Eiko Fried
@eikofried.bsky.social
Professor of Mental Health & Data Science at Leiden Universuty. Studying mental health problems as systems (http://eiko-fried.com). Building an early warning system for depression (http://WARN-D.com).
Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
BOLD signal changes can oppose oxygen metabolism across the human cortex - Nature Neuroscience
Using quantitative brain imaging, the authors show opposite fMRI BOLD signal to metabolic activity due to variable oxygen extraction across the human cortex. This questions the canonical interpretatio...
www.nature.com
January 5, 2026 at 11:55 AM
Would love to hear expert views on this paper. It appears to show that the operationalization of brain activity the field has relied on for 3 decades—the BOLD response—is not actually a sensible measure of brain activity.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Guardian headline vs small print.
January 4, 2026 at 4:00 AM
Guardian headline vs small print.
Reposted by Eiko Fried
The FIFA Peace prize used to mean something
January 4, 2026 at 2:14 AM
The FIFA Peace prize used to mean something
So anyway, how is your New Years Eve going ..
December 31, 2025 at 7:52 AM
So anyway, how is your New Years Eve going ..
Reposted by Eiko Fried
Today the Swiss announced they don't have an agreement with Springer Nature -- swissuniversity tried to secure a deal and failed in the face of the extreme rise in publishing fees.
When the game is rigged, it's better to stop playing.
🧵 to understand the drain of scientific publishing👇
When the game is rigged, it's better to stop playing.
🧵 to understand the drain of scientific publishing👇
December 22, 2025 at 9:47 PM
Today the Swiss announced they don't have an agreement with Springer Nature -- swissuniversity tried to secure a deal and failed in the face of the extreme rise in publishing fees.
When the game is rigged, it's better to stop playing.
🧵 to understand the drain of scientific publishing👇
When the game is rigged, it's better to stop playing.
🧵 to understand the drain of scientific publishing👇
Reposted by Eiko Fried
Journal article: “the data are available on request”
The data:
The data:
December 20, 2025 at 11:33 AM
Journal article: “the data are available on request”
The data:
The data:
Reposted by Eiko Fried
This smells distinctly like collider bias and/or selection bias and/or regression to the mean... You simply can't select teen prodigies, and world class athletes rom databases, and go run regressions without serious consideration of the selection process!
"Most top achievers (Nobel laureates and world-class musicians, athletes, chess players) demonstrated lower performance than many peers during their early years. Across the highest adult performance, peak performance is negatively correlated with early performance" www.science.org/doi/10.1126/...
Recent discoveries on the acquisition of the highest levels of human performance
Scientists have long debated the origins of exceptional human achievements. This literature review summarizes recent evidence from multiple domains on the acquisition of world-class performance. We re...
www.science.org
December 20, 2025 at 3:48 PM
This smells distinctly like collider bias and/or selection bias and/or regression to the mean... You simply can't select teen prodigies, and world class athletes rom databases, and go run regressions without serious consideration of the selection process!
Our university press team asked me a few questions in regards to the new chair on Mental Health & Data Science. I sketch a bit of a vision on the importance of transdisciplinary work, and some obstacles to overcome.
www.universiteitleiden.nl/en/news/2025...
www.universiteitleiden.nl/en/news/2025...
Transdisciplinary work is fantastic, but requires dedicated efforts from all sides to understand each other’
Eiko Fried has been appointed professor of Mental Health & Data Science. This combined chair neatly fits the view that understanding complex mental health issues require the integration of statistical...
www.universiteitleiden.nl
December 19, 2025 at 8:18 AM
Our university press team asked me a few questions in regards to the new chair on Mental Health & Data Science. I sketch a bit of a vision on the importance of transdisciplinary work, and some obstacles to overcome.
www.universiteitleiden.nl/en/news/2025...
www.universiteitleiden.nl/en/news/2025...
Reposted by Eiko Fried
I've used Lavaan almost every (work)day for 15 years, but this open source labour of love has never received proper institutional support. I'm delighted to be a small part of an 1.5M OpenScienceNL award, led by Jorgensen, to completely revamp and futureproof Lavaan www.openscience.nl/en/news/45-p...
December 18, 2025 at 7:44 AM
I've used Lavaan almost every (work)day for 15 years, but this open source labour of love has never received proper institutional support. I'm delighted to be a small part of an 1.5M OpenScienceNL award, led by Jorgensen, to completely revamp and futureproof Lavaan www.openscience.nl/en/news/45-p...
Reposted by Eiko Fried
Nice writeup of our new study in @jamapsychiatry.com by Kyle Mittan, a colleague here at @uarizona.bsky.social
news.arizona.edu/news/confuse...
news.arizona.edu/news/confuse...
December 17, 2025 at 5:13 PM
Nice writeup of our new study in @jamapsychiatry.com by Kyle Mittan, a colleague here at @uarizona.bsky.social
news.arizona.edu/news/confuse...
news.arizona.edu/news/confuse...
Reposted by Eiko Fried
1/n Out today in @jamapsychiatry.com: Interpretation Issues With the Patient Health Questionnaire Instructions. We find troubling variability in whether people think they should respond based on the frequency of the Sx or the frequency of being bothered by the Sx.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Interpretation Issues With the Patient Health Questionnaire Instructions
This survey study assesses whether responses to the Patient Health Questionnaire reflect symptom frequency and severity.
jamanetwork.com
December 17, 2025 at 5:11 PM
1/n Out today in @jamapsychiatry.com: Interpretation Issues With the Patient Health Questionnaire Instructions. We find troubling variability in whether people think they should respond based on the frequency of the Sx or the frequency of being bothered by the Sx.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Thanks @janhove.bsky.social for taking the time to check the paper — something that paid editors at Nature, as well as unpaid reviewers — apparently did not.
Also shows once more that providing statistical code should be mandatory for every single paper.
janhove.github.io/posts/2025-1...
Also shows once more that providing statistical code should be mandatory for every single paper.
janhove.github.io/posts/2025-1...
Jan Vanhove :: Blog - Does multilingualism really protect against accelerated ageing? Some critical comments
janhove.github.io
December 17, 2025 at 10:28 AM
Thanks @janhove.bsky.social for taking the time to check the paper — something that paid editors at Nature, as well as unpaid reviewers — apparently did not.
Also shows once more that providing statistical code should be mandatory for every single paper.
janhove.github.io/posts/2025-1...
Also shows once more that providing statistical code should be mandatory for every single paper.
janhove.github.io/posts/2025-1...
Reposted by Eiko Fried
You remember that Nature Aging paper about how multilingualism protects against accelerated aging? Well…
December 17, 2025 at 7:15 AM
You remember that Nature Aging paper about how multilingualism protects against accelerated aging? Well…
Reposted by Eiko Fried
Critique argues post-publication peer review "often focuses on minor details" and "risks damaging trust in both the research itself and the peer review process" found to contain:
- Hallucinated references
- Undisclosed COIs (EiC is author)
- 8/9 authors have retractions or related scandals
- Hallucinated references
- Undisclosed COIs (EiC is author)
- 8/9 authors have retractions or related scandals
An expert criticism on post-publication peer review platforms: the case of pubpeer - DARU Journal of Pharmaceutical Sciences
While traditional peer review offers advantages in academic publishing, it is often hampered by significant weaknesses, leading to frustration among many authors. Scientific discoveries after publicat...
link.springer.com
December 13, 2025 at 12:12 PM
Critique argues post-publication peer review "often focuses on minor details" and "risks damaging trust in both the research itself and the peer review process" found to contain:
- Hallucinated references
- Undisclosed COIs (EiC is author)
- 8/9 authors have retractions or related scandals
- Hallucinated references
- Undisclosed COIs (EiC is author)
- 8/9 authors have retractions or related scandals
Our new paper "Inconsistent outcome measurement in depression psychotherapy trials: A systematic historical and meta-analytic review over the past 50 years" led by @antoniasprenger.bsky.social is out now in JAD.
🧪 #PsychSciSky
www.sciencedirect.com/science/arti...
🧪 #PsychSciSky
www.sciencedirect.com/science/arti...
December 11, 2025 at 12:06 AM
Our new paper "Inconsistent outcome measurement in depression psychotherapy trials: A systematic historical and meta-analytic review over the past 50 years" led by @antoniasprenger.bsky.social is out now in JAD.
🧪 #PsychSciSky
www.sciencedirect.com/science/arti...
🧪 #PsychSciSky
www.sciencedirect.com/science/arti...
New preregistered preprint by @emkbridger.bsky.social (w J Maltby, @danielnettle.bsky.social & @larsklintwall.bsky.social). We queried a UK-representative lay sample to rated perceived causal influence between 20 biopsychosocial causes linked to mental health & poverty.
osf.io/preprints/ps...
osf.io/preprints/ps...
December 11, 2025 at 12:02 AM
New preregistered preprint by @emkbridger.bsky.social (w J Maltby, @danielnettle.bsky.social & @larsklintwall.bsky.social). We queried a UK-representative lay sample to rated perceived causal influence between 20 biopsychosocial causes linked to mental health & poverty.
osf.io/preprints/ps...
osf.io/preprints/ps...
Reposted by Eiko Fried
are we still on about em dashes and ai. imo human writers should just use the em dashes even harder. we should be out here pummeling out those em dashes like we're emily dickinson
December 10, 2025 at 3:22 AM
are we still on about em dashes and ai. imo human writers should just use the em dashes even harder. we should be out here pummeling out those em dashes like we're emily dickinson
Reposted by Eiko Fried
We’re excited to share that Prof. Eiko Fried (@eikofried.bsky.social) will give a keynote titled “Measuring minds in motion: pitfalls and promises of AA methods in mental health science” at #SAA2026 in Vienna! We look forward to the perspectives he’ll bring to the programme.
December 9, 2025 at 12:07 PM
We’re excited to share that Prof. Eiko Fried (@eikofried.bsky.social) will give a keynote titled “Measuring minds in motion: pitfalls and promises of AA methods in mental health science” at #SAA2026 in Vienna! We look forward to the perspectives he’ll bring to the programme.
Awesome preprint on model checking for VAR Models. Would love to see more "model checking" tutorial papers for various models, including a showcase what happens if the assumptions you impose on your data are not met in the data.
🧪 #psychscisky
osf.io/preprints/ps...
🧪 #psychscisky
osf.io/preprints/ps...
OSF
osf.io
December 9, 2025 at 1:39 AM
Awesome preprint on model checking for VAR Models. Would love to see more "model checking" tutorial papers for various models, including a showcase what happens if the assumptions you impose on your data are not met in the data.
🧪 #psychscisky
osf.io/preprints/ps...
🧪 #psychscisky
osf.io/preprints/ps...
Retracted Scientific Reports (Nature Group) paper entitled "Bridging the gap: explainable ai for autism diagnosis and parental support".
Imagine how many people at a journal need to not do their job at all (editor, reviewers, copy editor) for this to get published...
Imagine how many people at a journal need to not do their job at all (editor, reviewers, copy editor) for this to get published...
Hey sorry for responding only now :) And thanks for asking for my opinion!!
So look. I'll be honest. This style right now is hated, and for a reason - see for example this slop fake paper that got published in Nature (!!), then retracted (a separate problem of course)
www.nature.com/articles/s41...
So look. I'll be honest. This style right now is hated, and for a reason - see for example this slop fake paper that got published in Nature (!!), then retracted (a separate problem of course)
www.nature.com/articles/s41...
December 9, 2025 at 1:24 AM
Retracted Scientific Reports (Nature Group) paper entitled "Bridging the gap: explainable ai for autism diagnosis and parental support".
Imagine how many people at a journal need to not do their job at all (editor, reviewers, copy editor) for this to get published...
Imagine how many people at a journal need to not do their job at all (editor, reviewers, copy editor) for this to get published...
Looks like Australia's social media ban came into effect. Age verification appears based on 1) facial scan age estimation or 2) ID scan. This in turn appears to be done by third party companies, so opens doors to privacy issues / leaks.
Also, what exactly was the evidence base for this ban again?
Also, what exactly was the evidence base for this ban again?
December 9, 2025 at 1:16 AM
Looks like Australia's social media ban came into effect. Age verification appears based on 1) facial scan age estimation or 2) ID scan. This in turn appears to be done by third party companies, so opens doors to privacy issues / leaks.
Also, what exactly was the evidence base for this ban again?
Also, what exactly was the evidence base for this ban again?
I wonder how much quicker papers would be rejected or published on average if journal software would forward out of office responses of contacted reviewers to handling editors — something that requires advanced software available since ... *checks* ... the 90s.
December 6, 2025 at 4:08 AM
I wonder how much quicker papers would be rejected or published on average if journal software would forward out of office responses of contacted reviewers to handling editors — something that requires advanced software available since ... *checks* ... the 90s.
Reposted by Eiko Fried
Excited to share a Registered Report in J. of Personality looking at the “perils of partialing” – led by the Bluesky-less Leigha Rose with @drlynam.bsky.social and me. (1)
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Perils of Partialing: Can Scholars Predict Residualized Variables' Nomological Nets?
Objective Partialing is a statistical procedure in which the variance shared among two or more constructs is removed, allowing researchers to examine the unique properties of the residualized, parti...
onlinelibrary.wiley.com
December 4, 2025 at 5:07 PM
Excited to share a Registered Report in J. of Personality looking at the “perils of partialing” – led by the Bluesky-less Leigha Rose with @drlynam.bsky.social and me. (1)
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Eiko Fried
Diederik Stapel was a massive watershed moment in psychology.
However, he was -- and let's be slightly glib here -- some guy from The Netherlands who wrote social psychology papers.
The full accounting of the Eysenck case is approx, at minimum, TWO STAPELS.
retractionwatch.com/2025/12/03/n...
However, he was -- and let's be slightly glib here -- some guy from The Netherlands who wrote social psychology papers.
The full accounting of the Eysenck case is approx, at minimum, TWO STAPELS.
retractionwatch.com/2025/12/03/n...
Number of ‘unsafe’ publications by psychologist Hans Eysenck could be ‘high and far reaching’
Hans Eysenck A “high and far reaching” number of papers and books by Hans Eysenck could be “unsafe,” according to an updated statement from King’s College London, where the psychologist was a profe…
retractionwatch.com
December 3, 2025 at 5:34 PM
Diederik Stapel was a massive watershed moment in psychology.
However, he was -- and let's be slightly glib here -- some guy from The Netherlands who wrote social psychology papers.
The full accounting of the Eysenck case is approx, at minimum, TWO STAPELS.
retractionwatch.com/2025/12/03/n...
However, he was -- and let's be slightly glib here -- some guy from The Netherlands who wrote social psychology papers.
The full accounting of the Eysenck case is approx, at minimum, TWO STAPELS.
retractionwatch.com/2025/12/03/n...