Iva Tolić
@ivatolic.bsky.social
Biophysics of mitosis / mitotic spindle / chromosome segregation and aneuploidy
Head of Laboratory of Cell Biophysics at @institutrb.bsky.social, previously at @mpi-cbg.de, LENS Florence, Niels Bohr Institute, @hsph.harvard.edu, Uni Zagreb.
tolic.irb.hr
Head of Laboratory of Cell Biophysics at @institutrb.bsky.social, previously at @mpi-cbg.de, LENS Florence, Niels Bohr Institute, @hsph.harvard.edu, Uni Zagreb.
tolic.irb.hr
Mitosis lovers, get ready for Dubrovnik! 🔬🎉
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026
February 2, 2026 at 8:22 AM
Mitosis lovers, get ready for Dubrovnik! 🔬🎉
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026
PhD position in my lab!
January 28, 2026 at 5:25 PM
PhD position in my lab!
Thanks, @focalplane.bsky.social!
🔬🔦Our latest imaging spotlight is from Kruno Vukušić @krunovuk.bsky.social & Iva Tolić @ivatolic.bsky.social, describing their research using multi-scale live lattice light-sheet microscopy & super-resolution microscopy to interrogate the earliest steps of chromosome congression.
Imaging spotlight: Initiation of chromosome congression deconstructed by multi-scale live lattice light-sheet and super-resolution microscopy - FocalPlane
Imaging spotlight: Initiation of chromosome congression deconstructed by multi-scale live lattice light-sheet and super-resolution microscopy - News
focalplane.biologists.com
January 21, 2026 at 1:50 PM
Thanks, @focalplane.bsky.social!
National ERC Information Day in Zagreb! Together with other ERC panel members, we shared what happens behind closed panel doors, and with fellow ERC Synergy grantees, I talked about the full journey from the first idea to a funded grant. @erc.europa.eu
link.europa.eu/dXQmbr
link.europa.eu/dXQmbr
December 13, 2025 at 10:25 AM
National ERC Information Day in Zagreb! Together with other ERC panel members, we shared what happens behind closed panel doors, and with fellow ERC Synergy grantees, I talked about the full journey from the first idea to a funded grant. @erc.europa.eu
link.europa.eu/dXQmbr
link.europa.eu/dXQmbr
Reposted by Iva Tolić
Reappraisal of motor protein CENPE's role in bringing chromosomes together in preparation for accurate cell division
📷 @krunovuk.bsky.social & @ivatolic.bsky.social @institutrb.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025... with
John Ankers
📷 @krunovuk.bsky.social & @ivatolic.bsky.social @institutrb.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025... with
John Ankers
December 12, 2025 at 10:35 AM
Reappraisal of motor protein CENPE's role in bringing chromosomes together in preparation for accurate cell division
📷 @krunovuk.bsky.social & @ivatolic.bsky.social @institutrb.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025... with
John Ankers
📷 @krunovuk.bsky.social & @ivatolic.bsky.social @institutrb.bsky.social in @natcomms.nature.com
➡️ bpod.org.uk/archive/2025... with
John Ankers
Researchers in Croatia, join us tomorrow at 9:30 in Zagreb or online to explore ERC grants! I’ll be sharing my experience from both sides of the table - as an ERC panel member and a grantee (Consolidator + Synergy). Bring your questions! @erc.europa.eu
link.europa.eu/dXQmbr
link.europa.eu/dXQmbr
December 9, 2025 at 6:56 PM
Researchers in Croatia, join us tomorrow at 9:30 in Zagreb or online to explore ERC grants! I’ll be sharing my experience from both sides of the table - as an ERC panel member and a grantee (Consolidator + Synergy). Bring your questions! @erc.europa.eu
link.europa.eu/dXQmbr
link.europa.eu/dXQmbr
Scientists, journalists, communicators, and policymakers in one room, rethinking how we talk about basic research in Europe! scicommforum.eu. See you at ZG SciComm 2026!
December 7, 2025 at 5:09 PM
Scientists, journalists, communicators, and policymakers in one room, rethinking how we talk about basic research in Europe! scicommforum.eu. See you at ZG SciComm 2026!
Do people outside academia understand the potential of EU basic research? I’ll be speaking in Session 2 “Let’s Pop The Balloon” at Zagreb Science Communication Forum 2025, on stepping outside the research bubble and reaching wider publics. scicommforum.eu
December 1, 2025 at 7:35 PM
Do people outside academia understand the potential of EU basic research? I’ll be speaking in Session 2 “Let’s Pop The Balloon” at Zagreb Science Communication Forum 2025, on stepping outside the research bubble and reaching wider publics. scicommforum.eu
When our institute’s legendary PR team tells our science story 🤩 @krunovuk.bsky.social @erc.europa.eu
www.nature.com/articles/s41... www.nature.com/articles/s41...
www.nature.com/articles/s41... www.nature.com/articles/s41...
November 25, 2025 at 3:20 PM
When our institute’s legendary PR team tells our science story 🤩 @krunovuk.bsky.social @erc.europa.eu
www.nature.com/articles/s41... www.nature.com/articles/s41...
www.nature.com/articles/s41... www.nature.com/articles/s41...
A golden Zagreb morning before work
October 31, 2025 at 8:47 PM
A golden Zagreb morning before work
And now… part two of our twin papers on how chromosomes find their place before division! Led by @krunovuk.bsky.social at @institutrb.bsky.social, out in @natcomms.nature.com!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
October 29, 2025 at 5:09 PM
And now… part two of our twin papers on how chromosomes find their place before division! Led by @krunovuk.bsky.social at @institutrb.bsky.social, out in @natcomms.nature.com!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Missed the thread on the first paper? Catch up:
bsky.app/profile/ivat...
Two back-to-back stories on mitosis led by my incredible postdoc @krunovuk.bsky.social at @institutrb.bsky.social, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in @natcomms.nature.com
doi.org/10.1038/s414...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
October 21, 2025 at 11:14 AM
Two back-to-back stories on mitosis led by my incredible postdoc @krunovuk.bsky.social at @institutrb.bsky.social, in which we challenge the gliding model of CENP-E-driven chromosome congression! Today in @natcomms.nature.com
doi.org/10.1038/s414...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Iva Tolić
#Mifobio2025
Focus on the module 5:
👉 Physical measurements, control and handling -Mechanobiology
We are delighted to welcome Professor @ivatolic.bsky.social
Ruđer Bošković Institute
Lecture : “Mechanobiology of the Mitotic Spindle”
👉 imabio-cnrs.fr
#GDRimabio #microscopy #biological_imaging
Focus on the module 5:
👉 Physical measurements, control and handling -Mechanobiology
We are delighted to welcome Professor @ivatolic.bsky.social
Ruđer Bošković Institute
Lecture : “Mechanobiology of the Mitotic Spindle”
👉 imabio-cnrs.fr
#GDRimabio #microscopy #biological_imaging
October 5, 2025 at 3:58 PM
#Mifobio2025
Focus on the module 5:
👉 Physical measurements, control and handling -Mechanobiology
We are delighted to welcome Professor @ivatolic.bsky.social
Ruđer Bošković Institute
Lecture : “Mechanobiology of the Mitotic Spindle”
👉 imabio-cnrs.fr
#GDRimabio #microscopy #biological_imaging
Focus on the module 5:
👉 Physical measurements, control and handling -Mechanobiology
We are delighted to welcome Professor @ivatolic.bsky.social
Ruđer Bošković Institute
Lecture : “Mechanobiology of the Mitotic Spindle”
👉 imabio-cnrs.fr
#GDRimabio #microscopy #biological_imaging
Reposted by Iva Tolić
🔬For 22 years, we have been organizing #Mifobio "Functional Microscopy for Biology" the @cnrs.fr thematic school.
🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.
👉 Program: imabio-cnrs.fr
#GDRImaBio #Mifobio2025
🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.
👉 Program: imabio-cnrs.fr
#GDRImaBio #Mifobio2025
October 3, 2025 at 10:45 PM
🔬For 22 years, we have been organizing #Mifobio "Functional Microscopy for Biology" the @cnrs.fr thematic school.
🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.
👉 Program: imabio-cnrs.fr
#GDRImaBio #Mifobio2025
🎓 Courses, Seminars, Round Tables, Workshops. The overall theme concerns #biological_imaging in its most interdisciplinary aspects.
👉 Program: imabio-cnrs.fr
#GDRImaBio #Mifobio2025
Reposted by Iva Tolić
Delighted to share our latest work showing how cells that evade #senescence after CDK4/6 inhibition are primed to become aneuploid because of their increased size (due to defects in cohesion and the mitotic checkpoint). Great work by fab PhD student Aanchal Pareri 👏🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cell enlargement causes mitotic errors and aneuploidy in cells that evade senescence after CDK4/6 inhibition
CDK4/6 inhibitors (CDK4/6i) arrest the cell cycle in G1 leading to cellular overgrowth and p53-dependent senescence. They are used to treat metastatic HR+/HER2- breast cancer, but resistance is common...
www.biorxiv.org
July 3, 2025 at 7:17 AM
Delighted to share our latest work showing how cells that evade #senescence after CDK4/6 inhibition are primed to become aneuploid because of their increased size (due to defects in cohesion and the mitotic checkpoint). Great work by fab PhD student Aanchal Pareri 👏🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Amazing energy at our second Swiss-Croatian Bilateral Project meeting with @labmeraldi.bsky.social and Pavin Group in Srebreno near Dubrovnik! The labs teamed up instantly, with lots of brainstorming and cool ideas for new joint projects! #HRZZ @snsf-ch.bsky.social
🇭🇷🇨🇭
🇭🇷🇨🇭
April 26, 2025 at 9:22 AM
Amazing energy at our second Swiss-Croatian Bilateral Project meeting with @labmeraldi.bsky.social and Pavin Group in Srebreno near Dubrovnik! The labs teamed up instantly, with lots of brainstorming and cool ideas for new joint projects! #HRZZ @snsf-ch.bsky.social
🇭🇷🇨🇭
🇭🇷🇨🇭
Great memories from the joint meeting with the Meraldi Lab and Pavin Group last year in Split! Can't wait for this year's meeting, which starts tomorrow! Excited for more cool science through our Swiss-Croatian Bilateral Project #HRZZ @snsf-ch.bsky.social 🇭🇷🇨🇭
April 8, 2025 at 6:29 AM
Great memories from the joint meeting with the Meraldi Lab and Pavin Group last year in Split! Can't wait for this year's meeting, which starts tomorrow! Excited for more cool science through our Swiss-Croatian Bilateral Project #HRZZ @snsf-ch.bsky.social 🇭🇷🇨🇭
Perfect for PhD students and postdocs! www.atoutcom.com/shaping-life...
March 21, 2025 at 12:54 PM
Perfect for PhD students and postdocs! www.atoutcom.com/shaping-life...
Happy first day of spring from our Institute @institutrb.bsky.social!
March 20, 2025 at 8:52 PM
Happy first day of spring from our Institute @institutrb.bsky.social!
Join us for this small, intensive workshop in the remote Alpine town of Arolla, where we will explore the dynamics of living systems across scales, from the cytoskeleton to embryos. Let’s dive into how cellular and tissue-scale dynamics shape life itself! meetings.ls2.ch/arolla2025
March 16, 2025 at 6:38 PM
Join us for this small, intensive workshop in the remote Alpine town of Arolla, where we will explore the dynamics of living systems across scales, from the cytoskeleton to embryos. Let’s dive into how cellular and tissue-scale dynamics shape life itself! meetings.ls2.ch/arolla2025
Reposted by Iva Tolić
Introducing blebbisomes! Cover art by @ento-sanchez.bsky.social! #CellBiology
Article: www.nature.com/articles/s41...
Article: www.nature.com/articles/s41...
March 15, 2025 at 1:48 PM
Introducing blebbisomes! Cover art by @ento-sanchez.bsky.social! #CellBiology
Article: www.nature.com/articles/s41...
Article: www.nature.com/articles/s41...
🚀Ever wondered if there's a universal rule of spindle scaling across eukaryotes? Turns out, there is! Our study reveals an evolutionarily conserved principle driven by a surprising factor: chromosome crowding. 🧵👇
shorturl.at/MmPNr
shorturl.at/MmPNr
March 10, 2025 at 4:25 PM
🚀Ever wondered if there's a universal rule of spindle scaling across eukaryotes? Turns out, there is! Our study reveals an evolutionarily conserved principle driven by a surprising factor: chromosome crowding. 🧵👇
shorturl.at/MmPNr
shorturl.at/MmPNr
Happy Women’s Day to all the amazing women out there! Special congrats to two incredible young scientists from my lab, Valentina Štimac & Isabella Koprivec, who earned their PhDs last year! 💡 And a spotlight on Valentina for winning the L'Oréal-UNESCO For Women in Science award! 🔥 #WomeninSTEM
March 8, 2025 at 6:31 PM
Happy Women’s Day to all the amazing women out there! Special congrats to two incredible young scientists from my lab, Valentina Štimac & Isabella Koprivec, who earned their PhDs last year! 💡 And a spotlight on Valentina for winning the L'Oréal-UNESCO For Women in Science award! 🔥 #WomeninSTEM