Timothy Bredy
@twbredy.bsky.social
Professor | Director, UQ Centre for RNA in Neuroscience | Queensland Brain Institute | Noncoding RNA and memory; RNA and DNA modification in the brain.
Pinned
RNA Technologies and Therapeutics for Neuroscience - Neuroscience School of Advanced Studies
RNA Technologies and Therapeutics for Neuroscience May 30-June 7, 2026 Director: Timothy Bredy University of Queensland, Australia Faculty: Gene Yeo, University of California, San Diego, USA Eric ...
www.neurosas.org
Alright people, re-upping this on your feed. Space is limited so please register soon!
www.neurosas.org/advanced-cou...
www.neurosas.org/advanced-cou...
Here’s awesome bit of technical work by PhD student Josh Davies in Paul Marshall’s lab at ANU. Proud to part of it. Sex differences run deep when you look at the brain with high resolution.
Light-inducible proximity labelling in vivo captures sex-specific RNA at excitatory synapses https://www.biorxiv.org/content/10.64898/2026.01.28.702434v1
January 29, 2026 at 10:29 PM
Here’s awesome bit of technical work by PhD student Josh Davies in Paul Marshall’s lab at ANU. Proud to part of it. Sex differences run deep when you look at the brain with high resolution.
Reposted by Timothy Bredy
Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6...
Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6
Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6
www.biorxiv.org
January 28, 2026 at 1:24 AM
Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6...
Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6
Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6
Another outstanding RNA meeting!
Sign up now for the EMBO Workshop "#RNA metabolism: Perspective from physiology to brain disorder" in Darjeeling, India, 25–28 October 2026.
Deadline: 15 May 2026
https://meetings.embo.org/event/26-rna-metabolism
#EMBOrnaMetabolism #RNAsky #LifeSciences #research #conference #EMBOevents 🧪
Deadline: 15 May 2026
https://meetings.embo.org/event/26-rna-metabolism
#EMBOrnaMetabolism #RNAsky #LifeSciences #research #conference #EMBOevents 🧪
January 27, 2026 at 3:31 PM
Another outstanding RNA meeting!
Reposted by Timothy Bredy
My perspective in @thetransmitter.bsky.social on why emotion research feels stuck and how we might move forward—by focusing on how the brain uses internal brain models to shape emotional processing across species. www.thetransmitter.org/emotion/why-...
Why emotion research is stuck—and how to move it forward
Studying how organisms infer indirect threats and understand changing contexts can establish a common framework that bridges species and levels of analysis.
www.thetransmitter.org
January 26, 2026 at 11:18 AM
My perspective in @thetransmitter.bsky.social on why emotion research feels stuck and how we might move forward—by focusing on how the brain uses internal brain models to shape emotional processing across species. www.thetransmitter.org/emotion/why-...
Reposted by Timothy Bredy
We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT
January 18, 2026 at 2:30 PM
We are looking for a postdoc to work on mechanisms of #RNA decay in cancer using #cryoEM with #nanobodies and #minibinders! Please RT
Reposted by Timothy Bredy
🧪 Interested in a Cutting-Edge Molecular Neuroscience Meeting at a dream location?
Join us at the EMBO | COB Workshop on Axonal degeneration and regeneration, 18 – 22 October 2026, Onna-son, Okinawa, Japan
meetings.embo.org/event/26-axo...
Join us at the EMBO | COB Workshop on Axonal degeneration and regeneration, 18 – 22 October 2026, Onna-son, Okinawa, Japan
meetings.embo.org/event/26-axo...
January 17, 2026 at 9:45 AM
🧪 Interested in a Cutting-Edge Molecular Neuroscience Meeting at a dream location?
Join us at the EMBO | COB Workshop on Axonal degeneration and regeneration, 18 – 22 October 2026, Onna-son, Okinawa, Japan
meetings.embo.org/event/26-axo...
Join us at the EMBO | COB Workshop on Axonal degeneration and regeneration, 18 – 22 October 2026, Onna-son, Okinawa, Japan
meetings.embo.org/event/26-axo...
Here we go! 2026. the year I learn python and do my own dRNA analysis. Digging deep and glad to know @martinalexsmith.bsky.social, @michaelbclark.bsky.social, and all the other nanopore gurus in australia. @nanoporetech.com
January 15, 2026 at 10:51 AM
Here we go! 2026. the year I learn python and do my own dRNA analysis. Digging deep and glad to know @martinalexsmith.bsky.social, @michaelbclark.bsky.social, and all the other nanopore gurus in australia. @nanoporetech.com
This is a great read. Once again, RNA for the win.
OMG! Cells across the tree of life can swap short-lived messages encoded by RNA — missives that resemble a quick text message rather than a formal memo on letterhead.
Cells Across the Tree of Life Exchange ‘Text Messages’ Using RNA | Quanta Magazine
Long known as a messenger within cells, RNA is increasingly seen as life’s molecular communication system — even between organisms widely separated by evolution.
www.quantamagazine.org
January 12, 2026 at 7:32 AM
This is a great read. Once again, RNA for the win.
Yet another fantastic discovery surrounding cell surface RNAs and cellular function. Congrats @raflynn5.bsky.social and colleagues!
Hi everybody! I am super excited to share the work done during my PhD published in @nature today! We describe a new mechanism of self- vs. non-self RNA discrimination by showing how N-glycans shield glycoRNAs from stimulating endosomal RNA sensors www.nature.com/articles/s41...
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis - Nature
N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal network with...
www.nature.com
January 11, 2026 at 4:51 AM
Yet another fantastic discovery surrounding cell surface RNAs and cellular function. Congrats @raflynn5.bsky.social and colleagues!
RNASky! Wow this looks like a great opportunity to learn alot about RNA in the brain......
Alright people, re-upping this on your feed. Space is limited so please register soon!
www.neurosas.org/advanced-cou...
www.neurosas.org/advanced-cou...
RNA Technologies and Therapeutics for Neuroscience - Neuroscience School of Advanced Studies
RNA Technologies and Therapeutics for Neuroscience May 30-June 7, 2026 Director: Timothy Bredy University of Queensland, Australia Faculty: Gene Yeo, University of California, San Diego, USA Eric ...
www.neurosas.org
January 7, 2026 at 1:33 AM
RNASky! Wow this looks like a great opportunity to learn alot about RNA in the brain......
Alright people, re-upping this on your feed. Space is limited so please register soon!
www.neurosas.org/advanced-cou...
www.neurosas.org/advanced-cou...
RNA Technologies and Therapeutics for Neuroscience - Neuroscience School of Advanced Studies
RNA Technologies and Therapeutics for Neuroscience May 30-June 7, 2026 Director: Timothy Bredy University of Queensland, Australia Faculty: Gene Yeo, University of California, San Diego, USA Eric ...
www.neurosas.org
January 7, 2026 at 1:31 AM
Alright people, re-upping this on your feed. Space is limited so please register soon!
www.neurosas.org/advanced-cou...
www.neurosas.org/advanced-cou...
Reposted by Timothy Bredy
Check out our new manuscript describing the circuit-specific impact of 16p11.2, a chromosomal region linked to neurodevelopmental disorders! @UIowaNeuro @IowaNeuroPharm @Hawk_IDDRC
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 5, 2026 at 8:00 PM
Check out our new manuscript describing the circuit-specific impact of 16p11.2, a chromosomal region linked to neurodevelopmental disorders! @UIowaNeuro @IowaNeuroPharm @Hawk_IDDRC
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@jasonsynaptic.bsky.social given the relationship between ARC and HSV-1, interesting finding, n'est-ce pas?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons - Nature Neuroscience
The authors found that the Alzheimer’s disease-associated protein tau, widely considered pathogenic when hyperphosphorylated, has a natural function as part of the innate immune system in the brain an...
www.nature.com
December 30, 2025 at 4:29 AM
@jasonsynaptic.bsky.social given the relationship between ARC and HSV-1, interesting finding, n'est-ce pas?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Vaults are incredibly interesting ribonucleoprotein complexes that are vital for cellular function.
It’s out! Using cryo-ET in Dicty cells, we take a fresh in situ look at vaults. Surprisingly, we uncover vaults associated with ER and NE membranes, and find that many vaults enclose ribosomes in defined orientations, opening new avenues to their cellular function! www.biorxiv.org/lookup/conte...
December 28, 2025 at 1:39 PM
Vaults are incredibly interesting ribonucleoprotein complexes that are vital for cellular function.
Finishing 2025 on a high.
December 23, 2025 at 1:43 PM
Finishing 2025 on a high.
RNA therapeutics for the win.
A twice-weekly cocktail of three messenger RNAs can rejuvenate the weary immune systems of aged mice and boost responses to vaccination and cancer treatments
go.nature.com/497jGuw
go.nature.com/497jGuw
Restoring youth to old immune cells: mRNA therapy turns back the clock.
Nature - Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.
go.nature.com
December 21, 2025 at 1:40 PM
RNA therapeutics for the win.
Reposted by Timothy Bredy
Excited to share that this work is now published in its final form!
link.springer.com/article/10.1...
link.springer.com/article/10.1...
December 15, 2025 at 2:37 PM
Excited to share that this work is now published in its final form!
link.springer.com/article/10.1...
link.springer.com/article/10.1...
RNA transfer or cell surface RNA, take your pick…. both are awesome.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
December 11, 2025 at 12:54 AM
RNA transfer or cell surface RNA, take your pick…. both are awesome.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
$600 million… that’s how to invest in discovery. like I said awhile ago, don’t count out US science just yet…
astera.org/neuroscienti...
astera.org/neuroscienti...
Neuroscientist Doris Tsao joins Astera to lead its new neuroscience program - Astera
The Astera Institute is excited to launch a major new neuroscience research effort led by Dr. Doris Tsao, who will be joining as Chief Scientist for Astera Neuro. We seek to understand one of the deep...
astera.org
December 10, 2025 at 9:18 PM
$600 million… that’s how to invest in discovery. like I said awhile ago, don’t count out US science just yet…
astera.org/neuroscienti...
astera.org/neuroscienti...
Intrigued. Will have to reexamine our circRNA translation data!
3' to 5' Translation of Circular RNAs? https://www.biorxiv.org/content/10.64898/2025.12.08.692888v1
December 10, 2025 at 3:17 AM
Intrigued. Will have to reexamine our circRNA translation data!
My good friend, colleague and mentor, @gavanm.bsky.social speaking truth about the Australian research landscape. Will @albomp.bsky.social listen, hear, and act? The money is there in the MRFF, we need to access it immediately.
substack.com/@gavanmcnall...
substack.com/@gavanmcnall...
Gavan McNally (@gavanmcnally)
Australia is sleepwalking into scientific irrelevance
Australia is living through a dangerous contradiction: we publicly praise science while systematically dismantling the conditions required for...
substack.com
December 10, 2025 at 1:07 AM
My good friend, colleague and mentor, @gavanm.bsky.social speaking truth about the Australian research landscape. Will @albomp.bsky.social listen, hear, and act? The money is there in the MRFF, we need to access it immediately.
substack.com/@gavanmcnall...
substack.com/@gavanmcnall...