Chen Davidovich
@davidovichlab.bsky.social
Gene repression, RNA and all chromatin things.
@MonashUni, Melbourne, Australia.
https://www.davidovich-lab.com/
@MonashUni, Melbourne, Australia.
https://www.davidovich-lab.com/
Pinned
1/ H3K27me3 mimicry has repeatedly emerged through evolution, but what's the physiological relevance?
We show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2 in vivo and restrict the spread of Polycomb domains.
🧵
www.biorxiv.org/content/10.1...
We show that JARID2 and PALI1 mimic H3K27me3 to antagonise PRC2 in vivo and restrict the spread of Polycomb domains.
🧵
www.biorxiv.org/content/10.1...
Reposted by Chen Davidovich
Two alternative isoforms of PRC2 accessory subunit AEBP2 modulate developmental Polycomb functions in opposite ways - with broadly-expressed AEBP2L acting as an intrinsic inhibitor in somatic cells
@adrianbracken.bsky.social @davidovichlab.bsky.social and colleagues
www.embopress.org/doi/full/10....
@adrianbracken.bsky.social @davidovichlab.bsky.social and colleagues
www.embopress.org/doi/full/10....
November 4, 2025 at 12:51 PM
Two alternative isoforms of PRC2 accessory subunit AEBP2 modulate developmental Polycomb functions in opposite ways - with broadly-expressed AEBP2L acting as an intrinsic inhibitor in somatic cells
@adrianbracken.bsky.social @davidovichlab.bsky.social and colleagues
www.embopress.org/doi/full/10....
@adrianbracken.bsky.social @davidovichlab.bsky.social and colleagues
www.embopress.org/doi/full/10....
Reposted by Chen Davidovich
@ckadoch.bsky.social and I are excited to welcome you to Geneva for the 2026 Keystone Symposium on Epigenetics and Gene Regulation in Health and Disease — short talk and poster slots are still open. Don’t miss the deadlines.
Video: youtu.be/sLfyuQuH8F0
Video: youtu.be/sLfyuQuH8F0
KSQA: Dr Karim-Jean Armache / Dr. Cigall Kadoch (Epigenetics and Gene Regulation)
YouTube video by KeystoneSymposia
youtu.be
November 3, 2025 at 2:43 PM
@ckadoch.bsky.social and I are excited to welcome you to Geneva for the 2026 Keystone Symposium on Epigenetics and Gene Regulation in Health and Disease — short talk and poster slots are still open. Don’t miss the deadlines.
Video: youtu.be/sLfyuQuH8F0
Video: youtu.be/sLfyuQuH8F0
1/ It's long been assumed that AEBP2 recruit PRC2 to chromatin. Now, we show that AEBP2 usually does the exact opposite:
The only isoform of AEBP2 that is expressed in most cell types and tissues inhibits the chromatin-binding activity of PRC2. www.embopress.org/doi/full/10....
The only isoform of AEBP2 that is expressed in most cell types and tissues inhibits the chromatin-binding activity of PRC2. www.embopress.org/doi/full/10....
Auto-inhibition of PRC2 by the broadly expressed long isoform of AEBP2 | The EMBO Journal
imageimageAEBP2 is an accessory subunit of the PRC2 complex previously implicated both in promoting
and antagonizing Polycomb repressive activity. This study reveals that its alternative
isoforms, AEB...
www.embopress.org
October 31, 2025 at 10:42 PM
1/ It's long been assumed that AEBP2 recruit PRC2 to chromatin. Now, we show that AEBP2 usually does the exact opposite:
The only isoform of AEBP2 that is expressed in most cell types and tissues inhibits the chromatin-binding activity of PRC2. www.embopress.org/doi/full/10....
The only isoform of AEBP2 that is expressed in most cell types and tissues inhibits the chromatin-binding activity of PRC2. www.embopress.org/doi/full/10....
Reposted by Chen Davidovich
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
October 31, 2025 at 10:53 AM
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
Reposted by Chen Davidovich
📣 Abstract Deadline Extended!
Due to popular demand, we’ve extended the submission deadline — giving you a few extra days to finalise your abstract.
Don’t miss out on being part of Lorne’s legacy!
👉 Submit today: www.lorneproteins.org
#LorneProteins #DeadlineExtended #ProteinScience
Due to popular demand, we’ve extended the submission deadline — giving you a few extra days to finalise your abstract.
Don’t miss out on being part of Lorne’s legacy!
👉 Submit today: www.lorneproteins.org
#LorneProteins #DeadlineExtended #ProteinScience
October 26, 2025 at 10:59 PM
📣 Abstract Deadline Extended!
Due to popular demand, we’ve extended the submission deadline — giving you a few extra days to finalise your abstract.
Don’t miss out on being part of Lorne’s legacy!
👉 Submit today: www.lorneproteins.org
#LorneProteins #DeadlineExtended #ProteinScience
Due to popular demand, we’ve extended the submission deadline — giving you a few extra days to finalise your abstract.
Don’t miss out on being part of Lorne’s legacy!
👉 Submit today: www.lorneproteins.org
#LorneProteins #DeadlineExtended #ProteinScience
Reposted by Chen Davidovich
ARC says Discovery Projects outcomes will be tomorrow (Tuesday). Linkage Projects (2025, round 1) on Wed. Over past ~year, it's often been at about 11am (Canberra).
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
October 26, 2025 at 11:17 PM
ARC says Discovery Projects outcomes will be tomorrow (Tuesday). Linkage Projects (2025, round 1) on Wed. Over past ~year, it's often been at about 11am (Canberra).
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
My bot will pick up the change to RMS & post immediately.
ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs
Reposted by Chen Davidovich
🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇
#CancerResearch #Epigenetics #Chromatin #Lymphoma
#CancerResearch #Epigenetics #Chromatin #Lymphoma
AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma
The catalytic subunit of Polycomb Repressive Complex 2 (PRC2), EZH2, is recurrently mutated in 25% of diffuse large B-cell lymphomas (DLBCL), causing increased H3K27me3 and decreased H3K27me2 levels. ...
www.biorxiv.org
October 17, 2025 at 7:11 AM
🧵1/Exciting news in cancer epigenetics! Our latest research, "AEBP2-Directed H3K27me2 Defines a Specific Vulnerability in EZH2-mutant Lymphoma", is now available on www.biorxiv.org/content/10.1.... Here's a thread summarizing our findings!👇
#CancerResearch #Epigenetics #Chromatin #Lymphoma
#CancerResearch #Epigenetics #Chromatin #Lymphoma
Reposted by Chen Davidovich
EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026.
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
September 28, 2025 at 12:00 AM
EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026.
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026
Reposted by Chen Davidovich
Super glad to contribute to this study on chromatin evolution in brown algae! Special thanks to Jeromine Vigneau, @borglab.bsky.social and Susana Coelho for making this happen.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Rewiring of chromatin regulation underlies the evolution of brown algal multicellularity
Chromatin structure plays a central role in regulating transcription, genome stability, and epigenetic inheritance in eukaryotes. Much of our understanding of chromatin architecture and histone post-t...
www.biorxiv.org
September 19, 2025 at 7:02 PM
Super glad to contribute to this study on chromatin evolution in brown algae! Special thanks to Jeromine Vigneau, @borglab.bsky.social and Susana Coelho for making this happen.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Chen Davidovich
Genes and Gin: A Synthetic Biology Social 🎉
Join us for a fun night of Genes and Gin - learn to play the synthetic card game "Remediate!", created by a group of researchers within our Centre.
Make sure you register for catering:
www.eventbrite.com.au/e/genes-and-...
See you on the rooftop!
Join us for a fun night of Genes and Gin - learn to play the synthetic card game "Remediate!", created by a group of researchers within our Centre.
Make sure you register for catering:
www.eventbrite.com.au/e/genes-and-...
See you on the rooftop!
September 18, 2025 at 12:58 AM
Genes and Gin: A Synthetic Biology Social 🎉
Join us for a fun night of Genes and Gin - learn to play the synthetic card game "Remediate!", created by a group of researchers within our Centre.
Make sure you register for catering:
www.eventbrite.com.au/e/genes-and-...
See you on the rooftop!
Join us for a fun night of Genes and Gin - learn to play the synthetic card game "Remediate!", created by a group of researchers within our Centre.
Make sure you register for catering:
www.eventbrite.com.au/e/genes-and-...
See you on the rooftop!
Reposted by Chen Davidovich
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
September 17, 2025 at 3:03 PM
Many of the most complex and useful functions in biology emerge at the scale of whole genomes.
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
Reposted by Chen Davidovich
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
Epigenetic relay: Polycomb-directed DNA methylation in mammalian development
In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...
journals.plos.org
September 15, 2025 at 7:04 PM
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
Reposted by Chen Davidovich
Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...
VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing
Schulten et al. show that VEL polymerization domains produce higher-order protein
assemblies to maintain chromatin association of Polycomb proteins, enabling a stable
epigenetic switch at the floral r...
www.cell.com
August 26, 2025 at 6:04 PM
Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...
Reposted by Chen Davidovich
Finally out on @devbiol.bsky.social: we find that Epop mutant mice have near-perfect Polycomb phenotype (orderly posterior shift of vertebral identity🩻) linked to accelerated HOX clock⏰.
Bonus: Epop has maternal effect!
Study co-led by the the labs of Bernie Payer and @lucianodicroce.bsky.social
Bonus: Epop has maternal effect!
Study co-led by the the labs of Bernie Payer and @lucianodicroce.bsky.social
The PRC2-associated factor EPOP is required for Hox gene regulation during axial development in mice
The Polycomb repressive complex 2 (PRC2) is an essential modulator of gene repression. We previously reported that, in mouse embryonic stem cells, PRC…
www.sciencedirect.com
August 25, 2025 at 7:44 PM
Finally out on @devbiol.bsky.social: we find that Epop mutant mice have near-perfect Polycomb phenotype (orderly posterior shift of vertebral identity🩻) linked to accelerated HOX clock⏰.
Bonus: Epop has maternal effect!
Study co-led by the the labs of Bernie Payer and @lucianodicroce.bsky.social
Bonus: Epop has maternal effect!
Study co-led by the the labs of Bernie Payer and @lucianodicroce.bsky.social
Reposted by Chen Davidovich
🚨New preprint from the lab🚨
🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK.
www.biorxiv.org/content/10.1...
🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK.
www.biorxiv.org/content/10.1...
Mechanistic and Epigenetic Partitioning of Lamina-Associated Chromatin Revealed by a Genome-Wide Imaging Screen
The nuclear periphery is a key site for heterochromatin organization in eukaryotic cells, where lamina-associated domains (LADs) promote transcriptional repression and genome stability. Despite their ...
www.biorxiv.org
August 14, 2025 at 7:01 PM
🚨New preprint from the lab🚨
🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK.
www.biorxiv.org/content/10.1...
🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK.
www.biorxiv.org/content/10.1...
Reposted by Chen Davidovich
Excited to share our work on the specificity of PRC2 subcomplexes in stem cell and differentiation. We show that PRC2.1 and PRC2.2 exhibit distinct H3K27 methylation specificity in human pluripotent stem cells and opposing role in differentiation. Now online at Mol Cell: www.cell.com/molecular-ce...
Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation
Much et al. reveal that the PRC2 subcomplexes PRC2.1 and PRC2.2 play distinct roles
in the epigenetic repression of developmental genes in human stem cells. Interactions
between the PRC2 core and its ...
www.cell.com
August 12, 2025 at 3:38 PM
Excited to share our work on the specificity of PRC2 subcomplexes in stem cell and differentiation. We show that PRC2.1 and PRC2.2 exhibit distinct H3K27 methylation specificity in human pluripotent stem cells and opposing role in differentiation. Now online at Mol Cell: www.cell.com/molecular-ce...
Reposted by Chen Davidovich
We are excited to share our new preprint demonstrating that nucleic acid interactions with SUZ12 constrain PRC2 activity, establishing a kinetic buffer essential for targeted gene silencing and revealing vulnerabilities in diffuse midline gliomas.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
July 23, 2025 at 11:38 PM
We are excited to share our new preprint demonstrating that nucleic acid interactions with SUZ12 constrain PRC2 activity, establishing a kinetic buffer essential for targeted gene silencing and revealing vulnerabilities in diffuse midline gliomas.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Chen Davidovich
How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
July 22, 2025 at 6:42 PM
How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions.
www.cell.com/molecular-ce...
www.cell.com/molecular-ce...
Reposted by Chen Davidovich
Register for the Australian Cell Cycle, DNA Repair & Telomere Meeting in beautiful Melbourne October 19-22, 2025. Plenty of slots for selected abstracts and posters. High praise last time from Piotr Sicinski: "en par with a Gordon conference for science and interaction"
www.australiancellcycle.org
www.australiancellcycle.org
Australian Cell Cycle, DNA repair and Telomere Meeting
October 20-22, 2025
www.australiancellcycle.org
July 22, 2025 at 10:42 AM
Register for the Australian Cell Cycle, DNA Repair & Telomere Meeting in beautiful Melbourne October 19-22, 2025. Plenty of slots for selected abstracts and posters. High praise last time from Piotr Sicinski: "en par with a Gordon conference for science and interaction"
www.australiancellcycle.org
www.australiancellcycle.org
Reposted by Chen Davidovich
Happy to announce a new preprint from my lab looking in to the establishment of polycomb domains in early fly development and contributions from pioneer factors Zelda and GAGA-factor.
Nucleation-dependent propagation of Polycomb modifications emerges during the Drosophila maternal to zygotic transition https://www.biorxiv.org/content/10.1101/2025.07.02.662854v1
July 3, 2025 at 9:44 PM
Happy to announce a new preprint from my lab looking in to the establishment of polycomb domains in early fly development and contributions from pioneer factors Zelda and GAGA-factor.
Reposted by Chen Davidovich
✨Excited to share my first postdoc paper on chromatin remodeler, MORC2 ✨
Using #cryoEM & #singlemolecule imaging, we reveal how MORC2 compacts DNA 🔬🧬
Thanks to all collaborators from @wehi-research.bsky.social @ccemmp-outreach.bsky.social Uni Melb, Monash Uni, Seoul National Uni and Texas Uni!
Using #cryoEM & #singlemolecule imaging, we reveal how MORC2 compacts DNA 🔬🧬
Thanks to all collaborators from @wehi-research.bsky.social @ccemmp-outreach.bsky.social Uni Melb, Monash Uni, Seoul National Uni and Texas Uni!
Researchers learned a function of enzyme MORC2, that helps organise DNA and turn off genes when not needed. Mutations in MORC2 cause Charcot-Marie-Tooth disease, a rare condition that weakens muscles. These findings could lead to new treatments.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 2, 2025 at 6:19 AM
✨Excited to share my first postdoc paper on chromatin remodeler, MORC2 ✨
Using #cryoEM & #singlemolecule imaging, we reveal how MORC2 compacts DNA 🔬🧬
Thanks to all collaborators from @wehi-research.bsky.social @ccemmp-outreach.bsky.social Uni Melb, Monash Uni, Seoul National Uni and Texas Uni!
Using #cryoEM & #singlemolecule imaging, we reveal how MORC2 compacts DNA 🔬🧬
Thanks to all collaborators from @wehi-research.bsky.social @ccemmp-outreach.bsky.social Uni Melb, Monash Uni, Seoul National Uni and Texas Uni!
Reposted by Chen Davidovich
Lentivirus massively parallel reporter assays integrate & enrich for specific sequences in the genome. We utilize this to test their epigenetic modifications & open chromatin alongside their regulatory activity. Amazing work by Zicong Zhang, Fumitaka Inoue & others.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA
Cis-regulatory elements (CREs) have a major effect on phenotypes including disease. They are identified in a genome-wide manner by analyzing the binding of transcription factors (TFs), various co-fact...
www.biorxiv.org
July 1, 2025 at 3:13 PM
Lentivirus massively parallel reporter assays integrate & enrich for specific sequences in the genome. We utilize this to test their epigenetic modifications & open chromatin alongside their regulatory activity. Amazing work by Zicong Zhang, Fumitaka Inoue & others.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Chen Davidovich
New from our lab & @harrisonflylab.bsky.social: Drosophila models of H3 K27M & EZHIP reveal conserved chromatin regulators that buffer PRC2 inhibition. An in vivo screen highlights how developmental defects can be rescued despite global H3K27me3 loss.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
May 27, 2025 at 3:29 PM
New from our lab & @harrisonflylab.bsky.social: Drosophila models of H3 K27M & EZHIP reveal conserved chromatin regulators that buffer PRC2 inhibition. An in vivo screen highlights how developmental defects can be rescued despite global H3K27me3 loss.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Reposted by Chen Davidovich
Excited our paper is out in Cell @cp-cell.bsky.social!
🧬⚡ DNA photo-crosslinking proteomics in living cells
🎯 Pinpoints protein-DNA interactions to single amino acids
🌎 Globally quantifies DNA binding for >1800 proteins at a timescale of minutes
🔗 www.cell.com/cell/fulltex...
🧵
🧬⚡ DNA photo-crosslinking proteomics in living cells
🎯 Pinpoints protein-DNA interactions to single amino acids
🌎 Globally quantifies DNA binding for >1800 proteins at a timescale of minutes
🔗 www.cell.com/cell/fulltex...
🧵
The human proteome with direct physical access to DNA
Zero-distance photo-crosslinking reveals direct protein-DNA interactions in living
cells, enabling quantitative analysis of the DNA-interacting proteome on a timescale
of minutes with single-amino-aci...
www.cell.com
May 23, 2025 at 7:06 AM
Excited our paper is out in Cell @cp-cell.bsky.social!
🧬⚡ DNA photo-crosslinking proteomics in living cells
🎯 Pinpoints protein-DNA interactions to single amino acids
🌎 Globally quantifies DNA binding for >1800 proteins at a timescale of minutes
🔗 www.cell.com/cell/fulltex...
🧵
🧬⚡ DNA photo-crosslinking proteomics in living cells
🎯 Pinpoints protein-DNA interactions to single amino acids
🌎 Globally quantifies DNA binding for >1800 proteins at a timescale of minutes
🔗 www.cell.com/cell/fulltex...
🧵
Reposted by Chen Davidovich
Now published! Big congrats to first author @gginell.bsky.social
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...
May 23, 2025 at 11:31 AM
Now published! Big congrats to first author @gginell.bsky.social
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...