Iva Tolić
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ivatolic.bsky.social
Iva Tolić
@ivatolic.bsky.social
Biophysics of mitosis / mitotic spindle / chromosome segregation and aneuploidy
Head of Laboratory of Cell Biophysics at @institutrb.bsky.social, previously at @mpi-cbg.de, LENS Florence, Niels Bohr Institute, @hsph.harvard.edu, Uni Zagreb.
tolic.irb.hr
A golden Zagreb morning before work
October 31, 2025 at 8:47 PM
And now… part two of our twin papers on how chromosomes find their place before division! Led by @krunovuk.bsky.social at @institutrb.bsky.social, out in @natcomms.nature.com!

doi.org/10.1038/s414...
doi.org/10.1038/s414...

Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
October 29, 2025 at 5:09 PM
Two back-to-back stories on mitosis led by my incredible postdoc @krunovuk.bsky.social at @institutrb.bsky.social, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in @natcomms.nature.com
doi.org/10.1038/s414...
doi.org/10.1038/s414...
October 21, 2025 at 11:14 AM
Reposted by Iva Tolić
#Mifobio2025

Focus on the module 5:
👉 Physical measurements, control and handling -Mechanobiology

We are delighted to welcome Professor @ivatolic.bsky.social
Ruđer Bošković Institute

Lecture : “Mechanobiology of the Mitotic Spindle”

👉 imabio-cnrs.fr

#GDRimabio #microscopy #biological_imaging
October 5, 2025 at 3:58 PM
Reposted by Iva Tolić
🔬For 22 years, we have been organizing #Mifobio "Functional Microscopy for Biology" the @cnrs.fr thematic school.

🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.

👉 Program: imabio-cnrs.fr

#GDRImaBio #Mifobio2025
October 3, 2025 at 10:45 PM
Reposted by Iva Tolić
Delighted to share our latest work showing how cells that evade #senescence after CDK4/6 inhibition are primed to become aneuploid because of their increased size (due to defects in cohesion and the mitotic checkpoint). Great work by fab PhD student Aanchal Pareri 👏🧪

www.biorxiv.org/content/10.1...
Cell enlargement causes mitotic errors and aneuploidy in cells that evade senescence after CDK4/6 inhibition
CDK4/6 inhibitors (CDK4/6i) arrest the cell cycle in G1 leading to cellular overgrowth and p53-dependent senescence. They are used to treat metastatic HR+/HER2- breast cancer, but resistance is common...
www.biorxiv.org
July 3, 2025 at 7:17 AM
Amazing energy at our second Swiss-Croatian Bilateral Project meeting with @labmeraldi.bsky.social and Pavin Group in Srebreno near Dubrovnik! The labs teamed up instantly, with lots of brainstorming and cool ideas for new joint projects! #HRZZ @snsf-ch.bsky.social
🇭🇷🇨🇭
April 26, 2025 at 9:22 AM
Great memories from the joint meeting with the Meraldi Lab and Pavin Group last year in Split! Can't wait for this year's meeting, which starts tomorrow! Excited for more cool science through our Swiss-Croatian Bilateral Project #HRZZ @snsf-ch.bsky.social 🇭🇷🇨🇭
April 8, 2025 at 6:29 AM
Perfect for PhD students and postdocs! www.atoutcom.com/shaping-life...
March 21, 2025 at 12:54 PM
Happy first day of spring from our Institute @institutrb.bsky.social!
March 20, 2025 at 8:52 PM
Join us for this small, intensive workshop in the remote Alpine town of Arolla, where we will explore the dynamics of living systems across scales, from the cytoskeleton to embryos. Let’s dive into how cellular and tissue-scale dynamics shape life itself! meetings.ls2.ch/arolla2025
March 16, 2025 at 6:38 PM
Reposted by Iva Tolić
Introducing blebbisomes! Cover art by @ento-sanchez.bsky.social! #CellBiology
Article: www.nature.com/articles/s41...
March 15, 2025 at 1:48 PM
🚀Ever wondered if there's a universal rule of spindle scaling across eukaryotes? Turns out, there is! Our study reveals an evolutionarily conserved principle driven by a surprising factor: chromosome crowding. 🧵👇
shorturl.at/MmPNr
March 10, 2025 at 4:25 PM
Happy Women’s Day to all the amazing women out there! Special congrats to two incredible young scientists from my lab, Valentina Štimac & Isabella Koprivec, who earned their PhDs last year! 💡 And a spotlight on Valentina for winning the L'Oréal-UNESCO For Women in Science award! 🔥 #WomeninSTEM
March 8, 2025 at 6:31 PM