Alejo Rodriguez-Fraticelli
@alejofraticelli.bsky.social
Aging and cancer stem cell heterogeneity - ICREA research professor - Quantitative Stem Cell Dynamics lab
at IRB Barcelona 🇦🇷🇪🇺🇺🇸 fraticellilab.com
at IRB Barcelona 🇦🇷🇪🇺🇺🇸 fraticellilab.com
Pinned
Head, Advanced Genomics Technologies Core Facility (Ref. CF/26/01) - IRB Barcelona
IRB Barcelona invites applications for the position of Head, Advanced Genomics Technologies Core Facility. The successful candidate will report to the Director, Technology Strateg...
recruitment.irbbarcelona.org
🚨WE'RE RECRUITING AT @irbbarcelona.org !!!!
--- ADVANCED GENOMICS FACILITY MANAGER ---
An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!
APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
--- ADVANCED GENOMICS FACILITY MANAGER ---
An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!
APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
🚨WE'RE RECRUITING AT @irbbarcelona.org !!!!
--- ADVANCED GENOMICS FACILITY MANAGER ---
An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!
APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
--- ADVANCED GENOMICS FACILITY MANAGER ---
An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!
APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
Head, Advanced Genomics Technologies Core Facility (Ref. CF/26/01) - IRB Barcelona
IRB Barcelona invites applications for the position of Head, Advanced Genomics Technologies Core Facility. The successful candidate will report to the Director, Technology Strateg...
recruitment.irbbarcelona.org
January 27, 2026 at 2:36 PM
🚨WE'RE RECRUITING AT @irbbarcelona.org !!!!
--- ADVANCED GENOMICS FACILITY MANAGER ---
An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!
APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
--- ADVANCED GENOMICS FACILITY MANAGER ---
An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!
APPLY NOW!!!!
recruitment.irbbarcelona.org/jobs/7124180...
Reposted by Alejo Rodriguez-Fraticelli
Excited to announce that our #PUFFFIN plasmids are finally available on @addgene.bsky.social to make PUFFFIN neighbour labelling even more accessible. You can find the plasmids here www.addgene.org/Sally_Lowell/ and our paper here link.springer.com/article/10.1...
Big thanks @cellysally.bsky.social!
Big thanks @cellysally.bsky.social!
Addgene: Sally Lowell Lab Materials
www.addgene.org
January 26, 2026 at 9:50 AM
Excited to announce that our #PUFFFIN plasmids are finally available on @addgene.bsky.social to make PUFFFIN neighbour labelling even more accessible. You can find the plasmids here www.addgene.org/Sally_Lowell/ and our paper here link.springer.com/article/10.1...
Big thanks @cellysally.bsky.social!
Big thanks @cellysally.bsky.social!
Reposted by Alejo Rodriguez-Fraticelli
⚙️ How does ICREA select researchers?
✔️ Open public call
✔️ Independent international evaluation
✔️ Permanent positions
✔️ Host institutions across Catalonia
📢 20 new positions in the #ICREAcall 2026
👉 More info: https://www.icrea.cat/icrea-call/
✔️ Open public call
✔️ Independent international evaluation
✔️ Permanent positions
✔️ Host institutions across Catalonia
📢 20 new positions in the #ICREAcall 2026
👉 More info: https://www.icrea.cat/icrea-call/
January 26, 2026 at 11:03 AM
⚙️ How does ICREA select researchers?
✔️ Open public call
✔️ Independent international evaluation
✔️ Permanent positions
✔️ Host institutions across Catalonia
📢 20 new positions in the #ICREAcall 2026
👉 More info: https://www.icrea.cat/icrea-call/
✔️ Open public call
✔️ Independent international evaluation
✔️ Permanent positions
✔️ Host institutions across Catalonia
📢 20 new positions in the #ICREAcall 2026
👉 More info: https://www.icrea.cat/icrea-call/
Reposted by Alejo Rodriguez-Fraticelli
Using micropatterning & thousands of hours on the microscope
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
January 25, 2026 at 11:03 AM
Using micropatterning & thousands of hours on the microscope
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
@manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
Reposted by Alejo Rodriguez-Fraticelli
Congratulations to Charles Antony (@cantony07.bsky.social), Research Associate in our lab, for being awarded a 2026 American Society of Hematology (ASH) Fellow to Faculty Scholar Award for his investigations into ribosomal RNA transcription in hematopoiesis! Many thanks to ASH for this honor! #ASH
January 23, 2026 at 7:51 PM
Congratulations to Charles Antony (@cantony07.bsky.social), Research Associate in our lab, for being awarded a 2026 American Society of Hematology (ASH) Fellow to Faculty Scholar Award for his investigations into ribosomal RNA transcription in hematopoiesis! Many thanks to ASH for this honor! #ASH
Reposted by Alejo Rodriguez-Fraticelli
TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread
January 15, 2026 at 12:32 PM
TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread
Reposted by Alejo Rodriguez-Fraticelli
⌛ Increases in human life expectancy are not matched by increased health in old age. In a new review in FEBS Letters, @jetteleng.bsky.social et al. explore research on #hematopoieticstemcell rejuvenation in #ageing.
➡️ doi.org/10.1002/1873-3468.70215
➡️ doi.org/10.1002/1873-3468.70215
January 8, 2026 at 12:01 PM
⌛ Increases in human life expectancy are not matched by increased health in old age. In a new review in FEBS Letters, @jetteleng.bsky.social et al. explore research on #hematopoieticstemcell rejuvenation in #ageing.
➡️ doi.org/10.1002/1873-3468.70215
➡️ doi.org/10.1002/1873-3468.70215
I’m seriously worried about whether to attend conferences in the US this year…. I’m sincerely scared. Am I over-reacting to the news?
January 8, 2026 at 7:19 AM
I’m seriously worried about whether to attend conferences in the US this year…. I’m sincerely scared. Am I over-reacting to the news?
Reposted by Alejo Rodriguez-Fraticelli
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers
The ability to discriminate thousands of odors in our environment requires each olfactory neuron to express a single olfactory receptor from hundreds of available genes. The biochemical mechanism enfo...
www.biorxiv.org
January 5, 2026 at 12:51 PM
This went under the radar but answers a fundamental question in Epigenetics...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How?
Outstanding work from Mathieu Boulard and colleagues
www.biorxiv.org/content/10.6...
Reposted by Alejo Rodriguez-Fraticelli
📢 New extended abstract submission deadline: 6 January 2026! Outstanding speaker list, plus many slots for short talks by students, postdocs, and junior PIs. Join us in March in Barcelona! events.ibecbarcelona.eu/embl-ibec-co...
December 15, 2025 at 10:15 AM
📢 New extended abstract submission deadline: 6 January 2026! Outstanding speaker list, plus many slots for short talks by students, postdocs, and junior PIs. Join us in March in Barcelona! events.ibecbarcelona.eu/embl-ibec-co...
Another landmark, milestone paper. Essential to understand the mechanism of one of the most mysterious and important cancer mutations.
Today's the print release of a #RibackLab and #GoodellLab collaboration— we’re excited to share the visual story behind the science, including the dramatic artwork that inspired how we thought about aberrant function of NPM1c - which occurs in about 1 in 3 adult acute myeloid leukemias (#AML).
December 12, 2025 at 6:37 AM
Another landmark, milestone paper. Essential to understand the mechanism of one of the most mysterious and important cancer mutations.
This looks like an excellent read from @cellysally.bsky.social I think that looking at cell cooperation/synchronization from the lens of clones/phylogenies is something super interesting.
Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"
link.springer.com/article/10.1...
#DevBio 🧪
link.springer.com/article/10.1...
#DevBio 🧪
Keeping up with the neighbours: local synchronisation of cell fate decisions during development - EMBO Reports
Even before the advent of multicellular life, unicellular creatures would communicate with their neighbours to coordinate their behaviours. Multicellular organisms have the particular challenge of orc...
link.springer.com
December 11, 2025 at 6:39 PM
This looks like an excellent read from @cellysally.bsky.social I think that looking at cell cooperation/synchronization from the lens of clones/phylogenies is something super interesting.
Reposted by Alejo Rodriguez-Fraticelli
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Really top speakers next year! You don’t want to miss it! Sign up now!
Very excited to take part in ISCO in Barcelona next year. Looking forward to great discussions and new ideas!
ISCO (Innovations in Single-Cell OMICS) will be back in beautiful Barcelona!
🗓️ 28th/29th of May 2026
📍Barcelona Biomedical Research Park @prbb.org (beachfront!)
Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social
Submit your abstract and present your research!
www.isco-conference.eu
🗓️ 28th/29th of May 2026
📍Barcelona Biomedical Research Park @prbb.org (beachfront!)
Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social
Submit your abstract and present your research!
www.isco-conference.eu
December 6, 2025 at 7:27 PM
Really top speakers next year! You don’t want to miss it! Sign up now!
This time is going to be legendary.
If you know you know!
Don’t miss it!!
If you know you know!
Don’t miss it!!
ISCO (Innovations in Single-Cell OMICS) will be back in beautiful Barcelona!
🗓️ 28th/29th of May 2026
📍Barcelona Biomedical Research Park @prbb.org (beachfront!)
Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social
Submit your abstract and present your research!
www.isco-conference.eu
🗓️ 28th/29th of May 2026
📍Barcelona Biomedical Research Park @prbb.org (beachfront!)
Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social
Submit your abstract and present your research!
www.isco-conference.eu
December 5, 2025 at 7:56 PM
This time is going to be legendary.
If you know you know!
Don’t miss it!!
If you know you know!
Don’t miss it!!
Reposted by Alejo Rodriguez-Fraticelli
Great to see this published: Fitting dynamical landscape models to single-cell data, creating interpretable maps of cell decision making & developmental logic
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Reconstructing Waddington’s landscape from data | PNAS
The development of a zygote into a functional organism requires that this single progenitor
cell gives rise to numerous distinct cell types. Attemp...
www.pnas.org
December 4, 2025 at 6:29 AM
Great to see this published: Fitting dynamical landscape models to single-cell data, creating interpretable maps of cell decision making & developmental logic
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Applied to neural tube patterning, we show how morphogen signals reshape landscapes and drive fate decisions
www.pnas.org/doi/10.1073/...
Reposted by Alejo Rodriguez-Fraticelli
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Reposted by Alejo Rodriguez-Fraticelli
Congratulations, Dr. @alejofraticelli.bsky.social (tag/IRBBarcelona-@icreacommunity.bsky.social)," class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#IRBBarcelona-@icreacommunity.bsky.social), on your appointment as a new @embo.org Young Investigator!
Read more here ➡️ https://shorturl.at/7uh1C
🧪
Read more here ➡️ https://shorturl.at/7uh1C
🧪
December 2, 2025 at 1:02 PM
Congratulations, Dr. @alejofraticelli.bsky.social (tag/IRBBarcelona-@icreacommunity.bsky.social)," class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#IRBBarcelona-@icreacommunity.bsky.social), on your appointment as a new @embo.org Young Investigator!
Read more here ➡️ https://shorturl.at/7uh1C
🧪
Read more here ➡️ https://shorturl.at/7uh1C
🧪
Reposted by Alejo Rodriguez-Fraticelli
Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
December 2, 2025 at 1:06 PM
Congratulations to the new cohort of 28 EMBO Young Investigators! They are joining an international network of more than 800 life scientists – Welcome!
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Read the press release here:
https://www.embo.org/press-releases/twenty-eight-group-leaders-become-embo-young-investigators/
Reposted by Alejo Rodriguez-Fraticelli
The November Issue of #ExpHem is here! Explore the lineup, including Honoring giants in hematopoietic and progenitor cell biology www.exphem.org/article/S030...
November 19, 2025 at 10:15 PM
The November Issue of #ExpHem is here! Explore the lineup, including Honoring giants in hematopoietic and progenitor cell biology www.exphem.org/article/S030...
Reposted by Alejo Rodriguez-Fraticelli
Our lab website just got a major refresh to better present:
Our research philosophy: why chromatin is central to our work.
A snapshot of our culture: diverse, collaborative, impact-driven.
Our priorities: how we translate discoveries into clinical reality.
Check it out
Our research philosophy: why chromatin is central to our work.
A snapshot of our culture: diverse, collaborative, impact-driven.
Our priorities: how we translate discoveries into clinical reality.
Check it out
Lupien Lab
lupienlab.uhnresearch.ca
November 27, 2025 at 10:42 PM
Our lab website just got a major refresh to better present:
Our research philosophy: why chromatin is central to our work.
A snapshot of our culture: diverse, collaborative, impact-driven.
Our priorities: how we translate discoveries into clinical reality.
Check it out
Our research philosophy: why chromatin is central to our work.
A snapshot of our culture: diverse, collaborative, impact-driven.
Our priorities: how we translate discoveries into clinical reality.
Check it out
Reposted by Alejo Rodriguez-Fraticelli
Emergence and Self-organisation across biological scales! I hope you are ready for next year conference! It will be an incredible event April 20-22 2026. The first of many #LakeConference organised by
@ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org
@ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org
#CellBio community, this one is for you! Applications are open for the #LakeConference on Modeling Life from Cells to Tissues – co-hosted with Circuit Neuroscience Basel!
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
📆 April 20-22, 2026
📍 Seattle, USA
🔬 All career stages welcomed.
Apply to attend by 12/12: alleninstitute.org/events/aics-...
2026 Lake Conference
Join the Allen Institute for Cell Science and Circuit Neuroscience Basel in Seattle, Washington, April 20–22, 2026, for a 3 day conference, Modeling...
alleninstitute.org
November 26, 2025 at 10:58 AM
Emergence and Self-organisation across biological scales! I hope you are ready for next year conference! It will be an incredible event April 20-22 2026. The first of many #LakeConference organised by
@ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org
@ehannezo.bsky.social @alleninstitute.org and James Sharpe @embl.org
Outstanding PhD fellowship call OPEN for excellent students.
lacaixafoundation.org/en/doctoral-...
This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels).
If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!
lacaixafoundation.org/en/doctoral-...
This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels).
If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!
Doctoral INPhINIT fellowships - Incoming Call 2026
We grant 30 fellowships for researchers of any nationality who wish to pursue a doctorate in a STEM discipline at research centres of excellence in Spain or Portugal.
www.google.com
November 26, 2025 at 7:43 AM
Outstanding PhD fellowship call OPEN for excellent students.
lacaixafoundation.org/en/doctoral-...
This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels).
If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!
lacaixafoundation.org/en/doctoral-...
This is for students incoming from outside Spain. And it is VERY well supported (ie at European levels).
If you’re interested in doing a PhD in our lab @irbbarcelona.org, reach out!!!!
I didn’t get to meet the legend of Garcia Bellido as a PhD student at the “Severo Ochoa” as he was already half retiring… but even then, his presence in the department was all encompassing… My condolences to the family of scientists that he mentored. What a giant - we’ll always be in his debt.
November 17, 2025 at 8:15 AM
I didn’t get to meet the legend of Garcia Bellido as a PhD student at the “Severo Ochoa” as he was already half retiring… but even then, his presence in the department was all encompassing… My condolences to the family of scientists that he mentored. What a giant - we’ll always be in his debt.