Greg Jefferis
banner
jefferis.bsky.social
Greg Jefferis
@jefferis.bsky.social
Neural Circuits and Behaviour in Drosophila @ MRC LMB. PI @ flyconnectome @ CamZoology and @ virtualflybrain. Cambridge, UK. Previously @gsxej.
Pinned
Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns?
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8
Reposted by Greg Jefferis
Excited to return as co-director of the CSHL Drosophila 🪰Neurobiology course in 2026!
Application Deadline: March 27
meetings.cshl.edu/courses.aspx...
@cshlnews.bsky.social
@cshlaboratory.bsky.social
@cshlcourses.bsky.social
#cshlflycourse
#scicomm
#drosophila
🪰🧪
Drosophila Neurobiology: Genes, Circuits & Behavior
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
meetings.cshl.edu
November 8, 2025 at 3:47 PM
Reposted by Greg Jefferis
Come join us as a CSHL-Simons Fellow!

supporting bold research programs aimed at tackling fundamental questions across all Neuroscience areas, from NeuroAI to brain body interactions. CSHL Fellows are appointed for 3-5 years and direct their own research groups.

www.cshl.edu/about-us/car...
Fellows Positions | Cold Spring Harbor Laboratory
CSHL Simons Fellow in NEUROSCIENCE Cold Spring Harbor Laboratory (CSHL) is seeking to fill a Cold Spring Harbor Laboratory Fellow position in the area of NEUROSCIENCE (experimental and/or computationa...
www.cshl.edu
October 25, 2025 at 1:17 PM
Reposted by Greg Jefferis
TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 11:28 PM
Reposted by Greg Jefferis
Excited to share our new #biorxivpreprint

We discovered that the fruit fly #drosophila erecta requires food odor to mate and arousal is further enhanced by social group motion.

Cross-species analysis of brain activity reveals a novel gate evolved from within a conserved circuit

shorturl.at/gGYm7
October 16, 2025 at 6:34 AM
Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
October 15, 2025 at 4:17 PM
Reposted by Greg Jefferis
We are recruiting PhD students! If you are interested in evolutionary neuroscience, consider applying: www.crick.ac.uk/careers-stud...
Prieto Godino Lab | Cellular and molecular bases of neural circuit and behavioural evolution
www.crick.ac.uk
October 8, 2025 at 8:51 PM
Reposted by Greg Jefferis
Some fly neurons are “dimorphic”, existing in both males and females but connecting to different neighboring neurons. Neighbors may be “isomorphic”, the same in both male and female; or sex specific; or dimorphic themselves. Here's an example, the type AOTU012, present in left and right instances.
October 8, 2025 at 9:11 AM
Wow congratulations @jkohl.bsky.social! Proud scientific parent :)
The #HertieFoundation and #FENS are excited to announce the winner of the Eric Kandel Young Neuroscientists Prize 2025: Johannes Kohl!

He will be awarded EUR 100,000 and will deliver the Eric Kandel Prize Lecture at #FENS2026 in Barcelona! 🇪🇸

👉 https://loom.ly/xsDFNzo
October 6, 2025 at 9:50 PM
And here's the official announcement from our Janelia collaborators with a fantastic visualisation from @philiphubbard.bsky.social. See more at male-cns.janelia.org/media. Downloads are humming and we have solved the first data access queries. Happy exploring! #drosophila #connectomics #malecns.
October 6, 2025 at 2:59 PM
Reposted by Greg Jefferis
We're very proud to be releasing the complete male fly CNS connectome!

It's the product of a huge team effort here at Janelia in partnership with the Cambridge Fly Connectomics group (@jefferis.bsky.social and colleagues), plus invaluable collaborators.

More soon...
www.janelia.org/project-team...
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
www.janelia.org
October 5, 2025 at 6:02 PM
Exciting news for #drosophila #connectomics and #neuroscience enthusiasts: the Drosophila male central nervous system connectome is now live for exploration. Find out more at the landing page hosted by our Janelia FlyEM collaborators www.janelia.org/project-team....
Male CNS Connectome
A team of researchers has unveiled the complete connectome of a male fruit fly central nervous system —a seamless map of all the neurons in the brain and nerve cord of a single male fruit fly and the ...
www.janelia.org
October 5, 2025 at 3:40 PM
Reposted by Greg Jefferis
Interested in the mechanisms of neurogenesis, and how they might converge/differ across species, regions, and life epochs? Check this out, wonderful location and great science! Please RT

neuro-unige.ch/news/csf-mee...
October 5, 2025 at 12:16 PM
Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns?
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8
August 21, 2025 at 4:04 PM
Reposted by Greg Jefferis
📢 We are hiring! 📢
For our @wellcometrust.bsky.social grant on information gathering biases in #OCD and #Schizophrenia, we are looking for a Postdoc in Computational Modelling, supervised by Peter Dayan and myself.
Interested? See all the details in the job advert here: devcompsy.org/wp-content/u...
a penguin is sticking his head out of a hole next to a job application
ALT: a penguin is sticking his head out of a hole next to a job application
media.tenor.com
August 19, 2025 at 11:32 AM
Reposted by Greg Jefferis
It was a good experience to step back and briefly take stock of the amazing progress in connectomics since I started working on this stuff (20 years ago!)

thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.
August 14, 2025 at 7:40 PM
Reposted by Greg Jefferis
"The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades."

4000 labs is a severe understatement, likely off by an order of magnitude. Even non-fly people use and benefit from FlyBase. It is one of the cornerstones of the genome era.
August 14, 2025 at 5:18 AM
Reposted by Greg Jefferis
With @megyounger.bsky.social's lab, et al., we present the first connectomics work in the disease-vector mosquito Aedes aegypti, revealing how its brain is wired to detect host cues.

Preprint: doi.org/10.1101/2025...

#Neuroscience #Connectomics #vEM #VectorBiology 🧪
August 3, 2025 at 3:51 AM
Reposted by Greg Jefferis
We are looking for 2 postdocs to join my lab at Sussex University in Brighton, UK (South of London, on the sea). One position is for a molecular/cell biologist, the other, for a neurobiologist/behavioural person. Drosophila experience desirable. Flyer w/more info below. Please repost. Thank you!
July 24, 2025 at 9:26 PM
Reposted by Greg Jefferis
We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).
Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology
Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...
www.jobs.ac.uk
July 14, 2025 at 12:10 PM
Reposted by Greg Jefferis
Big story breaking this evening.

Alan Turing Institute told to focus on defence or lose funding.

The science secretary Peter Kyle has threatened to pull defence R&D funds, while reforms could see EPSRC grant revisited.

Free to read.

www.researchprofessionalnews.com/rr-news-uk-p...
Alan Turing Institute told to focus on defence or lose funding - Research Professional News
Science secretary threatens to pull defence R&D funds, while reforms could see EPSRC grant revisited
www.researchprofessionalnews.com
July 4, 2025 at 6:13 PM
Reposted by Greg Jefferis
In our new preprint we describe the synaptic #connectome of the nerve net in the ctenophore gravisensory organ. https://www.biorxiv.org/content/10.1101/2025.06.26.661250v1 #biology #neuroscience #ctenophore #vem
June 30, 2025 at 5:51 AM
Reposted by Greg Jefferis
🎉We are delighted to announce that Professor Stephen Montgomery @ebablab.bsky.social‬ will be the 3rd Prince Philip Professor of Ecology and Evolution.

We look forward to welcoming him next year!
June 18, 2025 at 9:13 AM
Reposted by Greg Jefferis
Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...
June 16, 2025 at 4:18 PM