Cell-extrinsic cues are key for neocortical cell identity and diversity.

The choroid plexus (ChP) provides molecular cues for brain development. However, the underlying mechanisms are unclear. This study identifies an apocrine secretion mechanism in the ChP that modulates ...

Facial expressions are critical social signals, essential for human communication. This study used EEG to investigate the neural dynamics of the processing of emotional expressions in real and emoji faces, using a data-driven approach. Across two experiments with identical paradigms, two separate sets of participants viewed facial expressions (happy, angry, sad, neutral) in real faces (4 female and 4 male identities, n = 24) or emojis (6 platforms, n = 25) while performing a two-alternative forced-choice emotion recognition task. Time-resolved multivariate classification and spatio-temporal searchlight analyses revealed robust decoding of emotional expressions within and across experiments. Consistent effects emerged early and peaked between 145-160 ms over posterior-occipital and parietal regions. Notably, robust cross-classification between real and emoji faces demonstrated that face-like emoji stimuli evoke neural responses comparable to those elicited by real faces, with more sustained effects over right posterior sites. These findings suggest that the brain uses overlapping spatio-temporal codes for naturalistic and symbolic facial expressions, providing new insights into the neural coding of social signals and the representational overlap between natural and artificial emotional expressions. ### Competing Interest Statement The authors have declared no competing interest.

The cortex is organized along macroscale structural and functional gradients that extend from unimodal to transmodal association areas and from somatosensory to visual regions. It has not been tested ...

Proper brain function requires the precise assembly of neural circuits during development. Despite the identification of many cell-surface proteins (CSPs) that help guide axons to their targets, it re...

We present the first causal evidence in healthy humans linking central thalamus to vigilance and pulvinar to visuospatial attention using low-intensity transcranial focused ultrasound stimulation (tFU...

Arc Institute today launched the Arc Virtual Cell Atlas, a growing resource for computation-ready single-cell measurements, starting with data from over 300 million cells. The initial release of the A...