Epigenome Technologies
epigenometech.bsky.social
Epigenome Technologies
@epigenometech.bsky.social
Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
Learn how we used Droplet Paired-Tag to assess RNA expression and his mods in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

bit.ly/4kgWMF3
November 11, 2025 at 4:20 PM
Epigenetics Update - Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity go.nature.com/4nFnd8s

#Epigenetics #DNAm #T1D #Diabetes
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Perfect for cancer, immunology, and aging research; epigenometech.com
Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity - Nature Metabolism
Through an epigenome-wide blood analysis in children of mothers with or without type 1 diabetes, the authors identify epigenetic modifications of type 1 diabetes susceptibility loci through which mate...
go.nature.com
November 11, 2025 at 12:19 PM
Epigenetics Update - p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer bit.ly/47EldY9

#Epigenetics #StemCells #BreastCancer
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Gain deeper insights into gene regulation; epigenometech.com
p53 regulates the expression of histone modifiers to restrict stemness and maintain differentiated luminal identity in breast cancer | PNAS
Breast cancer is the leading cause of death in women under 50. The majority of breast cancers are estrogen receptor α-positive (ER+) and are common...
bit.ly
November 11, 2025 at 8:55 AM
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics

bit.ly/4kgWMF3
November 10, 2025 at 4:33 PM
Epigenetics Update - Epigenetically driven and early immune evasion in colorectal cancer evolution go.nature.com/47HwjeU

Andrea Sottoriva and Trevor A. Graham reporting in Nat Genet

#Epigenetics #ColorectalCancer #Cancer
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Discover the breakthrough at epigenometech.com
November 10, 2025 at 12:52 PM
Epigenetics Update - A unified framework for systematic curation and evaluation of aging biomarkers go.nature.com/4nYcl61

Mahdi Moqri and Vadim N. Gladyshev reporting in Nat Aging

#Epigenetics #Aging #Biomarkers
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High-resolution insights without cell sorting; epigenometech.com
November 10, 2025 at 9:08 AM
Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

bit.ly/3HWFoaw
November 7, 2025 at 3:50 PM
Epigenetics Update - Repair of DNA double-strand breaks leaves heritable impairment to genome function bit.ly/4oVUjC8

Susanne Bantele and Jiri Lukas reporting in Science

#Epigenetics #DNAdamage #Chromatin

Perfect for cancer, immunology, and aging research; epigenometech.com
Repair of DNA double-strand breaks leaves heritable impairment to genome function
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
bit.ly
November 7, 2025 at 11:17 AM
Epigenetics Update - Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions bit.ly/3LnWy2G

James O.J. Davies (University of Oxford) in Cell

#Epigenetics #Chromatin #CREs
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Gain deeper insights into gene regulation; epigenometech.com
November 7, 2025 at 9:03 AM
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks

#Epigenetics #SingleCell #PairedTag #Multiomics

Find out more at: bit.ly/4efqM1Y
November 6, 2025 at 4:35 PM
Epigenetics Update – Sensory input, sex and function shape hypothalamic cell type development go.nature.com/43he3rt

Catherine Dulac (Harvard University) reporting in Nature

#Epigenetics #Chromatin #Multiomics
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Empower your research with high-res epigenetic insights at epigenometech.com
November 6, 2025 at 12:11 PM
Epigenetics Update - Spatial dynamics of brain development and neuroinflammation go.nature.com/49AJu3Q

Gonçalo Castelo-Branco and Rong Fan reporting in Nature

#Epigenetics #Multiomics #BrainDevelopment #Neuroinflammation

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Discover the breakthrough at epigenometech.com
November 6, 2025 at 8:16 AM
Reposted by Epigenome Technologies
Our latest paper has just been published in Cell!

doi.org/10.1016/j.ce...

We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.
November 5, 2025 at 5:20 PM
New Epigenome Technologies Blog post! bit.ly/4opVUQJ

"Single-cell 3D Genome Atlases Describing Cancer Progression Reveal Stage-specific Alterations and Novel Biomarkers"

#Epigenetics #Blog #EpigenomeTech #SingleCell #Cancer

See more at: epigenometech.com/blog/index.h...
November 5, 2025 at 6:17 PM
Reposted by Epigenome Technologies
Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com

www.nature.com/articles/s41...
Spatial dynamics of brain development and neuroinflammation - Nature
A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.
www.nature.com
November 5, 2025 at 4:03 PM
Epigenetics Update - A PHF19-YTHDC1 condensate switches EZH2-mediated gene suppression to activation for prostate cancer progression bit.ly/3WldyJd

#Epigenetics #Chromatin #ProstateCancer #Cancer
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High-resolution insights without cell sorting; epigenometech.com
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
bit.ly
November 5, 2025 at 1:02 PM
Epigenetics Update - Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements bit.ly/4ocNpsi

#Epigenetics #DNAm #DNAme #CpGIslands
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Empower your research with high-res epigenetic insights at epigenometech.com
November 5, 2025 at 9:15 AM
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service

Our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4kPxe2i
November 4, 2025 at 5:29 PM
Epigenetics Update - Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation bit.ly/490cQIU

Sofia-Iris Bibli in Cell Metab

#Epigenetics #Metabolsim #HistoneAcetylation
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Perfect for cancer, immunology, and aging; epigenometech.com
November 4, 2025 at 12:31 PM
Epigenetics Update - Mechanisms of DNMT3A–3L-mediated de novo DNA methylation on chromatin go.nature.com/3X4LVUP

Peter A. Jones and Ting-Hai Xu reporting in NSMB

#Epigenetics #DNAm #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
November 4, 2025 at 9:02 AM
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit

Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4lquJDv
November 3, 2025 at 4:38 PM
Epigenetics Update - N6-methyladenosine on L1PA governs the trans-silencing of LTRs and restrains totipotency in naive human embryonic stem cells bit.ly/4quXN05

#Epigenetics #StemCells #ESCs #Totipotency
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Discover the breakthrough at epigenometech.com
November 3, 2025 at 12:33 PM
Epigenetics Review - Epigenetic regulation of T cell exhaustion in cancer go.nature.com/4ohBOrZ

Ben Youngblood (St. Jude Children's Research Hospital) reporting in Nat Rev Cancer

#Epigenetics #Review #TCellExhaustion #Cancer
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High-resolution insights without cell sorting; epigenometech.com
Epigenetic regulation of T cell exhaustion in cancer - Nature Reviews Cancer
Transcriptional and epigenetic mechanisms governing T cell exhaustion substantially impact immunotherapy effectiveness. In this Review, Kang et al. outline epigenetic regulatory programmes that i...
go.nature.com
November 3, 2025 at 9:01 AM
Our expansion of single-cell epigenetics assays continues!

The Epigenome Technologies scCUT&Tag assay is now compatible with the BD Rhapsody platform

Learn more here: lnkd.in/g3YqPrWY

#epigenetics #BDrhapsody #CUTandTag #Chromatin #multiomics #singlecell #CUTandRUN #ChIPseq #ATACseq
October 31, 2025 at 4:50 PM
Epigenetics Update - Epigenetic dysregulation in aged muscle stem cells drives mesenchymal progenitor expansion via IL-6 and Spp1 signaling go.nature.com/3JshDZ8

#Epigenetics #StemCells #MuscleStemCells #Aging
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Perfect for cancer, immunology, and aging research; epigenometech.com
October 31, 2025 at 12:18 PM