Piali Sengupta
@senguptalab.bsky.social
Brandeis Bio/Neuro. We study multiple aspects of sensory biology. Mostly in worms. Lab appears to be powered by vast quantities of junk food. Opinions mine.
senguptalab.org
senguptalab.org
Pinned
Piali Sengupta
@senguptalab.bsky.social
· Oct 16
Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc!
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email.
Please RT 🙏
26 degrees out and snow on the ground? No matter. First job accomplished for 2026 was putting up the hammock in the family room. Panacea for existential stress.
January 1, 2026 at 10:48 PM
26 degrees out and snow on the ground? No matter. First job accomplished for 2026 was putting up the hammock in the family room. Panacea for existential stress.
Reposted by Piali Sengupta
Blog post: Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com
December 30, 2025 at 3:02 PM
Blog post: Just quit
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Quitting projects in science is hard, but we should be doing a lot more of it.
open.substack.com/pub/arjunraj...
Iguana thermoregulation.
(This is not Boston)
(This is not Boston)
December 28, 2025 at 5:58 PM
Iguana thermoregulation.
(This is not Boston)
(This is not Boston)
Reposted by Piali Sengupta
Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪
December 19, 2025 at 7:17 PM
Hey all, I reached out to the PO of my NIGMS MIRA to ask if the gov't shut down, and rescheduling of study sections, might allow for some accommodation to the standard rule that PIs cannot resubmit a MIRA while their MIRA (or other RPG) is under review (waiting in scores or summary statements) 🧪
Reposted by Piali Sengupta
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Self-renewal of neuronal mitochondria through asymmetric division
Mitochondrial ATP production is essential for life. Mitochondrial function depends on the spatio-temporal coordination of nuclear and mitochondrial genome expression, yet how this coordination occurs ...
www.biorxiv.org
December 18, 2025 at 8:36 PM
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Is it better to decline a paper review invitation if you are swamped, or accept and then sit on it for >2 months? Asking for a friend...
December 18, 2025 at 1:58 PM
Is it better to decline a paper review invitation if you are swamped, or accept and then sit on it for >2 months? Asking for a friend...
Reposted by Piali Sengupta
In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neurons @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
December 16, 2025 at 10:57 PM
In vivo transcriptomic, functional, circuit-based, and translational analyses of enteric neurons @cellcellpress.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Today's collection of headlines makes me want to curl up in a ball under a blanket in a sensory deprivation chamber. 2026 had better be better or else...
December 16, 2025 at 1:54 PM
Today's collection of headlines makes me want to curl up in a ball under a blanket in a sensory deprivation chamber. 2026 had better be better or else...
Reposted by Piali Sengupta
Explore the first seven parts of American Science, Shattered
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
American Science, Shattered
An eight-decade partnership between universities and the federal government made U.S. science preeminent. It took Trump less than a year to shred that
www.statnews.com
December 14, 2025 at 9:35 PM
Explore the first seven parts of American Science, Shattered
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
A multipart series on how the Trump administration has disrupted labs, upended lives, and delayed discoveries.
www.statnews.com/american-sci...
Reposted by Piali Sengupta
Our hearts are with the students, staff, and families at Brown.
We don’t have to live this way.
#BrownUniversity
We don’t have to live this way.
#BrownUniversity
December 14, 2025 at 3:47 PM
Our hearts are with the students, staff, and families at Brown.
We don’t have to live this way.
#BrownUniversity
We don’t have to live this way.
#BrownUniversity
Afternoon tea to warm ourselves up and to usher in the holidays.
December 12, 2025 at 11:41 PM
Afternoon tea to warm ourselves up and to usher in the holidays.
Reposted by Piali Sengupta
I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...
PAR-26-121: Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)
files.simpler.grants.gov
December 11, 2025 at 6:48 PM
I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...
🤣🤣🤣 but also of course really 😥
(But read the comments!)
(But read the comments!)
The NIH is seeking leadership via Facebook ad. The comments are spectacular.
www.facebook.com/share/1AAWyg...
www.facebook.com/share/1AAWyg...
December 10, 2025 at 1:42 AM
🤣🤣🤣 but also of course really 😥
(But read the comments!)
(But read the comments!)
Reposted by Piali Sengupta
The best books of 2025
The best books of 2025
New novels from Chimamanda Ngozi Adichie and Ian McEwan, plus the return of Slow Horses and Margaret Atwood looks back … Guardian critics pick the must-read titles of 2025
www.theguardian.com
December 6, 2025 at 11:09 AM
The best books of 2025
Mango cream, sweet potato, pecan, two cherry.
Not sure we made enough.
Not sure we made enough.
November 27, 2025 at 4:18 AM
Mango cream, sweet potato, pecan, two cherry.
Not sure we made enough.
Not sure we made enough.
Check out the newest Editors' (that would be me and Eunjoon Kim) Choice issue in Current Opinion in Neurobiology.
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Current Opinion in Neurobiology | Interoception 2025 | ScienceDirect.com by Elsevier
Read the latest articles of Current Opinion in Neurobiology at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
November 25, 2025 at 1:29 PM
Check out the newest Editors' (that would be me and Eunjoon Kim) Choice issue in Current Opinion in Neurobiology.
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Superbly guest edited by Stephen Liberles and @zknight.bsky.social
>20 review articles on Interoception
www.sciencedirect.com/special-issu...
Reposted by Piali Sengupta
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
November 25, 2025 at 6:18 AM
Read this inspiring perspectives coauthored by the Worm Resource directors and worm Nobel Laureates! 4 Nobel Prizes and how they were enabled by major NIH-supported research resources (the Caenorhabditis Genetics Center, WormBase, and WormAtlas) www.pnas.org/doi/10.1073/...
Reposted by Piali Sengupta
Boston's Mayor Wu playing with Yo-Yo Ma at Symphony Hall
November 23, 2025 at 5:11 AM
Boston's Mayor Wu playing with Yo-Yo Ma at Symphony Hall
Anyone else obsessively checking to see if the NIGMS EI MIRA NOFO has been posted? Nah - just me? Expired in 2025 and the forecast said would be posted Nov 3rd. But ofc there was the shutdown in between.
a woman covering her mouth with her hands while wearing headphones
ALT: a woman covering her mouth with her hands while wearing headphones
media.tenor.com
November 21, 2025 at 11:02 PM
Anyone else obsessively checking to see if the NIGMS EI MIRA NOFO has been posted? Nah - just me? Expired in 2025 and the forecast said would be posted Nov 3rd. But ofc there was the shutdown in between.
Reposted by Piali Sengupta
Thanks to @nature.com for featuring our work in this piece on genetically-encoded sensors.
The article does a great job highlighting their importance for both basic research and translational impact, such as in our lab's research on serotonin.
www.nature.com/articles/d41...
The article does a great job highlighting their importance for both basic research and translational impact, such as in our lab's research on serotonin.
www.nature.com/articles/d41...
How genetically encoded sensors have lit up neuroscience
Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.
www.nature.com
November 21, 2025 at 5:56 PM
Thanks to @nature.com for featuring our work in this piece on genetically-encoded sensors.
The article does a great job highlighting their importance for both basic research and translational impact, such as in our lab's research on serotonin.
www.nature.com/articles/d41...
The article does a great job highlighting their importance for both basic research and translational impact, such as in our lab's research on serotonin.
www.nature.com/articles/d41...
Reposted by Piali Sengupta
Reposted by Piali Sengupta
Re-upping this - Neuropeeps! We have a TT Job in my wonderful department at Brandeis! First consideration to applications received by Dec 15 (but why wait?)
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Assistant Professor in Biology and Neuroscience Program - Waltham, Massachusetts (US) job with Brandeis University | 12848464
The Department of Biology and the Program in Neuroscience at Brandeis University invite applications for a tenure-track Assistant Professor positio...
www.nature.com
November 20, 2025 at 3:03 PM
Re-upping this - Neuropeeps! We have a TT Job in my wonderful department at Brandeis! First consideration to applications received by Dec 15 (but why wait?)
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Piali Sengupta
Come do a joint postdoc with me and @tinakim-neuro.bsky.social, splitting your time between Princeton and Columbia. Come design new activity-dependent labeling enzymes and transcriptional reporters optimized for application in the peripheral nervous system.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
Postdoctoral Scientist- Kim and Abdus-Saboor Lab
Primary Work Address: Dept of Molecular Biology, Princeton, NJ, 08544 Current HHMI Employees, click here to apply via your Workday account. The Kim Lab at Princeton University and Abdus-Saboor Lab at ...
hhmi.wd1.myworkdayjobs.com
November 17, 2025 at 5:34 PM
Come do a joint postdoc with me and @tinakim-neuro.bsky.social, splitting your time between Princeton and Columbia. Come design new activity-dependent labeling enzymes and transcriptional reporters optimized for application in the peripheral nervous system.
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
hhmi.wd1.myworkdayjobs.com/en-US/Extern...
All of you knowledgeable music-lovers on here - I need recommendations to rejuvenate my workout playlist (to keep my mind off my aching everything). Gravitate towards high energy sounds - punk, metal (thrash, power, prog mostly but not death), industrial, but will try out other genres. 🙏
November 16, 2025 at 6:55 PM
All of you knowledgeable music-lovers on here - I need recommendations to rejuvenate my workout playlist (to keep my mind off my aching everything). Gravitate towards high energy sounds - punk, metal (thrash, power, prog mostly but not death), industrial, but will try out other genres. 🙏
Reposted by Piali Sengupta
If you’re at #sfn25 you definitely don’t want to miss this nanosymposium on cilia, tomorrow from 1-4pm! Come learn about neuronal cilia, they do some pretty cool stuff!
Synapses may get all the glory, but join us cilia-philes for our @sfn.org Nanosymposium to learn about the role of cilia in modulating brain activity, behavior, and development.
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
November 15, 2025 at 8:26 PM
If you’re at #sfn25 you definitely don’t want to miss this nanosymposium on cilia, tomorrow from 1-4pm! Come learn about neuronal cilia, they do some pretty cool stuff!