky
www.nature.com/articles/s41...
An updated evolutionary classification of CRISPR–Cas systems including rare variants
#microsky
www.nature.com/articles/s41...
#NewResearch
Strain displacement in microbiomes via ecological competition
@erikbakkeren.bsky.social
#microsky
www.nature.com/articles/s41...
Strain displacement in microbiomes via ecological competition
@erikbakkeren.bsky.social
#microsky
www.nature.com/articles/s41...
Strain displacement in microbiomes via ecological competition - Nature Microbiology
Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.
www.nature.com
November 7, 2025 at 11:09 AM
#NewResearch
Strain displacement in microbiomes via ecological competition
@erikbakkeren.bsky.social
#microsky
www.nature.com/articles/s41...
Strain displacement in microbiomes via ecological competition
@erikbakkeren.bsky.social
#microsky
www.nature.com/articles/s41...
Reposted by Nature Microbiology
After 5 years of waiting, the new #CRISPR classification by Makarova et al. is out @natmicrobiol.nature.com www.nature.com/articles/s41...
An updated evolutionary classification of CRISPR–Cas systems including rare variants - Nature Microbiology
An exploration of previously undescribed variants from the long tail of the CRISPR–Cas distribution.
www.nature.com
November 6, 2025 at 1:49 PM
After 5 years of waiting, the new #CRISPR classification by Makarova et al. is out @natmicrobiol.nature.com www.nature.com/articles/s41...
Reposted by Nature Microbiology
🧬 Thrilled to share our latest paper in @natmicrobiol.nature.com 📄
A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think.
Our at-scale AI structure prediction gave a complementary perspective on viral evolution.
www.nature.com/articles/s41...
A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think.
Our at-scale AI structure prediction gave a complementary perspective on viral evolution.
www.nature.com/articles/s41...
Taxonomic expansion and reorganization of Flaviviridae - Nature Microbiology
Analysis of RNA polymerase hallmark gene phylogenies supported by protein structure relationships of flaviviruses and ‘flavi-like’ viruses underpins the taxonomic expansion and reorganization of Flavi...
www.nature.com
November 6, 2025 at 12:52 PM
🧬 Thrilled to share our latest paper in @natmicrobiol.nature.com 📄
A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think.
Our at-scale AI structure prediction gave a complementary perspective on viral evolution.
www.nature.com/articles/s41...
A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think.
Our at-scale AI structure prediction gave a complementary perspective on viral evolution.
www.nature.com/articles/s41...
Reposted by Nature Microbiology
🚀 New in @natmicrobiol.nature.com
EMCG — droplet-based single-particle genomics method 🧬⚠️Sequencing marine microbes one by one — in nL of seawater!
Ultra-high resolution — no culture, no bulk averaging. A new way to see the invisible 🫥 🌊 rdcu.be/eOsUF #protistsonsky @bigelowlab.bsky.social
EMCG — droplet-based single-particle genomics method 🧬⚠️Sequencing marine microbes one by one — in nL of seawater!
Ultra-high resolution — no culture, no bulk averaging. A new way to see the invisible 🫥 🌊 rdcu.be/eOsUF #protistsonsky @bigelowlab.bsky.social
Single-particle genomics uncovers abundant non-canonical marine viruses from nanolitre volumes
Nature Microbiology - Environmental micro-compartment genomics provides efficient and high-throughput single-particle DNA sequencing that captures overlooked members of microbial communities.
rdcu.be
November 5, 2025 at 8:34 PM
🚀 New in @natmicrobiol.nature.com
EMCG — droplet-based single-particle genomics method 🧬⚠️Sequencing marine microbes one by one — in nL of seawater!
Ultra-high resolution — no culture, no bulk averaging. A new way to see the invisible 🫥 🌊 rdcu.be/eOsUF #protistsonsky @bigelowlab.bsky.social
EMCG — droplet-based single-particle genomics method 🧬⚠️Sequencing marine microbes one by one — in nL of seawater!
Ultra-high resolution — no culture, no bulk averaging. A new way to see the invisible 🫥 🌊 rdcu.be/eOsUF #protistsonsky @bigelowlab.bsky.social
Reposted by Nature Microbiology
Hi everyone, a few years ago, we started a list of labs studying bacterial immunty for students, editors, conference organizers... (currently n=79).
Update time ! Send me a message to 1) add your lab or others 2) Correct info
docs.google.com/spreadsheets...
#Phagesky #Microsky
Update time ! Send me a message to 1) add your lab or others 2) Correct info
docs.google.com/spreadsheets...
#Phagesky #Microsky
Labs in bacterial immunity
docs.google.com
November 4, 2025 at 3:06 PM
Hi everyone, a few years ago, we started a list of labs studying bacterial immunty for students, editors, conference organizers... (currently n=79).
Update time ! Send me a message to 1) add your lab or others 2) Correct info
docs.google.com/spreadsheets...
#Phagesky #Microsky
Update time ! Send me a message to 1) add your lab or others 2) Correct info
docs.google.com/spreadsheets...
#Phagesky #Microsky
Reposted by Nature Microbiology
A previously uncharacterized microbial enzyme is responsible for the production of molecular hydrogen in the gut, which drives the growth of other bacteria and has implications for human health, according to a paper in Nature Microbiology. go.nature.com/4oKOveG #microbiome #medsky 🧪
November 5, 2025 at 2:08 PM
A previously uncharacterized microbial enzyme is responsible for the production of molecular hydrogen in the gut, which drives the growth of other bacteria and has implications for human health, according to a paper in Nature Microbiology. go.nature.com/4oKOveG #microbiome #medsky 🧪
#NewResearch
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor
#microsky
www.nature.com/articles/s41...
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor
#microsky
www.nature.com/articles/s41...
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor - Nature Microbiology
The HKU25 clade MERS-related coronaviruses with broad distribution are shown to use ACE2 as a functional receptor, revealing unexpected receptor plasticity and offering new insights into coronavirus e...
www.nature.com
November 5, 2025 at 3:44 PM
#NewResearch
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor
#microsky
www.nature.com/articles/s41...
HKU25 clade MERS-related coronaviruses use ACE2 as a functional receptor
#microsky
www.nature.com/articles/s41...
#NewResearch
HIV and antiretroviral therapies exert distinct influences across diverse gut microbiomes
#microsky
www.nature.com/articles/s41...
HIV and antiretroviral therapies exert distinct influences across diverse gut microbiomes
#microsky
www.nature.com/articles/s41...
Human immunodeficiency virus and antiretroviral therapies exert distinct influences across diverse gut microbiomes - Nature Microbiology
Metagenomic analysis of the gut microbiome of people with human immunodeficiency virus (HIV), from three distinct cohorts, revealed infection- and antiretroviral drug-linked alterations, which may con...
www.nature.com
November 5, 2025 at 3:43 PM
#NewResearch
HIV and antiretroviral therapies exert distinct influences across diverse gut microbiomes
#microsky
www.nature.com/articles/s41...
HIV and antiretroviral therapies exert distinct influences across diverse gut microbiomes
#microsky
www.nature.com/articles/s41...
#NewResearch
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants
#microsky
www.nature.com/articles/s41...
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants
#microsky
www.nature.com/articles/s41...
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants - Nature Microbiology
Metagenomes from prairie soils in Kansas, USA, show how historical exposure to water stress impacts soil microorganisms and subsequently drought responses in plants.
www.nature.com
November 5, 2025 at 3:42 PM
#NewResearch
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants
#microsky
www.nature.com/articles/s41...
Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants
#microsky
www.nature.com/articles/s41...
#NewResearch
Anoxia activates CRISPR–Cas immunity in the mouse intestine
www.nature.com/articles/s41...
#microsky
Anoxia activates CRISPR–Cas immunity in the mouse intestine
www.nature.com/articles/s41...
#microsky
Anoxia activates CRISPR–Cas immunity in the mouse intestine - Nature Microbiology
The Citrobacter rodentium CRISPR–Cas system is activated by the oxygen-responsive transcriptional regulator Fnr in the anoxic environment of the mouse gut.
www.nature.com
November 5, 2025 at 3:41 PM
#NewResearch
Anoxia activates CRISPR–Cas immunity in the mouse intestine
www.nature.com/articles/s41...
#microsky
Anoxia activates CRISPR–Cas immunity in the mouse intestine
www.nature.com/articles/s41...
#microsky
#NewResearch
A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people
@greening.bsky.social
#microsky
www.nature.com/articles/s41...
A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people
@greening.bsky.social
#microsky
www.nature.com/articles/s41...
A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people - Nature Microbiology
A previously uncharacterized microbial enzyme is responsible for the production of molecular hydrogen in the gut, which drives the growth of other bacteria and has implications for human health.
www.nature.com
November 5, 2025 at 3:40 PM
#NewResearch
A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people
@greening.bsky.social
#microsky
www.nature.com/articles/s41...
A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people
@greening.bsky.social
#microsky
www.nature.com/articles/s41...
Read our November editorial:
The complex path towards herpesvirus vaccines
www.nature.com/articles/s41...
The complex path towards herpesvirus vaccines
www.nature.com/articles/s41...
November 5, 2025 at 3:33 PM
Read our November editorial:
The complex path towards herpesvirus vaccines
www.nature.com/articles/s41...
The complex path towards herpesvirus vaccines
www.nature.com/articles/s41...