Markus Elsner
@markuselsner.bsky.social
Deputy Director of the Institute for Intelligent Biotechnologies at HelmholtzMunich, former editor @naturebiotech.bsky.social, all views expressed here are my own
As every year, I am posting the best 5 books I read this year. #booksky
Today, #1:
Patrick Radden Keefe
Empire of Pain
www.goodreads.com/book/show/43...
One of the most interesting books I have read in a very long while.
Today, #1:
Patrick Radden Keefe
Empire of Pain
www.goodreads.com/book/show/43...
One of the most interesting books I have read in a very long while.
Goodreads
Discover and share books you love on Goodreads.
www.goodreads.com
December 30, 2025 at 9:02 PM
As every year, I am posting the best 5 books I read this year. #booksky
Today, #1:
Patrick Radden Keefe
Empire of Pain
www.goodreads.com/book/show/43...
One of the most interesting books I have read in a very long while.
Today, #1:
Patrick Radden Keefe
Empire of Pain
www.goodreads.com/book/show/43...
One of the most interesting books I have read in a very long while.
As every year, I am posting the best 5 books I read this year. #booksky
Today, #2:
Stephen Fry
Troy
www.goodreads.com/book/show/53...
Today, #2:
Stephen Fry
Troy
www.goodreads.com/book/show/53...
Troy (Stephen Fry's Great Mythology, #3)
في هذا العمل البديع، يعيد ستيفن فراي -بأسلوبه الأخَّاذ،…
www.goodreads.com
December 29, 2025 at 8:56 PM
As every year, I am posting the best 5 books I read this year. #booksky
Today, #2:
Stephen Fry
Troy
www.goodreads.com/book/show/53...
Today, #2:
Stephen Fry
Troy
www.goodreads.com/book/show/53...
This is going to be fun! I promise!
My team at Deep Piction (Munich) is hiring a Senior Director, Drug Discovery (Long Covid) to build and lead our early discovery engine. If you have 10+ years in early-stage biotech/pharma, let’s talk.
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Deep Piction hiring Senior Director Drug Discovery in Greater Munich Metropolitan Area | LinkedIn
Posted 10:31:52 AM. Senior Director, Drug Discovery (Long Covid)Location: Munich, Germany (Onsite)Type:…See this and similar jobs on LinkedIn.
www.linkedin.com
December 29, 2025 at 8:51 PM
This is going to be fun! I promise!
Reposted by Markus Elsner
Reviews/Perspectives Top #Citations 2025: 🥉🧪
M Van Hul, P Cani @microbesity.bsky.social (UC Louvain) et al.
The gut microbiome and cancer: from tumorigenesis to therapy
M Van Hul, P Cani @microbesity.bsky.social (UC Louvain) et al.
The gut microbiome and cancer: from tumorigenesis to therapy
The gut microbiome and cancer: from tumorigenesis to therapy - Nature Metabolism
This Review discusses the impact of the gut microbiota on cancer and on cancer therapy, highlighting the importance of developing microbiota-targeting strategies to improve cancer therapy outcomes
www.nature.com
December 29, 2025 at 6:01 PM
Reviews/Perspectives Top #Citations 2025: 🥉🧪
M Van Hul, P Cani @microbesity.bsky.social (UC Louvain) et al.
The gut microbiome and cancer: from tumorigenesis to therapy
M Van Hul, P Cani @microbesity.bsky.social (UC Louvain) et al.
The gut microbiome and cancer: from tumorigenesis to therapy
Like the Switch 2 so far, but @nintendousa.bsky.social made the transfer of system settings, saved games etc stupidly complicated (or even impossible after you dared to first try out)
December 29, 2025 at 2:28 PM
Like the Switch 2 so far, but @nintendousa.bsky.social made the transfer of system settings, saved games etc stupidly complicated (or even impossible after you dared to first try out)
Reposted by Markus Elsner
Robert F. Kennedy Jr. has stated that the 1918 flu pandemic was caused by a lab virus from vaccine research, a defective influenza vaccine. Let’s analyze what a lie this is. First, in 1918, 107 years ago, virology was in its infancy
December 27, 2025 at 11:42 PM
Robert F. Kennedy Jr. has stated that the 1918 flu pandemic was caused by a lab virus from vaccine research, a defective influenza vaccine. Let’s analyze what a lie this is. First, in 1918, 107 years ago, virology was in its infancy
Markus Elsner
@markuselsner.bsky.social
· 21h
As every year, I am posting the best 5 books I read this year. #booksky
Today, #3:
Robert Harris
Fatherland
www.goodreads.com/book/show/56...
Have had this on my reading list for decades. Finally read it and was not disappointed.
@markuselsner.bsky.social
· 21h
As every year, I am posting the best 5 books I read this year. #booksky
Today, #3:
Robert Harris
Fatherland
www.goodreads.com/book/show/56...
Have had this on my reading list for decades. Finally read it and was not disappointed.
Fatherland
April 1964. The naked body of an old man floats in a l…
www.goodreads.com
December 28, 2025 at 4:00 PM
Markus Elsner
@markuselsner.bsky.social
· 21h
As every year, I am posting the best 5 books I read this year. #booksky
Today, #3:
Robert Harris
Fatherland
www.goodreads.com/book/show/56...
Have had this on my reading list for decades. Finally read it and was not disappointed.
@markuselsner.bsky.social
· 21h
As every year, I am posting the best 5 books I read this year. #booksky
Today, #3:
Robert Harris
Fatherland
www.goodreads.com/book/show/56...
Have had this on my reading list for decades. Finally read it and was not disappointed.
As every year, I am posting the best 5 books I read this year. #booksky
Today, #4:
Mary Beard
Emperor of Rome: Ruling the Ancient Roman World
www.goodreads.com/book/show/12...
Yours?
Today, #4:
Mary Beard
Emperor of Rome: Ruling the Ancient Roman World
www.goodreads.com/book/show/12...
Yours?
Emperor of Rome: Ruling the Ancient Roman World
A sweeping account of the social and political world of…
www.goodreads.com
December 27, 2025 at 6:01 PM
As every year, I am posting the best 5 books I read this year. #booksky
Today, #4:
Mary Beard
Emperor of Rome: Ruling the Ancient Roman World
www.goodreads.com/book/show/12...
Yours?
Today, #4:
Mary Beard
Emperor of Rome: Ruling the Ancient Roman World
www.goodreads.com/book/show/12...
Yours?
As every year, I am posting the best 5 books I read this year. #booksky
Today, #5:
Carissa Orlando
The September House
www.goodreads.com/book/show/64...
Yours?
Today, #5:
Carissa Orlando
The September House
www.goodreads.com/book/show/64...
Yours?
The September House
A woman is determined to stay in her dream home even af…
www.goodreads.com
December 26, 2025 at 9:48 PM
As every year, I am posting the best 5 books I read this year. #booksky
Today, #5:
Carissa Orlando
The September House
www.goodreads.com/book/show/64...
Yours?
Today, #5:
Carissa Orlando
The September House
www.goodreads.com/book/show/64...
Yours?
Reposted by Markus Elsner
I semi-vibe coded a frontend for all the protein folding tools I've been running. It runs on modal and has 5 different open-source algorithms: Chai1, Boltz2, AF2, Protenix(-mini).
Not 100% polished but hopefully of use to some use to people in the field!
github.com/hgbrian/fold...
Not 100% polished but hopefully of use to some use to people in the field!
github.com/hgbrian/fold...
GitHub - hgbrian/foldism: protein folding app running on modal
protein folding app running on modal. Contribute to hgbrian/foldism development by creating an account on GitHub.
github.com
December 26, 2025 at 4:33 PM
I semi-vibe coded a frontend for all the protein folding tools I've been running. It runs on modal and has 5 different open-source algorithms: Chai1, Boltz2, AF2, Protenix(-mini).
Not 100% polished but hopefully of use to some use to people in the field!
github.com/hgbrian/fold...
Not 100% polished but hopefully of use to some use to people in the field!
github.com/hgbrian/fold...
Reposted by Markus Elsner
We're hiring for multiple open rank positions in the broad areas of biochemistry, molecular biology, and computational biology. With the recruitment of a new chair our Departmental strengths now include nuclear architecture, genomics and ancient DNA.
jobs.sciencecareers.org/job/676677/b...
jobs.sciencecareers.org/job/676677/b...
Biology Faculty Opportunities (Open Rank) - Galveston, Texas job with University of Texas Medical Branch | 676677
The Department of Biochemistry and Molecular Biology at UTMB Health invites applications for multiple tenure-track positions at all ranks; assistant,
jobs.sciencecareers.org
December 23, 2025 at 8:47 PM
We're hiring for multiple open rank positions in the broad areas of biochemistry, molecular biology, and computational biology. With the recruitment of a new chair our Departmental strengths now include nuclear architecture, genomics and ancient DNA.
jobs.sciencecareers.org/job/676677/b...
jobs.sciencecareers.org/job/676677/b...
Reposted by Markus Elsner
📢🚨 PhD position in my new "@welgain.bsky.social" project 🚨 📢
I am looking for a 🎓 PhD student 🎓 interested in impact evaluation, welfare programs, labor & public economics, social policy & inequality, to work with me at NTNU in Trondheim (www.ntnu.edu). (1/3) 👇
I am looking for a 🎓 PhD student 🎓 interested in impact evaluation, welfare programs, labor & public economics, social policy & inequality, to work with me at NTNU in Trondheim (www.ntnu.edu). (1/3) 👇
Norwegian University of Science and Technology - NTNU
Norwegian University of Science and Technology. Located in Trondheim, Gjøvik and Ålesund. Specializing in technology and the natural sciences. 40 000 students.
www.ntnu.edu
December 23, 2025 at 6:37 PM
📢🚨 PhD position in my new "@welgain.bsky.social" project 🚨 📢
I am looking for a 🎓 PhD student 🎓 interested in impact evaluation, welfare programs, labor & public economics, social policy & inequality, to work with me at NTNU in Trondheim (www.ntnu.edu). (1/3) 👇
I am looking for a 🎓 PhD student 🎓 interested in impact evaluation, welfare programs, labor & public economics, social policy & inequality, to work with me at NTNU in Trondheim (www.ntnu.edu). (1/3) 👇
💯
Something very funny about de santis praising Coolidge for “immigration.” Coolidge’s immigration policy was that people named de santis shouldn’t be allowed to come here bsky.app/profile/anth...
There’s like a dozen things that are wrong about this statement.
December 23, 2025 at 12:56 PM
💯
Reposted by Markus Elsner
"To invest. how high-fat diets alter risk-taking behavior, we designed a conflict assay in which mice are tasked with foraging for food under natural predatory threat. While standard diet food intake decreases in the presence of a rat predator, mice continue to seek & consume HFD despite the threat"
High-fat food reinforces risk taking by suppressing defensive neurons
This study by de Araujo Salgado and Krashes reveals how high-fat diets suppress defensive
neural circuits, driving riskier foraging in the presence of predation. The findings
highlight how high-fat fo...
www.cell.com
December 23, 2025 at 8:44 AM
"To invest. how high-fat diets alter risk-taking behavior, we designed a conflict assay in which mice are tasked with foraging for food under natural predatory threat. While standard diet food intake decreases in the presence of a rat predator, mice continue to seek & consume HFD despite the threat"
Single cell transcriptomics from cleared tissue? Impossible you say? Check out our latest preprint!
Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess.
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
December 23, 2025 at 10:14 AM
Single cell transcriptomics from cleared tissue? Impossible you say? Check out our latest preprint!
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies go.nature.com/4gNLjeC
rdcu.be/eUK6B
rdcu.be/eUK6B
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
go.nature.com
December 23, 2025 at 10:12 AM
Reposted by Markus Elsner
Out today in @cp-cell.bsky.social! We studied how environmental stresses like high-fat diets today can prime tumorigenesis months to years in the future (1/n)
December 22, 2025 at 4:35 PM
Out today in @cp-cell.bsky.social! We studied how environmental stresses like high-fat diets today can prime tumorigenesis months to years in the future (1/n)
Reposted by Markus Elsner
⏳ Last call for researchers! Submit your short talk or scholarship app by Dec 23 for the Keystone Symposium on Solute Carrier Transporters. See cutting-edge SLC biology this April in Beverly, MA! 👉 hubs.la/Q03YKWsn0
@giuliosupertifurga.bsky.social
#SoluteCarriers #SLCtransporters #KeystoneSymposia
@giuliosupertifurga.bsky.social
#SoluteCarriers #SLCtransporters #KeystoneSymposia
December 19, 2025 at 7:52 PM
⏳ Last call for researchers! Submit your short talk or scholarship app by Dec 23 for the Keystone Symposium on Solute Carrier Transporters. See cutting-edge SLC biology this April in Beverly, MA! 👉 hubs.la/Q03YKWsn0
@giuliosupertifurga.bsky.social
#SoluteCarriers #SLCtransporters #KeystoneSymposia
@giuliosupertifurga.bsky.social
#SoluteCarriers #SLCtransporters #KeystoneSymposia
Reposted by Markus Elsner
Ich bin ja tolerant, aber diese Wokeness muss auch mal ein Ende haben. Jetzt feiern manche Leute ernsthaft ein Fest, bei dem so ein Unterschichtkind der Star ist, das in einem Stall geboren wird, von einer unverheirateten Frau, man kennt das ja, die Familienverhältnisse bei solchen Leuten.
December 22, 2025 at 10:18 AM
Ich bin ja tolerant, aber diese Wokeness muss auch mal ein Ende haben. Jetzt feiern manche Leute ernsthaft ein Fest, bei dem so ein Unterschichtkind der Star ist, das in einem Stall geboren wird, von einer unverheirateten Frau, man kennt das ja, die Familienverhältnisse bei solchen Leuten.
Reposted by Markus Elsner
Wow, exciting convergence of chem bio technologies in this paper! 🤯
Now online! Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Mapping cellular targets of covalent cancer drugs in the entire mammalian body
vCATCH is a volumetric tissue labeling technique enabling cellular-resolution mapping of covalent drug targets throughout the entire mammalian body.
dlvr.it
December 22, 2025 at 4:27 PM
Wow, exciting convergence of chem bio technologies in this paper! 🤯
Reposted by Markus Elsner
Das kleinste Säugetier der Welt, die Estruskerspitzmaus, wiegt ausgewachsen 1,8 Gramm.
December 21, 2025 at 5:41 PM
Das kleinste Säugetier der Welt, die Estruskerspitzmaus, wiegt ausgewachsen 1,8 Gramm.
Re-watching all Stranger Things episodes before starting the final season.
Such a great show!
Such a great show!
December 21, 2025 at 7:56 PM
Re-watching all Stranger Things episodes before starting the final season.
Such a great show!
Such a great show!
Interesting! But could the immune system stop being so damn complicated, please ...
Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8
Online now: Opposing functions of distinct regulatory T cell subsets in colorectal cancer
December 21, 2025 at 4:55 PM
Interesting! But could the immune system stop being so damn complicated, please ...
Reposted by Markus Elsner
Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8
Online now: Opposing functions of distinct regulatory T cell subsets in colorectal cancer
Opposing functions of distinct regulatory T cell subsets in colorectal cancer
Huang et al. study the heterogeneity of regulatory T (Treg) cells in a genetic model of colorectal cancer (CRC) and find that interleukin (IL)-10− Treg cells promote tumor progression, whereas IL-10+ Treg cells restrain tumor growth by suppressing IL-17 production from CD4+ T cells. This functional dichotomy between Treg subsets is seen in human CRC and may be relevant in other barrier tissue cancers.
dlvr.it
December 15, 2025 at 9:34 PM
Excited to share our new study, the paper is out today @cp-immunity.bsky.social! Not all Treg cells are the same. We identified two Treg cell subsets with opposing functions in colorectal cancer (CRC). 1/8
Reposted by Markus Elsner
We are thrilled to invite you to the Michael Sars Symposium 2026 - Living systems in a variable ocean, together with our co-organizers at @cbubergen.bsky.social! Mark June 4, 2026 in your calendars, and watch out for our speaker lineup reveal in the new year 🙌
December 19, 2025 at 2:54 PM
We are thrilled to invite you to the Michael Sars Symposium 2026 - Living systems in a variable ocean, together with our co-organizers at @cbubergen.bsky.social! Mark June 4, 2026 in your calendars, and watch out for our speaker lineup reveal in the new year 🙌