Jordan Shivers
@jordanlshivers.bsky.social
Schmidt AI in Science Postdoctoral Fellow at U. Chicago
theoretical & computational soft matter, biophysics, machine learning
jordanshivers.github.io
theoretical & computational soft matter, biophysics, machine learning
jordanshivers.github.io
Reposted by Jordan Shivers
The long-awaited Dipids paper is finally out www.nature.com/articles/s41...! Check out the largest containers ever self-assembled from DNA origami🧬, and the amazing person and story behind it www.linkedin.com/feed/update/... Congrats to Christoph🎉 and thanks for letting me be part of this journey🥹!
Self-assembled cell-scale containers made from DNA origami membranes - Nature Materials
Through the programmable self-assembly of lipid-inspired radially symmetric DNA, porous molecular membranes and cell-sized compartments are formed with applications in bottom-up biology and soft robot...
www.nature.com
November 28, 2025 at 3:32 PM
The long-awaited Dipids paper is finally out www.nature.com/articles/s41...! Check out the largest containers ever self-assembled from DNA origami🧬, and the amazing person and story behind it www.linkedin.com/feed/update/... Congrats to Christoph🎉 and thanks for letting me be part of this journey🥹!
Reposted by Jordan Shivers
Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza @weillinstitute.bsky.social
November 25, 2025 at 1:36 AM
Motivational video for #MigrationMovieMonday. A persistent 4T1 breast cancer cell squeezing itself through a tight constriction despite undergoing repetitive nuclear envelope rupture. Credit: Kristen Nedza @weillinstitute.bsky.social
Reposted by Jordan Shivers
📢 Paper alert 📢
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
November 24, 2025 at 5:50 PM
📢 Paper alert 📢
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
Chirality is known to be important for the movement of microorganisms and active matter. In our new paper out today in @natphys.nature.com, we show that chirality is used by malaria parasites to control their motion patterns:
doi.org/10.1038/s415...
Here comes a 🧵 ... (1/9)
Reposted by Jordan Shivers
Synchronized development of zebrafish embryos immobilized by snake venom (alpha-bungarotoxin). Credit to Dr. Ian Swinburne. #ZebrafishZunday
November 23, 2025 at 12:12 PM
Synchronized development of zebrafish embryos immobilized by snake venom (alpha-bungarotoxin). Credit to Dr. Ian Swinburne. #ZebrafishZunday
Reposted by Jordan Shivers
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
November 23, 2025 at 3:21 AM
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Reposted by Jordan Shivers
Cellular structure self-organizes through an interplay between internal mechanisms and external cues. The single-celled suctorian P. collini builds a trap structure to capture large prey using microtubule feeding tentacles, creating feedback between cell morphology and prey availability.
November 18, 2025 at 4:15 PM
Cellular structure self-organizes through an interplay between internal mechanisms and external cues. The single-celled suctorian P. collini builds a trap structure to capture large prey using microtubule feeding tentacles, creating feedback between cell morphology and prey availability.
Reposted by Jordan Shivers
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
November 21, 2025 at 1:07 PM
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Reposted by Jordan Shivers
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
November 14, 2025 at 8:38 PM
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
Reposted by Jordan Shivers
Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and #migrasomes. New study from Peiyao Fan, Yang Chen and colleagues @pku1898.bsky.social: rupress.org/jcb/article/...
#Migration #motility #Biochemistry #Organelles #ER_literature
#Migration #motility #Biochemistry #Organelles #ER_literature
November 13, 2025 at 2:45 PM
Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and #migrasomes. New study from Peiyao Fan, Yang Chen and colleagues @pku1898.bsky.social: rupress.org/jcb/article/...
#Migration #motility #Biochemistry #Organelles #ER_literature
#Migration #motility #Biochemistry #Organelles #ER_literature
Reposted by Jordan Shivers
Ten years ago, I saw a paper with some data that has bothered me ever since: B cells in a 0-100 ng/mL gradient of CCL19 are attracted to CCL19, but B cells in 0-500 ng/mL are repelled (see movie, ignoring the big clusters for now!). Why? Here's our model! doi.org/10.1101/2025...
October 30, 2025 at 5:32 PM
Ten years ago, I saw a paper with some data that has bothered me ever since: B cells in a 0-100 ng/mL gradient of CCL19 are attracted to CCL19, but B cells in 0-500 ng/mL are repelled (see movie, ignoring the big clusters for now!). Why? Here's our model! doi.org/10.1101/2025...
Reposted by Jordan Shivers
Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost!
PNAS www.pnas.org/doi/10.1073/...
PNAS www.pnas.org/doi/10.1073/...
November 11, 2025 at 11:01 PM
Just out! Our work on active transport in epithelial tissues. Congrats to Huiqiong Wu, Greg Arkowitz and Ranjith Chilupuri in collaboration with C. Duclut and J. Prost!
PNAS www.pnas.org/doi/10.1073/...
PNAS www.pnas.org/doi/10.1073/...
Reposted by Jordan Shivers
Systematic membrane thickness variation across cellular #organelles revealed by cryo-ET. New computational workflow developed by Desislava Glushkova (@deglushk.bsky.social), Stefanie Böhm, & Martin Beck (@becklab.bsky.social) @mpibp.bsky.social: rupress.org/jcb/article/...
#StructuralBiology #Golgi
#StructuralBiology #Golgi
November 11, 2025 at 2:45 PM
Systematic membrane thickness variation across cellular #organelles revealed by cryo-ET. New computational workflow developed by Desislava Glushkova (@deglushk.bsky.social), Stefanie Böhm, & Martin Beck (@becklab.bsky.social) @mpibp.bsky.social: rupress.org/jcb/article/...
#StructuralBiology #Golgi
#StructuralBiology #Golgi
Reposted by Jordan Shivers
Membrane blebs on a cancer cell videoed through a DIC microscope. What are blebs? Intracellular pressure within the cell blowing up tiny balloons using the plasma membrane. Or something like that. #CellBiology
November 11, 2025 at 3:01 AM
Membrane blebs on a cancer cell videoed through a DIC microscope. What are blebs? Intracellular pressure within the cell blowing up tiny balloons using the plasma membrane. Or something like that. #CellBiology
Reposted by Jordan Shivers
I had the privilege of giving Science Saturday, an engaging public lecture meant to spark curiosity about the wonders of science. My talk, “The Physics of Mysterious Droplets,” explored liquid-like droplets inside our cells and the physics behind their behavior: www.youtube.com/watch?v=5R16...
The Physics of Mysterious Cellular Droplets
YouTube video by WU Physics Department
www.youtube.com
November 11, 2025 at 12:16 AM
I had the privilege of giving Science Saturday, an engaging public lecture meant to spark curiosity about the wonders of science. My talk, “The Physics of Mysterious Droplets,” explored liquid-like droplets inside our cells and the physics behind their behavior: www.youtube.com/watch?v=5R16...
Reposted by Jordan Shivers
Get into flow with zebrafish — soon your eyes will glow 🐟✨
Blood flow in a transparent zebrafish embryo. Credit to @damiandn.bsky.social. #ZebrafishZunday 🧪
November 9, 2025 at 12:06 PM
Get into flow with zebrafish — soon your eyes will glow 🐟✨
Reposted by Jordan Shivers
Beating iPSC-derived heart muscle cells videoed through a microscope. Alpha-actinin-2 is shown. #CellBiology
November 9, 2025 at 3:12 AM
Beating iPSC-derived heart muscle cells videoed through a microscope. Alpha-actinin-2 is shown. #CellBiology
Reposted by Jordan Shivers
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
November 7, 2025 at 11:02 AM
We have wondered what a complex archaeal cell might look like ever since 2014. It’s been a long road (and the journey is far from over), but it’s a good time to pause for breath and look. These Asgard archaeal cells are a surprise! And that is the joy of being a cell biologist.
Reposted by Jordan Shivers
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Reposted by Jordan Shivers
Now online! Disparate leukemia mutations converge on nuclear phase-separated condensates
Disparate leukemia mutations converge on nuclear phase-separated condensates
Mutant NPM1 and various leukemia oncofusions form biophysically indistingishable nuclear condensates, termed C-bodies, which orchestrate leukemogenic gene expression. These findings consolidate diverse genetic lesions into a shared pathogenic mechanism in AML.
dlvr.it
November 4, 2025 at 7:51 PM
Now online! Disparate leukemia mutations converge on nuclear phase-separated condensates
Reposted by Jordan Shivers
HL60 cells take on so many fun shapes as they migrate! This #InsightFromImaging data features cells prepared by Leanna and imaged on the @aicjanelia.bsky.social LLSM by @cmhobson.bsky.social
November 4, 2025 at 10:36 PM
HL60 cells take on so many fun shapes as they migrate! This #InsightFromImaging data features cells prepared by Leanna and imaged on the @aicjanelia.bsky.social LLSM by @cmhobson.bsky.social
Reposted by Jordan Shivers
Soft corals switch between flexible and rigid states by jamming together or pulling apart branched skeletal structures suspended in gel. A study explores the shapes of the structures, called sclerites, with implications for soft robotics. In PNAS: https://ow.ly/rRgI50XlMmA
November 4, 2025 at 12:00 AM
Soft corals switch between flexible and rigid states by jamming together or pulling apart branched skeletal structures suspended in gel. A study explores the shapes of the structures, called sclerites, with implications for soft robotics. In PNAS: https://ow.ly/rRgI50XlMmA
Reposted by Jordan Shivers
🎉🎉 We finally have a website! 🎉🎉
Did you miss a thread?
Want to know who our delegates are?
Do you want to join our big club?
Check it out:
epithelialmechanics.github.io
Huge thanks to all thread-contributors and to you for following us!
Did you miss a thread?
Want to know who our delegates are?
Do you want to join our big club?
Check it out:
epithelialmechanics.github.io
Huge thanks to all thread-contributors and to you for following us!
Epithelial Mechanics Fan Club
epithelialmechanics.github.io
October 23, 2025 at 7:00 AM
🎉🎉 We finally have a website! 🎉🎉
Did you miss a thread?
Want to know who our delegates are?
Do you want to join our big club?
Check it out:
epithelialmechanics.github.io
Huge thanks to all thread-contributors and to you for following us!
Did you miss a thread?
Want to know who our delegates are?
Do you want to join our big club?
Check it out:
epithelialmechanics.github.io
Huge thanks to all thread-contributors and to you for following us!
Reposted by Jordan Shivers
And now… part two of our twin papers on how chromosomes find their place before division! Led by @krunovuk.bsky.social at @institutrb.bsky.social, out in @natcomms.nature.com!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
October 29, 2025 at 5:09 PM
And now… part two of our twin papers on how chromosomes find their place before division! Led by @krunovuk.bsky.social at @institutrb.bsky.social, out in @natcomms.nature.com!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
Reposted by Jordan Shivers
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Reposted by Jordan Shivers
Hot out of press!!!
Studying chloroplast organisation from the perspective of packing problems in confinement.
chloroplasts show multiple configurations for different purposes (optimal light uptake in dim light vs. light avoidance in strong light for photo protection)🌿
www.pnas.org/doi/10.1073/...
Studying chloroplast organisation from the perspective of packing problems in confinement.
chloroplasts show multiple configurations for different purposes (optimal light uptake in dim light vs. light avoidance in strong light for photo protection)🌿
www.pnas.org/doi/10.1073/...
Optimal disk packing of chloroplasts in plant cells | PNAS
Photosynthesis is essential for ecosystem survival, but while plants require light,
excessive exposure can damage cells. Chloroplasts, photosynthet...
www.pnas.org
October 27, 2025 at 8:14 AM
Hot out of press!!!
Studying chloroplast organisation from the perspective of packing problems in confinement.
chloroplasts show multiple configurations for different purposes (optimal light uptake in dim light vs. light avoidance in strong light for photo protection)🌿
www.pnas.org/doi/10.1073/...
Studying chloroplast organisation from the perspective of packing problems in confinement.
chloroplasts show multiple configurations for different purposes (optimal light uptake in dim light vs. light avoidance in strong light for photo protection)🌿
www.pnas.org/doi/10.1073/...