Thomas Wolfers
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thomaswolfers.bsky.social
Thomas Wolfers
@thomaswolfers.bsky.social
Group Leader @ University of Tübingen
Laboratory for Mental Health Mapping
https://mhm-lab.GitHub.io

Brain/Mental Health & Machine Learning
Reposted by Thomas Wolfers
October 10, 2025 at 7:34 AM
Reposted by Thomas Wolfers
"Tao is one of the most prominent mathematicians and academics to publicly oppose the administration’s actions, calling them an “existential threat” to his field, and academic science, more broadly. He said public advocacy is a priority over his research, for now."

www.nbcnews.com/science/scie...
The 'Mozart of Math' rarely speaks about politics. The wide-ranging cuts to science funding made him change that.
UCLA's Terence Tao called the Trump administration's actions an "existential threat" to academic research in the U.S.
www.nbcnews.com
August 28, 2025 at 2:38 AM
Reposted by Thomas Wolfers
Promise tariffs ⟶ faff around ⟶ announce tariffs ⟶ pause tariffs ⟶ promise deals ⟶ court rules tariffs illegal ⟶ appeal ⟶ court order stayed ⟶ make no deals ⟶ 90 days expires ⟶ delay tariffs again ⟶ announce tariffs again ⟶ appeals court rules tariffs illegal again ⟶ you are here
August 30, 2025 at 4:28 PM
Reposted by Thomas Wolfers
🧠 Education boosts memory levels but not brain aging resistance

A new study across 33 countries found more education links to better memory and larger brain volume, but not slower cognitive or brain decline.

🔗 www.nature.com/articles/s41...

#SciComm 🧪
Reevaluating the role of education on cognitive decline and brain aging in longitudinal cohorts across 33 Western countries - Nature Medicine
In a large cross-national study, education was linked to better memory and larger brain volumes but not to slower cognitive or brain decline with age, suggesting that the association reflects early-li...
www.nature.com
August 12, 2025 at 7:04 AM
Reposted by Thomas Wolfers
I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
Reposted by Thomas Wolfers
He just announced the 90 day pause.
Start a trade war with China. Escalate when they retaliate. Repeat until a near-embargo. Meet to agree on a 90 day pause. Get nervous about that agreement, so re-meet to re-agree to that 90 day pause. As the 90 day pause draws to a close, meet to agree to a 90 day pause.
August 11, 2025 at 6:31 PM
Reposted by Thomas Wolfers
💥🧠🧬Finally out!! Our new paper on the overlapping genetic basis of brain structures and psychiatric disorders has been published in Nature Mental Health. The full list of shared genetic loci is also available online. Thank you so much, Aaron and all co-authors.
www.nature.com/articles/s44...
The overlapping genetic architecture of psychiatric disorders and cortical brain structure - Nature Mental Health
This study highlights sex differences in major depressive disorder using resting-state functional magnetic resonance imaging. Findings suggest hormonal fluctuations influence onset, emphasizing the ne...
www.nature.com
August 11, 2025 at 6:54 PM
Reposted by Thomas Wolfers
Big data won't solve anything if it's crappy data. 😒

We need to 1) train people to inspect datasets before using them and 2) ensure that openly shared data is good data.

www.thetransmitter.org/spectrum/poo...
Poor image quality introduces systematic bias into MRI data
Analyses that include low-quality MRI data underestimate cortical thickness and overestimate surface area, according to new work from the ABCD Study.
www.thetransmitter.org
August 1, 2025 at 11:36 PM
Reposted by Thomas Wolfers
A cross-species study captured an emotional brain state characterized by lingering brain activity in higher-order areas. “It’s one of those moments where you’re getting a first glimpse at a vast and complex landscape,” says @deisseroth.bsky.social.

By @callimcflurry.bsky.social

bit.ly/3U33raF
Eye puffs prompt separable sensory, affective brain responses in mice, people
Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.
bit.ly
July 29, 2025 at 2:13 PM
Reposted by Thomas Wolfers
Work by Tara Arbab, Ingo Willuhn et al. on neural biomarkers in OCD was published in Nature Mental Health.🗨️Arbab about the study: "It's unique that we were able to measure deep brain activity with very high spatial and temporal precision.” @willuhnlab.bsky.social www.amsterdamumc.org/en/research/...
www.amsterdamumc.org
July 28, 2025 at 2:14 PM
Reposted by Thomas Wolfers
trickle down economics
trickle down economic
trickle down economi
trickle down econom
trickle down econo
trickle down econ
trickle down eco
trickle down ec
trickle down e
trickle down
trickle dow
trickle do
trickle d
trickle
trickl
trick
June 30, 2025 at 10:15 PM
Reposted by Thomas Wolfers
ICYMI: New online! Brain–computer interface restores naturalistic speech to a man with ALS
Brain–computer interface restores naturalistic speech to a man with ALS
Nature Reviews Neurology, Published online: 08 July 2025; doi:10.1038/s41582-025-01122-6A voice-synthesis neuroprosthesis based on a brain–computer interface has restored instantaneous, natural-sounding speech to a man with amyotrophic lateral sclerosis.
bit.ly
July 10, 2025 at 2:01 AM
Reposted by Thomas Wolfers
Pleased to say that our story of how a theory of self-supervised learning in cortical layers accounts for several experimental observations is now out 🎉
www.nature.com/articles/s41...
Self-supervised predictive learning accounts for cortical layer-specificity - Nature Communications
How the cortex learns an internal representation of the world and why the cortex relies on a layered structure remain poorly understood. Here, the authors propose a computational theory in which the n...
www.nature.com
July 4, 2025 at 5:17 PM
Reposted by Thomas Wolfers
Reposted by Thomas Wolfers
I defended my PhD! You can watch it on YouTube here: youtu.be/OCfqTtPy1KM?...
June 23, 2025 at 8:47 AM
Reposted by Thomas Wolfers
David Leeftink's first PhD thesis work is now available on arXiv! Probabilistic Pontryagin's Maximum Principle for Continuous-Time Model-Based Reinforcement Learning, check it out!
April 5, 2025 at 5:21 PM
Reposted by Thomas Wolfers
Cerebellar circuit computations for predictive motor control — a Review by Katrina P. Nguyen & Abigail L. Person

www.nature.com/articles/s41...

#neuroscience #neuroskyence
Cerebellar circuit computations for predictive motor control - Nature Reviews Neuroscience
The cerebellum helps ensure the speed and accuracy of movements, but its precise contributions to movement control are unclear. Nguyen and Person here evaluate evidence for and against feedforward mot...
www.nature.com
June 18, 2025 at 1:36 PM
Congratulations @Saige to a wonderful PhD Defense!
June 19, 2025 at 6:18 AM
Reposted by Thomas Wolfers
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidity and relieves various autistic traits.

@takamitsuw.bsky.social

www.nature.com/articles/s41...
Noninvasive reduction of neural rigidity alters autistic behaviors in humans - Nature Neuroscience
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidit...
www.nature.com
June 13, 2025 at 6:48 PM
Reposted by Thomas Wolfers
🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis.

Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3

www.medrxiv.org/content/10.1...
May 12, 2025 at 1:09 AM
Reposted by Thomas Wolfers
Check out our latest open data release. n=240, most with a dsm-5 dx with extensive phenotying (~100 scales/subscale), rest and task functional imaging. See @carrisacocuzza.bsky.social's thread below for deets and links 👇🏾👇🏾👇🏾
June 4, 2025 at 11:45 PM