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cagricevrim.bsky.social
Çağrı Çevrim
@cagricevrim.bsky.social
regeneration | evo-devo | menstruation

Postdoc @ Harvard SCRB
Former BIF PhD fellow @ IGFL (Lyon, FR)
BSc & MSc @ Boğaziçi University (Ist, TR)
Pinned
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
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If you know postdocs in the US whose work is restricted or becoming difficult, there are new fellowship possibilities in the south of Germany. Please, forward this information to them:

uni-freiburg.de/frias/call-f...

Our lab in Freiburg can also serve as a host — happy to discuss options.
Call for Applications: Early Career Rescue Fellowship – Freiburg Institute for Advanced Studies
uni-freiburg.de
November 13, 2025 at 12:31 PM
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Are you an early-stage graduate student (2nd or 3rd year) or early-stage postdoc based in the US or Canada, working primarily in Drosophila? Would you like to help improve the experience of all trainees working in Drosophila research? If so, read on.

(Please repost to reach a broad audience.)
November 12, 2025 at 4:49 AM
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I’d given up on social media, but I was missing too many cool papers. Case in point: this incredible new study from @cagricevrim.bsky.social and @karalmckinley.bsky.social. Simply amazing!
Lab’s 1st preprint!

Menstruation is understudied due to societal taboos + a biological challenge: mice (a key system for research + drug discovery) don’t menstruate.

@cagricevrim.bsky.social made menstruating mice + used them to discover early events in menstruation.

He is on the job market!
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
November 12, 2025 at 6:29 PM
Reposted by Çağrı Çevrim
My book 'The Tree of Life' is published in the USA and Canada today.

Available as book, on kindle and as audio.

I would be really grateful for reposts.

www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
November 11, 2025 at 12:01 PM
Reposted by Çağrı Çevrim
From an accidental discovery of hidden biology to a new framework to understanding and diagnosing rare disease. Thrilled to share the most recent work from our lab and the amazing Jimmy Ly.

wi.mit.edu/news/alterna...
Alternate proteins from the same gene contribute differently to health and rare disease | Whitehead Institute
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients thro...
wi.mit.edu
November 7, 2025 at 4:14 PM
Meet our 2025 cohort of Next Generation Leaders! For the next 3 years, they will network with other rising stars, participate in professional development, and share their ideas for future research directions.
November 5, 2025 at 10:34 PM
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The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.

The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.

www.leadingedgesymposium.org/apply/
November 5, 2025 at 5:48 PM
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We built a targeted protein degradation–based system to mimic reproductive age-related aneuploidy in young eggs - revealing how chromosome errors associated with female infertility arise with age. 🧬✨
With @jiyeonleem.bsky.social and our team at Yale MCDB.

Read: www.nature.com/articles/s43...
A versatile cohesion manipulation system probes female reproductive age-related egg aneuploidy - Nature Aging
To study pathways that lead to aneuploidy during aging, the authors provide a system that enables cohesion protein depletion in mouse oocytes, mimicking effects that occur during aging. They uncover a...
www.nature.com
November 4, 2025 at 1:17 PM
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🥳 Today marks the start of the lab of former postdoc @florianwollweber.bsky.social at @embl.org Grenoble!
www.embl.org/groups/wollw...
Florian-- we will miss you dearly and wish you much success!

With us, Florian applied multiscale imaging 🔬to Asgard archaea ...👇
November 1, 2025 at 12:41 PM
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🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social
We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny.
#ProtistsOnSky #SciComm #SciSky

www.cell.com/cell/fulltex...
October 31, 2025 at 2:42 PM
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The Wilkinson Lab is open for science! @mskcancercenter.bsky.social

🧬We'll be finding funky new RNA biology, mainly by looking at reverse transcriptases (i.e. the Best Enzymes In The World)🧬

annnd: I'm hiring - come join! Especially postdocs and PhD students - please get in touch (NYC is great)
Wilkinson Lab
We discover and study reverse transcriptases
wilkinsonlab.bio
October 31, 2025 at 7:00 PM
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Please share/repost widely: I have a postdoc position available. Please see ad below and reach out to apply.

academicpositions.harvard.edu/postings/15449
Postdoctoral Fellow in the Capellini Laboratory of Developmental and Evolutionary Genetics
The Department of Human Evolutionary Biology at Harvard University invites applications for a Postdoctoral Fellow in the Evolutionary and Developmental Genetics Laboratory of Dr. Terence D. Capellini....
academicpositions.harvard.edu
October 28, 2025 at 12:18 PM
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Incredible new work from the McKinley Lab @karalmckinley.bsky.social describing menstruating mice and stem cell renewal in the uterus! Congrats to an amazing team 🐭🧬🔬
October 13, 2025 at 5:26 AM
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First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience

Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E

@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
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Genetically controlled induction of menstruation in the mouse is a game changer for both basic and applied research in endometrium and it's disorders.
A really amazing model and a great resource
Kudos @cagricevrim.bsky.social and team for this.
Very excited

www.biorxiv.org/content/10.1...
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 27, 2025 at 6:08 PM
Reposted by Çağrı Çevrim
For over 20 years, the mouse model organism has helped scientists uncover the biology behind human health and disease.

But the mouse reference genomes still have missing pieces.
The first collection of telomere-to-telomere mouse genomes are now available for two key mouse strains.
🧬💻
October 27, 2025 at 11:51 AM
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Lab mice can now have periods like humans
Studies of rodents with a menstrual on/off switch could help people with endometriosis and other disorders
www.science.org/content/arti... @science.org
@biorxivpreprint.bsky.social @karalmckinley.bsky.social
www.biorxiv.org/content/10.1...
October 23, 2025 at 6:43 PM
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How does life evolve to adapt to modern cities?

Out now in Science, my PhD work with @lindymcbr.bsky.social uncovers the ancient origin of the “London Underground mosquito” – one of the most iconic examples of urban adaptation.

🧵(1/n)
@science.org
www.science.org/doi/10.1126/science.ady4515
Ancient origin of an urban underground mosquito
Understanding how life is adapting to urban environments represents an important challenge in evolutionary biology. In this work, we investigate a widely cited example of urban adaptation, Culex pipie...
www.science.org
October 25, 2025 at 4:46 AM
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My lab is seeking two PhD candidates to investigate the function and regulation of endogenous retroviruses in the early stages of human development 🦠👩‍🔬. Apply through the International Max Planck Research School (IMPRS) program: www.molgen.mpg.de/IMPRS/applic.... www.molgen.mpg.de/5094682/Fuey...
[2026] – Endogenous retroviruses in human embryogenesis
www.molgen.mpg.de
October 23, 2025 at 8:31 PM
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How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵

Check our latest preprint
A toolkit for testing membrane-localising tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
www.biorxiv.org
October 23, 2025 at 8:16 AM
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🔬 Limb regeneration depends on regenerative signaling center cells — but how do these cells influence others to proliferate, migrate, or differentiate?
We’re recruiting PhD or Postdoc candidates to explore this with our collaborator @osvaldo-chara.bsky.social !
October 21, 2025 at 6:56 AM
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Pre-print alert 🚨
We answer a longstanding question in the field. Do immune cells cause cerebral malaria?

The answer is YES!!!! And independently of P. falciparum accumulation in the brain.

www.biorxiv.org/cgi/content/...
Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrier
Plasmodium falciparum accumulation at the blood-brain barrier (BBB) is a hallmark of cerebral malaria, a life-threatening complication. Conversely, the contribution of the immune response to vascular ...
www.biorxiv.org
October 21, 2025 at 11:06 AM
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I’m excited to announce the launch of my lab at EPFL in Jan 2026 🎉. We’ll combine evolution & synthetic biology to study and (re)engineer bacterial communication.
I’m recruiting PhD students to start in the first semester of 2026.
Apply via EPFL PhD programs by Nov 1
drive.google.com/file/d/1cm-t...
October 20, 2025 at 6:14 PM
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Today @anthropic.com released PubMed integration for Claude. No hallucinations. Just real science, real data. As a beta tester, this has been game changing— a supercharged research tool. Here are 6 prompts that will transform how you search the literature. A 🧵

www.anthropic.com/news/claude-...
Claude for Life Sciences
Discover how Claude accelerates life sciences research with new scientific connectors, skills, and improved performance for drug discovery and clinical work.
www.anthropic.com
October 20, 2025 at 5:27 PM