Lightnews — Scholar-powered news

Yan Leyfman, MD

@yleyfman.bsky.social

1.1K followers 650 following 600 posts

Posts Replies Media Videos

Pinned

Yan Leyfman, MD @yleyfman.bsky.social · Nov 12

What sets MedNews Week apart? What are some exciting future initiatives?

Check out our latest feature for an exclusive behind-the-scenes look at the impact we're aiming to make with our unique partnership with Global Education Leader OncLive!

www.onclive.com/view/park-an...

Park and Leyfman Hope to Advance Mission of MedNews Week Through Collaboration With OncLive

Chandler Park, MD, FACP, and Yan Leyfman, MD, discuss their partnership with OncLive and future goals for MedNews Week.

www.onclive.com

Yan Leyfman, MD

@yleyfman.bsky.social

🧠💥 Decoding how opioids relieve pain—beyond sensation

New work reveals how the anterior cingulate cortex (ACC) encodes the affective dimension of chronic pain—and how opioids selectively modulate this circuit.

Mimicking opioid analgesia in cortical pain circuits - Nature

The anterior cingulate cortex encodes affective pain behaviours modulated by opioids; targeting opioid-sensitive neurons through a new chemogenetic gene therapy replicates the analgesic effects of mor...

www.nature.com

January 17, 2026 at 3:52 AM

Yan Leyfman, MD

@yleyfman.bsky.social

🦴🧬 Precision RNA delivery for osteoarthritis

Intra-articular RNA therapeutics hold promise in OA—but efficacy hinges on getting the therapy to the right cartilage, at the right disease stage.

Client Challenge

www.nature.com

January 15, 2026 at 12:26 AM

Yan Leyfman, MD

@yleyfman.bsky.social

🧠🔊 Mapping consciousness with precision

A new review highlights transcranial focused ultrasound (tFUS) as a breakthrough, non-invasive tool for probing the neural basis of conscious perception in humans.

Transcranial focused ultrasound for identifying the neural substrate of conscious perception

Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While pro…

www.sciencedirect.com

January 14, 2026 at 5:51 AM

Yan Leyfman, MD

@yleyfman.bsky.social

CAR-T saves lives—but we’re still missing the full picture 🧩

In Episode 8 of The Translational Edge, we dive into a novel method 🔬 that could transform how we monitor CAR-T cells in patients—answering long-standing questions about persistence, trafficking, and real-time response 📊

Shuf.ai

Shuf turns any medical content into a new format with AI so that you can increase your audience

www.shuf.ai

January 13, 2026 at 6:53 PM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

Adipose Manipulation Transplantation as a New Cancer Therapy Platform - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Yan Leyfman: Adipose Manipulation Transplantation as a New Cancer Therapy Platform - OncoDaily

Yan Leyfman: Adipose Manipulation Transplantation as a New Cancer Therapy Platform / cancer, OncoDaily, Oncology, Pancreatic Cancer, Yan Leyfman

oncodaily.com

December 28, 2025 at 7:49 PM

Reposted by Yan Leyfman, MD

Yan Leyfman, MD

@yleyfman.bsky.social

🚀 Join the Expanding MedNews Week Team!

MedNews Week is a global virtual medical education platform reaching 100+ countries and 40,000+ attendees per event.

December 21, 2025 at 5:08 AM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

Uncovering Site-Specific Immune and Stromal Differences in Primary and Metastatic PDAC - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #PDAC

Yan Leyfman: Uncovering Site-Specific Immune and Stromal Differences in Primary and Metastatic PDAC - OncoDaily

Yan Leyfman: Uncovering Site-Specific Immune and Stromal Differences in Primary and Metastatic PDAC / Alyssa M. Krasinskas, Ayana T. Ruffin, Bassel F.

oncodaily.com

December 22, 2025 at 9:31 PM

Yan Leyfman, MD

@yleyfman.bsky.social

🚀 Join the Expanding MedNews Week Team!

MedNews Week is a global virtual medical education platform reaching 100+ countries and 40,000+ attendees per event.

December 21, 2025 at 5:08 AM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

New Evidence Highlights the Power of the Patient Voice in Oncology - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Yan Leyfman: New Evidence Highlights the Power of the Patient Voice in Oncology - OncoDaily

Yan Leyfman: New Evidence Highlights the Power of the Patient Voice in Oncology / Ali Benour, Andrea Bezjak, Andrew Mihalache, cancer, Carlton Johnny, David

oncodaily.com

November 29, 2025 at 10:48 PM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

MedNews Week Celebrates 4-Year Anniversary - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Yan Leyfman: MedNews Week Celebrates 4-Year Anniversary - OncoDaily

Yan Leyfman: MedNews Week Celebrates 4-Year Anniversary / Alexandra Van de Kieft, Arturo Loaiza-Bonilla, cancer, Chandler H Park, Gayathri Pramil Menon, Ghena

oncodaily.com

December 1, 2025 at 7:03 PM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

A Global, Volunteer Model for Accurate and Inclusive Cancer Education - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Yan Leyfman: A Global, Volunteer Model for Accurate and Inclusive Cancer Education - OncoDaily

Yan Leyfman: A Global, Volunteer Model for Accurate and Inclusive Cancer Education / cancer, MedNews Week, OncoDaily, Oncology, Yan Leyfman

oncodaily.com

December 4, 2025 at 3:50 PM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

Ultra-Processed Foods and Early-Onset Colorectal Neoplasia - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/yan-l...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Yan Leyfman: Ultra-Processed Foods and Early-Onset Colorectal Neoplasia - OncoDaily

Yan Leyfman: Ultra-Processed Foods and Early-Onset Colorectal Neoplasia / Alberto Puccini, cancer, colorectal cancer, Colorectal Neoplasia, David Foureau,

oncodaily.com

November 16, 2025 at 6:17 PM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

Brian Van Tine: The Truly Great Ones Leave Us Far Too Soon - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/voices/brian...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews

Yan Leyfman: Brian Van Tine - The Truly Great Ones Leave Us Far Too Soon - OncoDaily

Yan Leyfman: Brian Van Tine - The Truly Great Ones Leave Us Far Too Soon / Brian Van Tine, cancer, OncoDaily, Oncology, Yan Leyfman

oncodaily.com

November 11, 2025 at 12:21 AM

Yan Leyfman, MD

@yleyfman.bsky.social

In life, we meet many people—many leaders, mentors, and friends—but the truly great ones leave us far too soon.

I met Dr. Brian Van Tine about four years ago at ASCO, and he immediately stood out as one of the most jovial, energetic, and compassionate individuals one could hope to meet.

November 10, 2025 at 3:23 AM

Yan Leyfman, MD

@yleyfman.bsky.social

An important perspective on medical misinformation in the modern era.

www.medscape.com/viewarticle/...

Cancer Misinformation: When Influencers Co-Opt Care

Experts explore the messy intersection between evidence-based cancer care and an enticing wellness industry dominated by social media influencers who often spread cancer misinformation.

www.medscape.com

November 8, 2025 at 4:25 PM

Yan Leyfman, MD

@yleyfman.bsky.social

Thank you to OncLive for the opportunity to share my thoughts on this important update.

www.cancernetwork.com/view/clinica...

@onclive.bsky.social

Clinical Implications Remain After Dasatinib CRL in CML/ALL | CancerNetwork

The FDA's CRL for the HyNap formulation of dasatinib due to manufacturing issues does not affect the efficacy or availability of standard dasatinib.

www.cancernetwork.com

October 30, 2025 at 5:33 AM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

Honored to Join the Advisory Board of CancerNetwork - Yan Leyfman

@yleyfman.bsky.social

oncodaily.com/career/advis...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #CancerNetwork

Yan Leyfman: Honored to Join the Advisory Board of CancerNetwork - OncoDaily

Yan Leyfman: Honored to Join the Advisory Board of CancerNetwork / cancer, CancerNetwork, OncoDaily, Oncology, ONCOLOGY/CancerNetwork, Yan Leyfman

oncodaily.com

September 24, 2025 at 3:02 PM

Yan Leyfman, MD

@yleyfman.bsky.social

I’m deeply honored to join the Advisory Board of ONCOLOGY / CancerNetwork. 🎉 Thank you to Ariana Pelosci & the editorial team for this invitation — I’m grateful for the opportunity to work alongside such an esteemed group of clinical and scientific leaders. 🙏

September 23, 2025 at 10:53 PM

Yan Leyfman, MD

@yleyfman.bsky.social

Grateful to the Humanity Rx Podcast for highlighting my story, my passion for oncology & my commitment to advancing patient care & research innovation.

As one of the few remaining survivors of the after-effects of Chernobyl, my own complex medical journey as a child shaped my path toward medicine.

pod.link

September 3, 2025 at 4:25 AM

Reposted by Yan Leyfman, MD

OncoDaily

@oncodaily.bsky.social

Yan Leyfman: FDA Accepts Bristol Myers Squibb’s Breyanzi for Priority Review as a Potential Treatment for Relapsed MZL

@yleyfman.bsky.social @bristolmyerssquibb.bsky.social

oncodaily.com/voices/yan-l...

#Cancer #Oncology #OncoDaily #Health #Medicine

Yan Leyfman: FDA Accepts Bristol Myers Squibb's Breyanzi for Priority Review as a Potential Treatment for Relapsed MZL - OncoDaily

Yan Leyfman: FDA Accepts Bristol Myers Squibb's Breyanzi for Priority Review as a Potential Treatment for Relapsed MZL / Bristol Myers Squibb, cancer, FDA,

oncodaily.com

August 10, 2025 at 7:09 PM

Yan Leyfman, MD

@yleyfman.bsky.social

🎥 MedNews Week x OncLive x Women in Lymphoma Present:

🌟 Voices in Lymphoma: Women Shaping Care 🌟

Career Development & Mentorship in Medicine

🗓️ Tuesday, August 12

⏰ 6:30 PM EST

August 6, 2025 at 4:31 AM

Yan Leyfman, MD

@yleyfman.bsky.social

🧪 Real-world study supports talquetamab as a viable bridging strategy to BCMA CAR-T in RRMM 🔄

📌 Key Takeaways:

Talquetamab bridging is feasible, safe, and effective, enabling rapid disease control with low-grade toxicities.

Sequential Targeting in Multiple Myeloma: Talquetamab, a GPRC5D bispecific antibody, as a Bridge to BCMA CAR-T cell therapy

Key Points. Talquetamab bridging is feasible, safe and effective allowing rapid disease control with minimal grade toxicity.Talquetamab enabled transition

ashpublications.org

August 2, 2025 at 11:00 PM

Yan Leyfman, MD

@yleyfman.bsky.social

🧬✨ Hope Through Mitochondrial Donation

A UK reproductive program offering pronuclear transfer (a form of mitochondrial donation) to women with pathogenic mtDNA variants has resulted in 8 healthy live births.

Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease | NEJM

Pathogenic variants in mitochondrial DNA (mtDNA) are a common cause of severe, often fatal, inherited metabolic disease. A reproductive care pathway was implemented to provide women carrying pathog...

www.nejm.org

July 27, 2025 at 3:36 PM

Yan Leyfman, MD

@yleyfman.bsky.social

🎥 MedNews Week x OncLive x Women in Lymphoma Present:

🌟 Voices in Lymphoma: Women Shaping Care 🌟

💡 Follicular Lymphoma: General Concept and First Line Strategies

🗓️ Tuesday, July 15

⏰ 6:30 PM EST