FEBS Letters
@febsletters.bsky.social
Publishing cutting-edge reports in Biochemistry, Structural Biology, Molecular Cell Biology, Biophysics, Systems Biology, Microbiology and more. Part of @febspress.bsky.social. febsletters.org
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🍂 Our November issue is here!
🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest
Find the whole issue, featuring research articles on #neuroscience and #cancer, here:
➡️ bit.ly/3JGZG9q
🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest
Find the whole issue, featuring research articles on #neuroscience and #cancer, here:
➡️ bit.ly/3JGZG9q
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!
#EESOrgan
@events.embl.org
#EESOrgan
@events.embl.org
November 13, 2025 at 12:17 PM
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!
#EESOrgan
@events.embl.org
#EESOrgan
@events.embl.org
“Influencing science and influencing scientists are two distinct, and distinctly difficult, achievements. Professor Jean H. Langenheim accomplished both.” 🌿
🏆 FEBS Letters presents an essay by Rayane da Cruz Albino, winner of our #WomenInScience Writing Contest:
➡️ doi.org/10.1002/1873-3468.70197
🏆 FEBS Letters presents an essay by Rayane da Cruz Albino, winner of our #WomenInScience Writing Contest:
➡️ doi.org/10.1002/1873-3468.70197
November 11, 2025 at 12:02 PM
“Influencing science and influencing scientists are two distinct, and distinctly difficult, achievements. Professor Jean H. Langenheim accomplished both.” 🌿
🏆 FEBS Letters presents an essay by Rayane da Cruz Albino, winner of our #WomenInScience Writing Contest:
➡️ doi.org/10.1002/1873-3468.70197
🏆 FEBS Letters presents an essay by Rayane da Cruz Albino, winner of our #WomenInScience Writing Contest:
➡️ doi.org/10.1002/1873-3468.70197
Reposted by FEBS Letters
Saygin’s new ALS paper — showing nucleoporin alterations — just made the journal front cover @febsletters.bsky.social febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Cover illustration Stress granules in iPSCs treated with arsenite (G3BP1 (green) / NUP107 (red) / Hoechst (nucleus)). Image credit: Saygin Bilican. The image refers to Bilican et al., “C9orf72 ALS-ca....
febs.onlinelibrary.wiley.com
November 10, 2025 at 7:29 PM
Saygin’s new ALS paper — showing nucleoporin alterations — just made the journal front cover @febsletters.bsky.social febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by FEBS Letters
🚨Exciting news: A recent study from our #FOR5762 member @thevilchezlab.bsky.social has been selected for the cover of @febsletters.bsky.social!
Huge congrats to @thevilchezlab.bsky.social, Saygın Bilican and all co-authors for this fantastic highlight on #ALS-linked #Nup107 mislocalization! 🎉
Huge congrats to @thevilchezlab.bsky.social, Saygın Bilican and all co-authors for this fantastic highlight on #ALS-linked #Nup107 mislocalization! 🎉
Saygin’s new ALS paper — showing nucleoporin alterations — just made the journal front cover @febsletters.bsky.social febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Cover illustration Stress granules in iPSCs treated with arsenite (G3BP1 (green) / NUP107 (red) / Hoechst (nucleus)). Image credit: Saygin Bilican. The image refers to Bilican et al., “C9orf72 ALS-ca....
febs.onlinelibrary.wiley.com
November 11, 2025 at 8:00 AM
🚨Exciting news: A recent study from our #FOR5762 member @thevilchezlab.bsky.social has been selected for the cover of @febsletters.bsky.social!
Huge congrats to @thevilchezlab.bsky.social, Saygın Bilican and all co-authors for this fantastic highlight on #ALS-linked #Nup107 mislocalization! 🎉
Huge congrats to @thevilchezlab.bsky.social, Saygın Bilican and all co-authors for this fantastic highlight on #ALS-linked #Nup107 mislocalization! 🎉
🍂 Our November issue is here!
🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest
Find the whole issue, featuring research articles on #neuroscience and #cancer, here:
➡️ bit.ly/3JGZG9q
🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest
Find the whole issue, featuring research articles on #neuroscience and #cancer, here:
➡️ bit.ly/3JGZG9q
November 10, 2025 at 7:11 PM
🍂 Our November issue is here!
🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest
Find the whole issue, featuring research articles on #neuroscience and #cancer, here:
➡️ bit.ly/3JGZG9q
🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest
Find the whole issue, featuring research articles on #neuroscience and #cancer, here:
➡️ bit.ly/3JGZG9q
Tropomodulin-1 caps the slow-growing ends of #actin filaments, controlling their length and stability to maintain cellular architecture. Discover how TMOD1 is emerging as a multifunctional protein connecting cytoskeletal dynamics to disease and #DrugDiscovery here:
➡️ doi.org/10.1002/1873-3468.70176
➡️ doi.org/10.1002/1873-3468.70176
November 6, 2025 at 12:02 PM
Tropomodulin-1 caps the slow-growing ends of #actin filaments, controlling their length and stability to maintain cellular architecture. Discover how TMOD1 is emerging as a multifunctional protein connecting cytoskeletal dynamics to disease and #DrugDiscovery here:
➡️ doi.org/10.1002/1873-3468.70176
➡️ doi.org/10.1002/1873-3468.70176
The TOR pathway is a master regulator of cell growth and #metabolism. Here, Robbie Loewith and Lucas Tafur revisit the #StructuralBiology of TOR Complexes 1 and 2, highlighting how lipid #membranes serve as platforms for their activation and regulation.
➡️ doi.org/10.1002/1873-3468.70171
➡️ doi.org/10.1002/1873-3468.70171
November 4, 2025 at 12:01 PM
The TOR pathway is a master regulator of cell growth and #metabolism. Here, Robbie Loewith and Lucas Tafur revisit the #StructuralBiology of TOR Complexes 1 and 2, highlighting how lipid #membranes serve as platforms for their activation and regulation.
➡️ doi.org/10.1002/1873-3468.70171
➡️ doi.org/10.1002/1873-3468.70171
🦠 Enteropathogenic #Ecoli (#EPEC) attaches to host intestinal epithelial cells. Compared to HeLa cells, jejunal #organoid-derived monolayers show lower bacterial attachment, less epithelial cell death and delayed inflammatory response:
➡️ doi.org/10.1002/1873-3468.70182
➡️ doi.org/10.1002/1873-3468.70182
October 31, 2025 at 12:02 PM
🦠 Enteropathogenic #Ecoli (#EPEC) attaches to host intestinal epithelial cells. Compared to HeLa cells, jejunal #organoid-derived monolayers show lower bacterial attachment, less epithelial cell death and delayed inflammatory response:
➡️ doi.org/10.1002/1873-3468.70182
➡️ doi.org/10.1002/1873-3468.70182
🔔 Special Issue: Biology of B-cell malignancies
Seven Reviews focusing on conceptual and technological advancements in our understanding of B-cell neoplasms illustrate how they secure survival and evade therapy ➡️ bit.ly/48UhckL
👩🔬 Guest-edited by Patricia Pérez-Galán & Martina Seiffert
Seven Reviews focusing on conceptual and technological advancements in our understanding of B-cell neoplasms illustrate how they secure survival and evade therapy ➡️ bit.ly/48UhckL
👩🔬 Guest-edited by Patricia Pérez-Galán & Martina Seiffert
October 30, 2025 at 5:05 PM
🔔 Special Issue: Biology of B-cell malignancies
Seven Reviews focusing on conceptual and technological advancements in our understanding of B-cell neoplasms illustrate how they secure survival and evade therapy ➡️ bit.ly/48UhckL
👩🔬 Guest-edited by Patricia Pérez-Galán & Martina Seiffert
Seven Reviews focusing on conceptual and technological advancements in our understanding of B-cell neoplasms illustrate how they secure survival and evade therapy ➡️ bit.ly/48UhckL
👩🔬 Guest-edited by Patricia Pérez-Galán & Martina Seiffert
🎉🎖️Congratulations to 🌟Gabriel Péréz-Lara🌟 (UNAB, Santiago, Chile), winner of the FEBS Letters #PosterPrize at #MBioSys25, held in Puerto Varas, Chile! 🎉👏👏👏🎊
@molbiosystems.bsky.social
@molbiosystems.bsky.social
October 30, 2025 at 1:24 PM
🎉🎖️Congratulations to 🌟Gabriel Péréz-Lara🌟 (UNAB, Santiago, Chile), winner of the FEBS Letters #PosterPrize at #MBioSys25, held in Puerto Varas, Chile! 🎉👏👏👏🎊
@molbiosystems.bsky.social
@molbiosystems.bsky.social
🎉🎖️We congratulate 🌟Francesca Cervellini 🌟 @tigem.bsky.social on winning the FEBS Letters #PosterPrize at the #EMBO Workshop on #LipidDroplets, held in Sant Feliu de Guíxols, Spain! 🎉👏👏👏
#EMBOlipidDroplets
#EMBOlipidDroplets
October 30, 2025 at 1:14 PM
🎉🎖️We congratulate 🌟Francesca Cervellini 🌟 @tigem.bsky.social on winning the FEBS Letters #PosterPrize at the #EMBO Workshop on #LipidDroplets, held in Sant Feliu de Guíxols, Spain! 🎉👏👏👏
#EMBOlipidDroplets
#EMBOlipidDroplets
#CryoEM can now deliver atomic-resolution structures, but their value depends on the quality of their models.
This review highlights how combining traditional model-building with physics-based methods can shape the future of structural biology:
➡️ doi.org/10.1002/1873-3468.70165
This review highlights how combining traditional model-building with physics-based methods can shape the future of structural biology:
➡️ doi.org/10.1002/1873-3468.70165
October 29, 2025 at 12:04 PM
#CryoEM can now deliver atomic-resolution structures, but their value depends on the quality of their models.
This review highlights how combining traditional model-building with physics-based methods can shape the future of structural biology:
➡️ doi.org/10.1002/1873-3468.70165
This review highlights how combining traditional model-building with physics-based methods can shape the future of structural biology:
➡️ doi.org/10.1002/1873-3468.70165
Mice and pigs have taught us a lot about immunity, but #zebrafish models remain underused in this field. 🐟
Learn more about how recent advances on understudied gut #immune cells in zebrafish are helping us uncover immune mechanisms across vertebrates:
➡️ doi.org/10.1002/1873-3468.70161
Learn more about how recent advances on understudied gut #immune cells in zebrafish are helping us uncover immune mechanisms across vertebrates:
➡️ doi.org/10.1002/1873-3468.70161
October 27, 2025 at 12:04 PM
Mice and pigs have taught us a lot about immunity, but #zebrafish models remain underused in this field. 🐟
Learn more about how recent advances on understudied gut #immune cells in zebrafish are helping us uncover immune mechanisms across vertebrates:
➡️ doi.org/10.1002/1873-3468.70161
Learn more about how recent advances on understudied gut #immune cells in zebrafish are helping us uncover immune mechanisms across vertebrates:
➡️ doi.org/10.1002/1873-3468.70161
🌍 “Together we can!”
Our latest #PatientAdvocacy interview is with the #MarfanEuropeNetwork, an organization of 14 national #MarfanSyndrome patient groups. Learn how they bring communities together here:
➡️ doi.org/10.1002/1873-3468.70183
Our latest #PatientAdvocacy interview is with the #MarfanEuropeNetwork, an organization of 14 national #MarfanSyndrome patient groups. Learn how they bring communities together here:
➡️ doi.org/10.1002/1873-3468.70183
October 24, 2025 at 11:03 AM
🌍 “Together we can!”
Our latest #PatientAdvocacy interview is with the #MarfanEuropeNetwork, an organization of 14 national #MarfanSyndrome patient groups. Learn how they bring communities together here:
➡️ doi.org/10.1002/1873-3468.70183
Our latest #PatientAdvocacy interview is with the #MarfanEuropeNetwork, an organization of 14 national #MarfanSyndrome patient groups. Learn how they bring communities together here:
➡️ doi.org/10.1002/1873-3468.70183
🧬 Central to pseudouridylation of cellular #RNAs is dyskerin, a pseudouridine synthase with two known isoforms.
While the nuclear isoform is well studied, the cytoplasmic one is less explored. Here, Angrisani and Furia propose a model for its potential roles:
➡️ doi.org/10.1002/1873-3468.70154
While the nuclear isoform is well studied, the cytoplasmic one is less explored. Here, Angrisani and Furia propose a model for its potential roles:
➡️ doi.org/10.1002/1873-3468.70154
October 22, 2025 at 11:03 AM
🧬 Central to pseudouridylation of cellular #RNAs is dyskerin, a pseudouridine synthase with two known isoforms.
While the nuclear isoform is well studied, the cytoplasmic one is less explored. Here, Angrisani and Furia propose a model for its potential roles:
➡️ doi.org/10.1002/1873-3468.70154
While the nuclear isoform is well studied, the cytoplasmic one is less explored. Here, Angrisani and Furia propose a model for its potential roles:
➡️ doi.org/10.1002/1873-3468.70154
We're hiring for an Editorial Assistant!
📅 Deadline: 15 November 2025
📩 Send your CV and cover letter explaining your interest in the role to Daniela Ruffell: ruffell@febs.org
Find the full job description here ➡️ www.febs.org/news/jobs-po...
📅 Deadline: 15 November 2025
📩 Send your CV and cover letter explaining your interest in the role to Daniela Ruffell: ruffell@febs.org
Find the full job description here ➡️ www.febs.org/news/jobs-po...
October 21, 2025 at 12:14 PM
We're hiring for an Editorial Assistant!
📅 Deadline: 15 November 2025
📩 Send your CV and cover letter explaining your interest in the role to Daniela Ruffell: ruffell@febs.org
Find the full job description here ➡️ www.febs.org/news/jobs-po...
📅 Deadline: 15 November 2025
📩 Send your CV and cover letter explaining your interest in the role to Daniela Ruffell: ruffell@febs.org
Find the full job description here ➡️ www.febs.org/news/jobs-po...
👩🔬 In the UK, women represent just 26.7% of the #STEM workforce. For FEBS Letters, Dr. Laura Norton discusses the need for positive action.
Demand for STEM workers keeps growing and there is still a long way to go before we achieve true equity.
➡️ doi.org/10.1002/1873-3468.70178
#WomenInScience
Demand for STEM workers keeps growing and there is still a long way to go before we achieve true equity.
➡️ doi.org/10.1002/1873-3468.70178
#WomenInScience
October 20, 2025 at 11:02 AM
👩🔬 In the UK, women represent just 26.7% of the #STEM workforce. For FEBS Letters, Dr. Laura Norton discusses the need for positive action.
Demand for STEM workers keeps growing and there is still a long way to go before we achieve true equity.
➡️ doi.org/10.1002/1873-3468.70178
#WomenInScience
Demand for STEM workers keeps growing and there is still a long way to go before we achieve true equity.
➡️ doi.org/10.1002/1873-3468.70178
#WomenInScience
🔔 Our new issue features perspectives on the origins of life & #amyloid, and research on #StructuralBiology & #ProteinChemistry:
🌍 #AmyloidWorld hypothesis of the #OriginOfLife
🧬 Emergence of #evolution in the #RNA world
🧑🔬 Scientists' Forum: Cultivating female talent in science
➡️ bit.ly/4ojAbcM
🌍 #AmyloidWorld hypothesis of the #OriginOfLife
🧬 Emergence of #evolution in the #RNA world
🧑🔬 Scientists' Forum: Cultivating female talent in science
➡️ bit.ly/4ojAbcM
October 17, 2025 at 12:05 PM
🔔 Our new issue features perspectives on the origins of life & #amyloid, and research on #StructuralBiology & #ProteinChemistry:
🌍 #AmyloidWorld hypothesis of the #OriginOfLife
🧬 Emergence of #evolution in the #RNA world
🧑🔬 Scientists' Forum: Cultivating female talent in science
➡️ bit.ly/4ojAbcM
🌍 #AmyloidWorld hypothesis of the #OriginOfLife
🧬 Emergence of #evolution in the #RNA world
🧑🔬 Scientists' Forum: Cultivating female talent in science
➡️ bit.ly/4ojAbcM
🔄 Circulating endothelial cells are released into the bloodstream during tissue turnover or vascular injury.
Read on to learn how CECs can provide insights into prevention and treatment of #cancer, #brain pathologies, and #ageing-related disorders:
➡️ doi.org/10.1002/1873-3468.70149
Read on to learn how CECs can provide insights into prevention and treatment of #cancer, #brain pathologies, and #ageing-related disorders:
➡️ doi.org/10.1002/1873-3468.70149
October 17, 2025 at 11:04 AM
🔄 Circulating endothelial cells are released into the bloodstream during tissue turnover or vascular injury.
Read on to learn how CECs can provide insights into prevention and treatment of #cancer, #brain pathologies, and #ageing-related disorders:
➡️ doi.org/10.1002/1873-3468.70149
Read on to learn how CECs can provide insights into prevention and treatment of #cancer, #brain pathologies, and #ageing-related disorders:
➡️ doi.org/10.1002/1873-3468.70149
👩🔬🌐 How can we help #WomenInScience with their specific challenges? Cristina Goméz-Navarro set up a female #mentorship program in Madrid with clear objectives, events, and tips for others.
➡️ doi.org/10.1002/1873-3468.70170
➡️ doi.org/10.1002/1873-3468.70170
October 15, 2025 at 11:02 AM
👩🔬🌐 How can we help #WomenInScience with their specific challenges? Cristina Goméz-Navarro set up a female #mentorship program in Madrid with clear objectives, events, and tips for others.
➡️ doi.org/10.1002/1873-3468.70170
➡️ doi.org/10.1002/1873-3468.70170
#Amyotrophiclateralsclerosis (#ALS) can be caused by repeat expansions in C9orf72. A new study by David Vilchez et al. shows G3BP1 exhibits enhanced interaction with Nup107 in #motorneurons derived from patient iPSCs with C9orf72 mutations. @thevilchezlab.bsky.social
➡️https://tinyurl.com/zm2ujupc
➡️https://tinyurl.com/zm2ujupc
October 9, 2025 at 2:01 PM
#Amyotrophiclateralsclerosis (#ALS) can be caused by repeat expansions in C9orf72. A new study by David Vilchez et al. shows G3BP1 exhibits enhanced interaction with Nup107 in #motorneurons derived from patient iPSCs with C9orf72 mutations. @thevilchezlab.bsky.social
➡️https://tinyurl.com/zm2ujupc
➡️https://tinyurl.com/zm2ujupc
🎉Congratulations to 🌟Selin Pekel🌟 (Leiden University Medical Center, the Netherlands), winner of the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium ‘The human #microbiome’, held in Heidelberg, Germany! 🎉👏👏👏🎊
#EESMicrobiome
@events.embl.org
@selinpekel.bsky.social
@zellerlab.bsky.social
#EESMicrobiome
@events.embl.org
@selinpekel.bsky.social
@zellerlab.bsky.social
October 9, 2025 at 1:19 PM
🎉Congratulations to 🌟Selin Pekel🌟 (Leiden University Medical Center, the Netherlands), winner of the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium ‘The human #microbiome’, held in Heidelberg, Germany! 🎉👏👏👏🎊
#EESMicrobiome
@events.embl.org
@selinpekel.bsky.social
@zellerlab.bsky.social
#EESMicrobiome
@events.embl.org
@selinpekel.bsky.social
@zellerlab.bsky.social
Reposted by FEBS Letters
Awards were also given for poster presentations.
The Runner Up Poster Award, sponsored by
@natrevgenet.nature.com, went to Mélanie Lemaire (Université de Montréal, Canada), while the Best Talk Award, sponsored by @febsletters.bsky.social, went to Gabriel Pérez-Lara (UNAB, Chile).
The Runner Up Poster Award, sponsored by
@natrevgenet.nature.com, went to Mélanie Lemaire (Université de Montréal, Canada), while the Best Talk Award, sponsored by @febsletters.bsky.social, went to Gabriel Pérez-Lara (UNAB, Chile).
October 8, 2025 at 3:53 PM
Awards were also given for poster presentations.
The Runner Up Poster Award, sponsored by
@natrevgenet.nature.com, went to Mélanie Lemaire (Université de Montréal, Canada), while the Best Talk Award, sponsored by @febsletters.bsky.social, went to Gabriel Pérez-Lara (UNAB, Chile).
The Runner Up Poster Award, sponsored by
@natrevgenet.nature.com, went to Mélanie Lemaire (Université de Montréal, Canada), while the Best Talk Award, sponsored by @febsletters.bsky.social, went to Gabriel Pérez-Lara (UNAB, Chile).
🏅We congratulate 🌟Nils Bertram🌟 @lmumuenchen.bsky.social, on winning a FEBS Letters #PosterPrize at the #EMBOFEBSproteostasis meeting, held in Espoo, Finland! 🎉👏👏👏
📸 Photo: Nils with our Managing Editor, Dr. Duncan Wright
📸 Photo: Nils with our Managing Editor, Dr. Duncan Wright
October 9, 2025 at 1:01 PM
🏅We congratulate 🌟Nils Bertram🌟 @lmumuenchen.bsky.social, on winning a FEBS Letters #PosterPrize at the #EMBOFEBSproteostasis meeting, held in Espoo, Finland! 🎉👏👏👏
📸 Photo: Nils with our Managing Editor, Dr. Duncan Wright
📸 Photo: Nils with our Managing Editor, Dr. Duncan Wright
From lactation to malignancy: a new study by Pietro Ancona et al. reveals new insights into #breastcancer through comparison of healthy and cancerous breast gland at single-cell resolution.
Read the full article here ➡️ tinyurl.com/bdcd4c7v
Read the full article here ➡️ tinyurl.com/bdcd4c7v
October 6, 2025 at 12:58 PM
From lactation to malignancy: a new study by Pietro Ancona et al. reveals new insights into #breastcancer through comparison of healthy and cancerous breast gland at single-cell resolution.
Read the full article here ➡️ tinyurl.com/bdcd4c7v
Read the full article here ➡️ tinyurl.com/bdcd4c7v