Lydia Becker Institute
@lydiabeckeriii.bsky.social
Researchers from the Lydia Becker Institute of Immunology & Inflammation at The University of Manchester. Fundamental and translational immunology addressing key concepts in health & disease.
https://sites.manchester.ac.uk/lydia-becker-institute/
https://sites.manchester.ac.uk/lydia-becker-institute/
Reposted by Lydia Becker Institute
Very much looking forward to this meeting in June 2026: meetings.embo.org/event/26-pat...
Pathogen Immunity and Signalling
Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…
meetings.embo.org
January 23, 2026 at 1:42 PM
Very much looking forward to this meeting in June 2026: meetings.embo.org/event/26-pat...
Stroke patients are highly vulnerable to infection, but why?
New research shows the "fight-or-flight" response releases noradrenaline, directly impairing B cells & their ability to produce antibodies - opening new pathways to protect patients during recovery.
sites.manchester.ac.uk/lydia-becker...
New research shows the "fight-or-flight" response releases noradrenaline, directly impairing B cells & their ability to produce antibodies - opening new pathways to protect patients during recovery.
sites.manchester.ac.uk/lydia-becker...
Stroke and “fight-or-flight” response weakens the immune system
New research from The University of Manchester reveals how the "fight-or-flight" response weakens the immune system after a stroke, increasing infection risk.
sites.manchester.ac.uk
January 22, 2026 at 8:29 AM
Stroke patients are highly vulnerable to infection, but why?
New research shows the "fight-or-flight" response releases noradrenaline, directly impairing B cells & their ability to produce antibodies - opening new pathways to protect patients during recovery.
sites.manchester.ac.uk/lydia-becker...
New research shows the "fight-or-flight" response releases noradrenaline, directly impairing B cells & their ability to produce antibodies - opening new pathways to protect patients during recovery.
sites.manchester.ac.uk/lydia-becker...
Reposted by Lydia Becker Institute
❗Cross-presentation shapes neoantigen visibility and cancer immunogenicity in #NatureImmunology🤯
www.nature.com/articles/s41...
Huge congratulations @drjonlim.bsky.social 🥂
Inspired and so lucky to have you in #Manchester 🐝
Congratulations to #OliverSchulz, @reisesousalab.bsky.social , @crick.ac.uk
www.nature.com/articles/s41...
Huge congratulations @drjonlim.bsky.social 🥂
Inspired and so lucky to have you in #Manchester 🐝
Congratulations to #OliverSchulz, @reisesousalab.bsky.social , @crick.ac.uk
January 14, 2026 at 10:27 PM
❗Cross-presentation shapes neoantigen visibility and cancer immunogenicity in #NatureImmunology🤯
www.nature.com/articles/s41...
Huge congratulations @drjonlim.bsky.social 🥂
Inspired and so lucky to have you in #Manchester 🐝
Congratulations to #OliverSchulz, @reisesousalab.bsky.social , @crick.ac.uk
www.nature.com/articles/s41...
Huge congratulations @drjonlim.bsky.social 🥂
Inspired and so lucky to have you in #Manchester 🐝
Congratulations to #OliverSchulz, @reisesousalab.bsky.social , @crick.ac.uk
Tomorrow we're excited to welcome Dr Paras Anand from @imperialcollegeldn.bsky.social to discuss his latest research on how lipid metabolism acts as a critical checkpoint in inflammasome activation.
📆 Thursday 22nd Jan
🕛 12:00 PM
📍 Michael Smith Lecture Theatre
#ImmunoSky @britsocimm.bsky.social
📆 Thursday 22nd Jan
🕛 12:00 PM
📍 Michael Smith Lecture Theatre
#ImmunoSky @britsocimm.bsky.social
January 21, 2026 at 4:20 PM
Tomorrow we're excited to welcome Dr Paras Anand from @imperialcollegeldn.bsky.social to discuss his latest research on how lipid metabolism acts as a critical checkpoint in inflammasome activation.
📆 Thursday 22nd Jan
🕛 12:00 PM
📍 Michael Smith Lecture Theatre
#ImmunoSky @britsocimm.bsky.social
📆 Thursday 22nd Jan
🕛 12:00 PM
📍 Michael Smith Lecture Theatre
#ImmunoSky @britsocimm.bsky.social
Reposted by Lydia Becker Institute
Great to see two papers out that show the benefits of RSV vaccination (monoclonal treatment) to prevent severe RSV infection. A quick thread to unpick what these vaccines are as there are 2 quite different products in clinical use and it can be confusing what the terminology means. #HealthPolicy 🧵
Universal nirsevimab slashes RSV infant hospitalizations, study suggests
www.cidrap.umn.edu
January 14, 2026 at 8:20 AM
Great to see two papers out that show the benefits of RSV vaccination (monoclonal treatment) to prevent severe RSV infection. A quick thread to unpick what these vaccines are as there are 2 quite different products in clinical use and it can be confusing what the terminology means. #HealthPolicy 🧵
For our first @britsocimm.bsky.social MIG Seminar of 2026,
Dr Louisa James @louisakjames.bsky.social from @qmul.bsky.social will present:
“Tissue resident B cells and antibody production in the human airway”
🗓️ Thursday 15th Jan
🕛 12 pm
📍 Michael Smith Lecture Theatre
#ImmunoSky
Dr Louisa James @louisakjames.bsky.social from @qmul.bsky.social will present:
“Tissue resident B cells and antibody production in the human airway”
🗓️ Thursday 15th Jan
🕛 12 pm
📍 Michael Smith Lecture Theatre
#ImmunoSky
January 14, 2026 at 5:24 PM
For our first @britsocimm.bsky.social MIG Seminar of 2026,
Dr Louisa James @louisakjames.bsky.social from @qmul.bsky.social will present:
“Tissue resident B cells and antibody production in the human airway”
🗓️ Thursday 15th Jan
🕛 12 pm
📍 Michael Smith Lecture Theatre
#ImmunoSky
Dr Louisa James @louisakjames.bsky.social from @qmul.bsky.social will present:
“Tissue resident B cells and antibody production in the human airway”
🗓️ Thursday 15th Jan
🕛 12 pm
📍 Michael Smith Lecture Theatre
#ImmunoSky
Reposted by Lydia Becker Institute
Great team-work behind our paper just published on stroke-induced immune cell changes, involving groups across @edinunineuro.bsky.social
@edinuni-irr.bsky.social
@ukdri.ac.uk
@lydiabeckeriii.bsky.social.
A pandemic in midst of study not anticipated at outset!
@edinuni-irr.bsky.social
@ukdri.ac.uk
@lydiabeckeriii.bsky.social.
A pandemic in midst of study not anticipated at outset!
I’m excited to start 2026 with our new collaborative research paper examining circulating B cell populations in acute ischemic stroke patients, which is particularly exciting as we see translation of our previous data from animal models into patients. www.sciencedirect.com/science/arti...
Acute ischaemic stroke alters the composition and function of circulating B cells
Distinct B cell populations are found in circulation, including those with innate-like properties, that have varied functions in pathogen protection, …
www.sciencedirect.com
January 14, 2026 at 3:49 PM
Great team-work behind our paper just published on stroke-induced immune cell changes, involving groups across @edinunineuro.bsky.social
@edinuni-irr.bsky.social
@ukdri.ac.uk
@lydiabeckeriii.bsky.social.
A pandemic in midst of study not anticipated at outset!
@edinuni-irr.bsky.social
@ukdri.ac.uk
@lydiabeckeriii.bsky.social.
A pandemic in midst of study not anticipated at outset!
Reposted by Lydia Becker Institute
I’m excited to start 2026 with our new collaborative research paper examining circulating B cell populations in acute ischemic stroke patients, which is particularly exciting as we see translation of our previous data from animal models into patients. www.sciencedirect.com/science/arti...
Acute ischaemic stroke alters the composition and function of circulating B cells
Distinct B cell populations are found in circulation, including those with innate-like properties, that have varied functions in pathogen protection, …
www.sciencedirect.com
January 12, 2026 at 3:34 PM
I’m excited to start 2026 with our new collaborative research paper examining circulating B cell populations in acute ischemic stroke patients, which is particularly exciting as we see translation of our previous data from animal models into patients. www.sciencedirect.com/science/arti...
Reposted by Lydia Becker Institute
📢Exciting opportunity here to join the Brough lab as a PDRA for 3 years studying the NLRP3 inflammasome.
🔗 www.jobs.manchester.ac.uk/Job/JobDetai...
@lydiabeckeriii.bsky.social @dns-uom.bsky.social
🔗 www.jobs.manchester.ac.uk/Job/JobDetai...
@lydiabeckeriii.bsky.social @dns-uom.bsky.social
The University of Manchester - Job Information
Find out the specifics of this job, what it does, and whether it's a fit for you.
www.jobs.manchester.ac.uk
January 7, 2026 at 1:26 PM
📢Exciting opportunity here to join the Brough lab as a PDRA for 3 years studying the NLRP3 inflammasome.
🔗 www.jobs.manchester.ac.uk/Job/JobDetai...
@lydiabeckeriii.bsky.social @dns-uom.bsky.social
🔗 www.jobs.manchester.ac.uk/Job/JobDetai...
@lydiabeckeriii.bsky.social @dns-uom.bsky.social
Reposted by Lydia Becker Institute
Another great output from a joyful long-term collaboration between Montevideo and Manchester
onlinelibrary.wiley.com/doi/10.1111/...
Published in the excellent journal onlinelibrary.wiley.com/toc/13653024...
onlinelibrary.wiley.com/doi/10.1111/...
Published in the excellent journal onlinelibrary.wiley.com/toc/13653024...
Parasite Immunology: Vol 47, No 12
Click on the title to browse this issue
onlinelibrary.wiley.com
December 29, 2025 at 2:06 PM
Another great output from a joyful long-term collaboration between Montevideo and Manchester
onlinelibrary.wiley.com/doi/10.1111/...
Published in the excellent journal onlinelibrary.wiley.com/toc/13653024...
onlinelibrary.wiley.com/doi/10.1111/...
Published in the excellent journal onlinelibrary.wiley.com/toc/13653024...
Reposted by Lydia Becker Institute
Isn't this the coolest Christmas present (or miracle) for a #gdTcell aficionado?! Our latest preprint showing the role of BATF3 on gd T cells is ou on bioRxiv:
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
BATF3 controls the homeostatic maintenance and function of innate-like γδ T cells
γδ T cells compose an evolutionarily conserved lineage of lymphocytes, with both adaptive- and innate-like characteristics, contributing to tissue homeostasis, immune surveillance, and rapid responses...
www.biorxiv.org
December 19, 2025 at 12:07 PM
Isn't this the coolest Christmas present (or miracle) for a #gdTcell aficionado?! Our latest preprint showing the role of BATF3 on gd T cells is ou on bioRxiv:
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Lydia Becker Institute
Great Lab Christmas Lunch Festivities. I love this gang!!
December 18, 2025 at 8:16 PM
Great Lab Christmas Lunch Festivities. I love this gang!!
Reposted by Lydia Becker Institute
💭 Just imagine if Greater Manchester had the best health in the world...
'Just Imagine If', in partnership with Manchester Museum and Healthier Futures, are inviting you join a conversation on Monday 9 February to discuss how to make this a reality.
'Just Imagine If', in partnership with Manchester Museum and Healthier Futures, are inviting you join a conversation on Monday 9 February to discuss how to make this a reality.
December 18, 2025 at 12:12 PM
💭 Just imagine if Greater Manchester had the best health in the world...
'Just Imagine If', in partnership with Manchester Museum and Healthier Futures, are inviting you join a conversation on Monday 9 February to discuss how to make this a reality.
'Just Imagine If', in partnership with Manchester Museum and Healthier Futures, are inviting you join a conversation on Monday 9 February to discuss how to make this a reality.
🍃🔬 We’re proud to share that our labs at AV Hill and CTF have now both achieved Silver-level LEAF Awards
A great milestone in our ongoing commitment to sustainable research practices + big thank you to our LEAF Champions @thelabninja.bsky.social Sara Kirkham and @maanalayeghi.bsky.social #ImmunoSky
A great milestone in our ongoing commitment to sustainable research practices + big thank you to our LEAF Champions @thelabninja.bsky.social Sara Kirkham and @maanalayeghi.bsky.social #ImmunoSky
December 17, 2025 at 4:08 PM
🍃🔬 We’re proud to share that our labs at AV Hill and CTF have now both achieved Silver-level LEAF Awards
A great milestone in our ongoing commitment to sustainable research practices + big thank you to our LEAF Champions @thelabninja.bsky.social Sara Kirkham and @maanalayeghi.bsky.social #ImmunoSky
A great milestone in our ongoing commitment to sustainable research practices + big thank you to our LEAF Champions @thelabninja.bsky.social Sara Kirkham and @maanalayeghi.bsky.social #ImmunoSky
Reposted by Lydia Becker Institute
“Philanthropy is a catalyst - it pump‑primes research and unlocks breakthroughs” - Prof Stuart Allan.
Ep 7 of The Brain Fix Podcast: Philanthropy in neuroscience and UoM's #ChallengeAccepted.
🎙️Listen: the-brain-fix.transistor.fm/episodes/cha...
🎞️Watch on YouTube: youtu.be/BqICX9EgAHw?...
Ep 7 of The Brain Fix Podcast: Philanthropy in neuroscience and UoM's #ChallengeAccepted.
🎙️Listen: the-brain-fix.transistor.fm/episodes/cha...
🎞️Watch on YouTube: youtu.be/BqICX9EgAHw?...
December 17, 2025 at 1:15 PM
“Philanthropy is a catalyst - it pump‑primes research and unlocks breakthroughs” - Prof Stuart Allan.
Ep 7 of The Brain Fix Podcast: Philanthropy in neuroscience and UoM's #ChallengeAccepted.
🎙️Listen: the-brain-fix.transistor.fm/episodes/cha...
🎞️Watch on YouTube: youtu.be/BqICX9EgAHw?...
Ep 7 of The Brain Fix Podcast: Philanthropy in neuroscience and UoM's #ChallengeAccepted.
🎙️Listen: the-brain-fix.transistor.fm/episodes/cha...
🎞️Watch on YouTube: youtu.be/BqICX9EgAHw?...
Reposted by Lydia Becker Institute
Our mouse team left the Isle of May a few days ago after a very busy and successful winter season, arriving back to a festive looking Anstruther - very different to when we left mainland at the start of November. Thanks to @steelyseabirder.bsky.social and Rab and his boat crew for terrific support
December 17, 2025 at 10:53 AM
Our mouse team left the Isle of May a few days ago after a very busy and successful winter season, arriving back to a festive looking Anstruther - very different to when we left mainland at the start of November. Thanks to @steelyseabirder.bsky.social and Rab and his boat crew for terrific support
We’re now on LinkedIn! Follow the Lydia Becker Institute of Immunology & Inflammation for research highlights, people, and collaborations at the University of Manchester. #ImmunoSky #LinkedIn
www.linkedin.com/company/lydi...
www.linkedin.com/company/lydi...
Lydia Becker Institute of Immunology and Inflammation | LinkedIn
Lydia Becker Institute of Immunology and Inflammation | Uniting basic, translational and clinical research to address immunology’s complex and growing role in modern medicine. | The extensive immunolo...
www.linkedin.com
December 16, 2025 at 6:58 PM
We’re now on LinkedIn! Follow the Lydia Becker Institute of Immunology & Inflammation for research highlights, people, and collaborations at the University of Manchester. #ImmunoSky #LinkedIn
www.linkedin.com/company/lydi...
www.linkedin.com/company/lydi...
Reposted by Lydia Becker Institute
We have been out for our Christmas meal and festive darts today - and we had a lot of fun!
December 16, 2025 at 6:01 PM
We have been out for our Christmas meal and festive darts today - and we had a lot of fun!
Reposted by Lydia Becker Institute
Lovely to catch up with some of the Manchester crew this afternoon, including new addition Maya 👶, for a Christmas get together 😊🎄🎅🏻 @lydiabeckeriii.bsky.social
December 15, 2025 at 5:00 PM
Lovely to catch up with some of the Manchester crew this afternoon, including new addition Maya 👶, for a Christmas get together 😊🎄🎅🏻 @lydiabeckeriii.bsky.social
Reposted by Lydia Becker Institute
As this year draws to a close, we wanted to recap and celebrate our people, partnerships, and pioneering research at the Jeff. Stay tuned this week, as we spotlight a different theme, achievement, or story from across our research community.
www.linkedin.com/feed/update/...
www.linkedin.com/feed/update/...
As this year draws to a close, we wanted to recap and celebrate our people, partnerships, and pioneering research at the Jeff. Stay tuned this week, as we spotlight a different theme, achievement… | ...
As this year draws to a close, we wanted to recap and celebrate our people, partnerships, and pioneering research at the Jeff. Stay tuned this week, as we spotlight a different theme, achievement, or...
www.linkedin.com
December 15, 2025 at 11:25 AM
As this year draws to a close, we wanted to recap and celebrate our people, partnerships, and pioneering research at the Jeff. Stay tuned this week, as we spotlight a different theme, achievement, or story from across our research community.
www.linkedin.com/feed/update/...
www.linkedin.com/feed/update/...
The Becker is proud to be part of the RISE study to make advanced cancer treatments safer for patients 👇
Hear more about RISE + why tackling safety/toxicity in advanced therapies is centre to our programme.
We're humbled to hear from Elkie Mellor, who generously shared her lived experience. Voices like hers are a powerful reminder of why this work matters & will continue to motivate everything we do.
We're humbled to hear from Elkie Mellor, who generously shared her lived experience. Voices like hers are a powerful reminder of why this work matters & will continue to motivate everything we do.
Major study launched to make advanced cancer treatments safer for patients
A major new UK study, led by The Christie NHS Foundation Trust and The University of Manchester, has been launched to help patients with cancer better tolerate cutting-edge immunotherapy treatments li...
www.christie.nhs.uk
December 12, 2025 at 6:08 PM
The Becker is proud to be part of the RISE study to make advanced cancer treatments safer for patients 👇
Reposted by Lydia Becker Institute
🚀 Excited to share the launch of our RISE consortium.
RISE unites NHS, academic & industry partners to tackle immune-related toxicities in advanced cancer therapies, incl. CRS & neurotoxicity - centred around patient safety + quality of life.
Funded by @ukri.org MRC Prosperity Partnership Award.
RISE unites NHS, academic & industry partners to tackle immune-related toxicities in advanced cancer therapies, incl. CRS & neurotoxicity - centred around patient safety + quality of life.
Funded by @ukri.org MRC Prosperity Partnership Award.
RISE Manchester | LinkedIn
RISE Manchester | 44 followers on LinkedIn. Making advanced cancer therapies safer through science, innovation and partnership. | RISE (Reducing Immune Stress from Excess cytokine release in advanced ...
www.linkedin.com
December 12, 2025 at 5:17 PM
🚀 Excited to share the launch of our RISE consortium.
RISE unites NHS, academic & industry partners to tackle immune-related toxicities in advanced cancer therapies, incl. CRS & neurotoxicity - centred around patient safety + quality of life.
Funded by @ukri.org MRC Prosperity Partnership Award.
RISE unites NHS, academic & industry partners to tackle immune-related toxicities in advanced cancer therapies, incl. CRS & neurotoxicity - centred around patient safety + quality of life.
Funded by @ukri.org MRC Prosperity Partnership Award.
🎅 A great time had by all at the DIIIRM Christmas Party earlier this week - including a great speech from our Deputy Director and new DIIIRM Head of Division Dr John Grainger + Bingo Karaoke! 🎤
Big thank you to the amazing DIIIRM Social Committee for organising! 🎈🍾
Big thank you to the amazing DIIIRM Social Committee for organising! 🎈🍾
December 12, 2025 at 3:25 PM
🎅 A great time had by all at the DIIIRM Christmas Party earlier this week - including a great speech from our Deputy Director and new DIIIRM Head of Division Dr John Grainger + Bingo Karaoke! 🎤
Big thank you to the amazing DIIIRM Social Committee for organising! 🎈🍾
Big thank you to the amazing DIIIRM Social Committee for organising! 🎈🍾
Reposted by Lydia Becker Institute
@madhvimenon.bsky.social thank you Madhvi for organising the nomination!
December 10, 2025 at 7:53 PM
@madhvimenon.bsky.social thank you Madhvi for organising the nomination!
Earlier this week, the CIM Connect event brought together cancer, immunology and cell–matrix researchers from across Manchester to spark new ideas and collaborations
#ImmunoSky @mcrcellmatrix.bsky.social @cruk-mi.bsky.social
Find out more about the event 👇
sites.manchester.ac.uk/lydia-becker...
#ImmunoSky @mcrcellmatrix.bsky.social @cruk-mi.bsky.social
Find out more about the event 👇
sites.manchester.ac.uk/lydia-becker...
December 12, 2025 at 12:46 PM
Earlier this week, the CIM Connect event brought together cancer, immunology and cell–matrix researchers from across Manchester to spark new ideas and collaborations
#ImmunoSky @mcrcellmatrix.bsky.social @cruk-mi.bsky.social
Find out more about the event 👇
sites.manchester.ac.uk/lydia-becker...
#ImmunoSky @mcrcellmatrix.bsky.social @cruk-mi.bsky.social
Find out more about the event 👇
sites.manchester.ac.uk/lydia-becker...