Pablo J. Sáez
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pjsaez.bsky.social
Pablo J. Sáez
@pjsaez.bsky.social
Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat.
I love to study how cells walk & talk.
PI of the @cellcommlab.bsky.social
#CellMigration #CellComm #calciumsignaling #organelles 🧪🔬
Pinned
How cells decide where to go? #CellMigration

Last year we published our 1st paper @cellcommlab.bsky.social, showing how actin-based membrane oscillations define a new direction ( #cancer & non-cancer #cells )

Full www.nature.com/articles/s41...
@naturephysics.bsky.social @focalplane.bsky.social 🧪🔬
Reposted by Pablo J. Sáez
CRC cells pulling on Collagen I show increased calcium fluctuations, visualized with the calcium reporter K-GECO1
November 7, 2025 at 4:33 PM
Reposted by Pablo J. Sáez
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
Reposted by Pablo J. Sáez
Cell migration is a key cellular process that drives major developmental programs and diseases.

Different assays have been developed, but they are often used interchangeably.

In our new paper, we describe how to select the optimal assay.

More details here: www.nature.com/articles/s41...
December 27, 2025 at 12:46 PM
Reposted by Pablo J. Sáez
Attention scientists from all over the world🙃
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
December 15, 2025 at 2:52 PM
Reposted by Pablo J. Sáez
🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
Reposted by Pablo J. Sáez
Come work with us! We are looking for a postdoc in #philbio or #philphysics to work on an interdisciplinary project that adopts the lens of self-organization & active matter to explore the boundary between living & nonliving systems www.kuleuven.be/personeel/jo... #academicsky #philjobs #HPS #evosky
December 8, 2025 at 11:21 AM
Reposted by Pablo J. Sáez
Interested in cell adhesion, evolution of multicellularity, or developing tools for emerging marine models?

My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa

If you know anyone looking for a postdoc, please pass this along!
December 8, 2025 at 6:37 PM
Reposted by Pablo J. Sáez
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.
December 4, 2025 at 8:42 AM
Hot from the press !

Happy to see this out, and that @cellcommlab.bsky.social contributed with live-cell imaging

Autoimmunoglobulin-triggered extracellular vesicles (movie) contribute to kidney disease

Full www.cell.com/cell/fulltex...
@focalplane.bsky.social @cp-cell.bsky.social #microscopy 🧪🔬
December 4, 2025 at 3:41 PM
Reposted by Pablo J. Sáez
Volumetric near-infrared light-sheet imaging of a calcium indicator (WHaloCaMP) in a zebrafish larval brain. Credit to @helenfarrants.bsky.social, William "Bill" Lemon, & Philipp Keller at @hhmijanelia.bsky.social. #ZebrafishZunday 🧪
November 30, 2025 at 9:31 AM
Reposted by Pablo J. Sáez
📢Internships on cellular nematics!

🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.

📧Feel free to DM or email me with any questions.
December 2, 2025 at 3:15 PM
Reposted by Pablo J. Sáez
Apply for our Pathway to Independence (PI) programme, supporting postdocs in #devbio and #stemcell research during the transition to their first group leader position: www.biologists.com/grants/devel...

Application deadline: 2 February 2026.
December 2, 2025 at 2:53 PM
Hot from the #preprint

Leukocyte + #CellMigration + physics = cool

Microtubules enable torque-based steering during dendritic cell migration.

Actomyosin contractility is required for noise-modulation strategy used by neutrophils.

Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Torque-based immune cell chemotaxis in complex environments
Directed migration in chemical gradients is crucial to the immune response, yet how immune cells navigate complex tissues remains incompletely understood. Using in vitro migration assays and theoretic...
www.biorxiv.org
November 23, 2025 at 2:39 PM
Even if "provisionally" accepted, those are the best words/news I've heard for quite a while...

Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.

@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
November 21, 2025 at 2:55 PM
Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social

By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...

www.hfsp.org/hfsp-events/...
HFSP Webinar 2025: Research Grants | Human Frontier Science Program
www.hfsp.org
November 19, 2025 at 8:36 AM
I guess it never gets old...bc we love #CellMigration

ATP has many roles: energy currency, hydrotrope, and *danger signal*

Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!

www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
November 14, 2025 at 8:38 PM
Reposted by Pablo J. Sáez
ICYMI - In September, we co-hosted a mini-symposium with the Membrane Trafficking webinar series. You can view the recordings of the talks from @nickader.bsky.social, @maiblab.bsky.social and Mónica Quiñones-Frías, and the keynote lecture from Gillian Griffiths @griffithslab.bsky.social.
FocalPlane features... membrane trafficking recordings - FocalPlane
FocalPlane features... membrane trafficking recordings - News
focalplane.biologists.com
November 14, 2025 at 2:33 PM
Reposted by Pablo J. Sáez
To help you plan your conference travel for 2026, we’ve been busy updating our #CellBiology events calendar on FocalPlane.

If we are missing your event, feel free to add it to the calendar or reach out to our Community Manager @helenzsci.bsky.social.
focalplane.biologists.com/cell-biology...
November 12, 2025 at 2:05 PM
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).

Also the membrane dynamics are lovely.

It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
November 7, 2025 at 9:25 PM
Reposted by Pablo J. Sáez
Registration is OPEN for our Spring meeting: Dynamic Cell VI

🗓️ 21st-26th April 2026

📍Reading, UK

Co-organised with @biochemsoc.bsky.social @royalmicrosoc.bsky.social and the Chinese Society for Cell Biology

Register here:

www.eventsforce.net/biochemsoc/f...
October 31, 2025 at 10:06 AM
Reposted by Pablo J. Sáez
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella

journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
November 3, 2025 at 5:32 PM
Reposted by Pablo J. Sáez
We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...
October 14, 2025 at 1:50 PM
Reposted by Pablo J. Sáez
We hiring! Please share this post with your talented ECRs

We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome

Based at @lmcb-ucl.bsky.social at University College London

Apply here:
www.jobs.ac.uk/job/DPD418/r...
October 21, 2025 at 3:57 PM
Reposted by Pablo J. Sáez
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience

recruiting.paylocity.com/recruiting/j...
Lieber Institute For Brain Development - Staff Scientist I, Translational Neuroscience
A little about us:The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with develop...
recruiting.paylocity.com
October 29, 2025 at 4:03 PM
Reposted by Pablo J. Sáez
Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...
October 27, 2025 at 7:00 AM