Epigenome Technologies
@epigenometech.bsky.social
Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
January 2, 2026 at 4:45 PM
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers
bit.ly/4kgWMF3
Epigenetics Review - Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications bit.ly/4aY7a39
Linghua Wang reporting in Cancer Cell
#Epigenetics #Review #SpatialOmics
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Discover the breakthrough at epigenometech.com
Linghua Wang reporting in Cancer Cell
#Epigenetics #Review #SpatialOmics
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Discover the breakthrough at epigenometech.com
January 2, 2026 at 1:30 PM
Epigenetics Review - Spatial omics at the forefront: emerging technologies, analytical innovations, and clinical applications bit.ly/4aY7a39
Linghua Wang reporting in Cancer Cell
#Epigenetics #Review #SpatialOmics
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Discover the breakthrough at epigenometech.com
Linghua Wang reporting in Cancer Cell
#Epigenetics #Review #SpatialOmics
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Discover the breakthrough at epigenometech.com
Epigenetics Update - BRD2 bridges TFIID and MOF-H4K16ac-containing nucleosomes to promote transcriptional initiation bit.ly/497Jcj2
Bin Zheng and Ali Shilatifard reporting in Mol Cell
#Epigenetics #Acetylation #BRD2 #MOF
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High-resolution insights without cell sorting; epigenometech.com
Bin Zheng and Ali Shilatifard reporting in Mol Cell
#Epigenetics #Acetylation #BRD2 #MOF
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High-resolution insights without cell sorting; epigenometech.com
January 2, 2026 at 8:56 AM
Epigenetics Update - BRD2 bridges TFIID and MOF-H4K16ac-containing nucleosomes to promote transcriptional initiation bit.ly/497Jcj2
Bin Zheng and Ali Shilatifard reporting in Mol Cell
#Epigenetics #Acetylation #BRD2 #MOF
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High-resolution insights without cell sorting; epigenometech.com
Bin Zheng and Ali Shilatifard reporting in Mol Cell
#Epigenetics #Acetylation #BRD2 #MOF
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High-resolution insights without cell sorting; epigenometech.com
New Epigenome Technologies Blog post! bit.ly/4ptPJLq
“How Does Stress Induce Cellular Adaptation: Can Epigenetic Alterations Influence Transcription and Translation?”
Based on a Nature Cell Biology paper from Ola Larsson and Lynne-Marie Postovit
#Epigenetics #Stress #TSSSwitching
“How Does Stress Induce Cellular Adaptation: Can Epigenetic Alterations Influence Transcription and Translation?”
Based on a Nature Cell Biology paper from Ola Larsson and Lynne-Marie Postovit
#Epigenetics #Stress #TSSSwitching
December 31, 2025 at 4:36 PM
New Epigenome Technologies Blog post! bit.ly/4ptPJLq
“How Does Stress Induce Cellular Adaptation: Can Epigenetic Alterations Influence Transcription and Translation?”
Based on a Nature Cell Biology paper from Ola Larsson and Lynne-Marie Postovit
#Epigenetics #Stress #TSSSwitching
“How Does Stress Induce Cellular Adaptation: Can Epigenetic Alterations Influence Transcription and Translation?”
Based on a Nature Cell Biology paper from Ola Larsson and Lynne-Marie Postovit
#Epigenetics #Stress #TSSSwitching
Epigenetics Update - Epigenetic and transcriptomic alterations precede amyloidosis in the Alzheimer’s disease AppNL-G-F knock-in mouse model go.nature.com/4plDdgS
#Epigenetics #Chromatin #Alzheimers
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High-resolution insights without cell sorting; epigenometech.com
#Epigenetics #Chromatin #Alzheimers
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High-resolution insights without cell sorting; epigenometech.com
December 31, 2025 at 12:37 PM
Epigenetics Update - Epigenetic and transcriptomic alterations precede amyloidosis in the Alzheimer’s disease AppNL-G-F knock-in mouse model go.nature.com/4plDdgS
#Epigenetics #Chromatin #Alzheimers
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High-resolution insights without cell sorting; epigenometech.com
#Epigenetics #Chromatin #Alzheimers
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High-resolution insights without cell sorting; epigenometech.com
Epigenetics Update - H2AK119ub dynamics control hair follicle stem cell quiescence go.nature.com/44GKO1X
Elena Ezhkova (Icahn School of Medicine at Mount Sinai) in Nat Commun
#Epigenetics #StemCells #H2AK119ub
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Empower your research with high-res epigenetic insights at epigenometech.com
Elena Ezhkova (Icahn School of Medicine at Mount Sinai) in Nat Commun
#Epigenetics #StemCells #H2AK119ub
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Empower your research with high-res epigenetic insights at epigenometech.com
December 31, 2025 at 9:13 AM
Epigenetics Update - H2AK119ub dynamics control hair follicle stem cell quiescence go.nature.com/44GKO1X
Elena Ezhkova (Icahn School of Medicine at Mount Sinai) in Nat Commun
#Epigenetics #StemCells #H2AK119ub
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Empower your research with high-res epigenetic insights at epigenometech.com
Elena Ezhkova (Icahn School of Medicine at Mount Sinai) in Nat Commun
#Epigenetics #StemCells #H2AK119ub
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Empower your research with high-res epigenetic insights at epigenometech.com
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
December 30, 2025 at 4:33 PM
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
bit.ly/4kgWMF3
Epigenetics Update - DNA methylation shapes transcription factor binding beyond canonical CpG contexts bit.ly/4s54ruK
Ariel Afek (Weizmann Institute of Science) reporting in PNAS
#Epigenetics #DNAm
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Perfect for cancer, immunology, and aging research; epigenometech.com
Ariel Afek (Weizmann Institute of Science) reporting in PNAS
#Epigenetics #DNAm
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Perfect for cancer, immunology, and aging research; epigenometech.com
December 30, 2025 at 12:36 PM
Epigenetics Update - DNA methylation shapes transcription factor binding beyond canonical CpG contexts bit.ly/4s54ruK
Ariel Afek (Weizmann Institute of Science) reporting in PNAS
#Epigenetics #DNAm
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Perfect for cancer, immunology, and aging research; epigenometech.com
Ariel Afek (Weizmann Institute of Science) reporting in PNAS
#Epigenetics #DNAm
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Perfect for cancer, immunology, and aging research; epigenometech.com
Epigenetics Update – Direct recruitment of TONSOKU by the N-terminal tails of histone variants H2A.X and H2A.W coordinates DNA repair bit.ly/4qhWgJP
#Epigenetics #DNADamage #DNARepair #HistoneVariants
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Gain deeper insights into gene regulation; epigenometech.com
#Epigenetics #DNADamage #DNARepair #HistoneVariants
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Gain deeper insights into gene regulation; epigenometech.com
December 30, 2025 at 8:52 AM
Epigenetics Update – Direct recruitment of TONSOKU by the N-terminal tails of histone variants H2A.X and H2A.W coordinates DNA repair bit.ly/4qhWgJP
#Epigenetics #DNADamage #DNARepair #HistoneVariants
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Gain deeper insights into gene regulation; epigenometech.com
#Epigenetics #DNADamage #DNARepair #HistoneVariants
---
Gain deeper insights into gene regulation; epigenometech.com
Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
December 29, 2025 at 5:01 PM
Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
#Epigenetics #SingleCell #PairedTag #Multiomics
bit.ly/3HWFoaw
Epigenetics Update - Germline epigenome editing identifies H3K9me3 as a mediator of intergenerational DNA methylation recovery in mice go.nature.com/4sd4NQ1
Takuro Horii and Izuho Hatada in Nat Commun
#Epigenetics #H3K9me3 #DNAme #IEI
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Discover the breakthrough at epigenometech.com
Takuro Horii and Izuho Hatada in Nat Commun
#Epigenetics #H3K9me3 #DNAme #IEI
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Discover the breakthrough at epigenometech.com
December 29, 2025 at 1:08 PM
Epigenetics Update - Germline epigenome editing identifies H3K9me3 as a mediator of intergenerational DNA methylation recovery in mice go.nature.com/4sd4NQ1
Takuro Horii and Izuho Hatada in Nat Commun
#Epigenetics #H3K9me3 #DNAme #IEI
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Discover the breakthrough at epigenometech.com
Takuro Horii and Izuho Hatada in Nat Commun
#Epigenetics #H3K9me3 #DNAme #IEI
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Discover the breakthrough at epigenometech.com
Epigenetics Update - Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptopathy in encephalitis bit.ly/48VsIMn
Doron Merkler (University of Geneva) reported in Neuron
#Epigenetics #Encephalitis #Interferongamma
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High-resolution insights without cell sorting; epigenometech.com
Doron Merkler (University of Geneva) reported in Neuron
#Epigenetics #Encephalitis #Interferongamma
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High-resolution insights without cell sorting; epigenometech.com
Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptopathy in encephalitis
Shammas et al. show a neuronal epigenetic remodeling during CNS encephalitis. This
program involves IFNγ-driven persistent reduction in TF-binding site accessibility,
linked to long-lasting reduction ...
bit.ly
December 29, 2025 at 9:03 AM
Epigenetics Update - Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptopathy in encephalitis bit.ly/48VsIMn
Doron Merkler (University of Geneva) reported in Neuron
#Epigenetics #Encephalitis #Interferongamma
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High-resolution insights without cell sorting; epigenometech.com
Doron Merkler (University of Geneva) reported in Neuron
#Epigenetics #Encephalitis #Interferongamma
---
High-resolution insights without cell sorting; epigenometech.com
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
December 26, 2025 at 5:04 PM
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
#Epigenetics #SingleCell #PairedTag #Multiomics
Find out more at: bit.ly/4efqM1Y
Epigenetics Update – Hepatic adaptation to chronic metabolic stress primes tumorigenesis bit.ly/4sak6ZG
Wolfram Goessling, Ömer H. Yilmaz, and Alex K. Shalek reporting in Cell
#Epigenetics #Metabolism #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
Wolfram Goessling, Ömer H. Yilmaz, and Alex K. Shalek reporting in Cell
#Epigenetics #Metabolism #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
December 26, 2025 at 1:15 PM
Epigenetics Update – Hepatic adaptation to chronic metabolic stress primes tumorigenesis bit.ly/4sak6ZG
Wolfram Goessling, Ömer H. Yilmaz, and Alex K. Shalek reporting in Cell
#Epigenetics #Metabolism #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
Wolfram Goessling, Ömer H. Yilmaz, and Alex K. Shalek reporting in Cell
#Epigenetics #Metabolism #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetics Update - Two distinct chromatin modules regulate proinflammatory gene expression go.nature.com/45oJKQu
Karsten Rippe (DKFZ/BioQuant) reporting in Nat Cell Biol
#Epigenetics #Chromatin #Inflammation
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Discover the breakthrough at epigenometech.com
Karsten Rippe (DKFZ/BioQuant) reporting in Nat Cell Biol
#Epigenetics #Chromatin #Inflammation
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Discover the breakthrough at epigenometech.com
December 26, 2025 at 9:29 AM
Epigenetics Update - Two distinct chromatin modules regulate proinflammatory gene expression go.nature.com/45oJKQu
Karsten Rippe (DKFZ/BioQuant) reporting in Nat Cell Biol
#Epigenetics #Chromatin #Inflammation
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Discover the breakthrough at epigenometech.com
Karsten Rippe (DKFZ/BioQuant) reporting in Nat Cell Biol
#Epigenetics #Chromatin #Inflammation
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Discover the breakthrough at epigenometech.com
New Epigenome Technologies Blog post! bit.ly/4s8hD21
"Sex-bias in Multiple Sclerosis: Is There an Epigenetic Reason?"
Based on a Science Translational Medicine paper from Rhonda R. Voskuhl (University of California, Los Angeles)
#Epigenetics #MultipleSclerosis #SexBias
"Sex-bias in Multiple Sclerosis: Is There an Epigenetic Reason?"
Based on a Science Translational Medicine paper from Rhonda R. Voskuhl (University of California, Los Angeles)
#Epigenetics #MultipleSclerosis #SexBias
December 24, 2025 at 4:32 PM
New Epigenome Technologies Blog post! bit.ly/4s8hD21
"Sex-bias in Multiple Sclerosis: Is There an Epigenetic Reason?"
Based on a Science Translational Medicine paper from Rhonda R. Voskuhl (University of California, Los Angeles)
#Epigenetics #MultipleSclerosis #SexBias
"Sex-bias in Multiple Sclerosis: Is There an Epigenetic Reason?"
Based on a Science Translational Medicine paper from Rhonda R. Voskuhl (University of California, Los Angeles)
#Epigenetics #MultipleSclerosis #SexBias
Epigenetics Update - MAT2A promotes atherosclerotic plaque vulnerability by mediating epigenetic reprogramming of macrophages go.nature.com/44xIxpN
Study reported in Nat Commun
#Epigenetics #MAT2A #Atherosclerosis
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High-resolution insights without cell sorting; epigenometech.com
Study reported in Nat Commun
#Epigenetics #MAT2A #Atherosclerosis
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High-resolution insights without cell sorting; epigenometech.com
December 24, 2025 at 1:07 PM
Epigenetics Update - MAT2A promotes atherosclerotic plaque vulnerability by mediating epigenetic reprogramming of macrophages go.nature.com/44xIxpN
Study reported in Nat Commun
#Epigenetics #MAT2A #Atherosclerosis
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High-resolution insights without cell sorting; epigenometech.com
Study reported in Nat Commun
#Epigenetics #MAT2A #Atherosclerosis
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High-resolution insights without cell sorting; epigenometech.com
Epigenetic Perspective - Do we actually need aging clocks? go.nature.com/499rtrD
Dmitrii Kriukov reporting in Nature Aging
#Epigenetics #Aging #AgingClocks
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Empower your research with high-res epigenetic insights at epigenometech.com
Dmitrii Kriukov reporting in Nature Aging
#Epigenetics #Aging #AgingClocks
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Empower your research with high-res epigenetic insights at epigenometech.com
December 24, 2025 at 8:24 AM
Epigenetic Perspective - Do we actually need aging clocks? go.nature.com/499rtrD
Dmitrii Kriukov reporting in Nature Aging
#Epigenetics #Aging #AgingClocks
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Empower your research with high-res epigenetic insights at epigenometech.com
Dmitrii Kriukov reporting in Nature Aging
#Epigenetics #Aging #AgingClocks
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Empower your research with high-res epigenetic insights at epigenometech.com
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
December 23, 2025 at 5:55 PM
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Our expert scientists run the entire workflow on your samples - from preparation to data analysis
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4kPxe2i
Epigenetic Update - Interphase chromosome conformation is specified by distinct folding programmes inherited through mitotic chromosomes or the cytoplasm go.nature.com/494u467
#Epigenetics #Chromatin #EpigeneticInheritance
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Perfect for cancer, immunology, and aging research; epigenometech.com
#Epigenetics #Chromatin #EpigeneticInheritance
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Perfect for cancer, immunology, and aging research; epigenometech.com
December 23, 2025 at 1:02 PM
Epigenetic Update - Interphase chromosome conformation is specified by distinct folding programmes inherited through mitotic chromosomes or the cytoplasm go.nature.com/494u467
#Epigenetics #Chromatin #EpigeneticInheritance
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Perfect for cancer, immunology, and aging research; epigenometech.com
#Epigenetics #Chromatin #EpigeneticInheritance
---
Perfect for cancer, immunology, and aging research; epigenometech.com
Epigenetics Update - An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes go.nature.com/49dB6GW (News - bit.ly/3N9XW9O)
#Epigenetics #Chromatin #EpigeneticClocks #Aging
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Gain deeper insights into gene regulation; epigenometech.com
#Epigenetics #Chromatin #EpigeneticClocks #Aging
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Gain deeper insights into gene regulation; epigenometech.com
December 23, 2025 at 8:49 AM
Epigenetics Update - An unbiased comparison of 14 epigenetic clocks in relation to 174 incident disease outcomes go.nature.com/49dB6GW (News - bit.ly/3N9XW9O)
#Epigenetics #Chromatin #EpigeneticClocks #Aging
---
Gain deeper insights into gene regulation; epigenometech.com
#Epigenetics #Chromatin #EpigeneticClocks #Aging
---
Gain deeper insights into gene regulation; epigenometech.com
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
December 22, 2025 at 5:22 PM
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®
#Epigenetics #SingleCell #CUTandTag
Find out more at: bit.ly/4lquJDv
Epigenetics Update - H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations bit.ly/459lS3k
Robert Schneider (Helmholtz München) in Mol Cell
#Epigenetics #Chromatin #Metabolism
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Discover the breakthrough at epigenometech.com
Robert Schneider (Helmholtz München) in Mol Cell
#Epigenetics #Chromatin #Metabolism
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Discover the breakthrough at epigenometech.com
December 22, 2025 at 12:57 PM
Epigenetics Update - H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations bit.ly/459lS3k
Robert Schneider (Helmholtz München) in Mol Cell
#Epigenetics #Chromatin #Metabolism
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Discover the breakthrough at epigenometech.com
Robert Schneider (Helmholtz München) in Mol Cell
#Epigenetics #Chromatin #Metabolism
---
Discover the breakthrough at epigenometech.com
Epigenetics Update - Chromatin buffers torsional stress during transcription bit.ly/44FZdvo
Michelle D. Wang (Cornell University) reporting in Science
#Epigenetics #Chromatin #Stress
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High-resolution insights without cell sorting; epigenometech.com
Michelle D. Wang (Cornell University) reporting in Science
#Epigenetics #Chromatin #Stress
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High-resolution insights without cell sorting; epigenometech.com
Chromatin buffers torsional stress during transcription
During eukaryotic transcription, Pol II must overcome nucleosome obstacles and, because of DNA’s helical structure, must also rotate relative to DNA, generating torsional stress. However, there is lim...
bit.ly
December 22, 2025 at 8:57 AM
Epigenetics Update - Chromatin buffers torsional stress during transcription bit.ly/44FZdvo
Michelle D. Wang (Cornell University) reporting in Science
#Epigenetics #Chromatin #Stress
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High-resolution insights without cell sorting; epigenometech.com
Michelle D. Wang (Cornell University) reporting in Science
#Epigenetics #Chromatin #Stress
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High-resolution insights without cell sorting; epigenometech.com
Reposted by Epigenome Technologies
January 7th 2-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
December 19, 2025 at 8:17 PM
January 7th 2-1pm in MSRBIII or online, #DukeSCIRIP seminar series continues!
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...
@epigenometech.bsky.social's Chris Hartle will be presenting the talk '‘Deciphering Single-Cell Chromatin Landscapes in the Human Immune System: A First Look’ 🧬
For more information: dmpi.duke.edu/duke-single-...