Katharina Geißler
kgeissler.bsky.social
Katharina Geißler
@kgeissler.bsky.social
PhD student @Becklab.bsky.social @Mpibp.bsky.social within @imprs-cbp.bsky.social
Reposted by Katharina Geißler
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
November 6, 2025 at 7:38 AM
Reposted by Katharina Geißler
❓What if you could peek between your tilt series ❓ We are proud to introduce cryoTIGER -- deep-learning based tilt interpolation for enhanced reconstruction in cryo-ET. A great collaboration between Turoňová lab, @becklab.bsky.social, @hummerlab.bsky.social #teamtomo www.nature.com/articles/s42...
cryoTIGER: deep-learning based tilt interpolation generator for enhanced reconstruction in cryo electron tomography - Communications Biology
Deep learning-based interpolation using cryoTIGER enhances angular sampling in cryoET, improving 3D reconstructions, particle localization, and structural recovery without increasing electron dose.
www.nature.com
October 10, 2025 at 10:35 AM
great lipid probes promising exciting studies for (membrane) cell bio, such fascinating work!
August 21, 2025 at 7:40 PM
Reposted by Katharina Geißler
The 3-decade-old competition that enabled the emergence and evaluate of AlphaFold has run out of NIH funding.

The program will be terminated in weeks.

This is terminating success.

www.science.org/content/arti...
July 3, 2025 at 12:28 PM
Reposted by Katharina Geißler
🎉 We’re absolutely thrilled: SCALE has been selected as a DFG Excellence Cluster!
A huge thank you to our incredible team—this would not have been possible without your dedication and talent. 🙌 @dfg.de
#ClustersOfExcellence #SCALEcluster 🧵
May 23, 2025 at 7:27 AM
Beautiful work by JP, Sergio, Johannes and colleagues!
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇
April 12, 2025 at 3:09 PM
Reposted by Katharina Geißler
Excited to share our latest work on nuclear pore complex scaffold integrity and its perturbation. Now out in Nature Cell Biology: rdcu.be/eg4i9
Great work by Reiya Taniguchi who just opened his own research group back in Japan! 🥳
Nuclear pores safeguard the integrity of the nuclear envelope
Nature Cell Biology - Taniguchi et al. structurally analyse nuclear pore complex architecture in situ during differentiation, which is associated with mechanical constraints on the nuclear...
rdcu.be
April 9, 2025 at 3:49 PM
Another method from our lab on biorxiv! Automated classification and removal of flawed tilts in cryo ET data
Automated Removal of Corrupted Tilts in Cryo-Electron Tomography https://www.biorxiv.org/content/10.1101/2025.03.13.642992v1
March 15, 2025 at 2:27 PM
Check out @deglushk.bsky.social 's method to measure membrane thickness in cryo electron tomograms!
In situ evidence for systematic membrane thickness variation across cellular organelles https://www.biorxiv.org/content/10.1101/2025.03.13.642912v1
March 15, 2025 at 2:25 PM