Sidhant Chopra
@sidchop.bsky.social
Neuroscientist and psychologist interested in better treatments, brains & psychosis. Research Fellow @UniMelb @orygen_aus
Pinned
Sidhant Chopra
@sidchop.bsky.social
· Mar 24
🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia"
medrxiv.org/content/10.1...
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
medrxiv.org/content/10.1...
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
Reposted by Sidhant Chopra
Just published! 🎉 My new blog post tackles the mighty `apply()` function in R. Demystify `MARGIN` and master operations from matrices to 5D neuroimaging data. Say goodbye to loops! 🧠📊
drmo.site/k40xD5
#RStats #DataScience #Neuroimaging
drmo.site/k40xD5
#RStats #DataScience #Neuroimaging
Mastering Apply: From Matrices to Multidimensional Neuroimaging Data - Dr. Mowinckel’s
Master apply() in R for multidimensional data analysis.
drmo.site
November 1, 2025 at 6:53 PM
Just published! 🎉 My new blog post tackles the mighty `apply()` function in R. Demystify `MARGIN` and master operations from matrices to 5D neuroimaging data. Say goodbye to loops! 🧠📊
drmo.site/k40xD5
#RStats #DataScience #Neuroimaging
drmo.site/k40xD5
#RStats #DataScience #Neuroimaging
Reposted by Sidhant Chopra
Thrilled to share a new paper in @jamapsychiatry.com on path asymmetry in complex dynamic systems of psychopathology! jamanetwork.com/journals/jam...
With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳
With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳
Path Asymmetry in Complex Dynamic Systems of Psychopathology
This article illustrates the assumption of path symmetry in current theories of psychopathology and calls for the development of dynamical systems of mental illness that incorporate asymmetry.
jamanetwork.com
October 29, 2025 at 8:42 PM
Thrilled to share a new paper in @jamapsychiatry.com on path asymmetry in complex dynamic systems of psychopathology! jamanetwork.com/journals/jam...
With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳
With amazing collaborators @tfblanken.bsky.social, Han van der Maas, & Denny Borsboom 🥳
Reposted by Sidhant Chopra
Unattended working memory items are coded by persistent activity in human medial temporal lobe neurons | Nature Human Behaviour www.nature.com/articles/s41...
Unattended working memory items are coded by persistent activity in human medial temporal lobe neurons - Nature Human Behaviour
Paluch et al. show that unattended working memory items, as well as attended ones, are encoded in persistent activity in the medial temporal lobe.
www.nature.com
October 23, 2025 at 9:47 AM
Unattended working memory items are coded by persistent activity in human medial temporal lobe neurons | Nature Human Behaviour www.nature.com/articles/s41...
Reposted by Sidhant Chopra
Michael X Cohen on why he left academia/neuroscience.
mikexcohen.substack.com/p/why-i-left...
mikexcohen.substack.com/p/why-i-left...
Why I left academia and neuroscience
Don't worry, this isn't yet another story of rage-quitting.
mikexcohen.substack.com
October 6, 2025 at 5:05 PM
Michael X Cohen on why he left academia/neuroscience.
mikexcohen.substack.com/p/why-i-left...
mikexcohen.substack.com/p/why-i-left...
Reposted by Sidhant Chopra
When @laurapritschet.bsky.social & Pavel Shapturenka set out to build the 28&Me + 28&He datasets, I don't think any of us could've predicted the spectacularly creative ways the datasets would be used years later. That's the power of open science. 👇🏼
October 3, 2025 at 8:00 PM
When @laurapritschet.bsky.social & Pavel Shapturenka set out to build the 28&Me + 28&He datasets, I don't think any of us could've predicted the spectacularly creative ways the datasets would be used years later. That's the power of open science. 👇🏼
Reposted by Sidhant Chopra
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health
Major mental disorders are increasingly understood as disorders of brain development. Large and heterogeneous samples are required to define generalizable links between brain development and psychopat...
doi.org
February 27, 2025 at 8:57 PM
(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025...
Funded by National Institute of Mental Health (NIMH)
Funded by National Institute of Mental Health (NIMH)
Reposted by Sidhant Chopra
Congratulations to these Orygen early career researchers, whose innovative work has been recognised with new grants 👏
More details: bit.ly/46BpOdj
@sidchop.bsky.social @stephmiles.bsky.social
More details: bit.ly/46BpOdj
@sidchop.bsky.social @stephmiles.bsky.social
September 22, 2025 at 6:45 AM
Congratulations to these Orygen early career researchers, whose innovative work has been recognised with new grants 👏
More details: bit.ly/46BpOdj
@sidchop.bsky.social @stephmiles.bsky.social
More details: bit.ly/46BpOdj
@sidchop.bsky.social @stephmiles.bsky.social
Reposted by Sidhant Chopra
Hej, Melbourne #rstats folks! Please join me for my in-person workshop on C++ Programming for Faster Statistical Modelling in R on Monday, Sep 29!
Lot's of goodies for econometricians and statisticians here!
Register at: wombat2025.numbat.space
#rstats #rcpp
Lot's of goodies for econometricians and statisticians here!
Register at: wombat2025.numbat.space
#rstats #rcpp
September 22, 2025 at 12:07 AM
Hej, Melbourne #rstats folks! Please join me for my in-person workshop on C++ Programming for Faster Statistical Modelling in R on Monday, Sep 29!
Lot's of goodies for econometricians and statisticians here!
Register at: wombat2025.numbat.space
#rstats #rcpp
Lot's of goodies for econometricians and statisticians here!
Register at: wombat2025.numbat.space
#rstats #rcpp
Reposted by Sidhant Chopra
Neuromorphic hierarchical modular reservoirs | doi.org/10.1101/2025...
How does hierarchical modularity shape computational function? ⤵️
How does hierarchical modularity shape computational function? ⤵️
September 17, 2025 at 5:23 PM
Neuromorphic hierarchical modular reservoirs | doi.org/10.1101/2025...
How does hierarchical modularity shape computational function? ⤵️
How does hierarchical modularity shape computational function? ⤵️
Reposted by Sidhant Chopra
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
September 16, 2025 at 4:17 PM
Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
doi.org/10.1038/s420...
How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️
Reposted by Sidhant Chopra
in preparation for next week's NACS speaker, today's target article
September 12, 2025 at 2:06 PM
in preparation for next week's NACS speaker, today's target article
Reposted by Sidhant Chopra
The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
September 10, 2025 at 1:07 PM
The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
Reposted by Sidhant Chopra
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f
Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience
➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?
Check out what we found!
🧵1/n
Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience
➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism?
Check out what we found!
🧵1/n
September 10, 2025 at 3:08 PM
Reposted by Sidhant Chopra
The BRIDGE Lab has officially been launched! 🔗 bridgelab.ucsd.edu 👉 we Bridge Research in Imaging, Development, Genetics and Emerging mental health 🧠 🧬 🚸 🌉 please don't be shy to reach out if you are interested in learning more about our lab's research!
BRIDGE Lab
Welcome to the BRIDGE Lab (Bridging Research across Imaging, Development, Genetics, and Emerging Mental Health) within the Department of Psychiatry at the University of California San Diego! Our resea...
bridgelab.ucsd.edu
September 10, 2025 at 4:09 PM
The BRIDGE Lab has officially been launched! 🔗 bridgelab.ucsd.edu 👉 we Bridge Research in Imaging, Development, Genetics and Emerging mental health 🧠 🧬 🚸 🌉 please don't be shy to reach out if you are interested in learning more about our lab's research!
Reposted by Sidhant Chopra
Our latest work is now out in @natmentalhealth.nature.com! We examined the role of the basal forebrain and its influence on intrinsic brain networks in depressive and anxiety disorders.
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
Altered basal forebrain regulation of intrinsic brain networks in depressive and anxiety disorders - Nature Mental Health
Using 7T resting-state functional MRI data, the authors investigate the effective connectivity of basal forebrain areas in a transdiagnostic sample of patients with anxiety and depression and healthy ...
www.nature.com
September 9, 2025 at 12:03 AM
Our latest work is now out in @natmentalhealth.nature.com! We examined the role of the basal forebrain and its influence on intrinsic brain networks in depressive and anxiety disorders.
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
🔗 www.nature.com/articles/s44...
@psychunimelb.bsky.social, @mbciu.bsky.social, #UnimelbMDHS
Reposted by Sidhant Chopra
🔍 OHBM's SIGs and Committees spotlight research reflecting the topics and challenges that matter to their communities.
Explore their selections here: apertureneuro.org/pages/906-fe...
@ohbmenvironment.bsky.social @ohbm-com.com @ohbmossig.bsky.social @ohbmofficial.bsky.social
Explore their selections here: apertureneuro.org/pages/906-fe...
@ohbmenvironment.bsky.social @ohbm-com.com @ohbmossig.bsky.social @ohbmofficial.bsky.social
September 8, 2025 at 8:29 PM
🔍 OHBM's SIGs and Committees spotlight research reflecting the topics and challenges that matter to their communities.
Explore their selections here: apertureneuro.org/pages/906-fe...
@ohbmenvironment.bsky.social @ohbm-com.com @ohbmossig.bsky.social @ohbmofficial.bsky.social
Explore their selections here: apertureneuro.org/pages/906-fe...
@ohbmenvironment.bsky.social @ohbm-com.com @ohbmossig.bsky.social @ohbmofficial.bsky.social
Reposted by Sidhant Chopra
🔥ATTENTION!🔥
Registration for the 2026 Noosa Brain Workshop is now open!
Join us for some amazing science, sun, and surf in one of Australia's most beautiful beach towns.
Details:
tinyurl.com/arbc5pp6
Check out or incredible list of confirmed speakers. More to come...
Registration for the 2026 Noosa Brain Workshop is now open!
Join us for some amazing science, sun, and surf in one of Australia's most beautiful beach towns.
Details:
tinyurl.com/arbc5pp6
Check out or incredible list of confirmed speakers. More to come...
September 5, 2025 at 1:29 AM
🔥ATTENTION!🔥
Registration for the 2026 Noosa Brain Workshop is now open!
Join us for some amazing science, sun, and surf in one of Australia's most beautiful beach towns.
Details:
tinyurl.com/arbc5pp6
Check out or incredible list of confirmed speakers. More to come...
Registration for the 2026 Noosa Brain Workshop is now open!
Join us for some amazing science, sun, and surf in one of Australia's most beautiful beach towns.
Details:
tinyurl.com/arbc5pp6
Check out or incredible list of confirmed speakers. More to come...
Reposted by Sidhant Chopra
The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.
jobs.rutgers.edu/postings/209...
jobs.rutgers.edu/postings/209...
Human Neuroimaging Faculty Positions in Rutgers Brain Health Institute
The Center for Advanced Human Brain Imaging Research (CAHBIR), a component of the Rutgers Brain Health Institute (BHI) on the Busch campus in Piscataway, NJ, is recruiting for two open rank (Assistant...
jobs.rutgers.edu
September 5, 2025 at 7:58 PM
The @cahbir.bsky.social and @rutgersbhi.bsky.social are hiring! Multiple open area and open rank faculty jobs, wonderful colleagues, amazing resources, and one of the largest communities of brain science research groups on the planet. Please apply and share widely.
jobs.rutgers.edu/postings/209...
jobs.rutgers.edu/postings/209...
Reposted by Sidhant Chopra
🧠 We're hiring a computational postdoc!
3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN.
Lead & develop computational work, collaborate with experimentalists on psychosis/THC data.
DM for details! lnkd.in/eCMy9Jf5
3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN.
Lead & develop computational work, collaborate with experimentalists on psychosis/THC data.
DM for details! lnkd.in/eCMy9Jf5
September 3, 2025 at 7:13 AM
🧠 We're hiring a computational postdoc!
3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN.
Lead & develop computational work, collaborate with experimentalists on psychosis/THC data.
DM for details! lnkd.in/eCMy9Jf5
3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN.
Lead & develop computational work, collaborate with experimentalists on psychosis/THC data.
DM for details! lnkd.in/eCMy9Jf5
Reposted by Sidhant Chopra
Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).
If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
August 29, 2025 at 1:35 AM
Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level).
If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
Reposted by Sidhant Chopra
NIMH Data Archive is now also imposing NIST/ISO requirements (like NBDC). Not sure how many labs actually have the resources to meet these requirements. Is the golden era of open brain imaging data basically over?
August 28, 2025 at 1:01 AM
NIMH Data Archive is now also imposing NIST/ISO requirements (like NBDC). Not sure how many labs actually have the resources to meet these requirements. Is the golden era of open brain imaging data basically over?
Reposted by Sidhant Chopra
Early bird registration for #WOMBAT2025 ends this week! WOMBAT is a data analytics workshop in Melbourne featuring the latest open source software.
📅 29-30 September (day 1 is tutorials, day 2 is the main event)
📍 In-person | Melbourne CBD, Australia
wombat2025.numbat.space
📅 29-30 September (day 1 is tutorials, day 2 is the main event)
📍 In-person | Melbourne CBD, Australia
wombat2025.numbat.space
WOMBAT 2025
The Annual Workshop Organised by the Monash Business Analytics Team will be held on the 29th and 30th September 2025 at Monash University (downtown), Melbourne, Australia.
wombat2025.numbat.space
August 27, 2025 at 5:12 AM
Early bird registration for #WOMBAT2025 ends this week! WOMBAT is a data analytics workshop in Melbourne featuring the latest open source software.
📅 29-30 September (day 1 is tutorials, day 2 is the main event)
📍 In-person | Melbourne CBD, Australia
wombat2025.numbat.space
📅 29-30 September (day 1 is tutorials, day 2 is the main event)
📍 In-person | Melbourne CBD, Australia
wombat2025.numbat.space
Reposted by Sidhant Chopra
Great write up of the @nature.com study on MRI economics by @bttyeo.bsky.social's research group!
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
When powering fMRI studies, sample size is king, but scan duration can also be a powerful tool, improving phenotypic prediction and cost-efficiency, a new analysis shows
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/fmri/longer-...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/fmri/longer-...
Longer fMRI brain scans boost reliability—but only to a point
Around 30 minutes of imaging per person seems to be the “sweet spot” for linking functional connectivity differences to traits in an accurate and cost-effective way.
www.thetransmitter.org
August 21, 2025 at 3:07 PM
Great write up of the @nature.com study on MRI economics by @bttyeo.bsky.social's research group!
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
With @avramholmes.bsky.social @sidchop.bsky.social @carrisacocuzza.bsky.social
Reposted by Sidhant Chopra
Resting-state fMRI data predicts what people are thinking and how they're thinking it ⬇️
New preprint! 🧠
Our mind wanders at rest. By periodically probing ongoing thoughts during resting-state fMRI, we show these thoughts are reflected in brain network dynamics and contribute to pervasive links between functional brain architecture and everyday behavior (1/10).
doi.org/10.1101/2025...
Our mind wanders at rest. By periodically probing ongoing thoughts during resting-state fMRI, we show these thoughts are reflected in brain network dynamics and contribute to pervasive links between functional brain architecture and everyday behavior (1/10).
doi.org/10.1101/2025...
Ongoing thoughts at rest reflect functional brain organization and behavior
Resting-state functional connectivity (rsFC)-brain connectivity observed when people rest with no external tasks-predicts individual differences in behavior. Yet, rest is not idle; it involves streams...
www.biorxiv.org
August 20, 2025 at 7:58 PM
Resting-state fMRI data predicts what people are thinking and how they're thinking it ⬇️
Reposted by Sidhant Chopra
As federal support vanishes for research addressing the root causes of health disparities in the United States, we are left with a dangerous void and an urgent need to rethink science funding, says Vani Pariyadath
go.nature.com/4mlvEGo
go.nature.com/4mlvEGo
‘A whole body of health-equity research is being disappeared’ — why I resigned from the NIH
As federal support vanishes for research addressing the root causes of health disparities in the United States, we are left with a dangerous void and an urgent need to rethink science funding.
go.nature.com
August 12, 2025 at 2:53 PM
As federal support vanishes for research addressing the root causes of health disparities in the United States, we are left with a dangerous void and an urgent need to rethink science funding, says Vani Pariyadath
go.nature.com/4mlvEGo
go.nature.com/4mlvEGo