Piali Sengupta
@senguptalab.bsky.social
Brandeis Bio/Neuro. We study multiple aspects of sensory biology. Mostly in worms. Lab appears to be powered by vast quantities of junk food. Opinions mine.
senguptalab.org
senguptalab.org
Pinned
Piali Sengupta
@senguptalab.bsky.social
· Oct 16
Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
Reposted by Piali Sengupta
As a someone with a 33 year NIH-funded lab whose grant is supposed to be reviewed this week, shut NIH down if that is what's needed to end ICE terrorism. Innocent lives are more important 🧪
The Senate may choose to vote together on the DHS and LHHS bills. Thus, a filibuster on DHS may mean no funding for NIH. What my colleagues are saying:
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
January 25, 2026 at 12:59 PM
As a someone with a 33 year NIH-funded lab whose grant is supposed to be reviewed this week, shut NIH down if that is what's needed to end ICE terrorism. Innocent lives are more important 🧪
Reposted by Piali Sengupta
I cannot imagine the devastation this family is experiencing today. This statement is powerful and must be read.
January 25, 2026 at 1:52 AM
I cannot imagine the devastation this family is experiencing today. This statement is powerful and must be read.
Reposted by Piali Sengupta
California just joined the World Health Organization.
I love it.
I love it.
California joins WHO public health network following US exit, marking a first for any state
California joined WHO's Global Outbreak Alert and Response Network, countering federal withdrawal from the organization.
www.abc10.com
January 23, 2026 at 10:30 PM
California just joined the World Health Organization.
I love it.
I love it.
Reposted by Piali Sengupta
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
January 20, 2026 at 10:53 PM
This is the most astonishing graph of what the Trump regime has done to US science. They have destroyed the federal science workforce across the board. The negative impacts on Americans will be felt for generations, and the US might never be the same again.
www.nature.com/immersive/d4...
www.nature.com/immersive/d4...
Reposted by Piali Sengupta
The conference (agreement between House and Senate) appropriations bill that includes HHS and NIH was released this morning.
www.appropriations.senate.gov/news/majorit...
1/5
www.appropriations.senate.gov/news/majorit...
1/5
Committee Releases Conferenced Defense, Homeland Security, Labor, Health and Human Services, Education, and Related Agencies, and Transportation, Housing and Urban Development, and Related Agencies Bi...
United States Senate Committee on Appropriations
www.appropriations.senate.gov
January 20, 2026 at 3:55 PM
The conference (agreement between House and Senate) appropriations bill that includes HHS and NIH was released this morning.
www.appropriations.senate.gov/news/majorit...
1/5
www.appropriations.senate.gov/news/majorit...
1/5
@currentbiology.bsky.social does it again. The video is a must watch 🤣. Smart bovine!
Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a “multi-purpose tool” to scratch herself. A video and more information will follow in the comments.
www.cell.com/current-biol...
www.cell.com/current-biol...
January 19, 2026 at 7:54 PM
@currentbiology.bsky.social does it again. The video is a must watch 🤣. Smart bovine!
Reposted by Piali Sengupta
Reposted by Piali Sengupta
I enjoyed reading these 20 reviews in this special edition on interoception. This exciting field of brain-body signaling has many open questions – indicated by most articles written by PIs of labs opened within the past few years. Nice job authors and editors.
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Current Opinion in Neurobiology | Interoception 2025 | ScienceDirect.com by Elsevier
Read the latest articles of Current Opinion in Neurobiology at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
January 9, 2026 at 2:09 PM
I enjoyed reading these 20 reviews in this special edition on interoception. This exciting field of brain-body signaling has many open questions – indicated by most articles written by PIs of labs opened within the past few years. Nice job authors and editors.
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
my god it's only jan 7th. how are we going to get through the rest of this year
January 8, 2026 at 12:45 AM
my god it's only jan 7th. how are we going to get through the rest of this year
26 degrees out and snow on the ground? No matter. First job accomplished for 2026 was putting up the hammock in the family room. Panacea for existential stress.
January 1, 2026 at 10:48 PM
26 degrees out and snow on the ground? No matter. First job accomplished for 2026 was putting up the hammock in the family room. Panacea for existential stress.
Reposted by Piali Sengupta
Blog post: Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com
December 30, 2025 at 3:02 PM
Blog post: Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Iguana thermoregulation.
(This is not Boston)
(This is not Boston)
December 28, 2025 at 5:58 PM
Iguana thermoregulation.
(This is not Boston)
(This is not Boston)
Reposted by Piali Sengupta
Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪
December 19, 2025 at 7:17 PM
Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪
Reposted by Piali Sengupta
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Self-renewal of neuronal mitochondria through asymmetric division
Mitochondrial ATP production is essential for life. Mitochondrial function depends on the spatio-temporal coordination of nuclear and mitochondrial genome expression, yet how this coordination occurs ...
www.biorxiv.org
December 18, 2025 at 8:36 PM
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Is it better to decline a paper review invitation if you are swamped, or accept and then sit on it for >2 months? Asking for a friend...
December 18, 2025 at 1:58 PM
Is it better to decline a paper review invitation if you are swamped, or accept and then sit on it for >2 months? Asking for a friend...
Reposted by Piali Sengupta
In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neurons @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
December 16, 2025 at 10:57 PM
In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neurons @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Today's collection of headlines makes me want to curl up in a ball under a blanket in a sensory deprivation chamber. 2026 had better be better or else...
December 16, 2025 at 1:54 PM
Today's collection of headlines makes me want to curl up in a ball under a blanket in a sensory deprivation chamber. 2026 had better be better or else...
Reposted by Piali Sengupta
Explore the first seven parts of American Science, Shattered
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
American Science, Shattered
An eight-decade partnership between universities and the federal government made U.S. science preeminent. It took Trump less than a year to shred that
www.statnews.com
December 14, 2025 at 9:35 PM
Explore the first seven parts of American Science, Shattered
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
Reposted by Piali Sengupta
Our hearts are with the students, staff, and families at Brown.
We don’t have to live this way.
#BrownUniversity
We don’t have to live this way.
#BrownUniversity
December 14, 2025 at 3:47 PM
Our hearts are with the students, staff, and families at Brown.
We don’t have to live this way.
#BrownUniversity
We don’t have to live this way.
#BrownUniversity
Afternoon tea to warm ourselves up and to usher in the holidays.
December 12, 2025 at 11:41 PM
Afternoon tea to warm ourselves up and to usher in the holidays.
Reposted by Piali Sengupta
I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...
PAR-26-121: Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)
files.simpler.grants.gov
December 11, 2025 at 6:48 PM
I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...
🤣🤣🤣 but also of course really 😥
(But read the comments!)
(But read the comments!)
The NIH is seeking leadership via Facebook ad. The comments are spectacular.
www.facebook.com/share/1AAWyg...
www.facebook.com/share/1AAWyg...
December 10, 2025 at 1:42 AM
🤣🤣🤣 but also of course really 😥
(But read the comments!)
(But read the comments!)
Reposted by Piali Sengupta
The best books of 2025
The best books of 2025
New novels from Chimamanda Ngozi Adichie and Ian McEwan, plus the return of Slow Horses and Margaret Atwood looks back … Guardian critics pick the must-read titles of 2025
www.theguardian.com
December 6, 2025 at 11:09 AM
The best books of 2025
Mango cream, sweet potato, pecan, two cherry.
Not sure we made enough.
Not sure we made enough.
November 27, 2025 at 4:18 AM
Mango cream, sweet potato, pecan, two cherry.
Not sure we made enough.
Not sure we made enough.
Check out the newest Editors' (that would be me and Eunjoon Kim) Choice issue in Current Opinion in Neurobiology.
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Current Opinion in Neurobiology | Interoception 2025 | ScienceDirect.com by Elsevier
Read the latest articles of Current Opinion in Neurobiology at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
November 25, 2025 at 1:29 PM
Check out the newest Editors' (that would be me and Eunjoon Kim) Choice issue in Current Opinion in Neurobiology.
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...