Manuel Thery
@manuelthery.bsky.social
cytoskeleton self-organization / shape, patterns and symmetry / minimal and artificial cells / biophysics teacher @ ESPCI ParisTech
www.cytomorpholab.com
www.cytomorpholab.com
Pinned
Manuel Thery
@manuelthery.bsky.social
· Nov 27
Mix two motors of opposite polarity with microtubules and they will partition space !
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
Microtubules will get organized in polar and active barriers, sorting the two motors in separated domains, leading to the emergence of a new type of patterns.
#morphogenesis
doi.org/10.1073/pnas...
(1/n)
nine fold symmetry
those-who-know know what i mean
those-who-know know what i mean
November 1, 2025 at 12:53 PM
nine fold symmetry
those-who-know know what i mean
those-who-know know what i mean
Reposted by Manuel Thery
Get out your calendars! The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
October 30, 2025 at 2:18 PM
Get out your calendars! The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
Reposted by Manuel Thery
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
October 26, 2025 at 2:01 AM
Domesticated animals have pulled our heavy carts and turned our large mills for centuries. But what about the opposite end of the spectrum—what if the wheel you want to turn is so small you can’t see it?
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Turns out we can harness the power of bacteria to power the world’s smallest machines.
1/7 ⚛️🧪
Tomorrow at @ISTAresearch.bsky.social in Vienna at 4:30 PM I will show and discuss how shapes can emerge (and disappear) from mixture of microtubules and molecular motors.
#morphogenesis
#morphogenesis
October 15, 2025 at 10:24 AM
Tomorrow at @ISTAresearch.bsky.social in Vienna at 4:30 PM I will show and discuss how shapes can emerge (and disappear) from mixture of microtubules and molecular motors.
#morphogenesis
#morphogenesis
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
October 14, 2025 at 1:50 PM
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
Reposted by Manuel Thery
Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI
bit.ly/Dynamic-Cell-VI
October 10, 2025 at 2:24 PM
Register for the Dynamic Cell VI conference, Reading, UK, April 2026! This conference focusses on all aspects of cell dynamics, co-organised by @bscb-official.bsky.social and @biochemsoc.bsky.social with @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology.
bit.ly/Dynamic-Cell-VI
bit.ly/Dynamic-Cell-VI
I see intraflagellar transport and dynamic steady states in living systems in this work by www.perry-cooper.com/about
Should we think of the bias in intracellular transports by "rewards"?
Should we think of the bias in intracellular transports by "rewards"?
October 10, 2025 at 2:02 PM
I see intraflagellar transport and dynamic steady states in living systems in this work by www.perry-cooper.com/about
Should we think of the bias in intracellular transports by "rewards"?
Should we think of the bias in intracellular transports by "rewards"?
Each cube can emit a light and sound to tell its neighbours it has heard something.
Check www.scenocosme.com/reactive_mat... for more details on this reactive matter.
Check www.scenocosme.com/reactive_mat... for more details on this reactive matter.
October 10, 2025 at 1:34 PM
Each cube can emit a light and sound to tell its neighbours it has heard something.
Check www.scenocosme.com/reactive_mat... for more details on this reactive matter.
Check www.scenocosme.com/reactive_mat... for more details on this reactive matter.
Reposted by Manuel Thery
Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Structure and Function of the Cytoskeleton
The cytoskeleton, a dynamic and intricate network of protein filaments, is found within the cytoplasm of all cells, from bacteria and archaea to complex eukaryotes. This essential cellular component …
meetings.embo.org
October 7, 2025 at 3:35 PM
Learn all things #cytoskeleton #research in an interdisciplinary environment at EMBO Workshop "Structure and Function of the Cytoskeleton" in Paris, FR, 7–10 April 2026.
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Deadline: 20 December 2025
https://meetings.embo.org/event/26-cytoskeleton
#EMBOCytoskeletalFunction #EMBOevents #conference 🧪
Reposted by Manuel Thery
MAP4-MAP7D1 partitioning on tyrosinated-detyrosinated microtubules coordinates lysosome positioning in nutrient signalling https://www.biorxiv.org/content/10.1101/2025.10.07.680844v1
October 8, 2025 at 2:30 AM
MAP4-MAP7D1 partitioning on tyrosinated-detyrosinated microtubules coordinates lysosome positioning in nutrient signalling https://www.biorxiv.org/content/10.1101/2025.10.07.680844v1
What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
October 7, 2025 at 3:08 PM
What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social
rupress.org/jcb/article-...
Reposted by Manuel Thery
Yusuke Maeda, from the department of Chemical Engineering of Kyoto University for a seminar on
Tuesday the 21st of October at 12:00
in the main amphitheatre of the IPGG (6 rue Jean Calvin).
Title and abstract:
From Flow to Shape: Biophysical Principles of Confined Actomyosin
Tuesday the 21st of October at 12:00
in the main amphitheatre of the IPGG (6 rue Jean Calvin).
Title and abstract:
From Flow to Shape: Biophysical Principles of Confined Actomyosin
October 6, 2025 at 6:10 PM
Yusuke Maeda, from the department of Chemical Engineering of Kyoto University for a seminar on
Tuesday the 21st of October at 12:00
in the main amphitheatre of the IPGG (6 rue Jean Calvin).
Title and abstract:
From Flow to Shape: Biophysical Principles of Confined Actomyosin
Tuesday the 21st of October at 12:00
in the main amphitheatre of the IPGG (6 rue Jean Calvin).
Title and abstract:
From Flow to Shape: Biophysical Principles of Confined Actomyosin
THE Erwin Frey, talking about self-organization in biological systems. Title of the seminar serie suggests it might be intended for physicists.
📌 Join us for the next klogW seminar on October 21st at 12PM EST (register below) by Erwin Frey @physicsoflifelmu.bsky.social on "Emergence and Self-organization in Biological Systems".
Registration link:
apsphysics.zoom.us/meeting/regi...
Registration link:
apsphysics.zoom.us/meeting/regi...
September 30, 2025 at 7:34 PM
THE Erwin Frey, talking about self-organization in biological systems. Title of the seminar serie suggests it might be intended for physicists.
intracellular mechanics ! in Barcelona in February (when its freezing anywherelse) !
Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio
meetings.embo.org/event/26-org...
meetings.embo.org/event/26-org...
Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
meetings.embo.org
September 30, 2025 at 7:31 PM
intracellular mechanics ! in Barcelona in February (when its freezing anywherelse) !
associate prof position in biophysics !
Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
www.biozentrum.unibas.ch/open-positio...
#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging
September 30, 2025 at 7:29 PM
associate prof position in biophysics !
Reposted by Manuel Thery
Beautiful drawing of ciliogenesis in airway cells from Sorokin, 1968: journals.biologists.com/jcs/article/.... Just shown on stage by @mahjoublab.bsky.social at #GEF25
September 30, 2025 at 7:41 AM
Beautiful drawing of ciliogenesis in airway cells from Sorokin, 1968: journals.biologists.com/jcs/article/.... Just shown on stage by @mahjoublab.bsky.social at #GEF25
The program is outstanding. Don't miss this opportunity to celebrate a giant.
We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.
mikeinmemoriam.sciencesconf.org
mikeinmemoriam.sciencesconf.org
September 29, 2025 at 5:32 PM
The program is outstanding. Don't miss this opportunity to celebrate a giant.
After so many years we keep
on drawing circles, lines, asters and arrows.
on drawing circles, lines, asters and arrows.
September 29, 2025 at 10:14 AM
After so many years we keep
on drawing circles, lines, asters and arrows.
on drawing circles, lines, asters and arrows.
Reposted by Manuel Thery
Paris Biological Physics Community Day (07/11/2025): Save the date!
Friday, November the 7th
Starting at 9h15
Laboratoire de Physique de l’École Normale Supérieure - Salle Jaurès - 29 rue d’Ulm 75005 Paris
www.phys.ens.psl.eu/parisyoung/
Friday, November the 7th
Starting at 9h15
Laboratoire de Physique de l’École Normale Supérieure - Salle Jaurès - 29 rue d’Ulm 75005 Paris
www.phys.ens.psl.eu/parisyoung/
Paris Biological Physics Community Day 2025
www.phys.ens.psl.eu
September 24, 2025 at 2:56 PM
Paris Biological Physics Community Day (07/11/2025): Save the date!
Friday, November the 7th
Starting at 9h15
Laboratoire de Physique de l’École Normale Supérieure - Salle Jaurès - 29 rue d’Ulm 75005 Paris
www.phys.ens.psl.eu/parisyoung/
Friday, November the 7th
Starting at 9h15
Laboratoire de Physique de l’École Normale Supérieure - Salle Jaurès - 29 rue d’Ulm 75005 Paris
www.phys.ens.psl.eu/parisyoung/
Reposted by Manuel Thery
Tissues transition between solid & fluid states in development & disease; cytoplasm turns crowded or inert to literally 'solidify'. Any connections? Turns out nothing's known. @sameerthukral.bsky.social & @bipashadey29.bsky.social pulled this review off brilliantly with a conceptual synthesis.
September 15, 2025 at 2:12 AM
Tissues transition between solid & fluid states in development & disease; cytoplasm turns crowded or inert to literally 'solidify'. Any connections? Turns out nothing's known. @sameerthukral.bsky.social & @bipashadey29.bsky.social pulled this review off brilliantly with a conceptual synthesis.
Reposted by Manuel Thery
Despite their high rigidity, microtubules (MTs) dynamically bend and buckle in cells. MT-self repair is inherent to their metastable nature, but it remains unclear whether just inherent repair mechanisms are sufficient to maintain MT integrity🧵 (1/9)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
September 14, 2025 at 9:53 AM
Despite their high rigidity, microtubules (MTs) dynamically bend and buckle in cells. MT-self repair is inherent to their metastable nature, but it remains unclear whether just inherent repair mechanisms are sufficient to maintain MT integrity🧵 (1/9)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Manuel Thery
Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳
We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.
Congratulations @subhambiswas.bsky.social!
www.nature.com/articles/s41...
We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.
Congratulations @subhambiswas.bsky.social!
www.nature.com/articles/s41...
September 11, 2025 at 6:03 PM
Happy to share that our paper on Tau- Microtubule interaction is now published in Nature Physics!🥳
We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.
Congratulations @subhambiswas.bsky.social!
www.nature.com/articles/s41...
We show that Tau isn’t just a microtubule stabiliser - it promotes removal of defects in the microtubule lattice.
Congratulations @subhambiswas.bsky.social!
www.nature.com/articles/s41...
Reposted by Manuel Thery
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
September 9, 2025 at 12:10 PM
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
Fabulous work showing how Tau catalyses microtubule repair
Excited to share that my paper on Tau–Microtubule interactions is now published in Nature Physics!🎉
Our work shows that tau goes beyond stabilizing microtubules—it also promotes the removal of defects in the microtubule lattice.
www.nature.com/articles/s41...
Our work shows that tau goes beyond stabilizing microtubules—it also promotes the removal of defects in the microtubule lattice.
www.nature.com/articles/s41...
Tau accelerates tubulin exchange in the microtubule lattice - Nature Physics
Beyond its known role in stabilizing microtubules, it is now shown that tau protein actively promotes lattice defect repair by enhancing tubulin turnover at topological defects.
www.nature.com
September 9, 2025 at 12:38 PM
Fabulous work showing how Tau catalyses microtubule repair
Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Paris Cytoskeleton Day 2025 - Sciencesconf.org
pcd2025.sciencesconf.org
September 9, 2025 at 12:32 PM
Which city is the best for Cytoskeleton research?
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !
Dresden? Barcelona? Cambridge ? Noooo ... you all know its Paris, right? 😎
Registering to the annual meeting on Friday 14th of November is now open:
pcd2025.sciencesconf.org
Keynote speeches by @carter-lab.bsky.social and Verena Ruprecht !