Alex Shackman
@ajshackman.bsky.social
Laboratory for Affective & Translational Neuroscience, University of Maryland | shackmanlab.org | affective neuroscience | "pessimism of the intellect, optimism of the will.”
A prospective biomarker-guided precision medicine
trial of bupropion and sertraline for major
depressive disorder: Sequential Multiple
Assignment Randomized Trial in Depression
(SMART-D)
www.researchsquare.com/article/rs-8...
trial of bupropion and sertraline for major
depressive disorder: Sequential Multiple
Assignment Randomized Trial in Depression
(SMART-D)
www.researchsquare.com/article/rs-8...
A prospective biomarker-guided precision medicine trial of bupropion and sertraline for major depressive disorder: Sequential Multiple Assignment Randomized Trial in Depression (SMART-D)
Treatment for major depressive disorder (MDD) remains challenging as only 30% of patients respond to antidepressants in primary care. Here, we developed algorithms using predictors of response to sert...
www.researchsquare.com
January 2, 2026 at 4:22 PM
A prospective biomarker-guided precision medicine
trial of bupropion and sertraline for major
depressive disorder: Sequential Multiple
Assignment Randomized Trial in Depression
(SMART-D)
www.researchsquare.com/article/rs-8...
trial of bupropion and sertraline for major
depressive disorder: Sequential Multiple
Assignment Randomized Trial in Depression
(SMART-D)
www.researchsquare.com/article/rs-8...
Reposted by Alex Shackman
Happy New Year everyone!
January 1, 2026 at 9:09 AM
Happy New Year everyone!
Agreed.
For 2026, I dare the human & rodent behavioral & cognitive neuroscience communities to find one NHP paper relevant to your research & cite it regularly next year when writing up your manuscripts. If you already cite one, find another one and double up. #Neuroskyence bsky.app/profile/vinc...
I definitely didn’t just scrape the web to get the h-index and total citation count as of 12/30/2025 for 319 living and dead nonhuman primate researchers to get a sense of publication metrics by rank on tenure-track.
December 31, 2025 at 9:09 PM
Agreed.
Reposted by Alex Shackman
Example 2: Hegseth did not want detailed updates of the conditions of the war - nothing more than 4-5 sentences
December 31, 2025 at 2:36 PM
Example 2: Hegseth did not want detailed updates of the conditions of the war - nothing more than 4-5 sentences
3,100 miles on the bike this year!
December 31, 2025 at 5:34 PM
3,100 miles on the bike this year!
Shingles vax FTW. Getting mine Sunday... substack.com/@erictopol/n...
Eric Topol (@erictopol)
Multiple large natural experiments have documented Shingles vaccine is linked with ~20-25% reduced risk of dementia and Alzheimer's disease. A new report today adds to that and extends the to slowing...
substack.com
December 31, 2025 at 5:32 PM
Shingles vax FTW. Getting mine Sunday... substack.com/@erictopol/n...
Based on a quick skim, this is great... www.thelancet.com/journals/lan...
Implementing lifestyle interventions in mental health care: third report of the Lancet Psychiatry Physical Health Commission
The physical health disparities experienced by people who live with mental illness
are well documented. This population group has cardiometabolic risks and diseases
at rates 1·4–2·0 times higher than ...
www.thelancet.com
December 30, 2025 at 4:04 PM
Based on a quick skim, this is great... www.thelancet.com/journals/lan...
good explanation
December 30, 2025 at 1:08 PM
good explanation
Reposted by Alex Shackman
some mornings you wake up and your brain is ready to seize the day and then other mornings you wake up and your brain forces you to think something like “I bet Alf’s favorite band is Spacehog”
December 27, 2025 at 5:31 PM
some mornings you wake up and your brain is ready to seize the day and then other mornings you wake up and your brain forces you to think something like “I bet Alf’s favorite band is Spacehog”
www.paradromics.com/blog/bci-ben... Cool examples
Think Fast | Setting new standards and new records for brain-computer interfaces
Paradromics Connexus BCI sets new records with the SONIC benchmark, achieving 200+ bps and low latency, defining a new standard for BCIs.
www.paradromics.com
December 26, 2025 at 2:24 PM
www.paradromics.com/blog/bci-ben... Cool examples
Cristello...& Scholars for Elevating Equity and Diversity (SEED). (2025). Reconsidering research experiences as admission criteria for clinical psychology and clinical science PhD programs. Training and Education in Professional Psychology, 19(4), 286–291. doi.org/10.1037/tep0...
APA PsycNet
doi.org
December 25, 2025 at 7:08 PM
Cristello...& Scholars for Elevating Equity and Diversity (SEED). (2025). Reconsidering research experiences as admission criteria for clinical psychology and clinical science PhD programs. Training and Education in Professional Psychology, 19(4), 286–291. doi.org/10.1037/tep0...
Reposted by Alex Shackman
Happy Birthday NMR. NMR turns 80 today. It’s the gift that keeps on giving because of it’s infinite flexibility.
And Happy Birthday baby Jesus as well to those who celebrate.
And Happy Birthday baby Jesus as well to those who celebrate.
[December 24th, 1945] Edward M. Purcell, with colleagues Henry C. Torrey and Robert V. Pound at Harvard, had their paper accepted by the American Physical Society, detailing their discovery of Nuclear Magnetic Resonance (NMR), a breakthrough that uses magnetic fields to probe atomic nuclei,
December 24, 2025 at 4:12 PM
Happy Birthday NMR. NMR turns 80 today. It’s the gift that keeps on giving because of it’s infinite flexibility.
And Happy Birthday baby Jesus as well to those who celebrate.
And Happy Birthday baby Jesus as well to those who celebrate.
LaFreniere, L. S., & Newman, M. G. (2023). Upregulating positive emotion in generalized anxiety disorder: A randomized controlled trial of the SkillJoy ecological momentary intervention. Journal of Consulting and Clinical Psychology, 91(6), 381–387. doi.org/10.1037/ccp0...
APA PsycNet
doi.org
December 22, 2025 at 7:34 PM
LaFreniere, L. S., & Newman, M. G. (2023). Upregulating positive emotion in generalized anxiety disorder: A randomized controlled trial of the SkillJoy ecological momentary intervention. Journal of Consulting and Clinical Psychology, 91(6), 381–387. doi.org/10.1037/ccp0...
