Markus Elsner
@markuselsner.bsky.social
Deputy Director of the Institute for Intelligent Biotechnologies at HelmholtzMunich, former editor @naturebiotech.bsky.social, all views expressed here are my own
We went to see the fantastic exhibition on Marcus Aurelius in Trier today. Really worth a visit (ends in two weeks, though)
November 8, 2025 at 10:39 PM
We went to see the fantastic exhibition on Marcus Aurelius in Trier today. Really worth a visit (ends in two weeks, though)
at least ChatGPT is honest today (not only the doi was fictitious):
June 23, 2025 at 8:57 AM
at least ChatGPT is honest today (not only the doi was fictitious):
First time outdoor office this year 😁
March 20, 2025 at 10:40 AM
First time outdoor office this year 😁
Want to know what we do at our startup Deep Piction? Check out our paper with Denali Therapeutics. Using our proprietary clearing & imaging technologies, we mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in whole mouse bodies and monkey brains. go.nature.com/3Xifva2
February 26, 2025 at 5:04 PM
Want to know what we do at our startup Deep Piction? Check out our paper with Denali Therapeutics. Using our proprietary clearing & imaging technologies, we mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in whole mouse bodies and monkey brains. go.nature.com/3Xifva2
Auch Geisenheim stemmt sich gegen Menschenfeindlichkeit
February 16, 2025 at 3:33 PM
Auch Geisenheim stemmt sich gegen Menschenfeindlichkeit
Demo gegen Rechts in Wiesbaden m
January 31, 2025 at 5:15 PM
Demo gegen Rechts in Wiesbaden m
Wir hatten ein Thema
December 31, 2024 at 2:44 PM
Wir hatten ein Thema
Found this old postcard today. Seems very appropriate for 2025
December 22, 2024 at 11:15 AM
Found this old postcard today. Seems very appropriate for 2025
Also contributing to #FluorescenceFriday
(also follow our lab account @erturklab.bsky.social for more stuff like this)
(also follow our lab account @erturklab.bsky.social for more stuff like this)
November 22, 2024 at 2:21 PM
Also contributing to #FluorescenceFriday
(also follow our lab account @erturklab.bsky.social for more stuff like this)
(also follow our lab account @erturklab.bsky.social for more stuff like this)
Frankfurt gegen Rechts!
January 20, 2024 at 4:33 PM
Frankfurt gegen Rechts!
Frankfurt gegen Rechts! Römer komplett überfüllt!
January 20, 2024 at 2:55 PM
Frankfurt gegen Rechts! Römer komplett überfüllt!
October 1, 2023 at 8:41 PM
Das finde ich ziemlich schockierend
September 25, 2023 at 3:24 PM
Das finde ich ziemlich schockierend
Most of the team and of the collaborators have not made the jump from the X site, but a big shout-out to all of them
August 11, 2023 at 7:46 AM
Most of the team and of the collaborators have not made the jump from the X site, but a big shout-out to all of them
10/n Speculation: Imagine sensors detecting brain health through your skull. Our findings offer hope for early diagnosis & easy follow-up interventions for brain diseases impacting millions globally. The skull's accessibility might even facilitate delivering treatments to the brain.
August 11, 2023 at 7:45 AM
10/n Speculation: Imagine sensors detecting brain health through your skull. Our findings offer hope for early diagnosis & easy follow-up interventions for brain diseases impacting millions globally. The skull's accessibility might even facilitate delivering treatments to the brain.
7/n Results 4) Clinical application: TSPO-positron-emission-tomography in the human skull mirrored the underlying brain inflammation in diverse diseases. In stroke patients, inflammation decreased over time, whereas for AD patients, it increased.
August 11, 2023 at 7:40 AM
7/n Results 4) Clinical application: TSPO-positron-emission-tomography in the human skull mirrored the underlying brain inflammation in diverse diseases. In stroke patients, inflammation decreased over time, whereas for AD patients, it increased.
6/n Results 3) Human imaging data: Embracing our innovative clearing technologies, we made intact human brain-meninges-skull pieces transparent. Surprisingly, we found that SMCs in humans extend beyond the dura, opening up to the sub-dural space!
August 11, 2023 at 7:38 AM
6/n Results 3) Human imaging data: Embracing our innovative clearing technologies, we made intact human brain-meninges-skull pieces transparent. Surprisingly, we found that SMCs in humans extend beyond the dura, opening up to the sub-dural space!
5/n Results 2) Human molecular data: We used proteomics and found a distinct skull proteome compared to vertebra and pelvis. Surprisingly, we identified many unique synaptic proteins in the skull! This might suggest bi-directional communication between the skull and brain.
August 11, 2023 at 7:37 AM
5/n Results 2) Human molecular data: We used proteomics and found a distinct skull proteome compared to vertebra and pelvis. Surprisingly, we identified many unique synaptic proteins in the skull! This might suggest bi-directional communication between the skull and brain.
4/n Results 1) Mouse molecular data : We used scRNAseq and proteomics and found that bone marrow cells are heterogeneous throughout the body, and the skull has a unique molecular makeup.
August 11, 2023 at 7:36 AM
4/n Results 1) Mouse molecular data : We used scRNAseq and proteomics and found that bone marrow cells are heterogeneous throughout the body, and the skull has a unique molecular makeup.
3/n Motivation: Our lab and others have recently shown that there are connections between the skull and the meningeal surface of the brain (SMCs) with immune cell trafficking. Thus, the skull might be involved in regulating neuroinflammation.
August 11, 2023 at 7:35 AM
3/n Motivation: Our lab and others have recently shown that there are connections between the skull and the meningeal surface of the brain (SMCs) with immune cell trafficking. Thus, the skull might be involved in regulating neuroinflammation.
2/n Background: Neuroinflammation, the brain's immune system reaction common in disorders like stroke and dementia, can be like a fire damaging a house. Controlling it is tough as the brain isn't easily accessible.
August 11, 2023 at 7:33 AM
2/n Background: Neuroinflammation, the brain's immune system reaction common in disorders like stroke and dementia, can be like a fire damaging a house. Controlling it is tough as the brain isn't easily accessible.
Love this!
(stole this from @GlobalEcoGuy on the other place)
(stole this from @GlobalEcoGuy on the other place)
August 4, 2023 at 1:33 PM
Love this!
(stole this from @GlobalEcoGuy on the other place)
(stole this from @GlobalEcoGuy on the other place)