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Alessandro Gozzi

Alessandro Gozzi

@gozziale.bsky.social

1.1K followers 710 following 120 posts

Senior scientist at Istituto Italiano di Tecnologia (Rovereto, Italy)
🧠 🐁 Functional Neuroimaging, Brain (dys)connectivity and Autism
ERC Grantee
www.gozzilab.it

Neuroscience 77%

Biology 18%

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Alessandro Gozzi @gozziale.bsky.social · Mar 6

Can we use brain scans to identify biologically distinct "autisms"? And If so, how?

In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!

Find out more here 👇👇
www.biorxiv.org/content/10.1...

Thread below 🧵 1/n

Reposted by Alessandro Gozzi

Rick Betzel @richardfbetzel.bsky.social · 1d

Excited to share a new preprint, led by the inimitable @colleenhughes.bsky.social!

Individualized Mapping of Functional Brain Networks in Older Adulthood

www.biorxiv.org/content/10.6...

A short 🧵 1/

www.biorxiv.org

Reposted by Alessandro Gozzi

Jorge Mejias @jorgefmejias.bsky.social · 2d

For Spanish researchers interested in postdoc positions: my lab at Amsterdam is looking for candidates to apply for a Ramon Areces postdoctoral fellowship, to work for 2 years on compneuro and digital brains. Deadline Feb 23. Please spread the word! More info: www.fundacionareces.es/fundacionare...

Convocatorias - Fundación Ramón Areces

www.fundacionareces.es

Reposted by Alessandro Gozzi

PLOS Biology @plosbiology.org · 3d

How does superficial white matter contribute to large-scale #brain function? @borismontreal.bsky.social &co use an approach based on 3D histology & 7-Tesla MRI to reveal associations between superficial #WhiteMatter microstructure & diverse cortical properties @plosbiology.org 🧪 plos.io/460WNIz

Reposted by Alessandro Gozzi

Adeel Razi @adeelrazi.bsky.social · 3d

📢Maths in the Brain Workshop 2026 in Melbourne.

We will bring together researchers across Australia with a shared interest in understanding the brain from a quantitative perspective.

This year's keynote is delivered by Professor James Cole, University College London.

1/4🧵

Reposted by Alessandro Gozzi

Giulia Baracchini @giuliaabaracc.bsky.social · 5d

Now in press one of my last PhD projects! We traced the neurobiological profile of fMRI BOLD signal variability, a measure that has been related to age, behaviour, disease status, but had not yet been fully contextualised within the brain's multiscale architecture. www.nature.com/articles/s41...

The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization - Nature Communications

Baracchini et al. reveal that temporal variability in fMRI brain signals encodes biologically meaningful information across spatial and temporal scales, highlighting its role in healthy brain function...

Reposted by Alessandro Gozzi

Lucina Uddin @lucinauddin.bsky.social · 5d

New tour de force from @giuliaabaracc.bsky.social. Everything you ever wanted to know about brain signal variability! 🧠 www.nature.com/articles/s41...

The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization - Nature Communications

Baracchini et al. reveal that temporal variability in fMRI brain signals encodes biologically meaningful information across spatial and temporal scales, highlighting its role in healthy brain function...

Reposted by Alessandro Gozzi

Nature Human Behaviour @nathumbehav.nature.com · 7d

Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia across species

Convergent transcriptomic and connectomic controllers of information integration and its anaesthetic breakdown across mammalian brains - Nature Human Behaviour

Luppi et al. identify transcriptomic and connectomic controllers of information integration and its breakdown induced by anaesthesia in humans, macaques, marmosets and mice.

Reposted by Alessandro Gozzi

Annie G. Bryant @anniegbryant.bsky.social · 9d

The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)!

Preprint: www.biorxiv.org/content/10.6...
Website: anniegbryant.github.io/subcortex_vi...

Nine subcortical/cerebellar atlases included in the subcortex_visualization Python package (and subcortexVisualizationR package in R). The atlases are depicted in two-dimensional vector graphic format.

Reposted by Alessandro Gozzi

Alex Fornito @alexfornito.bsky.social · 10d

Our latest preprint on how regional cellular, molecular, and other forms of heterogeneity shape macroscopic wave dynamics is now out:
www.biorxiv.org/content/10.6...

For a full thread, see:
x.com/_victorbarne...

Reposted by Alessandro Gozzi

DrBreaky @drbreaky.bsky.social · 11d

People have been looking at "AI & brains" through the lens of LLMs/transformers. But what latent diffusion? (think text-to-image/video platforms such as Midjourney).

**Class conditioned latent diffusion and semantically cued hippocampus share a remarkably similar computational architecture...**

Reposted by Alessandro Gozzi

Caterina Gratton @caterinagratton.bsky.social · 14d

🚨 I'm searching for a full-time research coordinator to join my group & work on precision brain 🧠 network and cognitive control projects at both 3T and 7T. Please rt 🙌

Applications due: Feb. 26
Start date: flexible, as early as June
More 👇
#neuroskyence #PsychSciSky

Reposted by Alessandro Gozzi

David Jones @davidjonesbrain.bsky.social · 17d

🧵1/12 What if the DMN, limbic system, hippocampus, neural oscillations, gradients, dementia syndromes, mixed pathology, and aphantasia all fall out of the same generative brain computation? 🤯#endalz

Introducing #SLOD (preprint): a new #NeuroAI framework w/ @drbreaky.bsky.social

a man in a suit is making a funny face and says `` mind blown '' while standing in a bar .

ALT: a man in a suit is making a funny face and says `` mind blown '' while standing in a bar .

media.tenor.com

Reposted by Alessandro Gozzi

Richard Sever @richardsever.bsky.social · 21d

One of my concerns with AI-assisted research in biology is that we're already looking only in the lamplight and AI incentivizes us to narrow the beam. Seems like it's happening...
www.nature.com/articles/s41...

Artificial intelligence tools expand scientists’ impact but contract science’s focus - Nature

Artificial intelligence boosts individual scientists’ output, citations and career progression, but collectively narrows research diversity and reduces collaboration, concentrating work in data-rich a...

Reposted by Alessandro Gozzi

Jakub Szymanik @szymanikjakub.bsky.social · 22d

🚀 Hiring: Tenure Track Researcher at CiMeC,
UniTrento! 🧠💻

Field: #CompLing, #AI & Cognitive Modeling. Join an interdisciplinary hub (AI + Neuroscience + Psych) in beautiful Trentino! 🏔️✨

📅 Deadline: Feb 12, 12:00 CET
🔗 lavoraconnoi.unitn.it/bando-dr-val...

#AcademicJobs #NLP

Reposted by Alessandro Gozzi

Armin Raznahan @bogglerapture.bsky.social · 25d

How do gonads and sex chromosomes contribute to regional sex differences in the brain? 🤔

Our new preprint summarizes >5 years of work on this question, combining structural neuroimaging and snRNAseq within a sample of >850 mice.

www.biorxiv.org/content/10.6...

Thread below …

Gonadal and sex chromosomal contributions to sex differences in mammalian brain organization

Sex differences in brain development may contribute to well-known sex differences in behavior and neuropsychiatric risk - making it important to comprehensively map and mechanistically annotate normat...

www.biorxiv.org

Alessandro Gozzi @gozziale.bsky.social · 25d

Very cool study! Congrats 👏🏼👏🏼

Reposted by Alessandro Gozzi

Angelo Forli @aforli89.bsky.social · 26d

For decades, imaging has forced the same trade-off:
Set a frame rate → sacrifice resolution or field of view to go fast.

We break that rule

Using an EVENT-BASED CAMERA, we record neural activity without frames. Signals are captured only where and when they occur:

www.biorxiv.org/content/10.6...

Ultrafast Frame-Free Imaging of Neural Activity with Event Cameras

Frame-based fluorescence imaging has long defined how neural activity is optically measured. This approach requires acquiring all pixels within an image, regardless of whether they carry meaningful ne...

www.biorxiv.org

Reposted by Alessandro Gozzi, Yi Zhou

Sergi Roig Puiggros @sroig.bsky.social · 29d

I'm very excited to finally see this one out in @natneuro.nature.com ! It has been an incredible journey alongside extremely talented people! Thanks to everyone involved and enjoy the reading! 1/n
www.nature.com/articles/s41...

Position-independent emergence of neocortical neuron molecular identity, connectivity and function - Nature Neuroscience

Even when neocortical neurons form in abnormal locations, they retain their identity and function, revealing that brain circuit formation can be guided by intrinsic developmental programs rather than ...

Reposted by Dorothy Bishop, Alessandro Gozzi

Steve Smith @fmrib-steve.bsky.social · 29d

Preprint on PANDORA by Aslan Abivardi:

A massive archive of UK Biobank brain imaging from 82K subjects. For each of 98 sub-modalities (e.g., FA from dMRI), the images are collated into a convenient subjectsXvoxels HDF5 file.

pages.fmrib.ox.ac.uk/pandora/web/

www.medrxiv.org/content/10.6...

Reposted by Markus Appel, Alessandro Gozzi

Eiko Fried @eikofried.bsky.social · Jan 5

Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity.

www.nature.com/articles/s41...

BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience

Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...

Reposted by Márk E. Hauber, Alessandro Gozzi

Cheng Huang @huangchengwashu.bsky.social · Jan 2

Recent review about long-range axons rdcu.be/eXeDG

Long-range axon branching: contributions to brain network plasticity and repair

Nature Reviews Neuroscience - Connectome reconstructions across multiple species reveal that the morphology of axonal projections is highly variable, even between neurons of the same location or...

Reposted by Alessandro Gozzi

Cedric Boeckx @cedricboeckx.bsky.social · Dec 30

Very happy to see this great study by @skrohn.bsky.social @carstenfinke.bsky.social @engra.me @sofievalk.bsky.social on brain shape & human brain development, out in @natneuro.nature.com
🧪🧠
www.nature.com/articles/s41...

Fractal analysis of brain shape formation predicts age and genetic similarity in human newborns - Nature Neuroscience

Fractal analysis of structural MRI captures the formation of brain shape in human newborns and outperforms other morphological measures in predicting infant age and genetic similarity, including the i...

Reposted by Alessandro Gozzi

PessoaBrain @pessoabrain.bsky.social · Dec 28

𝗧𝗵𝗲 𝗘𝗻𝘁𝗮𝗻𝗴𝗹𝗲𝗱 𝗕𝗿𝗮𝗶𝗻
Annual reminder that the book is open access.
How do we think of the brain as a deeply interconnected system with highly distributed, non hierarchical processing.
Want to learn about the brain from a fresh perspective?
#neuroskyence
mitpress.mit.edu/978026254460...

The Entangled Brain

Popular neuroscience accounts often focus on specific mind-brain aspects like addiction, cognition, or memory, but The Entangled Brain tackles a much bigger ...

mitpress.mit.edu

Reposted by Alessandro Gozzi

Bryan Roth @zenbrainest.bsky.social · Dec 27

Postdoctoral fellowship available in structure guided drug discovery in @RothLabUNC
Please RT

Reposted by Jennifer Bussell, Alessandro Gozzi

Ben Hayden @benhayden.bsky.social · Dec 23

New Perspective from myself, Sarah Heilbronner and @myoo.bsky.social . “Rethinking the centrality of brain areas in understanding functional organization” in Nature Neuroscience. 🧵

rdcu.be/eVZ1A

Rethinking the centrality of brain areas in understanding functional organization

Nature Neuroscience - Parcellation of the cortex into functionally modular brain areas is foundational to neuroscience. Here, Hayden, Heilbronner and Yoo question the central status of brain areas...

Alessandro Gozzi @gozziale.bsky.social · Dec 19

Wrapping up 2025 with the lab.

Proud moments (including some I once thought impossible) and so many failures, living side by side, as science does. We stuck with it together. Grateful for the shared effort, trust, and fun that shaped this year.

Wishing everyone a peaceful holiday break!

Reposted by Alessandro Gozzi

Rick Betzel @richardfbetzel.bsky.social · Dec 12

Just provisionally accepted -- preprint updated | The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction | www.biorxiv.org/content/10.1...

The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction

Functional connectivity (FC) is frequently operationalized as a correlation. Many studies have examined changes in correlation networks across time, claiming to link time-varying fluctuations to ongoi...

www.biorxiv.org

Reposted by Alessandro Gozzi

Alex Fornito @alexfornito.bsky.social · Dec 11

Come and join our team! We are looking for a Research Officer to help with recruitment and assessment on a large-scale human brain imaging study:

careers.pageuppeople.com/513/cw/en/jo...

careers.pageuppeople.com

Reposted by Alessandro Gozzi

PessoaBrain @pessoabrain.bsky.social · Dec 10

𝗕𝗿𝗮𝗶𝗻 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀, 𝘄𝗵𝗮𝘁 𝗮𝗿𝗲 𝘁𝗵𝗲𝘆?
@lucinauddin.bsky.social explains many of the challenges and controversies! Great discussion too.
Check out the latest Neuroscience & Philosophy Salon.
youtu.be/pP5swFPR0Ns

Prof. Lucina Uddin from UCLA discusses her views on brain networks as studied with functional MRI

YouTube video by Neuroscience & Philosophy Salon

Alessandro Gozzi @gozziale.bsky.social · Dec 9

Very cool result! Congrats! Reminds
of what we found in the rat upon i.v..ghrelin infusion!
👇
pmc.ncbi.nlm.nih.gov/articles/PMC...

Brain Reinforcement System Function is Ghrelin Dependent: Studies in the Rat Using Pharmacological fMRI and Intracranial Self-Stimulation

Ghrelin (GHR) is an orexigenic gut peptide that interacts with brain ghrelin receptors (GHR-Rs) to promote food intake. Recent research suggests that GHR acts as a modulator of motivated behavior, suggesting a direct influence of GHR on brain ...

pmc.ncbi.nlm.nih.gov