Anna Schulten
@sulteavn.bsky.social
Postdoc in Caroline Dean's lab at the John Innes Centre 🌱🧬❄️
Reposted by Anna Schulten
📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
Postdoctoral Researcher (Dr Miguel Montez) | John Innes Centre
An exciting opportunity has arisen for a Postdoctoral Researcher to join the Wellcome Trust project led by Dr Miguel Montez and hosted within the Dodd Group at the John Innes Centre.
www.jic.ac.uk
November 13, 2025 at 8:34 AM
📣 Looking for a 3-Year Postdoc @johninnescentre.bsky.social to join my Wellcome project.
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
This is a highly interdisciplinary project that explores chromatin dynamics in 🌱 plant responses across timescales, from circadian rhythms to seasonal changes
📅 Closes on 10 Dec.
www.jic.ac.uk/vacancies/36...
Reposted by Anna Schulten
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
October 31, 2025 at 10:53 AM
1/ 🚀 AEBP2 isn’t what we thought.
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
You were told that AEBP2 promotes PRC2 activity on chromatin.
We found the opposite: the most prevalent AEBP2 isoform inhibits PRC2 activity.
👉 surl.li/cgwqcq
A thread 🧵
Our paper on VEL-dependent polymerization is featured on the cover of this month's issue of @cp-molcell.bsky.social 🎉 The cover art was created by my talented friend Awesta - the result of hours of brainstorming together over video. Great fun teaming up for this!
September 5, 2025 at 2:32 PM
Our paper on VEL-dependent polymerization is featured on the cover of this month's issue of @cp-molcell.bsky.social 🎉 The cover art was created by my talented friend Awesta - the result of hours of brainstorming together over video. Great fun teaming up for this!
Reposted by Anna Schulten
NEWS - Professor Yiliang Ding awarded prestigious Royal Society Faraday Discovery Fellowship
These long-term @royalsociety.org awards are worth £8m over 10 years to support exceptional mid-career research leaders in the UK. Congratulations @yiliangding.bsky.social 👏
👉 www.jic.ac.uk/press-releas...
These long-term @royalsociety.org awards are worth £8m over 10 years to support exceptional mid-career research leaders in the UK. Congratulations @yiliangding.bsky.social 👏
👉 www.jic.ac.uk/press-releas...
August 28, 2025 at 3:05 PM
NEWS - Professor Yiliang Ding awarded prestigious Royal Society Faraday Discovery Fellowship
These long-term @royalsociety.org awards are worth £8m over 10 years to support exceptional mid-career research leaders in the UK. Congratulations @yiliangding.bsky.social 👏
👉 www.jic.ac.uk/press-releas...
These long-term @royalsociety.org awards are worth £8m over 10 years to support exceptional mid-career research leaders in the UK. Congratulations @yiliangding.bsky.social 👏
👉 www.jic.ac.uk/press-releas...
Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...
VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing
Schulten et al. show that VEL polymerization domains produce higher-order protein
assemblies to maintain chromatin association of Polycomb proteins, enabling a stable
epigenetic switch at the floral r...
www.cell.com
August 26, 2025 at 6:04 PM
Excited to share the paper from my work in the Dean lab @johninnescentre.bsky.social out now in @cp-molcell.bsky.social. Huge thanks to all the co-authors - it was a great collaborative effort! Watch out for the associated cover artwork coming out next week 🎉 www.cell.com/molecular-ce...
Reposted by Anna Schulten
The final version of our paper showing VRN2-PRC2 mediated control of PIF4 signalling is now published in the latest issue of Developmental Cell @cellpress.bsky.social. Many thanks to Zhe Wu for writing an accompanying Preview piece summarising the work, here: www.cell.com/developmenta...
PRC2-mediated repression of PIF4 targets beyond the on/off switch of gene expression
In this issue of Developmental Cell, Osborne et al. report that the angiosperm-specific
polycomb repressive complex 2 (PRC2) subunit VERNALIZATION 2 (VRN2) regulates leaf
growth by stable deposition o...
www.cell.com
August 5, 2025 at 8:25 AM
The final version of our paper showing VRN2-PRC2 mediated control of PIF4 signalling is now published in the latest issue of Developmental Cell @cellpress.bsky.social. Many thanks to Zhe Wu for writing an accompanying Preview piece summarising the work, here: www.cell.com/developmenta...
Reposted by Anna Schulten
The new issue of @newphyt.bsky.social features a profile of Caroline Dean:
👉 nph.onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #PlantEpigenetics #PlantLuminaries
👉 nph.onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #PlantEpigenetics #PlantLuminaries
August 1, 2025 at 9:56 AM
The new issue of @newphyt.bsky.social features a profile of Caroline Dean:
👉 nph.onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #PlantEpigenetics #PlantLuminaries
👉 nph.onlinelibrary.wiley.com/doi/10.1111/...
#PlantScience #PlantEpigenetics #PlantLuminaries
Reposted by Anna Schulten
Big congratulations to @kellythd-nguyen.bsky.social 👍👍👍Super beautiful structure👍👍👍Very happy to contribute some RNA structure work to this great collaboration😊 @johninnescentre.bsky.social @mrclmb.bsky.social
Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization
Telomerase ribonucleoprotein (RNP) synthesizes telomeric repeats at chromosome ends using a telomerase reverse transcriptase (TERT) and a telomerase RNA (hTR in humans). Previous structural work showe...
www.science.org
July 10, 2025 at 10:24 PM
Big congratulations to @kellythd-nguyen.bsky.social 👍👍👍Super beautiful structure👍👍👍Very happy to contribute some RNA structure work to this great collaboration😊 @johninnescentre.bsky.social @mrclmb.bsky.social
Reposted by Anna Schulten
Just dropping this here in case anyone is interested in joining 🙃
May 14, 2025 at 8:51 AM
Just dropping this here in case anyone is interested in joining 🙃
Reposted by Anna Schulten
Happy to see our latest paper by @drosborneplantsci.bsky.social et al out today in Developmental Cell @cellpress.bsky.social! We identify a role for VRN2-PRC2 in regulating light-responsive growth in Arabidopsis through the conditional epigenetic repression of PIF signalling. tinyurl.com/swbyff24
VRN2-PRC2 facilitates light-triggered repression of PIF signaling to coordinate growth in Arabidopsis
Osborne et al. show that the angiosperm-specific PRC2 subunit VRN2 is enriched in
hypoxic regions of the Arabidopsis shoot, where it is required for stable deposition
of H3K27me3 in key PIF4 target ge...
tinyurl.com
March 26, 2025 at 3:10 PM
Happy to see our latest paper by @drosborneplantsci.bsky.social et al out today in Developmental Cell @cellpress.bsky.social! We identify a role for VRN2-PRC2 in regulating light-responsive growth in Arabidopsis through the conditional epigenetic repression of PIF signalling. tinyurl.com/swbyff24
Reposted by Anna Schulten
Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates.
Thanks to all the authors and colleagues!
Thanks to all the authors and colleagues!
February 28, 2025 at 11:37 AM
Our paper has been published! We used in vivo single-particle tracking to demonstrate that the assembly of core FCA oligomers into functional macromolecular condensates.
Thanks to all the authors and colleagues!
Thanks to all the authors and colleagues!
Reposted by Anna Schulten
In vivo single-particle tracking by Geng-Jen Jang, Caroline Dean et al reveals the modular assembly of #Arabidopsis gene expression regulator FLOWERING CONTROL LOCUS A from oligomers into molecular condensates competent for RNA 3’-processing
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
February 24, 2025 at 2:47 PM
In vivo single-particle tracking by Geng-Jen Jang, Caroline Dean et al reveals the modular assembly of #Arabidopsis gene expression regulator FLOWERING CONTROL LOCUS A from oligomers into molecular condensates competent for RNA 3’-processing
www.embopress.org/doi/full/10....
www.embopress.org/doi/full/10....
Reposted by Anna Schulten
We are happy to share our work on local #nucleosome dynamics integrating #temperature inputs into an #epigenetic switching mechanism.
⚠️ Preprint alert!!
www.biorxiv.org/content/10.1...
⚠️ Preprint alert!!
www.biorxiv.org/content/10.1...
Cold-induced nucleosome dynamics linked to silencing of Arabidopsis FLC
Temperature influences nucleosome dynamics, and thus chromatin, to regulate gene expression. Such mechanisms underlie the epigenetic silencing of Arabidopsis FLOWERING LOCUS C (FLC) by prolonged cold....
www.biorxiv.org
February 21, 2025 at 2:06 PM
We are happy to share our work on local #nucleosome dynamics integrating #temperature inputs into an #epigenetic switching mechanism.
⚠️ Preprint alert!!
www.biorxiv.org/content/10.1...
⚠️ Preprint alert!!
www.biorxiv.org/content/10.1...
Reposted by Anna Schulten
I've written a commentary for Cell Systems arguing that biology needs to find a way to communicate its complexity from the outset, rather than starting with simple but misleading narratives.
It's free to view and download here (until 1 April).
authors.elsevier.com/a/1karS8YyDf...
It's free to view and download here (until 1 April).
authors.elsevier.com/a/1karS8YyDf...
authors.elsevier.com
February 11, 2025 at 3:52 PM
I've written a commentary for Cell Systems arguing that biology needs to find a way to communicate its complexity from the outset, rather than starting with simple but misleading narratives.
It's free to view and download here (until 1 April).
authors.elsevier.com/a/1karS8YyDf...
It's free to view and download here (until 1 April).
authors.elsevier.com/a/1karS8YyDf...