Nature
@nature.com
Research, news, and commentary from Nature, the international science journal. For daily science news, get Nature Briefing: https://go.nature.com/get-Nature-Briefing
These are the 25 highest-cited papers published this century, and why they are breaking records
go.nature.com/4qc9pnH
go.nature.com/4qc9pnH
Exclusive: the most-cited papers of the twenty-first century
A Nature analysis reveals the 25 highest-cited papers published this century and explores why they are breaking records.
go.nature.com
December 26, 2025 at 11:04 AM
These are the 25 highest-cited papers published this century, and why they are breaking records
go.nature.com/4qc9pnH
go.nature.com/4qc9pnH
A molecule designed to activate iron locked up in lysosomes and induce cell death might offer a way to tackle treatment-resistant cancer
go.nature.com/4oXWEvY
go.nature.com/4oXWEvY
Lipid-degrading small molecule kills cancer cells by ferroptosis
A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer.
go.nature.com
December 26, 2025 at 10:20 AM
A molecule designed to activate iron locked up in lysosomes and induce cell death might offer a way to tackle treatment-resistant cancer
go.nature.com/4oXWEvY
go.nature.com/4oXWEvY
Some reasons to be cheerful about 2025: drug discovery, progress in gene editing, and conservation
go.nature.com/4pViuRS
go.nature.com/4pViuRS
Seven feel-good science stories to restore your faith in 2025
Nature - Immense progress in gene-editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025.
go.nature.com
December 25, 2025 at 4:36 PM
Some reasons to be cheerful about 2025: drug discovery, progress in gene editing, and conservation
go.nature.com/4pViuRS
go.nature.com/4pViuRS
Demogorgons, Shadow Monsters and psychokinetically gifted 12-year-olds are strictly fictional creations - but what about the parallel universe at the core of Stranger Things?
go.nature.com/48Mo2br
go.nature.com/48Mo2br
Are we living in a parallel universe? The strange physics of Stranger Things
Nature - Nature speaks to theoretical physicists to explore the real theories that inspired the hit series. Warning: contains spoilers.
go.nature.com
December 25, 2025 at 3:26 PM
Demogorgons, Shadow Monsters and psychokinetically gifted 12-year-olds are strictly fictional creations - but what about the parallel universe at the core of Stranger Things?
go.nature.com/48Mo2br
go.nature.com/48Mo2br
It's the Nature Podcast festive spectacular 2025! Listen in for science-themed gifts, games, seasonal songs, and Nature's 10 🎅
go.nature.com/4oZvyEI
go.nature.com/4oZvyEI
The Nature Podcast festive spectacular 2025
Nature - Hear the biggest stories from the world of science | 17 December 2025
go.nature.com
December 25, 2025 at 2:03 PM
It's the Nature Podcast festive spectacular 2025! Listen in for science-themed gifts, games, seasonal songs, and Nature's 10 🎅
go.nature.com/4oZvyEI
go.nature.com/4oZvyEI
Do you know your vampire fungus from your migratory moths?
Take the News & Views end-of-year quiz!
go.nature.com/4oUR8Kp
Take the News & Views end-of-year quiz!
go.nature.com/4oUR8Kp
Take the News & Views end-of-year quiz: vampire fungus, migratory moths and a 160-year-old mystery
Nature - Try these 12 questions to test your knowledge of News & Views and Research Briefing articles published in 2025.
go.nature.com
December 25, 2025 at 12:37 PM
Do you know your vampire fungus from your migratory moths?
Take the News & Views end-of-year quiz!
go.nature.com/4oUR8Kp
Take the News & Views end-of-year quiz!
go.nature.com/4oUR8Kp
The rise of AI scientists, missions to explore the moons of Earth and Mars and a massive ocean-floor drill are among the developments set to shape research in 2026
go.nature.com/4amVOp1
go.nature.com/4amVOp1
Science in 2026: the events to watch for in the coming year
The rise of AI scientists, missions to explore the moons of Earth and Mars and a massive ocean-floor drill are among the developments set to shape research in 2026.
go.nature.com
December 25, 2025 at 11:04 AM
The rise of AI scientists, missions to explore the moons of Earth and Mars and a massive ocean-floor drill are among the developments set to shape research in 2026
go.nature.com/4amVOp1
go.nature.com/4amVOp1
Nature research paper: Astrocyte CCN1 stabilizes neural circuits in the adult brain
go.nature.com/3KWK2Hw
go.nature.com/3KWK2Hw
Astrocyte CCN1 stabilizes neural circuits in the adult brain - Nature
Neural circuits in adult mouse visual cortex are stabilized by astrocytes, which secrete CCN1, resulting in reduced plasticity and increased maturation of multiple cell types.
go.nature.com
December 24, 2025 at 3:36 PM
Nature research paper: Astrocyte CCN1 stabilizes neural circuits in the adult brain
go.nature.com/3KWK2Hw
go.nature.com/3KWK2Hw
A powerful and unbiased way to identify links between genetic variants and biological traits has changed scientists’ understanding of complex diseases and how to treat them
go.nature.com/4s1lL3M
go.nature.com/4s1lL3M
Twenty years of genome-wide association studies
The first robust association between a genetic variant and disease risk.
go.nature.com
December 24, 2025 at 1:43 PM
A powerful and unbiased way to identify links between genetic variants and biological traits has changed scientists’ understanding of complex diseases and how to treat them
go.nature.com/4s1lL3M
go.nature.com/4s1lL3M
"The benefits [of risky play for children] are so broad in terms of social, physical, mental development and mental health, I don’t think we can underestimate the value"
go.nature.com/3Yfyv9r
go.nature.com/3Yfyv9r
Why kids need to take more risks: science reveals the benefits of wild, free play
Studies reveal how risky play can benefit child development. But encouraging it can be a challenge for parents.
go.nature.com
December 24, 2025 at 11:08 AM
"The benefits [of risky play for children] are so broad in terms of social, physical, mental development and mental health, I don’t think we can underestimate the value"
go.nature.com/3Yfyv9r
go.nature.com/3Yfyv9r
Earlier this year, DeepSeek made the bombshell announcement of their R1 model, the powerful but cheap 'reasoning' LLM
Liang Wenfeng, DeepSeek founder and CEO, is part of Nature’s 10, a list of people who shaped science in 2025
go.nature.com/48X0e3v
Liang Wenfeng, DeepSeek founder and CEO, is part of Nature’s 10, a list of people who shaped science in 2025
go.nature.com/48X0e3v
The Chinese finance whizz whose DeepSeek AI model stunned the world
Nature - Liang Wenfeng is part of Nature’s 10, a list of people who shaped science in 2025.
go.nature.com
December 24, 2025 at 10:10 AM
Earlier this year, DeepSeek made the bombshell announcement of their R1 model, the powerful but cheap 'reasoning' LLM
Liang Wenfeng, DeepSeek founder and CEO, is part of Nature’s 10, a list of people who shaped science in 2025
go.nature.com/48X0e3v
Liang Wenfeng, DeepSeek founder and CEO, is part of Nature’s 10, a list of people who shaped science in 2025
go.nature.com/48X0e3v
Looking out of the Fendouzhe submersible, more than nine kilometres below the ocean surface, Mengran Du knew she was seeing something totally new to science
Mengran Du is part of Nature’s 10 2025, our list of people who shaped science this year
go.nature.com/4rSSc4e
Mengran Du is part of Nature’s 10 2025, our list of people who shaped science this year
go.nature.com/4rSSc4e
9,000 metres under the sea: this researcher found the deepest animal ecosystems on Earth
Nature - Mengran Du is part of Nature’s 10, a list of people who shaped science in 2025.
go.nature.com
December 23, 2025 at 12:46 PM
Looking out of the Fendouzhe submersible, more than nine kilometres below the ocean surface, Mengran Du knew she was seeing something totally new to science
Mengran Du is part of Nature’s 10 2025, our list of people who shaped science this year
go.nature.com/4rSSc4e
Mengran Du is part of Nature’s 10 2025, our list of people who shaped science this year
go.nature.com/4rSSc4e
Evidence for a previously overlooked route for microplastics to enter crops and reach plant tissues has implications for ecology and human health
go.nature.com/49fkoH6
go.nature.com/49fkoH6
Airborne microplastics enter plant leaves and end up in our food
Evidence for a previously overlooked route for microplastics to enter crops and reach plant tissues has implications for ecology and human health.
go.nature.com
December 23, 2025 at 9:50 AM
Evidence for a previously overlooked route for microplastics to enter crops and reach plant tissues has implications for ecology and human health
go.nature.com/49fkoH6
go.nature.com/49fkoH6
An in vivo imaging technique can track the way molecules move through the nuclear pore complex
go.nature.com/3KODM4A
go.nature.com/3KODM4A
Live-cell super-resolution microscopy reveals how molecules enter and exit the nucleus
The nuclear pore complex is the gateway to the nucleus of cells. Now an in vivo imaging technique can track the way in which molecules move through this complex.
go.nature.com
December 22, 2025 at 4:38 PM
An in vivo imaging technique can track the way molecules move through the nuclear pore complex
go.nature.com/3KODM4A
go.nature.com/3KODM4A
Susan Monarez was fired after less than a month as Director of the CDC for holding the line on scientific integrity
She is part of Nature's 10 - our list of people who shaped science in 2025
go.nature.com/4pJXoGh
She is part of Nature's 10 - our list of people who shaped science in 2025
go.nature.com/4pJXoGh
The top US health director who stood up for science — and was fired
Nature - Susan Monarez is part of Nature’s 10, a list of people who shaped science in 2025.
go.nature.com
December 22, 2025 at 3:47 PM
Susan Monarez was fired after less than a month as Director of the CDC for holding the line on scientific integrity
She is part of Nature's 10 - our list of people who shaped science in 2025
go.nature.com/4pJXoGh
She is part of Nature's 10 - our list of people who shaped science in 2025
go.nature.com/4pJXoGh
Without clear protocols to catch errors, artificial intelligence’s growing role in science could do more harm than good
go.nature.com/4iZwCXT
go.nature.com/4iZwCXT
Why an overreliance on AI-driven modelling is bad for science
Without clear protocols to catch errors, artificial intelligence’s growing role in science could do more harm than good.
go.nature.com
December 22, 2025 at 2:05 PM
Without clear protocols to catch errors, artificial intelligence’s growing role in science could do more harm than good
go.nature.com/4iZwCXT
go.nature.com/4iZwCXT
Curious about using artificial intelligence to boost your research? Here are the programs you shouldn’t miss
go.nature.com/48Z7vjr
go.nature.com/48Z7vjr
AI for research: the ultimate guide to choosing the right tool
Curious about using artificial intelligence to boost your research? Here are the programs you shouldn’t miss.
go.nature.com
December 22, 2025 at 10:10 AM
Curious about using artificial intelligence to boost your research? Here are the programs you shouldn’t miss
go.nature.com/48Z7vjr
go.nature.com/48Z7vjr
Nature research paper: Visualizing interaction-driven restructuring of quantum Hall edge states
go.nature.com/3N5akI5
go.nature.com/3N5akI5
Visualizing interaction-driven restructuring of quantum Hall edge states - Nature
Scanning tunnelling microscopy is used to image pristine electrostatically defined quantum Hall edge states in graphene with high spatial resolution and demonstrate their interaction-driven restructuring.
go.nature.com
December 22, 2025 at 9:26 AM
Nature research paper: Visualizing interaction-driven restructuring of quantum Hall edge states
go.nature.com/3N5akI5
go.nature.com/3N5akI5
