Oscar J. Abilez
@oscarabilez.bsky.social
Stem cell/organoid bioengineer modeling CV development@Stanford | Co-Founder@bullseyebio | MD@Cornell, PhD@Stanford, BSME @UTAustin | husband, father, occasional jogger
Reposted by Oscar J. Abilez
Researchers are making ever more sophisticated mini organs in the lab — and now they can grow their own blood vessels
go.nature.com/4nNF3ri
go.nature.com/4nNF3ri
Mini hearts, lungs and livers made in lab now grow their own blood vessels
These sophisticated models will be used for human-development studies and drug testing.
go.nature.com
July 11, 2025 at 11:12 AM
Researchers are making ever more sophisticated mini organs in the lab — and now they can grow their own blood vessels
go.nature.com/4nNF3ri
go.nature.com/4nNF3ri
Reposted by Oscar J. Abilez
June 26, 2025 at 9:40 PM
Reposted by Oscar J. Abilez
Drs. @oscarabilez.bsky.social, Huaxiao 'Adam' Yang, and a team in Dr. Joseph Wu's lab generated vascularized cardiac and hepatic #organoids!
Read the @science.org paper: bit.ly/3FBuHtr
Listen to the discussion: bit.ly/4kRfsMk
Read the @science.org paper: bit.ly/3FBuHtr
Listen to the discussion: bit.ly/4kRfsMk
June 16, 2025 at 5:34 PM
Drs. @oscarabilez.bsky.social, Huaxiao 'Adam' Yang, and a team in Dr. Joseph Wu's lab generated vascularized cardiac and hepatic #organoids!
Read the @science.org paper: bit.ly/3FBuHtr
Listen to the discussion: bit.ly/4kRfsMk
Read the @science.org paper: bit.ly/3FBuHtr
Listen to the discussion: bit.ly/4kRfsMk
Reposted by Oscar J. Abilez
🧬 Breakthrough in Organoid Vascularization!
A major step forward in modeling human development 🔬
Stanford reseachers have successfully created vascularized cardiac and hepatic organoids from human pluripotent stem cells, mimicking early human organ development with remarkable fidelity.
A major step forward in modeling human development 🔬
Stanford reseachers have successfully created vascularized cardiac and hepatic organoids from human pluripotent stem cells, mimicking early human organ development with remarkable fidelity.
Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization
Although model organisms have provided insight into the earliest stages of cardiac and hepatic vascularization, we know very little about this process in humans because of ethical restrictions and the...
www.science.org
June 11, 2025 at 9:02 PM
🧬 Breakthrough in Organoid Vascularization!
A major step forward in modeling human development 🔬
Stanford reseachers have successfully created vascularized cardiac and hepatic organoids from human pluripotent stem cells, mimicking early human organ development with remarkable fidelity.
A major step forward in modeling human development 🔬
Stanford reseachers have successfully created vascularized cardiac and hepatic organoids from human pluripotent stem cells, mimicking early human organ development with remarkable fidelity.
@appliedcvb.bsky.social, thanks for sharing 😁
Member publication alert:
Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization
www.science.org/doi/10.1126/...
Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization
www.science.org/doi/10.1126/...
Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization
Although model organisms have provided insight into the earliest stages of cardiac and hepatic vascularization, we know very little about this process in humans because of ethical restrictions and the...
www.science.org
June 10, 2025 at 8:29 PM
@appliedcvb.bsky.social, thanks for sharing 😁
Reposted by Oscar J. Abilez
Reposted by Oscar J. Abilez
Pluripotent stem cells that differentiate into vascularized cardiac and hepatic organoids. Wow! www.science.org/doi/10.1126/...
Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization
Although model organisms have provided insight into the earliest stages of cardiac and hepatic vascularization, we know very little about this process in humans because of ethical restrictions and the...
www.science.org
June 6, 2025 at 2:25 AM
Pluripotent stem cells that differentiate into vascularized cardiac and hepatic organoids. Wow! www.science.org/doi/10.1126/...
Full article: Developing advanced organoids: challenges, progress, and outlook www.tandfonline.com/eprint/FITHS...
Developing advanced organoids: challenges, progress, and outlook
Published in BioTechniques (Vol. 76, No. 12, 2024)
www.tandfonline.com
February 7, 2025 at 5:20 PM
Full article: Developing advanced organoids: challenges, progress, and outlook www.tandfonline.com/eprint/FITHS...
Reposted by Oscar J. Abilez
Nature research paper: Engineered heart muscle allografts for heart repair in primates and humans
https://go.nature.com/4hdLyzN
https://go.nature.com/4hdLyzN
Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading to improved cardiac function and paving the way for human clinical trials.
go.nature.com
January 29, 2025 at 5:28 PM
Nature research paper: Engineered heart muscle allografts for heart repair in primates and humans
https://go.nature.com/4hdLyzN
https://go.nature.com/4hdLyzN
Reposted by Oscar J. Abilez
In 2019, the #mesoSPIM and #ctASLM #lightsheet #Microscopy papers appeared back-to-back in @naturemethods.bsky.social - now Jinlong Lin, @zacsimile.bsky.social & @kevin-dean.bsky.social & Co introduce the MCT-ASLM - a chimera of both for smart multiscale #imaging!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 27, 2025 at 8:03 AM
In 2019, the #mesoSPIM and #ctASLM #lightsheet #Microscopy papers appeared back-to-back in @naturemethods.bsky.social - now Jinlong Lin, @zacsimile.bsky.social & @kevin-dean.bsky.social & Co introduce the MCT-ASLM - a chimera of both for smart multiscale #imaging!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Oscar J. Abilez
We've put together a collection of the writers and editors who work on news, features, opinion and research at Nature magazine. Follow them all here:
go.bsky.app/JARysRt 🧪
go.bsky.app/JARysRt 🧪
January 8, 2025 at 4:37 PM
We've put together a collection of the writers and editors who work on news, features, opinion and research at Nature magazine. Follow them all here:
go.bsky.app/JARysRt 🧪
go.bsky.app/JARysRt 🧪
Reposted by Oscar J. Abilez
Extremely cool system for in vitro culture!
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific
morphogen gradients and systematically guide in vitro development
Congrats to everyone involved!
www.cell.com/cell/abstrac...
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific
morphogen gradients and systematically guide in vitro development
Congrats to everyone involved!
www.cell.com/cell/abstrac...
Synthetic organizer cells guide development via spatial and biochemical instructions
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific morphogen gradients and systematically guide in vitro development.
www.cell.com
December 19, 2024 at 8:01 PM
Extremely cool system for in vitro culture!
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific
morphogen gradients and systematically guide in vitro development
Congrats to everyone involved!
www.cell.com/cell/abstrac...
Synthetic organizer cells, engineered to spatially self-assemble around stem cells, can be used to create specific
morphogen gradients and systematically guide in vitro development
Congrats to everyone involved!
www.cell.com/cell/abstrac...
Reposted by Oscar J. Abilez
Wow, how #cardiosky has grown!
Our first starter pack is already full, see if you've missed anyone: go.bsky.app/562nfhZ
Our first starter pack is already full, see if you've missed anyone: go.bsky.app/562nfhZ
November 20, 2024 at 9:16 AM
Wow, how #cardiosky has grown!
Our first starter pack is already full, see if you've missed anyone: go.bsky.app/562nfhZ
Our first starter pack is already full, see if you've missed anyone: go.bsky.app/562nfhZ
Reposted by Oscar J. Abilez
The biofabrication of human tissues requires a combination of engineering control and intrinsic self-assembly. In their Review, Sarah Heilshorn et al discuss how cells and organoids can be characterized as a living material and manipulated by biofabrication techniques go.nature.com/3ZJadEL
Organoid bioprinting: from cells to functional tissues - Nature Reviews Bioengineering
Integrating bioprinting with organoid technology can enhance tissue engineering by improving complexity, reproducibility and scalability. This Review discusses living materials in bioprinting, current...
go.nature.com
December 18, 2024 at 12:20 PM
The biofabrication of human tissues requires a combination of engineering control and intrinsic self-assembly. In their Review, Sarah Heilshorn et al discuss how cells and organoids can be characterized as a living material and manipulated by biofabrication techniques go.nature.com/3ZJadEL
Reposted by Oscar J. Abilez
One of the biggest questions we get is when will our journals be here. We thank you for your patience.
You can now follow our journals with this starter pack!
You can now follow our journals with this starter pack!
December 18, 2024 at 2:57 PM
One of the biggest questions we get is when will our journals be here. We thank you for your patience.
You can now follow our journals with this starter pack!
You can now follow our journals with this starter pack!
Reposted by Oscar J. Abilez
If you share our enthusiasm for #regeneration, share, follow, and (self-)nominate people to the list.
🧪
go.bsky.app/MGXL9Ra
🧪
go.bsky.app/MGXL9Ra
November 13, 2024 at 12:46 PM
If you share our enthusiasm for #regeneration, share, follow, and (self-)nominate people to the list.
🧪
go.bsky.app/MGXL9Ra
🧪
go.bsky.app/MGXL9Ra
Reposted by Oscar J. Abilez
🧪 We have made it easier to follow our journals and community sites with our new starter pack.
https://go.bsky.app/BwC3bSV
https://go.bsky.app/BwC3bSV
December 15, 2024 at 10:15 AM
🧪 We have made it easier to follow our journals and community sites with our new starter pack.
https://go.bsky.app/BwC3bSV
https://go.bsky.app/BwC3bSV
Reposted by Oscar J. Abilez
December 15, 2024 at 10:23 PM
Reposted by Oscar J. Abilez
The Living Materials & Tissue Engineering community continues to grow on Bluesky. So great to see more colleagues over here AND to met new/rising stars in our community.
Lets keep growing & sharing our work.
And let me know others to add including self-nominations!
go.bsky.app/AeG8FWr
Lets keep growing & sharing our work.
And let me know others to add including self-nominations!
go.bsky.app/AeG8FWr
November 26, 2024 at 5:22 PM
The Living Materials & Tissue Engineering community continues to grow on Bluesky. So great to see more colleagues over here AND to met new/rising stars in our community.
Lets keep growing & sharing our work.
And let me know others to add including self-nominations!
go.bsky.app/AeG8FWr
Lets keep growing & sharing our work.
And let me know others to add including self-nominations!
go.bsky.app/AeG8FWr
Reposted by Oscar J. Abilez
Here's a starter pack that focuses on engineers/builders/makers/enablers of optical tools for (cell) biology.
I'm pretty sure that the pack is incomplete - if you want to join the list, please reply with your favorite probe (that you made or used) and I'll add you 🤓
go.bsky.app/2YVvYER
I'm pretty sure that the pack is incomplete - if you want to join the list, please reply with your favorite probe (that you made or used) and I'll add you 🤓
go.bsky.app/2YVvYER
November 11, 2024 at 7:27 PM
Here's a starter pack that focuses on engineers/builders/makers/enablers of optical tools for (cell) biology.
I'm pretty sure that the pack is incomplete - if you want to join the list, please reply with your favorite probe (that you made or used) and I'll add you 🤓
go.bsky.app/2YVvYER
I'm pretty sure that the pack is incomplete - if you want to join the list, please reply with your favorite probe (that you made or used) and I'll add you 🤓
go.bsky.app/2YVvYER
Reposted by Oscar J. Abilez
It's woefully incomplete, but I've made the start of a starter pack for folks interested in microscopy. Suggestions for who else to include (including yourself!) are very welcome.
go.bsky.app/SaYfAX3
go.bsky.app/SaYfAX3
September 19, 2024 at 4:35 PM
It's woefully incomplete, but I've made the start of a starter pack for folks interested in microscopy. Suggestions for who else to include (including yourself!) are very welcome.
go.bsky.app/SaYfAX3
go.bsky.app/SaYfAX3
Reposted by Oscar J. Abilez
Interested in microscopy and/or image analysis? Check out my newest starter pack of super folks.(which also links to the previous, 150-awesome-full one! Both also link to other imaging-y starter packs as I find them)
go.bsky.app/MU8c2A2
go.bsky.app/MU8c2A2
November 14, 2024 at 2:00 PM
Interested in microscopy and/or image analysis? Check out my newest starter pack of super folks.(which also links to the previous, 150-awesome-full one! Both also link to other imaging-y starter packs as I find them)
go.bsky.app/MU8c2A2
go.bsky.app/MU8c2A2
Reposted by Oscar J. Abilez
In the process, came across a great one from @dmikeando.bsky.social , at a skim I suspect they are closer to 1 than 2 circles as a venn diagram but have not (and probably will not going forward) troubled to diff and cross-reg. Check his out too! go.bsky.app/SaYfAX3
November 6, 2024 at 9:03 PM
In the process, came across a great one from @dmikeando.bsky.social , at a skim I suspect they are closer to 1 than 2 circles as a venn diagram but have not (and probably will not going forward) troubled to diff and cross-reg. Check his out too! go.bsky.app/SaYfAX3
Reposted by Oscar J. Abilez
If you're interested in systems biology, check out the Systems Biology Starter Pack! Contact me if you'd like to be added. go.bsky.app/7P14HFu
November 9, 2024 at 3:21 PM
If you're interested in systems biology, check out the Systems Biology Starter Pack! Contact me if you'd like to be added. go.bsky.app/7P14HFu
Reposted by Oscar J. Abilez
105 cool microscopists in this starter pack, but I know there are more out there! I want to find more 45 to complete the list, can you help me? 🤓🔬
go.bsky.app/Aaf8sKT
go.bsky.app/Aaf8sKT
November 21, 2024 at 6:30 PM
105 cool microscopists in this starter pack, but I know there are more out there! I want to find more 45 to complete the list, can you help me? 🤓🔬
go.bsky.app/Aaf8sKT
go.bsky.app/Aaf8sKT