Ali Maximilian Erturk
@erturklab.bsky.social
AI and tissue clearing-based technologies for health.
Director at Helmholtz Munich, Full professor at LMU Munich, and CEO of Deep Piction (@deeppiction.bsky.social)
We’re🇩🇪🇹🇷🇭🇷🇨🇳🇮🇹🇮🇳🇸🇮🇴🇲🇨🇱🇭🇺🇧🇬🇺🇦🇷🇴🇦🇹🇹🇼🏳🌈
Director at Helmholtz Munich, Full professor at LMU Munich, and CEO of Deep Piction (@deeppiction.bsky.social)
We’re🇩🇪🇹🇷🇭🇷🇨🇳🇮🇹🇮🇳🇸🇮🇴🇲🇨🇱🇭🇺🇧🇬🇺🇦🇷🇴🇦🇹🇹🇼🏳🌈
We’re hiring – Computer Science PhD at iBIO (Helmholtz Munich / LMU).
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Helmholtz Munich hiring PhD Position – Deep Learning for Multi-Omics Atlases of the Mammalian Body in Greater Munich Metropolitan Area | LinkedIn
Posted 8:43:27 PM. AI Scientist - PhD Position Institute for Intelligent Biotechnologies (iBIO), Helmholtz Munich /…See this and similar jobs on LinkedIn.
www.linkedin.com
January 13, 2026 at 8:51 PM
We’re hiring – Computer Science PhD at iBIO (Helmholtz Munich / LMU).
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Build AI-driven, whole-body multi-omics atlases by combining scRNA-seq, spatial transcriptomics, proteomics & 3D imaging.
Looking for strong omics data analysis skills with ML/DL.
Apply or share:
www.linkedin.com/jobs/view/43...
Reposted by Ali Maximilian Erturk
This is going to be fun! I promise!
My team at Deep Piction (Munich) is hiring a Senior Director, Drug Discovery (Long Covid) to build and lead our early discovery engine. If you have 10+ years in early-stage biotech/pharma, let’s talk.
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Deep Piction hiring Senior Director Drug Discovery in Greater Munich Metropolitan Area | LinkedIn
Posted 10:31:52 AM. Senior Director, Drug Discovery (Long Covid)Location: Munich, Germany (Onsite)Type:…See this and similar jobs on LinkedIn.
www.linkedin.com
December 29, 2025 at 8:51 PM
This is going to be fun! I promise!
My team at Deep Piction (Munich) is hiring a Senior Director, Drug Discovery (Long Covid) to build and lead our early discovery engine. If you have 10+ years in early-stage biotech/pharma, let’s talk.
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Deep Piction hiring Senior Director Drug Discovery in Greater Munich Metropolitan Area | LinkedIn
Posted 10:31:52 AM. Senior Director, Drug Discovery (Long Covid)Location: Munich, Germany (Onsite)Type:…See this and similar jobs on LinkedIn.
www.linkedin.com
December 29, 2025 at 6:44 PM
My team at Deep Piction (Munich) is hiring a Senior Director, Drug Discovery (Long Covid) to build and lead our early discovery engine. If you have 10+ years in early-stage biotech/pharma, let’s talk.
www.linkedin.com/jobs/view/43...
www.linkedin.com/jobs/view/43...
Reposted by Ali Maximilian Erturk
Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess.
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
December 18, 2025 at 2:46 PM
Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess.
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Reposted by Ali Maximilian Erturk
Single cell transcriptomics from cleared tissue? Impossible you say? Check out our latest preprint!
Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess.
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
December 23, 2025 at 10:14 AM
Single cell transcriptomics from cleared tissue? Impossible you say? Check out our latest preprint!
Reposted by Ali Maximilian Erturk
Very cool paper in NBT from the Dietz and Erturk labs @erturklab.bsky.social @markuselsner.bsky.social go.nature.com/4gNLjeC
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning - Nature Biotechnology
An integrated experimental and deep learning pipeline reveals cell-level targeting of nanocarriers in whole bodies.
go.nature.com
December 23, 2025 at 10:07 PM
Very cool paper in NBT from the Dietz and Erturk labs @erturklab.bsky.social @markuselsner.bsky.social go.nature.com/4gNLjeC
Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess.
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
December 18, 2025 at 2:46 PM
Most transcriptomics studies sample ~0.001% of a mouse. Which region do we choose? Often: we guess.
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Meet DISCO-seq 🤗 flipping the order: RNA-preserving clearing → whole-organ/whole-body 3D imaging → pick ROIs in 3D → unbiased scRNA-seq.
Preprint: www.biorxiv.org/content/10.6...
Congratulations to our scientist, Laurent Simons, for earning his PhD in quantum physics at just 15—an exceptional achievement.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
December 8, 2025 at 2:22 PM
Congratulations to our scientist, Laurent Simons, for earning his PhD in quantum physics at just 15—an exceptional achievement.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
In our lab, Laurent’s work focuses on in silico biology to accelerate treatment of devastating diseases. We’re thrilled to have him on the team.
Hiring: PostDoc in Tissue Clearing & 3D Histopathology 🧪🖥️
My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues.
More info: www.linkedin.com/posts/ali-ma...
My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues.
More info: www.linkedin.com/posts/ali-ma...
#histopathology #tissueclearing #lightsheetmicroscopy #postdoc #sciencecareers #munich | Ali Maximilian Ertürk
Hiring: PostDoc in Tissue Clearing & 3D Histopathology 🧪🖥️
My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues.
...
www.linkedin.com
December 6, 2025 at 4:08 PM
Hiring: PostDoc in Tissue Clearing & 3D Histopathology 🧪🖥️
My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues.
More info: www.linkedin.com/posts/ali-ma...
My lab at Helmholtz Munich is seeking a highly motivated PostDoc/Scientist to strengthen our efforts in advanced imaging of cancer tissues.
More info: www.linkedin.com/posts/ali-ma...
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
November 4, 2025 at 1:55 PM
We are introducing LipiGo 🤗
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. Precision delivery at the cell level isn't far! www.biorxiv.org/content/10.1...
Reposted by Ali Maximilian Erturk
New pre-print from our lab (@erturklab.bsky.social)
www.biorxiv.org/content/10.1...
Skeetorial to follow, but check it out now if you are interested in targeted drug delivery
www.biorxiv.org/content/10.1...
Skeetorial to follow, but check it out now if you are interested in targeted drug delivery
LipiGo: A Versatile DNA-Lipid Nanoparticle Hybrid for Precision Drug Delivery
Lipid nanoparticles (LNPs) are established carriers for nucleic acid delivery, however, achieving efficient delivery to non-hepatic tissues remains a major challenge. Here, we present LipiGo, a nanoca...
www.biorxiv.org
September 19, 2025 at 9:25 AM
New pre-print from our lab (@erturklab.bsky.social)
www.biorxiv.org/content/10.1...
Skeetorial to follow, but check it out now if you are interested in targeted drug delivery
www.biorxiv.org/content/10.1...
Skeetorial to follow, but check it out now if you are interested in targeted drug delivery
Your Brilliant Idea Won't Get You a PI Position
As scientists, we are passionate about our research and great ideas. But this is a dream that rarely gets you hired.
1/9
As scientists, we are passionate about our research and great ideas. But this is a dream that rarely gets you hired.
1/9
September 17, 2025 at 8:18 PM
Your Brilliant Idea Won't Get You a PI Position
As scientists, we are passionate about our research and great ideas. But this is a dream that rarely gets you hired.
1/9
As scientists, we are passionate about our research and great ideas. But this is a dream that rarely gets you hired.
1/9
We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies.
Kolabas…Ertürk, Cell (2023):
www.cell.com/cell/pdf/S00...
Our Tech: www.biorxiv.org/content/10.1...
bit.ly/3PQuymm
Kolabas…Ertürk, Cell (2023):
www.cell.com/cell/pdf/S00...
Our Tech: www.biorxiv.org/content/10.1...
bit.ly/3PQuymm
August 13, 2025 at 11:04 AM
We discovered that the skull bone marrow has direct connections to the brain surface & mirrors brain inflammation, making it a new site for diagnosing & monitoring brain pathologies.
Kolabas…Ertürk, Cell (2023):
www.cell.com/cell/pdf/S00...
Our Tech: www.biorxiv.org/content/10.1...
bit.ly/3PQuymm
Kolabas…Ertürk, Cell (2023):
www.cell.com/cell/pdf/S00...
Our Tech: www.biorxiv.org/content/10.1...
bit.ly/3PQuymm
We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by tissue, organ by organ, at the cellular level in 3D.
biorxiv.org/content/10.1...
biorxiv.org/content/10.1...
July 30, 2025 at 9:15 PM
We developed MouseMapper AI, a deep learning ensemble for the analysis of whole-body systems, including the nervous and immune systems, to map disease/drug perturbations tissue by tissue, organ by organ, at the cellular level in 3D.
biorxiv.org/content/10.1...
biorxiv.org/content/10.1...
Don’t Be Afraid to Use AI Tools: Learn How to Utilize Them to Drive Innovation
Many people are concerned about using AI tools in science. They say it hallucinates or that using it is cheating.
I disagree. I think these fears focus on the wrong thing and discourage many.
1/10
Many people are concerned about using AI tools in science. They say it hallucinates or that using it is cheating.
I disagree. I think these fears focus on the wrong thing and discourage many.
1/10
July 1, 2025 at 8:45 PM
Don’t Be Afraid to Use AI Tools: Learn How to Utilize Them to Drive Innovation
Many people are concerned about using AI tools in science. They say it hallucinates or that using it is cheating.
I disagree. I think these fears focus on the wrong thing and discourage many.
1/10
Many people are concerned about using AI tools in science. They say it hallucinates or that using it is cheating.
I disagree. I think these fears focus on the wrong thing and discourage many.
1/10
BIG NEWS:
As the CEO, I am thrilled to announce the closure of our seed financing round for Deep Piction.
👉🏻https://bit.ly/3TnFpXq
Our vision is to bring the fastest and most precise therapeutics to millions using our transparency and AI technology platform.
As the CEO, I am thrilled to announce the closure of our seed financing round for Deep Piction.
👉🏻https://bit.ly/3TnFpXq
Our vision is to bring the fastest and most precise therapeutics to millions using our transparency and AI technology platform.
June 12, 2025 at 8:15 PM
BIG NEWS:
As the CEO, I am thrilled to announce the closure of our seed financing round for Deep Piction.
👉🏻https://bit.ly/3TnFpXq
Our vision is to bring the fastest and most precise therapeutics to millions using our transparency and AI technology platform.
As the CEO, I am thrilled to announce the closure of our seed financing round for Deep Piction.
👉🏻https://bit.ly/3TnFpXq
Our vision is to bring the fastest and most precise therapeutics to millions using our transparency and AI technology platform.
Failure is Inevitable: How to Build a Resilient Lab Culture
In my last posts, I shared my experiences with building a team and focusing. When you look from the outside, you might see a story of quick, impactful papers and major grants.
But that’s only half the story.
1/11
In my last posts, I shared my experiences with building a team and focusing. When you look from the outside, you might see a story of quick, impactful papers and major grants.
But that’s only half the story.
1/11
June 11, 2025 at 2:31 PM
Failure is Inevitable: How to Build a Resilient Lab Culture
In my last posts, I shared my experiences with building a team and focusing. When you look from the outside, you might see a story of quick, impactful papers and major grants.
But that’s only half the story.
1/11
In my last posts, I shared my experiences with building a team and focusing. When you look from the outside, you might see a story of quick, impactful papers and major grants.
But that’s only half the story.
1/11
The importance of focusing on 1-2 projects as a starting PI.
Something that might sound crazy: when I finished my postdoc, I didn't have a job lined up. No position, no safety net.
As the academic job market is brutal, taking time off before securing my next position felt like career suicide.
1/10
Something that might sound crazy: when I finished my postdoc, I didn't have a job lined up. No position, no safety net.
As the academic job market is brutal, taking time off before securing my next position felt like career suicide.
1/10
June 9, 2025 at 4:15 PM
The importance of focusing on 1-2 projects as a starting PI.
Something that might sound crazy: when I finished my postdoc, I didn't have a job lined up. No position, no safety net.
As the academic job market is brutal, taking time off before securing my next position felt like career suicide.
1/10
Something that might sound crazy: when I finished my postdoc, I didn't have a job lined up. No position, no safety net.
As the academic job market is brutal, taking time off before securing my next position felt like career suicide.
1/10
Post 1:
𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐮𝐩 𝐭𝐡𝐞 𝐭𝐞𝐚𝐦 𝐢𝐬 𝐰𝐡𝐞𝐫𝐞 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐞𝐟𝐟𝐨𝐫𝐭 𝐬𝐡𝐨𝐮𝐥𝐝 𝐠𝐨.
When I posted my first position, not surprisingly, I wasn't known as a young PI. Yet I received over 250 applications for that single position.
How? 🧵
𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐮𝐩 𝐭𝐡𝐞 𝐭𝐞𝐚𝐦 𝐢𝐬 𝐰𝐡𝐞𝐫𝐞 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐞𝐟𝐟𝐨𝐫𝐭 𝐬𝐡𝐨𝐮𝐥𝐝 𝐠𝐨.
When I posted my first position, not surprisingly, I wasn't known as a young PI. Yet I received over 250 applications for that single position.
How? 🧵
June 2, 2025 at 4:25 PM
Post 1:
𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐮𝐩 𝐭𝐡𝐞 𝐭𝐞𝐚𝐦 𝐢𝐬 𝐰𝐡𝐞𝐫𝐞 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐞𝐟𝐟𝐨𝐫𝐭 𝐬𝐡𝐨𝐮𝐥𝐝 𝐠𝐨.
When I posted my first position, not surprisingly, I wasn't known as a young PI. Yet I received over 250 applications for that single position.
How? 🧵
𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐮𝐩 𝐭𝐡𝐞 𝐭𝐞𝐚𝐦 𝐢𝐬 𝐰𝐡𝐞𝐫𝐞 𝐭𝐡𝐞 𝐦𝐨𝐬𝐭 𝐞𝐟𝐟𝐨𝐫𝐭 𝐬𝐡𝐨𝐮𝐥𝐝 𝐠𝐨.
When I posted my first position, not surprisingly, I wasn't known as a young PI. Yet I received over 250 applications for that single position.
How? 🧵
Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩
7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms.
Team synergy > individual brilliance. www.nature.com/articles/s41...
7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms.
Team synergy > individual brilliance. www.nature.com/articles/s41...
April 22, 2025 at 3:58 PM
Our Nature Biotech paper hit 225K+ accesses in 3 months! 🤩
7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms.
Team synergy > individual brilliance. www.nature.com/articles/s41...
7 first authors from computer science, biology & chemistry prove that great science is teamwork. We combined AI & imaging to visualize single cells across whole organisms.
Team synergy > individual brilliance. www.nature.com/articles/s41...
We build some of the most advanced AI for biomedical research, leveraging unique data and algorithms to drive precision medicine at scale. People ask if AI will replace humans. It isn’t about idea generation—it’s about selecting and implementing the right ideas with minimal effort & maximum impact.
March 18, 2025 at 3:27 PM
We build some of the most advanced AI for biomedical research, leveraging unique data and algorithms to drive precision medicine at scale. People ask if AI will replace humans. It isn’t about idea generation—it’s about selecting and implementing the right ideas with minimal effort & maximum impact.
Germany’s Science Minister @cem_oezdemir is spot on—we must welcome top scientific talent, especially as the US’s political attitude toward scientists shifts. Many exciting AI & biotech roles opening soon at our biotech @deeppiction.bsky.social. @danyalbayaz.bsky.social www.n-tv.de/politik/Grue...
"Ziel der Trump-Regierung ist ein Regime Change - auch in Deutschland"
Die Trump-Regierung streicht Forschungsmittel, die Stimmung in den USA kippt. "Sollten die Amerikaner ihre besten Wissenschaftler verprellen, müssen wir das für uns nutzen", appelliert Cem Özdemir, Bu...
www.n-tv.de
March 1, 2025 at 6:23 AM
Germany’s Science Minister @cem_oezdemir is spot on—we must welcome top scientific talent, especially as the US’s political attitude toward scientists shifts. Many exciting AI & biotech roles opening soon at our biotech @deeppiction.bsky.social. @danyalbayaz.bsky.social www.n-tv.de/politik/Grue...
Reposted by Ali Maximilian Erturk
Want to know what we do at our startup Deep Piction? Check out our paper with Denali Therapeutics. Using our proprietary clearing & imaging technologies, we mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in whole mouse bodies and monkey brains. go.nature.com/3Xifva2
February 26, 2025 at 5:04 PM
Want to know what we do at our startup Deep Piction? Check out our paper with Denali Therapeutics. Using our proprietary clearing & imaging technologies, we mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in whole mouse bodies and monkey brains. go.nature.com/3Xifva2
Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...
February 26, 2025 at 8:33 AM
Excited to share our latest work with Denali Therapeutics as Deep Piction. Using our proprietary clearing & imaging, we’ve mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in both whole mouse bodies and monkey brains. nature.com/articles/s41...
Reposted by Ali Maximilian Erturk
Single Cell Precision Nanocarrier Identification tracks & quantifies targeted drug-delivery by nanocarriers at single-cell resolution
📹: @erturklab.bsky.social lab @www.helmholtz-munich.de
in @naturebiotech.bsky.social
➡️: bpod.org.uk/archive/2025...
📹: @erturklab.bsky.social lab @www.helmholtz-munich.de
in @naturebiotech.bsky.social
➡️: bpod.org.uk/archive/2025...
February 19, 2025 at 10:44 AM
Single Cell Precision Nanocarrier Identification tracks & quantifies targeted drug-delivery by nanocarriers at single-cell resolution
📹: @erturklab.bsky.social lab @www.helmholtz-munich.de
in @naturebiotech.bsky.social
➡️: bpod.org.uk/archive/2025...
📹: @erturklab.bsky.social lab @www.helmholtz-munich.de
in @naturebiotech.bsky.social
➡️: bpod.org.uk/archive/2025...