Gerrich
@gerrich.bsky.social
Non-conventional microbes, metabolic engineering and microbial genetics. Bacteria go brrr
Finally, finished with my thesis, now off to new frontiers!
https://orcid.org/0009-0004-1949-532X
Finally, finished with my thesis, now off to new frontiers!
https://orcid.org/0009-0004-1949-532X
Pinned
Gerrich
@gerrich.bsky.social
· Jan 7
Construction and comparison of different vehicles for heterologous gene expression in Zymomonas mobilis
In this study, a series of shuttle vectors compatible with modular cloning were constructed based on the replication mechanisms of the native Z. mobilis plasmids pZMO1, pZMOB04, pZMOB05, pZMOB06, pZM...
doi.org
My last thesis paper post:
This one is for plasmid enthusiasts.
Comparing seven different replication system for application in the Zymomonas mobilis.
The pBBR1 replicon and six replicons from native Z. mobilis plasmids of different strains.
Published in @microbiotech.bsky.social 🧪
This one is for plasmid enthusiasts.
Comparing seven different replication system for application in the Zymomonas mobilis.
The pBBR1 replicon and six replicons from native Z. mobilis plasmids of different strains.
Published in @microbiotech.bsky.social 🧪
Reposted by Gerrich
Bluesky is definitely a place for science, research and citing papers. We hope it will continue to close the gap as rapidly as it has with legacy social media. Research, science and dank memes need many homes on the internet.
Bluesky provides one of the more inviting ones.
Happy New Year.
Bluesky provides one of the more inviting ones.
Happy New Year.
a man wearing a beanie says " yeah science "
Alt: Jeffie (ok Jessie) Pinkman from Breaking Bad wearing a beanie says " yeah science" and points.
Hey did anyone watch Pluribus? Sick show, we Stan Vince Gilligan. I bet his middle name is Jeff.
media.tenor.com
January 8, 2026 at 1:08 PM
Bluesky is definitely a place for science, research and citing papers. We hope it will continue to close the gap as rapidly as it has with legacy social media. Research, science and dank memes need many homes on the internet.
Bluesky provides one of the more inviting ones.
Happy New Year.
Bluesky provides one of the more inviting ones.
Happy New Year.
Reposted by Gerrich
Totally! 💯
Whenever there is a survey here in the UK, I keep suggesting that every grant holder should review 4 grant proposals per year for the body from which they receive funding. This should be a commitment at the stage of accepting the award.
If you have received,you give back to the community
Whenever there is a survey here in the UK, I keep suggesting that every grant holder should review 4 grant proposals per year for the body from which they receive funding. This should be a commitment at the stage of accepting the award.
If you have received,you give back to the community
If they do it because they can’t find reviewers, the solution is very simple: you review 3 grants for every grant you submit. If you don’t or do a bad job, you are banned from submitting for a year. If they really think AI can do a better job at judging grants than us, we should close shop.
January 9, 2026 at 8:36 AM
Totally! 💯
Whenever there is a survey here in the UK, I keep suggesting that every grant holder should review 4 grant proposals per year for the body from which they receive funding. This should be a commitment at the stage of accepting the award.
If you have received,you give back to the community
Whenever there is a survey here in the UK, I keep suggesting that every grant holder should review 4 grant proposals per year for the body from which they receive funding. This should be a commitment at the stage of accepting the award.
If you have received,you give back to the community
Reposted by Gerrich
After 4 years of joint effort of my Lab and Dr. Llorente Team we took for first time SCRaMbLE to a bacterial system! This allowed us to massively reordered the main chromosome of Vibrio natriegens!
biorxiv.org/content/10.6...
Here's a 🧵
biorxiv.org/content/10.6...
Here's a 🧵
Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change
The ability to generate genomic diversity expands opportunities for understanding and engineering biology. Here, we demonstrate on-demand generation of diversity in bacterial genome configurations and...
biorxiv.org
January 8, 2026 at 8:25 PM
After 4 years of joint effort of my Lab and Dr. Llorente Team we took for first time SCRaMbLE to a bacterial system! This allowed us to massively reordered the main chromosome of Vibrio natriegens!
biorxiv.org/content/10.6...
Here's a 🧵
biorxiv.org/content/10.6...
Here's a 🧵
Reposted by Gerrich
March 28, 2025 at 5:18 PM
Reposted by Gerrich
A few years ago, through luck and vibes, I managed to produce this blue colored bean variety.
This was an early step in trying to answer the question, [paraphrased] "Why isn't blue as common as red in beans, even though they're both anthocyanins and the plant has the genes for both?"
This was an early step in trying to answer the question, [paraphrased] "Why isn't blue as common as red in beans, even though they're both anthocyanins and the plant has the genes for both?"
December 29, 2025 at 7:14 AM
A few years ago, through luck and vibes, I managed to produce this blue colored bean variety.
This was an early step in trying to answer the question, [paraphrased] "Why isn't blue as common as red in beans, even though they're both anthocyanins and the plant has the genes for both?"
This was an early step in trying to answer the question, [paraphrased] "Why isn't blue as common as red in beans, even though they're both anthocyanins and the plant has the genes for both?"
Doing some tricky organic chemistry with "Feuerzangenbowle".
December 25, 2025 at 7:44 PM
Doing some tricky organic chemistry with "Feuerzangenbowle".
Reposted by Gerrich
These strange trees are called 'pewen' or 'piñonero' in their native Chile, but when they reached England as an ornamental, barrister Charles Austin commented:
"It would puzzle a monkey to climb that"
So now, in English, they're called "monkey-puzzles."
They get weirder up close...
"It would puzzle a monkey to climb that"
So now, in English, they're called "monkey-puzzles."
They get weirder up close...
December 23, 2025 at 10:39 PM
These strange trees are called 'pewen' or 'piñonero' in their native Chile, but when they reached England as an ornamental, barrister Charles Austin commented:
"It would puzzle a monkey to climb that"
So now, in English, they're called "monkey-puzzles."
They get weirder up close...
"It would puzzle a monkey to climb that"
So now, in English, they're called "monkey-puzzles."
They get weirder up close...
Reposted by Gerrich
Reposted by Gerrich
Today's timeline theme is "Awesome Shirts" apparently.
December 18, 2025 at 12:54 PM
Today's timeline theme is "Awesome Shirts" apparently.
Reposted by Gerrich
A long standing goal in synthetic biology is ‘PURE makes PURE’ - effectively the start of self-replicating biology in a tube from just adding biochemicals and DNA instructions. This looks like a promising breakthrough from the Maerkl lab. 👀
PURE makes PURE: reconstitution of the PURE cell-free system from self-synthesized non-ribosomal proteins https://www.biorxiv.org/content/10.64898/2025.12.17.694911v1
December 18, 2025 at 5:38 AM
A long standing goal in synthetic biology is ‘PURE makes PURE’ - effectively the start of self-replicating biology in a tube from just adding biochemicals and DNA instructions. This looks like a promising breakthrough from the Maerkl lab. 👀
Reposted by Gerrich
Slight improvement by team members 😅
December 17, 2025 at 2:57 PM
Slight improvement by team members 😅
Reposted by Gerrich
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 12:46 AM
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
December 16, 2025 at 8:51 PM
Reposted by Gerrich
Cetraria islandica, an edible #lichen, often called Iceland Moss…even though it isn’t a moss. Looks very Star Trek. Newfoundland, Canada. #fungi #fungifriends
December 16, 2025 at 6:14 PM
Cetraria islandica, an edible #lichen, often called Iceland Moss…even though it isn’t a moss. Looks very Star Trek. Newfoundland, Canada. #fungi #fungifriends
Reposted by Gerrich
🗞️ New preprint from the lab, led by our postdoc Ana Garoña (not on here) in collab with @andreagiometto.bsky.social: “Experimental evolution of cellular miniaturization reveals a mechanism for cell size evolution”, aka: “honey, we shrank the yeasts!” 🎥
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
December 9, 2025 at 5:08 PM
🗞️ New preprint from the lab, led by our postdoc Ana Garoña (not on here) in collab with @andreagiometto.bsky.social: “Experimental evolution of cellular miniaturization reveals a mechanism for cell size evolution”, aka: “honey, we shrank the yeasts!” 🎥
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Gerrich
The 2025 Agar Art Contest winners have been selected! This year’s theme, “Microbes Make the World Go Round,” inspired 557 global entries—from food fermentation to antibiotic production. See the masterpieces and finalists! asm.org/press-releas... #agarart
December 15, 2025 at 4:59 PM
The 2025 Agar Art Contest winners have been selected! This year’s theme, “Microbes Make the World Go Round,” inspired 557 global entries—from food fermentation to antibiotic production. See the masterpieces and finalists! asm.org/press-releas... #agarart
Reposted by Gerrich
Genetic engineering, painting, sculpting, floristry, and fantasy are united in @nickdesnoyer.bsky.social 's flower design art project. New essay out now on a blossoming frontier of transgenic art!
Mutating The Medium
A blooming future for biodesign
allmovingparts.substack.com
December 15, 2025 at 5:43 PM
Genetic engineering, painting, sculpting, floristry, and fantasy are united in @nickdesnoyer.bsky.social 's flower design art project. New essay out now on a blossoming frontier of transgenic art!
Reposted by Gerrich
Pleased to share this thoughtful essay by Jess on my flower design project🌹🧬
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
December 15, 2025 at 5:51 PM
Pleased to share this thoughtful essay by Jess on my flower design project🌹🧬
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
As a small thank-you for spreading the work, I'm randomly giving away 5 of these new morphogenesis hoodies to whoever reposts this!
Love it when a Golde Gate cloning result looks like this. 🦠
December 15, 2025 at 1:40 PM
Love it when a Golde Gate cloning result looks like this. 🦠
I am obsessing waaay too much about getting cited for my research this year.
December 15, 2025 at 10:48 AM
I am obsessing waaay too much about getting cited for my research this year.
Reposted by Gerrich
Compared to restriction-modification systems, streamlined plasmids prevent hosts from acquiring AMR plasmids more effectively! RM is effective in the short-term, however plasmids escape restriction fast (very likely via methylation) whereas streamlined plasmids remain efficient over several days.
December 12, 2025 at 12:09 PM
Compared to restriction-modification systems, streamlined plasmids prevent hosts from acquiring AMR plasmids more effectively! RM is effective in the short-term, however plasmids escape restriction fast (very likely via methylation) whereas streamlined plasmids remain efficient over several days.
Reposted by Gerrich
PhD contract available in the @icmabcsic.bsky.social in my group to work on the synthesis and characterization of New Photosensitisers for Panchromatic Photoisomerization. Retweets appreciated. Candidates please contact me directly.
December 12, 2025 at 10:42 AM
PhD contract available in the @icmabcsic.bsky.social in my group to work on the synthesis and characterization of New Photosensitisers for Panchromatic Photoisomerization. Retweets appreciated. Candidates please contact me directly.
Reposted by Gerrich
reading about genAI slop brokers makes me want to draw more weird manual art. extremely realistic brachiosaurus reconstruction for you
December 12, 2025 at 5:06 AM
reading about genAI slop brokers makes me want to draw more weird manual art. extremely realistic brachiosaurus reconstruction for you
Reposted by Gerrich
Check out this work by the amazing @leahmcphillips.bsky.social from during her PhD!!
Stable inheritance of the Streptomyces linear plasmid SCP1 by dual ParABS partition systems https://www.biorxiv.org/content/10.64898/2025.12.10.693275v1
December 11, 2025 at 8:10 AM
Check out this work by the amazing @leahmcphillips.bsky.social from during her PhD!!
Reposted by Gerrich
As 2025 wraps up, we’re looking back at some of the most intriguing microbes that made their scientific debut this year. This blog highlights standout bacterial species that caught our eye. Read the full #FEMSmicroBlog: buff.ly/2wz7k16
#NewMicrobes
#NewMicrobes
December 10, 2025 at 11:01 AM
As 2025 wraps up, we’re looking back at some of the most intriguing microbes that made their scientific debut this year. This blog highlights standout bacterial species that caught our eye. Read the full #FEMSmicroBlog: buff.ly/2wz7k16
#NewMicrobes
#NewMicrobes