Pablo J. Sáez
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pjsaez.bsky.social
Pablo J. Sáez
@pjsaez.bsky.social
1.6K followers 450 following 200 posts
Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat.
I love to study how cells walk & talk.
PI of the @cellcommlab.bsky.social
#CellMigration #CellComm #calciumsignaling #organelles 🧪🔬
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pjsaez.bsky.social
Pablo J. Sáez @pjsaez.bsky.social · Jan 18
How cells decide where to go? #CellMigration

Last year we published our 1st paper @cellcommlab.bsky.social, showing how actin-based membrane oscillations define a new direction ( #cancer & non-cancer #cells )

Full www.nature.com/articles/s41...
@naturephysics.bsky.social @focalplane.bsky.social 🧪🔬
pjsaez.bsky.social
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).

Also the membrane dynamics are lovely.

It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
November 7, 2025 at 9:25 PM
Reposted by Pablo J. Sáez
bscb-official.bsky.social
Registration is OPEN for our Spring meeting: Dynamic Cell VI

🗓️ 21st-26th April 2026

📍Reading, UK

Co-organised with @biochemsoc.bsky.social @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology

Register here:

www.eventsforce.net/biochemsoc/f...
October 31, 2025 at 10:06 AM
Reposted by Pablo J. Sáez
seemagrewal.bsky.social
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella

journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
November 3, 2025 at 5:32 PM
Reposted by Pablo J. Sáez
manuelthery.bsky.social
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
October 14, 2025 at 1:50 PM
Reposted by Pablo J. Sáez
actonlab.bsky.social
We hiring! Please share this post with your talented ECRs

We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome

Based at @lmcb-ucl.bsky.social at University College London

Apply here:
www.jobs.ac.uk/job/DPD418/r...
October 21, 2025 at 3:57 PM
Reposted by Pablo J. Sáez
martinowk.bsky.social
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience

recruiting.paylocity.com/recruiting/j...
Lieber Institute For Brain Development - Staff Scientist I, Translational Neuroscience
A little about us:The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with develop...
recruiting.paylocity.com
October 29, 2025 at 4:03 PM
Reposted by Pablo J. Sáez
sfb1348.bsky.social
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
October 27, 2025 at 7:00 AM
pjsaez.bsky.social
Kudos to @eliasbarrigalab.bsky.social for the Innovation DGZ Prize for his work on #CellMigration

A great Chilean 🇨🇱 in #STEM 💪🏽🔥

@dgz.bsky.social #DGZ50
October 27, 2025 at 5:26 PM
pjsaez.bsky.social
When your email box is so bad that every time day you are in the "my dog eat the homework" situation...
But this email is actually a dog, that actually eats the homeworks...wtf
a crowd of people with their hands on their heads
ALT: a crowd of people with their hands on their heads
media.tenor.com
October 20, 2025 at 11:08 AM
Reposted by Pablo J. Sáez
amsikking.bsky.social
The future of High-Content Imaging has arrived.

-> Ultra-fast 3D imaging of multi-well plates at high resolution using an air objective!

See previous posts and the new miOPM preprint for details: doi.org/10.1101/2025...
October 13, 2025 at 12:44 AM
Reposted by Pablo J. Sáez
avezovlab.bsky.social
New preprint from our lab! ER geometry sets the tempo of neuronal bursting via Ca²⁺ store-refill—revealing selective neuronal vulnerability to ER-structure problems. Thread to follow.🧠⚡️

www.biorxiv.org/content/10.1...

#Neurodegeneration #NeuroCellBiology #Calcium #bioRxiv
October 9, 2025 at 1:08 PM
Reposted by Pablo J. Sáez
natclarke.bsky.social
🚨 My lab is hiring at all levels!

Interested in animal origins & evolutionary cell biology?

I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.

🔗: clarkelab.com/join/

Please repost!
October 8, 2025 at 5:49 PM
pjsaez.bsky.social
Do you like the @npr.org tiny desk? Try this one👇🏽

"31 minutos" was one the most viewed shows "for kids" in Latin America.
It's the Chilean 🇨🇱 version of Sesame Street with acid humour, political critic & great music played by members of actual bands!
#31minutos en #ElTiny

youtu.be/UEqTIwRrWvA?...
31 Minutos: Tiny Desk Concert
YouTube video by NPR Music
youtu.be
October 7, 2025 at 6:44 PM
Reposted by Pablo J. Sáez
plosbiology.org
During #development, distal visceral #endoderm (DVE) cells migrate to shape A-P axis specification. @m-stower.bsky.social @srinivas-lab.bsky.social &co reveal the role of Ca2+ dynamics in this, showing that inhibition of #calcium transients causes DVE arrest @plosbiology.org 🧪 plos.io/4nHWxF4
Epiblast Ca2+ waves propagate from the apical to basal domain. The images show selected time points from movies of E5.5 GCaMP6f embryos imaged using a ZEISS lattice light-sheet 7 microscope. Top row: An example of an epiblast wave involving a large proportion of the tissue captured by imaging a volume of the embryo at 20-s intervals. A total of 9/16 embryos showed at least one epiblast Ca2+ wave. Bottom row: Faster imaging at 5-s interval revealed that the Ca2+ wave in the epiblast can be preceded by a transient in a neighboring VE cell—this was observed in 5/19 events from 9 embryos (white arrowheads).
October 7, 2025 at 8:18 AM
Reposted by Pablo J. Sáez
jytinevez.bsky.social
Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...
Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA
Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...
forum.image.sc
October 7, 2025 at 12:39 PM
Reposted by Pablo J. Sáez
manuelthery.bsky.social
What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social

rupress.org/jcb/article-...
October 7, 2025 at 3:08 PM
Reposted by Pablo J. Sáez
katrinavelle.bsky.social
PhD or Master's position available for Fall 2026!

Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!
October 5, 2025 at 5:29 PM
Reposted by Pablo J. Sáez
napari.org
napari 0.6.5 is out! 🚀

Rapid-fire highlights are: colorbar overlay, custom startup script, and better and prettier documentation! Check out the full release notes here: napari.org/dev/release/...
Image depicting the napari viewer in grid mode with scale bars and color bars enabled
October 2, 2025 at 11:44 AM
Reposted by Pablo J. Sáez
felixmendu.bsky.social
Announcing a new @embo.org Workshop on "Intracellular mechanics and organelle mechanobiology" that we are organizing with Michael Krieg and Verena Ruprecht at @icfo.eu (Barcelona) on 16-20 February, 2026. Please, repost and spread the word! 🙏 #EMBOmechanobio

meetings.embo.org/event/26-org...
Intracellular mechanics and organelle mechanobiology
Mechanobiology is an interdisciplinary field that emerges at the cross-section of biology, physics and engineering. It aims to understand how living cells, tissues and animals sense and respond to me…
meetings.embo.org
July 4, 2025 at 3:50 PM
pjsaez.bsky.social
Happily checking grant application instructions until I found that a collaborator, who is a co-applicant is part of the evaluation committee...
why...why...
a close up of yoda with suffering written on the bottom
ALT: a close up of yoda with suffering written on the bottom
media.tenor.com
September 28, 2025 at 9:27 PM
Reposted by Pablo J. Sáez
france-bioimaging.bsky.social
We are thrilled to announce that our Image Contest is back! 🔬🏆

Submit your best images & try to win your registration fees for one 2026 #microscopy related event.
📆Before November 14th, 2025

Info & entries👉 france-bioimaging.org/fbi-special-...

We are all eager to see your work!
September 16, 2025 at 9:04 AM
Reposted by Pablo J. Sáez
radinbio.bsky.social
Do you know what happens when you touch a carnivorous sundew plant?
If the touch is strong and large enough, a cytosolic calcium wave will spread from the site of touch throughout the whole plant, but if you only touch one tentacle (see post below), the calcium wave will be local and less intense.
September 15, 2025 at 2:26 PM
Reposted by Pablo J. Sáez
worzfeld.bsky.social
Great to be invited to the 5th Inflammation & Imaging Symposium in Münster with exciting scientific talks and discussions! www.uni-muenster.de/Cells-in-Mot... @uni-muenster.de
September 9, 2025 at 3:23 PM
Reposted by Pablo J. Sáez
obenaufa.bsky.social
Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!
Full Professorship in Molecular Mechanisms of Disease
The Max Perutz Labs - one of Europe’s leading institutes for basic research in the life sciences - invite applications for a Full Professorship in Molecular Mechanisms of Disease. We are seeking outst...
www.maxperutzlabs.ac.at
September 4, 2025 at 10:25 AM
pjsaez.bsky.social
Today 20 years after I started working in a scientific lab while still in 🇨🇱, my lab, the @cellcommlab.bsky.social has its 5th labversary.

What a ride ! I'm thankful for the support of my family, friends, & so many great collabs & colleagues.

Fig legend 👇🏽 + pending longer thread #PIlife #Science
September 1, 2025 at 10:00 PM