Harmit Singh Malik
@harmitmalik.bsky.social
Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results).
Fred Hutch Basic Sciences,
UW Genome Sciences,
HHMI.
Posting in a personal capacity. My posts don’t reflect my employers’ opinions.
Fred Hutch Basic Sciences,
UW Genome Sciences,
HHMI.
Posting in a personal capacity. My posts don’t reflect my employers’ opinions.
Pinned
Reposted by Harmit Singh Malik
My wife and I pay for life insurance even though we have never died. I pay for fire insurance even though my house has never burned down. That's not because we want to throw money at insurance companies. It's because THAT'S HOW INSURANCE WORKS.
November 10, 2025 at 3:44 PM
My wife and I pay for life insurance even though we have never died. I pay for fire insurance even though my house has never burned down. That's not because we want to throw money at insurance companies. It's because THAT'S HOW INSURANCE WORKS.
So if I’ve got this right, ordinary Americans in all
walks of life got squeezed for 40 days so that we could somehow win …
what exactly?
Except that no one will ever take the threat of shutdown from the Dems seriously ever again
walks of life got squeezed for 40 days so that we could somehow win …
what exactly?
Except that no one will ever take the threat of shutdown from the Dems seriously ever again
November 11, 2025 at 4:15 AM
So if I’ve got this right, ordinary Americans in all
walks of life got squeezed for 40 days so that we could somehow win …
what exactly?
Except that no one will ever take the threat of shutdown from the Dems seriously ever again
walks of life got squeezed for 40 days so that we could somehow win …
what exactly?
Except that no one will ever take the threat of shutdown from the Dems seriously ever again
Reposted by Harmit Singh Malik
For #Readers: The Rory Gilmore Reading Challenge is pretty darn great. It has the 339 books (novels, nonfiction, plays, poetry) that Rory of the The Gilmore Girls* is shown reading. I'm only at 23% so I need to get to steppin'.
* I've haven't seen an episode...yet.
share.google/2IBopgRRRtpf...
* I've haven't seen an episode...yet.
share.google/2IBopgRRRtpf...
The Rory Gilmore Reading Challenge
Over the course of seven seasons of Gilmore Girls, Rory Gilmore was seen reading 339 books on screen. How many have you read?
From...
share.google
November 10, 2025 at 10:48 PM
For #Readers: The Rory Gilmore Reading Challenge is pretty darn great. It has the 339 books (novels, nonfiction, plays, poetry) that Rory of the The Gilmore Girls* is shown reading. I'm only at 23% so I need to get to steppin'.
* I've haven't seen an episode...yet.
share.google/2IBopgRRRtpf...
* I've haven't seen an episode...yet.
share.google/2IBopgRRRtpf...
Reposted by Harmit Singh Malik
this is literally never not accurate
November 10, 2025 at 6:32 PM
this is literally never not accurate
Reposted by Harmit Singh Malik
Design stable, folded proteins using only the 10 "ancient" amino acids.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 31, 2025 at 7:40 PM
Design stable, folded proteins using only the 10 "ancient" amino acids.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Too close
November 10, 2025 at 10:47 PM
Too close
Reposted by Harmit Singh Malik
Thank you so much to @entsocamerica.bsky.social for this honour of being a #fellow! We celebrated with Voodoo donuts!
November 10, 2025 at 1:49 PM
Thank you so much to @entsocamerica.bsky.social for this honour of being a #fellow! We celebrated with Voodoo donuts!
Reposted by Harmit Singh Malik
It was lovely speaking to @harmitmalik.bsky.social for @dmmjournal.bsky.social Infectious Disease Special Issue. We chatted about his work on host-viral evolution, the importance of blue-skies research and his approach to creating a supportive lab environment
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
For our #InfectiousDisease Special Issue we interviewed the marvelous @harmitmalik.bsky.social ! We discussed the #viral arms race, how to support mentees and the beauty of basic science 🔬
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
The viral arms race: an interview with Harmit Malik
Harmit Malik. Photo credit: Fred Hutchinson Cancer Research Center.Harmit Malik is Professor and Associate Director of the Basic Sciences Division at the Fred Hutchinson Cancer Center in Seattle, WA,…
journals.biologists.com
November 10, 2025 at 4:13 PM
It was lovely speaking to @harmitmalik.bsky.social for @dmmjournal.bsky.social Infectious Disease Special Issue. We chatted about his work on host-viral evolution, the importance of blue-skies research and his approach to creating a supportive lab environment
journals.biologists.com/dmm/article/...
journals.biologists.com/dmm/article/...
Reposted by Harmit Singh Malik
A really nice telling of the rise of Arabidopsis - mentioning so many of my heroes! We should be grateful for their vision and persistence.
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
✍️ Rachel Ehrenberg
knowmag.org/4hImL8e
✍️ Rachel Ehrenberg
knowmag.org/4hImL8e
How a humble weed became a superstar of biology
Arabidopsis thaliana was always an unlikely candidate for the limelight. But 25 years ago, the diminutive thale cress launched the botanical world into the molecular era.
knowmag.org
November 5, 2025 at 12:51 PM
A really nice telling of the rise of Arabidopsis - mentioning so many of my heroes! We should be grateful for their vision and persistence.
Democrats in Congress:
Fool me once, shame on you.
Fool me 1700 times, shame on me!
Meanwhile, Russell is going: Promises? Vought promises?!
Fool me once, shame on you.
Fool me 1700 times, shame on me!
Meanwhile, Russell is going: Promises? Vought promises?!
November 10, 2025 at 12:31 AM
Democrats in Congress:
Fool me once, shame on you.
Fool me 1700 times, shame on me!
Meanwhile, Russell is going: Promises? Vought promises?!
Fool me once, shame on you.
Fool me 1700 times, shame on me!
Meanwhile, Russell is going: Promises? Vought promises?!
Reposted by Harmit Singh Malik
Getting very strong LOB vibes from this version of the @seahawksofficial.com defense
November 9, 2025 at 10:01 PM
Getting very strong LOB vibes from this version of the @seahawksofficial.com defense
Reposted by Harmit Singh Malik
“Secretary of Homeland Security Kristi Noem reportedly authorized the purchase of 10 Spirit Airlines planes before she realized that the airlines didn’t own the planes. Also, none of the planes came with engines.”
“Merit based hiring” my @$$. 🙄
“Merit based hiring” my @$$. 🙄
November 9, 2025 at 5:14 AM
“Secretary of Homeland Security Kristi Noem reportedly authorized the purchase of 10 Spirit Airlines planes before she realized that the airlines didn’t own the planes. Also, none of the planes came with engines.”
“Merit based hiring” my @$$. 🙄
“Merit based hiring” my @$$. 🙄
Reposted by Harmit Singh Malik
We are through the looking glass, people
Marjorie Taylor Greene said she took Amtrak train instead as shutdown cancels flights
As many as 20% of flights could be canceled if the government shutdown continues, Transportation Secretary Sean Duffy said this week.
www.usatoday.com
November 9, 2025 at 11:05 AM
We are through the looking glass, people
Reposted by Harmit Singh Malik
There’s a cult of ignorance in the US and always has been.
The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that “my ignorance is just as good as your knowledge.”
- Isaac Asimov
The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that “my ignorance is just as good as your knowledge.”
- Isaac Asimov
November 8, 2025 at 6:13 PM
There’s a cult of ignorance in the US and always has been.
The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that “my ignorance is just as good as your knowledge.”
- Isaac Asimov
The strain of anti-intellectualism has been a constant thread winding its way through our political and cultural life, nurtured by the false notion that democracy means that “my ignorance is just as good as your knowledge.”
- Isaac Asimov
Reposted by Harmit Singh Malik
It's weird. A hundred years ago, only rich people owned cars while everyone else owned horses. Now only rich people own horses while everyone else owns cars.
How the stables have turned.
How the stables have turned.
November 8, 2025 at 7:14 PM
It's weird. A hundred years ago, only rich people owned cars while everyone else owned horses. Now only rich people own horses while everyone else owns cars.
How the stables have turned.
How the stables have turned.
A well meaning relative called me on Sunday (late) morning and chided me for still being in bed. They encouraged me to do all the things I planned for the day. I replied that, until they called to wake me up, that is precisely what I was doing and will return to doing after I hung up.
#Sundaygoals
#Sundaygoals
November 9, 2025 at 6:42 PM
A well meaning relative called me on Sunday (late) morning and chided me for still being in bed. They encouraged me to do all the things I planned for the day. I replied that, until they called to wake me up, that is precisely what I was doing and will return to doing after I hung up.
#Sundaygoals
#Sundaygoals
Reposted by Harmit Singh Malik
The Next Gen Pregnancy Initiative is now accepting applications. Up to $500,000 over 4 years to support bold research into pregnancy duration, fetal growth, and pregnancy complications. Deadline: Dec 4, 2025.
Apply now buff.ly/rNhJKMW #bwfrepro
Apply now buff.ly/rNhJKMW #bwfrepro
Next Gen Pregnancy Initiative - Burroughs Wellcome Fund
by
buff.ly
October 7, 2025 at 9:33 AM
The Next Gen Pregnancy Initiative is now accepting applications. Up to $500,000 over 4 years to support bold research into pregnancy duration, fetal growth, and pregnancy complications. Deadline: Dec 4, 2025.
Apply now buff.ly/rNhJKMW #bwfrepro
Apply now buff.ly/rNhJKMW #bwfrepro
Reposted by Harmit Singh Malik
Trump's tariffs are hurting us in two ways:
First, the obvious: Higher costs → either lower profits or higher prices.
Second, more subtle (perhaps bigger): We’ve signaled we’re an unreliable partner, so allies are reorganizing supply chains to avoid us. That's hard to unwind.
First, the obvious: Higher costs → either lower profits or higher prices.
Second, more subtle (perhaps bigger): We’ve signaled we’re an unreliable partner, so allies are reorganizing supply chains to avoid us. That's hard to unwind.
November 8, 2025 at 1:51 PM
Trump's tariffs are hurting us in two ways:
First, the obvious: Higher costs → either lower profits or higher prices.
Second, more subtle (perhaps bigger): We’ve signaled we’re an unreliable partner, so allies are reorganizing supply chains to avoid us. That's hard to unwind.
First, the obvious: Higher costs → either lower profits or higher prices.
Second, more subtle (perhaps bigger): We’ve signaled we’re an unreliable partner, so allies are reorganizing supply chains to avoid us. That's hard to unwind.
Reposted by Harmit Singh Malik
Picard: there ARE FOUR GUYS! FOUR
November 3, 2025 at 4:48 PM
Picard: there ARE FOUR GUYS! FOUR
Reposted by Harmit Singh Malik
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
November 7, 2025 at 11:02 AM
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
Reposted by Harmit Singh Malik
10/10 take. No notes.
November 7, 2025 at 5:49 PM
10/10 take. No notes.
Reposted by Harmit Singh Malik
Unlocking secrets of #meiosis! Wei et al. reveal how Mei5-Sae3 complex enhances Dmc1p assembly by stabilizing Dmc1p clusters on ssDNA, altering RPA dynamics, paving way for successful interhomolog recombination. Fascinating proteins in action! #yeast #Genetics www.yeastgenome.org/reference/39...
November 7, 2025 at 11:45 PM
Unlocking secrets of #meiosis! Wei et al. reveal how Mei5-Sae3 complex enhances Dmc1p assembly by stabilizing Dmc1p clusters on ssDNA, altering RPA dynamics, paving way for successful interhomolog recombination. Fascinating proteins in action! #yeast #Genetics www.yeastgenome.org/reference/39...
When people celebrate the individual genius of folks in science, they should also
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
November 7, 2025 at 11:43 PM
When people celebrate the individual genius of folks in science, they should also
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)