Alessandro Gozzi
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gozziale.bsky.social
Alessandro Gozzi
@gozziale.bsky.social

Senior scientist at Istituto Italiano di Tecnologia (Rovereto, Italy)
🧠 🐁 Functional Neuroimaging, Brain (dys)connectivity and Autism
ERC Grantee
https://www.iit.it/it/people-details/-/people/alessandro-gozzi

Neuroscience 77%
Biology 18%
Pinned
Can we use brain scans to identify biologically distinct "autisms"? And If so, how?

In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!

Find out more here 👇👇
www.biorxiv.org/content/10.1...

Thread below 🧵 1/n

Reposted by Alessandro Gozzi

Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons

www.nature.com/articles/s41...
Prediction of neural activity in connectome-constrained recurrent networks - Nature Neuroscience
The authors show that connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictio...
www.nature.com

Reposted by Alessandro Gozzi

ICYMI @ohbmofficial.bsky.social 2025 keynotes are now online! Here's mine: "Towards a universal taxonomy of functional brain networks" 🧠 www.youtube.com/watch?v=ZW9J...
OHBM 2025 | Keynote | Lucina Uddin | Towards a universal taxonomy of functional brain networks
YouTube video by Organization for Human Brain Mapping
www.youtube.com

Great coverage by @thetransmissions.bsky.social of our latest preprint: adding new evidence (and a hint of controversy 🙂) to the E/I imbalance debate in autism
👇👇
www.thetransmitter.org/spectrum/ram...
Ramping up cortical activity in early life sparks autism-like behaviors in mice
The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.
www.thetransmitter.org

Reposted by Alessandro Gozzi

Reposted by Alessandro Gozzi

Job Search
careers.pageuppeople.com

Reposted by Alessandro Gozzi

Talking about spooky stuff…try to do awake mouse fMRI.
Oh, you want it spookier? Try to add simultaneous Ca2+ imaging.

Now, do it all again, longitudinally….

So proud to finally have this out!!!
🐭 🧠 🧲
Go read…if you dare!! 👻

www.biorxiv.org/content/10.1...
Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice
Functional magnetic resonance imaging (fMRI) can be applied in mice and humans making it a key technology in translational neuroimaging research. Yet, most neuroimaging studies in rodents use anesthes...
www.biorxiv.org

Reposted by Alessandro Gozzi

🆕 New open neuroimaging dataset released!

I’m happy to share that our Naturalistic Neuroimaging Database (NNDb3T+) is now publicly available! NNDb3T+ captures rich, multimodal brain activity in a naturalistic setting with 40 participants and over 160 hours of scanning!

Reposted by Alessandro Gozzi

Reposted by Alessandro Gozzi

Interested in the complexity of the brain and the mind? 🧠

Join the School 𝐂𝐨𝐦𝐩𝐥𝐞𝐱𝐢𝐭𝐲 𝐢𝐧 𝐌𝐞𝐧𝐭𝐚𝐥 𝐇𝐞𝐚𝐥𝐭𝐡
📌 Erice, Sicily
📅 26 April–1 May 2026

An #interdisciplinary dialogue on how #mental_states emerge from the #dynamics of 𝐧𝐞𝐮𝐫𝐚𝐥 𝐩𝐫𝐨𝐜𝐞𝐬𝐬𝐞𝐬 and 𝐜𝐨𝐧𝐭𝐞𝐱𝐭𝐮𝐚𝐥 𝐟𝐚𝐜𝐭𝐨𝐫𝐬

centromajorana.it/mentalhealth...
Applications for MCSA are up 64%! 50% now come from outside the EU. Trump effect?

The European Research market just got a hell of a lot more crowded.

EU should turn on the tap

marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...
MSCA Postdoctoral Fellowships 2025 receives record number of 17,058 proposals
This year’s annual MSCA Postdoctoral Fellowships call has attracted considerable interest from the research community with 17,058 proposals submitted.
marie-sklodowska-curie-actions.ec.europa.eu

Reposted by Alessandro Gozzi

🔥🔥 NOOSA Brain Workshop 2026 🔥🔥

Less than 3 weeks left to secure register with accomodation for the Noosa Brain Workshop Feb 23-26, 2026.

Places are filling fast - sign up before November 10!

Details: tinyurl.com/5capskbj

Reposted by Alessandro Gozzi

Is science getting too competitive?

Grant applications are skyrocketing and funding rates are decreasing.

Yet the article in Nature fails to mention the potential role that AI/LLMs in driving up grant applications.

It's becoming a lottery.
www.nature.com/articles/d41...).

Reposted by Alessandro Gozzi

Colombo et al., Plos Biology, "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans"

journals.plos.org/plosbiology/...
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy by disconnecting a significant portion of the cortex. This study shows that the isolated cortex exhibits EEG patterns resem...
journals.plos.org

Reposted by Alessandro Gozzi

Why do brain networks vary? Do these differences shape behavior? If every 🧠 is unique, how can we detect common features of brain organization?
@rodbraga.bsky.social and I dig in, in @annualreviews.bsky.social (ahead of print):
go.illinois.edu/Gratton2025-...

#neuroskyence #psychscisky #MedSky
🧵👇
Dense Phenotyping of Human Brain Network Organization Using Precision fMRI
The advent of noninvasive imaging methods like functional magnetic resonance imaging (fMRI) transformed cognitive neuroscience, providing insights into large-scale brain networks and their link to cog...
go.illinois.edu
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Reposted by Alessandro Gozzi

Delighted to see this out in @NeuroCellPress!!!

Together with Isabel Beerman (& many other friends) we identify disease-associated radial glia-like cells (#DARGs) that fuel #inflammation and #neurodegeneration in #progressiveMS

www.cell.com/neuron/fullt...
Integrated omics reveals disease-associated radial glia-like cells with epigenetically dysregulated interferon response in multiple sclerosis
Park, Nicaise, Tsitsipatis, and colleagues discover transcriptional and epigenetic markers in human PMS iNSCs and fibroblasts that may underlie their senescent and inflammatory state. Novel DARGs with...
www.cell.com

Anytime!! (And thanks!!)

Congrats!!!

Reposted by Alessandro Gozzi

Check out this great summary of our recent paper on the impact of exposure to #THC during gestation.

Thanks @douglasresearch.bsky.social !!

Orig paper here:

www.nature.com/articles/s41...

Reposted by Alessandro Gozzi

🔊We are delighted to announce the appointment of Armin Raznahan as the new WA Handley Professor of Psychiatry.

Professor Raznahan is a child & adolescent psychiatrist, joining us from the US National Institute of Mental Health Intramural Research Program.

More: www.psych.ox.ac.uk/news/armin-r...

Reposted by Alessandro Gozzi

It is now clear that more people are being diagnosed as autistic in their teens and as adults than in childhood. A prevailing theory is that those diagnosed later have "milder" form of autism, and later diagnosis entirely due to social factors.

Reposted by Alessandro Gozzi

Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...

Reposted by Alessandro Gozzi

Our new paper is out now in Neuron! 🎉 With @vaibhavtripathi.bsky.social @maxwellelliott.bsky.social Joanna Ladopoulou, Wendy Sun, Mark Eldaief, and Randy Buckner

Paper link: www.sciencedirect.com/science/arti...

Reposted by Alessandro Gozzi

random neuroimaging question: does anyone in bluesky-land have access to the loadings for neurosynth topics in schaefer 400 (yeo7) space? #neuroskyence @misicbata.bsky.social @richardfbetzel.bsky.social @borismontreal.bsky.social @sofievalk.bsky.social

Reposted by Alessandro Gozzi

The brain is incredibly densely connected. Human cerebral cortex may have as many as *one trillion* connections.

Most of those cortical connections are recurrent, inside each area. What do they do?

New paper from me in Annual Reviews: 🧪 🧠📈 1/

www.annualreviews.org/content/jour...
Active Filtering: A Predictive Function of Recurrent Circuits of Sensory Cortex | Annual Reviews
Our brains encode many features of the sensory world into memories: We can sing along with songs we have heard before, interpret spoken and written language composed of words we have learned, and reco...
www.annualreviews.org

Reposted by Alessandro Gozzi

The Biological Psychiatry family of journals is now officially on Bluesky!

Follow us for the latest research in psychiatric neuroscience, cognitive neuroimaging, and global open science from our three leading journals.

Global brain activity (indexed by Ca2+ in the cortex) can be described by a latent arousal manifold — reliably tracked by pupil dynamics 🤯🤯
▶️ www.nature.com/articles/s41...
Arousal as a universal embedding for spatiotemporal brain dynamics - Nature
Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.
www.nature.com

Reposted by Alessandro Gozzi

Well, well, well. After a long wait, the big day is here!

@kevinh-phd.bsky.social and I finally get to share with you the book we've worked so long and hard on

I wrote a little substack about the question that powered every chapter of Food Intelligence

juliabelluz.substack.com/p/the-big-da...

Congrats!!!