Pauline Franz
@paulinefranz.bsky.social
Chemical Biologist in 🇬🇧 ¦ passionate about illustrating science 🐡
#proteinchemistry
#proteinchemistry
Pinned
Pauline Franz
@paulinefranz.bsky.social
· Dec 19
What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!!
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
Reposted by Pauline Franz
I am very happy to share that I was awarded a PhD fellowship from the Boehringer Ingelheim Fonds (BIF) for my project about nucleosome depletion in @lcbm-epfl.bsky.social with @beatfierz.bsky.social. Looking forward to joining the BIF community 😊🥳
April 4, 2025 at 12:28 PM
I am very happy to share that I was awarded a PhD fellowship from the Boehringer Ingelheim Fonds (BIF) for my project about nucleosome depletion in @lcbm-epfl.bsky.social with @beatfierz.bsky.social. Looking forward to joining the BIF community 😊🥳
Reposted by Pauline Franz
#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates.
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky
February 4, 2025 at 1:13 PM
#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates.
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky
We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇
www.nature.com/articles/s41...
(1/8) #ChemBio #ChemSky
Reposted by Pauline Franz
Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup.
➡️Register now www.grc.org/histone-and-...
➡️Register now www.grc.org/histone-and-...
December 8, 2024 at 11:38 AM
Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup.
➡️Register now www.grc.org/histone-and-...
➡️Register now www.grc.org/histone-and-...
Reposted by Pauline Franz
Dear world: this is what a graphical abstract is supposed to look like.
What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!!
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
December 19, 2024 at 1:22 PM
Dear world: this is what a graphical abstract is supposed to look like.
What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!!
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
December 19, 2024 at 12:29 PM
What a great conclusion to my final days at EPFL: our 🔥article is highlighted on the @angewandtechemie.bsky.social Frontispiece!!
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
▶️ tinyurl.com/mvtecrsz
@beatfierz.bsky.social #chemicalbiology #clickchemistry #DNArepair #SciArt🐡 🧪
Reposted by Pauline Franz
Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!
December 10, 2024 at 1:54 PM
Hi there: we're happy to be on BlueSky now, too! Stay tuned as we're getting set up here for the #ChemSky community - more to follow soon!
Reposted by Pauline Franz
🥳 Today we celebrated the PhD defense of our very first PhD student Kevin Schiefelbein 🤩 Kevin told us about his Lasso Peptide journey over the past four years, and it was so great to see the full story coming together. Congratulations Kevin, and thank you for everything! #proudPI
December 4, 2024 at 8:45 PM
🥳 Today we celebrated the PhD defense of our very first PhD student Kevin Schiefelbein 🤩 Kevin told us about his Lasso Peptide journey over the past four years, and it was so great to see the full story coming together. Congratulations Kevin, and thank you for everything! #proudPI
Reposted by Pauline Franz
Reposted by Pauline Franz
We want to thank everyone for joining and to congratulate the winners! A big thank you to all sponsors supporting this meeting!
We hope to see you all next time.
#LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science
We hope to see you all next time.
#LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science
November 27, 2024 at 10:10 AM
We want to thank everyone for joining and to congratulate the winners! A big thank you to all sponsors supporting this meeting!
We hope to see you all next time.
#LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science
We hope to see you all next time.
#LS2 #ICMT #Biophysics #LifeScience #Switzerland #Conference #Science
Reposted by Pauline Franz
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 3, 2024 at 7:05 AM
Very excited to present the structural and mechanistic basis for stress response silencing by the monster E3 ligase SIFI.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Pauline Franz
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
December 2, 2024 at 12:10 PM
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
Reposted by Pauline Franz
Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
November 25, 2024 at 1:47 PM
Look who's here
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
@pnas.org ✔️
@science.org ✔️
@naturecellbiology.bsky.social ✔️
@natrevgenet.bsky.social ✔️
@naturebiotech.bsky.social ✔️
@naturemicrobiol.bsky.social ✔️
@naturechemistry.bsky.social ✔️
@genesdev.bsky.social ✔️
@cellchembiol.bsky.social ✔️
@genomeresearch.bsky.social ✔️
@jcellbiol.bsky.social ✔️
Reposted by Pauline Franz
MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall. www.nature.com/articles/s41...
Cephalopod-inspired jetting devices for gastrointestinal drug delivery - Nature
Tethered or ingestible delivery systems that deliver liquid microjets in axial and radial directions can be used to deliver macromolecules to different parts of the gastrointestinal tract with good bi...
www.nature.com
November 25, 2024 at 8:52 AM
MIT researchers in collaboration with Novo Nordisk report in Nature an alternative to injections for the delivery of biologic drugs. This needle-free method leverages an ingestible capsule inspired by squids that releases drugs directly into the digestive tract wall. www.nature.com/articles/s41...
Reposted by Pauline Franz
On November 20, the new class of peptide-cyanobenzene dye photocatalysts developed by Xingyu have been first made public in a preprint at ChemRxiv, including a great collaboration Wei Cai in the @beatfierz.bsky.social group and Dr. Anne Sophie Chauvin
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
November 23, 2024 at 8:29 AM
On November 20, the new class of peptide-cyanobenzene dye photocatalysts developed by Xingyu have been first made public in a preprint at ChemRxiv, including a great collaboration Wei Cai in the @beatfierz.bsky.social group and Dr. Anne Sophie Chauvin
chemrxiv.org/engage/chemr...
chemrxiv.org/engage/chemr...
Reposted by Pauline Franz
Celebrating #FluorescenceFriday and hopefully brightening your timeline with these live intestinal #organoids stained with our actin probe SPY555-FastAct.
November 22, 2024 at 8:40 AM
Celebrating #FluorescenceFriday and hopefully brightening your timeline with these live intestinal #organoids stained with our actin probe SPY555-FastAct.
Reposted by Pauline Franz
This the (short, funny, sad) video we got to see on imaging women's brains at the CZI Imaging meeting as part of Nina Miolane's talk. Worth a few minutes and worth a share. www.youtube.com/watch?v=tX5u...
November 19, 2024 at 3:32 PM
This the (short, funny, sad) video we got to see on imaging women's brains at the CZI Imaging meeting as part of Nina Miolane's talk. Worth a few minutes and worth a share. www.youtube.com/watch?v=tX5u...
Reposted by Pauline Franz
🚨 Attention #teamtomo PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here: roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
2025 Summer Intern - Department of Structural Biology
Department Summary The CryoEM Group in the Department of Structural Biology is dedicated to providing high-resolution structural insights into biological macromolecules involved in health and disease....
roche.wd3.myworkdayjobs.com
November 18, 2024 at 5:49 AM
🚨 Attention #teamtomo PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here: roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...
Reposted by Pauline Franz
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
docs.bsky.app
November 18, 2024 at 2:48 PM
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
Reposted by Pauline Franz
📯📯 Chemical Biology starter pack 📯📯
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
November 17, 2024 at 10:58 PM
📯📯 Chemical Biology starter pack 📯📯
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
140 PIs & groups posting primary research in chemical biology.
Please reskeet (?) & reply to this post if you want to be added!
go.bsky.app/KLrTWoj
Let's make ChemBioSky even greater again!
#realtimechem #FluorescenceFriday #chemsky #chemtwitter #AgentOrange
Reposted by Pauline Franz
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
November 17, 2024 at 6:48 PM
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
🔄Share to help people finding its topic/field
- STRUCTURAL BIOLOGY
Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
Reposted by Pauline Franz
Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn
November 15, 2024 at 7:38 PM
Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn
Reposted by Pauline Franz
I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know
November 14, 2024 at 8:48 AM
I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know
Reposted by Pauline Franz
More than 9000 studies published in open-access journals contain figures created using the commercial scientific illustration service BioRender, which should technically mean that they are available for free reuse. But that doesn’t appear to be the case.
www.chemistryworld.com/news/thousan...
www.chemistryworld.com/news/thousan...
Thousands of published studies may contain images with incorrect copyright licences
Questions raised over copyright licence that covers images created using scientific illustration service Biorender
www.chemistryworld.com
October 28, 2024 at 10:49 AM
More than 9000 studies published in open-access journals contain figures created using the commercial scientific illustration service BioRender, which should technically mean that they are available for free reuse. But that doesn’t appear to be the case.
www.chemistryworld.com/news/thousan...
www.chemistryworld.com/news/thousan...
Reposted by Pauline Franz
Here is a starter pack dedicated to fluorescent probes, sensors and fluorophores makers.
I'm sure it's incomplete, please reply to this post to be added or suggest someone.
go.bsky.app/MtgJE4w
I'm sure it's incomplete, please reply to this post to be added or suggest someone.
go.bsky.app/MtgJE4w
November 13, 2024 at 9:24 PM
Here is a starter pack dedicated to fluorescent probes, sensors and fluorophores makers.
I'm sure it's incomplete, please reply to this post to be added or suggest someone.
go.bsky.app/MtgJE4w
I'm sure it's incomplete, please reply to this post to be added or suggest someone.
go.bsky.app/MtgJE4w
Reposted by Pauline Franz
Great to see so many new people from the scientific community joining here. Welcome! I would be very happy to connect with everyone on topics such as #Science, #Chemistry, #Chemsky, #ChemicalBiology, #Antibiotics, #CovalentInhibitors, #ChemicalProteomics, #ABPP and general topics of #academia.
November 13, 2024 at 8:48 AM
Great to see so many new people from the scientific community joining here. Welcome! I would be very happy to connect with everyone on topics such as #Science, #Chemistry, #Chemsky, #ChemicalBiology, #Antibiotics, #CovalentInhibitors, #ChemicalProteomics, #ABPP and general topics of #academia.