Stem Cell Podcast
@stemcellpodcast.com
Join us as we discuss the latest stem cell research, policy, and news with field experts. Brought to you by @stemcell.com.
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🔗 stemcellpodcast.com
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Tune in to our latest episode!
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
The @merihuchlab.bsky.social at @mpi-cbg.de developed patient-specific human periportal liver #assembloids.
Read the @nature.com article: https://go.nature.com/4qpL7Xw
Get the breakdown in this week's episode: https://bit.ly/4p3izlj
Read the @nature.com article: https://go.nature.com/4qpL7Xw
Get the breakdown in this week's episode: https://bit.ly/4p3izlj
December 26, 2025 at 4:13 PM
The @merihuchlab.bsky.social at @mpi-cbg.de developed patient-specific human periportal liver #assembloids.
Read the @nature.com article: https://go.nature.com/4qpL7Xw
Get the breakdown in this week's episode: https://bit.ly/4p3izlj
Read the @nature.com article: https://go.nature.com/4qpL7Xw
Get the breakdown in this week's episode: https://bit.ly/4p3izlj
New in @cp-cellstemcell.bsky.social!
Researchers at ShanghaiTech developed sympathetic ganglion #organoids and heart-forming organoids to study inter-tissue crosstalk. 🗣️
Article: https://bit.ly/4pHS9GX
Discussion: https://bit.ly/4p3izlj
Researchers at ShanghaiTech developed sympathetic ganglion #organoids and heart-forming organoids to study inter-tissue crosstalk. 🗣️
Article: https://bit.ly/4pHS9GX
Discussion: https://bit.ly/4p3izlj
December 24, 2025 at 5:09 PM
New in @cp-cellstemcell.bsky.social!
Researchers at ShanghaiTech developed sympathetic ganglion #organoids and heart-forming organoids to study inter-tissue crosstalk. 🗣️
Article: https://bit.ly/4pHS9GX
Discussion: https://bit.ly/4p3izlj
Researchers at ShanghaiTech developed sympathetic ganglion #organoids and heart-forming organoids to study inter-tissue crosstalk. 🗣️
Article: https://bit.ly/4pHS9GX
Discussion: https://bit.ly/4p3izlj
Tune in to our latest episode!
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
December 23, 2025 at 10:05 PM
Tune in to our latest episode!
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
Dr. Deepak Srivastava from @gladstoneinst.bsky.social talks about his lab's recent work investigating heart defects in Down syndrome, and strategies for delivering therapies to the heart. 🫀
Listen now: https://bit.ly/4p3izlj
We're wrapping up 2025 with none other than Dr. Deepak Srivastava from @gladstoneinst.bsky.social!
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
December 19, 2025 at 10:20 PM
We're wrapping up 2025 with none other than Dr. Deepak Srivastava from @gladstoneinst.bsky.social!
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
His lab recently identified HMGN1 as a key contributor to congenital heart defects associated with Down syndrome. 🫀
Learn more: https://go.nature.com/49ovtpT
Reposted by Stem Cell Podcast
New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10
December 15, 2025 at 2:25 PM
New paper out today at @natneuro.nature.com in collab. with DichgansLab @isd-research.bsky.social @lmumuenchen.bsky.social: We developed a fully #iPSC-derived human model of the #BBB #blood-brain-barrier and applied it to study neurovascular disease (NVD)! #OA PDF here: rdcu.be/eUIl3 Thread👇 1/10
New work from the lab of Dr. Saghi Ghaffari has shown that reversing #lysosomal dysfunction restores youthful state in aged #hematopoietic stem cells.
📘 Read it in @cp-cellstemcell.bsky.social: https://bit.ly/4pv1S2X
🎙️ Listen to the episode: https://bit.ly/4q05JW4
📘 Read it in @cp-cellstemcell.bsky.social: https://bit.ly/4pv1S2X
🎙️ Listen to the episode: https://bit.ly/4q05JW4
December 15, 2025 at 4:16 PM
New work from the lab of Dr. Saghi Ghaffari has shown that reversing #lysosomal dysfunction restores youthful state in aged #hematopoietic stem cells.
📘 Read it in @cp-cellstemcell.bsky.social: https://bit.ly/4pv1S2X
🎙️ Listen to the episode: https://bit.ly/4q05JW4
📘 Read it in @cp-cellstemcell.bsky.social: https://bit.ly/4pv1S2X
🎙️ Listen to the episode: https://bit.ly/4q05JW4
We're bringing you a new study from friend-of-the-show Dr. Cat Jamieson!
It shows the results of HSPC functionally organized multi-omics aging and resilience analyses in 9 astronauts before, during, and after 3 short-duration ISS missions. 🚀
🗒️: https://bit.ly/3YgAs5c
🎧: https://bit.ly/4q05JW4
It shows the results of HSPC functionally organized multi-omics aging and resilience analyses in 9 astronauts before, during, and after 3 short-duration ISS missions. 🚀
🗒️: https://bit.ly/3YgAs5c
🎧: https://bit.ly/4q05JW4
December 12, 2025 at 4:37 PM
We're bringing you a new study from friend-of-the-show Dr. Cat Jamieson!
It shows the results of HSPC functionally organized multi-omics aging and resilience analyses in 9 astronauts before, during, and after 3 short-duration ISS missions. 🚀
🗒️: https://bit.ly/3YgAs5c
🎧: https://bit.ly/4q05JW4
It shows the results of HSPC functionally organized multi-omics aging and resilience analyses in 9 astronauts before, during, and after 3 short-duration ISS missions. 🚀
🗒️: https://bit.ly/3YgAs5c
🎧: https://bit.ly/4q05JW4
From cell fate to The Fate of Ophelia, our listeners have good taste.
Thanks for keeping it 100 in 2025. 💯 See you next year!
#SpotifyWrapped
Thanks for keeping it 100 in 2025. 💯 See you next year!
#SpotifyWrapped
December 11, 2025 at 9:24 PM
From cell fate to The Fate of Ophelia, our listeners have good taste.
Thanks for keeping it 100 in 2025. 💯 See you next year!
#SpotifyWrapped
Thanks for keeping it 100 in 2025. 💯 See you next year!
#SpotifyWrapped
Reposted by Stem Cell Podcast
This looks like an excellent read from @cellysally.bsky.social I think that looking at cell cooperation/synchronization from the lens of clones/phylogenies is something super interesting.
Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"
link.springer.com/article/10.1...
#DevBio 🧪
link.springer.com/article/10.1...
#DevBio 🧪
Keeping up with the neighbours: local synchronisation of cell fate decisions during development - EMBO Reports
Even before the advent of multicellular life, unicellular creatures would communicate with their neighbours to coordinate their behaviours. Multicellular organisms have the particular challenge of orc...
link.springer.com
December 11, 2025 at 6:39 PM
This looks like an excellent read from @cellysally.bsky.social I think that looking at cell cooperation/synchronization from the lens of clones/phylogenies is something super interesting.
In this week's episode, we discuss a new study in which researchers developed a #BloodVesselOrganoid model from #HutchinsonGilford progeria syndrome-mutant human embryonic stem cells. 🔬
Read the @cp-devcell.bsky.social study: https://bit.ly/44BDMvB
Listen to the episode: https://bit.ly/4q05JW4
Read the @cp-devcell.bsky.social study: https://bit.ly/44BDMvB
Listen to the episode: https://bit.ly/4q05JW4
December 11, 2025 at 6:19 PM
In this week's episode, we discuss a new study in which researchers developed a #BloodVesselOrganoid model from #HutchinsonGilford progeria syndrome-mutant human embryonic stem cells. 🔬
Read the @cp-devcell.bsky.social study: https://bit.ly/44BDMvB
Listen to the episode: https://bit.ly/4q05JW4
Read the @cp-devcell.bsky.social study: https://bit.ly/44BDMvB
Listen to the episode: https://bit.ly/4q05JW4
📢 New in @natneuro.nature.com!
A team led by Dr. Tal Sharf (@talsharf.bsky.social) has shown that structured neuronal firing sequences appear in spontaneous activity of human and murine #BrainOrganoids.
🗒️: https://go.nature.com/4rlnpgc
🎧: https://bit.ly/4q05JW4
A team led by Dr. Tal Sharf (@talsharf.bsky.social) has shown that structured neuronal firing sequences appear in spontaneous activity of human and murine #BrainOrganoids.
🗒️: https://go.nature.com/4rlnpgc
🎧: https://bit.ly/4q05JW4
December 10, 2025 at 6:35 PM
📢 New in @natneuro.nature.com!
A team led by Dr. Tal Sharf (@talsharf.bsky.social) has shown that structured neuronal firing sequences appear in spontaneous activity of human and murine #BrainOrganoids.
🗒️: https://go.nature.com/4rlnpgc
🎧: https://bit.ly/4q05JW4
A team led by Dr. Tal Sharf (@talsharf.bsky.social) has shown that structured neuronal firing sequences appear in spontaneous activity of human and murine #BrainOrganoids.
🗒️: https://go.nature.com/4rlnpgc
🎧: https://bit.ly/4q05JW4
📢 Our next episode is out!
We chat with the Father of Organoids, Dr. Hans Clevers (@hansclevers.bsky.social) about transitioning from academia to industry, the challenges of creating a #CellTherapy, and creating #organoids of snake guts and lungs.
🔊 Listen now: https://bit.ly/3Mne9IB
We chat with the Father of Organoids, Dr. Hans Clevers (@hansclevers.bsky.social) about transitioning from academia to industry, the challenges of creating a #CellTherapy, and creating #organoids of snake guts and lungs.
🔊 Listen now: https://bit.ly/3Mne9IB
December 9, 2025 at 6:06 PM
📢 Our next episode is out!
We chat with the Father of Organoids, Dr. Hans Clevers (@hansclevers.bsky.social) about transitioning from academia to industry, the challenges of creating a #CellTherapy, and creating #organoids of snake guts and lungs.
🔊 Listen now: https://bit.ly/3Mne9IB
We chat with the Father of Organoids, Dr. Hans Clevers (@hansclevers.bsky.social) about transitioning from academia to industry, the challenges of creating a #CellTherapy, and creating #organoids of snake guts and lungs.
🔊 Listen now: https://bit.ly/3Mne9IB
📢 You won't want to miss our next episode with Dr. @hansclevers.bsky.social!
Learn about his return to the @hubrechtinstitute.bsky.social and his experience running the Institute of Human Biology at Roche: https://bit.ly/48sIRIV
Learn about his return to the @hubrechtinstitute.bsky.social and his experience running the Institute of Human Biology at Roche: https://bit.ly/48sIRIV
December 8, 2025 at 9:13 PM
📢 You won't want to miss our next episode with Dr. @hansclevers.bsky.social!
Learn about his return to the @hubrechtinstitute.bsky.social and his experience running the Institute of Human Biology at Roche: https://bit.ly/48sIRIV
Learn about his return to the @hubrechtinstitute.bsky.social and his experience running the Institute of Human Biology at Roche: https://bit.ly/48sIRIV
Researchers at the University of Basel developed #BoneMarrow #organoids that recapitulate molecular and cellular features of native endosteal niches, enabling the study of pathophysiological interactions with HSCs.
📝 https://bit.ly/48mU0cH
🗨️ https://bit.ly/48dmghX
📝 https://bit.ly/48mU0cH
🗨️ https://bit.ly/48dmghX
December 5, 2025 at 10:32 PM
Researchers at the University of Basel developed #BoneMarrow #organoids that recapitulate molecular and cellular features of native endosteal niches, enabling the study of pathophysiological interactions with HSCs.
📝 https://bit.ly/48mU0cH
🗨️ https://bit.ly/48dmghX
📝 https://bit.ly/48mU0cH
🗨️ https://bit.ly/48dmghX
Reposted by Stem Cell Podcast
Great to see this published: Fitting dynamical landscape models to single-cell data, creating interpretable maps of cell decision making & developmental logic
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Reconstructing Waddington’s landscape from data | PNAS
The development of a zygote into a functional organism requires that this single progenitor
cell gives rise to numerous distinct cell types. Attemp...
www.pnas.org
December 4, 2025 at 6:29 AM
Great to see this published: Fitting dynamical landscape models to single-cell data, creating interpretable maps of cell decision making & developmental logic
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Reposted by Stem Cell Podcast
Meet Dr. Mingxia Gu, a stem cell biologist who engineers miniature human organs like hearts and lungs to develop personalized treatments.
Read our Q&A to learn about her mission to reverse aging, how her father inspired her and the silver lining to living with face blindness. tinyurl.com/MingxiaGu
Read our Q&A to learn about her mission to reverse aging, how her father inspired her and the silver lining to living with face blindness. tinyurl.com/MingxiaGu
December 4, 2025 at 7:05 PM
Meet Dr. Mingxia Gu, a stem cell biologist who engineers miniature human organs like hearts and lungs to develop personalized treatments.
Read our Q&A to learn about her mission to reverse aging, how her father inspired her and the silver lining to living with face blindness. tinyurl.com/MingxiaGu
Read our Q&A to learn about her mission to reverse aging, how her father inspired her and the silver lining to living with face blindness. tinyurl.com/MingxiaGu
A new @cp-cellstemcell.bsky.social paper reveals a cardio-immune mechanism whereby Clusterin+ #cardiomyocytes reprogram #macrophages to resolve inflammation.
Read the paper: https://bit.ly/3Kn8GR9
Listen to the discussion: https://bit.ly/48dmghX
Read the paper: https://bit.ly/3Kn8GR9
Listen to the discussion: https://bit.ly/48dmghX
December 4, 2025 at 5:15 PM
A new @cp-cellstemcell.bsky.social paper reveals a cardio-immune mechanism whereby Clusterin+ #cardiomyocytes reprogram #macrophages to resolve inflammation.
Read the paper: https://bit.ly/3Kn8GR9
Listen to the discussion: https://bit.ly/48dmghX
Read the paper: https://bit.ly/3Kn8GR9
Listen to the discussion: https://bit.ly/48dmghX
🩸 Dr. Lucrezia della Volpe and a team in Dr. Vijay Sankaran's lab (@bloodgenes.bsky.social) discovered that ferroptosis is a key barrier to HSC survival during ex vivo culture.
Read their @natcellbio.nature.com paper: https://go.nature.com/4ib4Ln6
Listen to the discussion: https://bit.ly/48dmghX
Read their @natcellbio.nature.com paper: https://go.nature.com/4ib4Ln6
Listen to the discussion: https://bit.ly/48dmghX
November 27, 2025 at 4:53 PM
🩸 Dr. Lucrezia della Volpe and a team in Dr. Vijay Sankaran's lab (@bloodgenes.bsky.social) discovered that ferroptosis is a key barrier to HSC survival during ex vivo culture.
Read their @natcellbio.nature.com paper: https://go.nature.com/4ib4Ln6
Listen to the discussion: https://bit.ly/48dmghX
Read their @natcellbio.nature.com paper: https://go.nature.com/4ib4Ln6
Listen to the discussion: https://bit.ly/48dmghX
What a story! 🤯
A team at @ucsandiego.bsky.social grafted ESC-derived spinal cord #neural stem cells into non-human primates with #SpinalCordInjury, improving their hand function.
📎 - https://go.nature.com/3LOQsbG
🎧 - https://bit.ly/48dmghX
A team at @ucsandiego.bsky.social grafted ESC-derived spinal cord #neural stem cells into non-human primates with #SpinalCordInjury, improving their hand function.
📎 - https://go.nature.com/3LOQsbG
🎧 - https://bit.ly/48dmghX
November 26, 2025 at 9:07 PM
What a story! 🤯
A team at @ucsandiego.bsky.social grafted ESC-derived spinal cord #neural stem cells into non-human primates with #SpinalCordInjury, improving their hand function.
📎 - https://go.nature.com/3LOQsbG
🎧 - https://bit.ly/48dmghX
A team at @ucsandiego.bsky.social grafted ESC-derived spinal cord #neural stem cells into non-human primates with #SpinalCordInjury, improving their hand function.
📎 - https://go.nature.com/3LOQsbG
🎧 - https://bit.ly/48dmghX
Don't miss this episode!
Dr. @tvierbuchen.bsky.social from @mskcancercenter.bsky.social discusses his work direct reprogramming #fibroblasts into neurons, and PSC models of #neurodevelopment.
Check it out: https://bit.ly/48dmghX
Dr. @tvierbuchen.bsky.social from @mskcancercenter.bsky.social discusses his work direct reprogramming #fibroblasts into neurons, and PSC models of #neurodevelopment.
Check it out: https://bit.ly/48dmghX
November 26, 2025 at 1:01 AM
Don't miss this episode!
Dr. @tvierbuchen.bsky.social from @mskcancercenter.bsky.social discusses his work direct reprogramming #fibroblasts into neurons, and PSC models of #neurodevelopment.
Check it out: https://bit.ly/48dmghX
Dr. @tvierbuchen.bsky.social from @mskcancercenter.bsky.social discusses his work direct reprogramming #fibroblasts into neurons, and PSC models of #neurodevelopment.
Check it out: https://bit.ly/48dmghX
Our next episode features Dr. @tvierbuchen.bsky.social from @mskcancercenter.bsky.social
Tune in tomorrow to hear about his work on next-generation models of #BrainDevelopment. 🧠
Tune in tomorrow to hear about his work on next-generation models of #BrainDevelopment. 🧠
November 24, 2025 at 11:34 PM
Our next episode features Dr. @tvierbuchen.bsky.social from @mskcancercenter.bsky.social
Tune in tomorrow to hear about his work on next-generation models of #BrainDevelopment. 🧠
Tune in tomorrow to hear about his work on next-generation models of #BrainDevelopment. 🧠
Registration & abstract submission are NOW OPEN for #ISSCR2026, July 8-11 in Montréal!
Join global leaders in stem cell science & regenerative medicine to advance the field together.
@stemcell.com will co-sponsor the hallmark event, continuing a valued partnership.
👉 isscr2026.org
@isscr.org
Join global leaders in stem cell science & regenerative medicine to advance the field together.
@stemcell.com will co-sponsor the hallmark event, continuing a valued partnership.
👉 isscr2026.org
@isscr.org
November 24, 2025 at 2:46 PM
Registration & abstract submission are NOW OPEN for #ISSCR2026, July 8-11 in Montréal!
Join global leaders in stem cell science & regenerative medicine to advance the field together.
@stemcell.com will co-sponsor the hallmark event, continuing a valued partnership.
👉 isscr2026.org
@isscr.org
Join global leaders in stem cell science & regenerative medicine to advance the field together.
@stemcell.com will co-sponsor the hallmark event, continuing a valued partnership.
👉 isscr2026.org
@isscr.org
Reposted by Stem Cell Podcast
Check out the Image of the Month! Human intestinal #organoids or ‘mini-guts,’ provide a laboratory model to study human intestinal epithelial biology and the processes leading to intestinal disease. Courtesy of S Blutt lab, F Sawyer. blogs.bcm.edu/2025/11/20/f... @bcmhouston.bsky.social
Image of the Month: Human intestinal organoid
Human intestinal organoids, also called 'mini-guts,' provide a laboratory model to study human intestinal epithelial biology and the processes leading to intestinal disease.
blogs.bcm.edu
November 20, 2025 at 5:50 PM
Check out the Image of the Month! Human intestinal #organoids or ‘mini-guts,’ provide a laboratory model to study human intestinal epithelial biology and the processes leading to intestinal disease. Courtesy of S Blutt lab, F Sawyer. blogs.bcm.edu/2025/11/20/f... @bcmhouston.bsky.social
Dr. Lu Wang and a team in the @gleesonlab.bsky.social at @ucsandiego.bsky.social generated a brain #organoid atlas from patients with neurodevelopmental disorders. 🗺️
Read the article in @cp-cellstemcell.bsky.social : https://bit.ly/49hIEsK
Learn more in this week's episode: https://bit.ly/4qTwoVL
Read the article in @cp-cellstemcell.bsky.social : https://bit.ly/49hIEsK
Learn more in this week's episode: https://bit.ly/4qTwoVL
November 14, 2025 at 3:53 PM
Dr. Lu Wang and a team in the @gleesonlab.bsky.social at @ucsandiego.bsky.social generated a brain #organoid atlas from patients with neurodevelopmental disorders. 🗺️
Read the article in @cp-cellstemcell.bsky.social : https://bit.ly/49hIEsK
Learn more in this week's episode: https://bit.ly/4qTwoVL
Read the article in @cp-cellstemcell.bsky.social : https://bit.ly/49hIEsK
Learn more in this week's episode: https://bit.ly/4qTwoVL
Reposted by Stem Cell Podcast
Save the date! @isscr.org, @alleninstitute.org & @socdevbio.bsky.social are collaborating to present a 3-day scientific symposium led by early-career scientists. The Stem Cell & Developmental Biology Early Career Symposium will be held September 23-25, 2026 in Seattle, WA. Learn more: bit.ly/4p98dkv
November 13, 2025 at 5:20 PM
Save the date! @isscr.org, @alleninstitute.org & @socdevbio.bsky.social are collaborating to present a 3-day scientific symposium led by early-career scientists. The Stem Cell & Developmental Biology Early Career Symposium will be held September 23-25, 2026 in Seattle, WA. Learn more: bit.ly/4p98dkv