Tim Triche, Jr.🔰
@timtriche.bsky.social
Chief panhandler, trichelab.vai.org
Posts may contain trace quantities of blood🩸, chromatin 🧬 & stats 🧮
https://scholar.google.com/citations?user=AOoIO74AAAAJ
Views expressed are my own (but for the right price they can be yours!)
Posts may contain trace quantities of blood🩸, chromatin 🧬 & stats 🧮
https://scholar.google.com/citations?user=AOoIO74AAAAJ
Views expressed are my own (but for the right price they can be yours!)
Pinned
Tim Triche, Jr.🔰
@timtriche.bsky.social
· Jan 23
NIH funded research benefits your community even if it doesn’t (yet!) directly benefit you. Each $ invested in NIH yields significantly higher return on investment (average 254%) than the same $ invested in “defense”.
Call your reps: (202) 224-3121
www.unitedformedicalresearch.org/nih-in-your-...
Call your reps: (202) 224-3121
www.unitedformedicalresearch.org/nih-in-your-...
Reposted by Tim Triche, Jr.🔰
The Senate may choose to vote together on the DHS and LHHS bills. Thus, a filibuster on DHS may mean no funding for NIH. What my colleagues are saying:
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
January 25, 2026 at 5:19 AM
The Senate may choose to vote together on the DHS and LHHS bills. Thus, a filibuster on DHS may mean no funding for NIH. What my colleagues are saying:
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
“Shut it down, public health will understand. I’ll work without pay again.”
- anonymous NIHer
Reposted by Tim Triche, Jr.🔰
woke all-pro offensive lineman
January 25, 2026 at 7:19 PM
woke all-pro offensive lineman
Reposted by Tim Triche, Jr.🔰
January 25, 2026 at 1:55 AM
Reposted by Tim Triche, Jr.🔰
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.
White. Hot. Rage.
White. Hot. Rage.
January 24, 2026 at 7:31 PM
Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.
White. Hot. Rage.
White. Hot. Rage.
Reposted by Tim Triche, Jr.🔰
Your written protocols and lab notebooks are a love letter to your future self (whether it’s you or a future lab member). Please be kind. Here are some critical things I have frequently noticed missing: (feel free to add yours in thread 🧵)
January 21, 2026 at 9:21 PM
Your written protocols and lab notebooks are a love letter to your future self (whether it’s you or a future lab member). Please be kind. Here are some critical things I have frequently noticed missing: (feel free to add yours in thread 🧵)
Reposted by Tim Triche, Jr.🔰
Applications for our summer internship program are open. This is a paid, 9 week experience designed to provide research experience to undergraduates interested in the neurosciences, especially as related to the molecular and cellular basis of neuropsychiatric disorders
www.libd.org/summer-inter...
www.libd.org/summer-inter...
Summer Internship
Summer internship
www.libd.org
January 21, 2026 at 1:54 PM
Applications for our summer internship program are open. This is a paid, 9 week experience designed to provide research experience to undergraduates interested in the neurosciences, especially as related to the molecular and cellular basis of neuropsychiatric disorders
www.libd.org/summer-inter...
www.libd.org/summer-inter...
Reposted by Tim Triche, Jr.🔰
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
HLi Lab - Vacancies
Openings
hlilab.github.io
January 14, 2026 at 3:44 PM
I am looking for a postdoc to develop high-performance algorithms in computational genomics. Email or DM me if interested. For more information, see hlilab.github.io/vacancies. RTs appreciated!
Reposted by Tim Triche, Jr.🔰
Ok, I got my own answer, use html coding to get formatting into your personal statement part: www.markdownguide.org/basic-syntax/
January 16, 2026 at 1:21 PM
Ok, I got my own answer, use html coding to get formatting into your personal statement part: www.markdownguide.org/basic-syntax/
Brianna Bribel's biology videos are amazing, you should follow her @bumblingbiochemist.bsky.social in 2026.
Since people are talking about resolutions, let’s talk about resolution! Resolution in protein (and other macromolecular) structures – a quick overview of what it is and why it matters
youtube.com/shorts/uKycb...
youtube.com/shorts/uKycb...
Resolution in protein (etc.) structures – a quick overview of what it is and why it matters
YouTube video by the bumbling biochemist
youtube.com
January 1, 2026 at 10:27 PM
Brianna Bribel's biology videos are amazing, you should follow her @bumblingbiochemist.bsky.social in 2026.
Works for me. I’ll make this my major objective in 2026
January 1, 2026 at 5:56 PM
Works for me. I’ll make this my major objective in 2026
The Uncanny Valley of biology: good for pulling in expensive program grants, largely useless for understanding life itself
The Virtual Cell is biologists' Golem, story-told with whatever the latest technology happens to be.
(PPIs, metabolic networks, ODEs, ChIP-Seq GRNs, LLMs, ...)
(PPIs, metabolic networks, ODEs, ChIP-Seq GRNs, LLMs, ...)
December 27, 2025 at 4:48 PM
The Uncanny Valley of biology: good for pulling in expensive program grants, largely useless for understanding life itself
Reposted by Tim Triche, Jr.🔰
Thanks to the AWS Open Data program, this dataset along some derived data is also openly accessible via @AWSCloud at openhgl.s3.us-east-1.amazonaws.com/index.html
December 22, 2025 at 5:01 PM
Thanks to the AWS Open Data program, this dataset along some derived data is also openly accessible via @AWSCloud at openhgl.s3.us-east-1.amazonaws.com/index.html
BCD, right on schedule. I don’t think we will regret sending our work to this fine journal. Great work @dblipka.bsky.social and @mphartmann.bsky.social … I didn’t have time to read the PDF but I’m assuming it evolved a bit during review? It was exciting even before😁
ONLINE FIRST ALERT!
Molecular #Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
aacrjournals.org/bloodcancerd...
@aacrjournals.bsky.social
#childhoodcancer
#epigenetics
#precisiononcology
Molecular #Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
aacrjournals.org/bloodcancerd...
@aacrjournals.bsky.social
#childhoodcancer
#epigenetics
#precisiononcology
December 6, 2025 at 1:12 PM
BCD, right on schedule. I don’t think we will regret sending our work to this fine journal. Great work @dblipka.bsky.social and @mphartmann.bsky.social … I didn’t have time to read the PDF but I’m assuming it evolved a bit during review? It was exciting even before😁
Reposted by Tim Triche, Jr.🔰
579 high-quality human genomes from @humanpangenome.bsky.social, Arab Pangenome and individual papers (CHM13, CN1, KSA001, I002C, YAO and KOREF1). Sequences available in the AGC format (3.7GB) and FM-index in the ropebwt3 format (20.3GB). For details, see github.com/lh3/human-asm
GitHub - lh3/human-asm: A collection of high-quality human genomes
A collection of high-quality human genomes. Contribute to lh3/human-asm development by creating an account on GitHub.
github.com
December 3, 2025 at 3:44 AM
579 high-quality human genomes from @humanpangenome.bsky.social, Arab Pangenome and individual papers (CHM13, CN1, KSA001, I002C, YAO and KOREF1). Sequences available in the AGC format (3.7GB) and FM-index in the ropebwt3 format (20.3GB). For details, see github.com/lh3/human-asm
Reposted by Tim Triche, Jr.🔰
Guaranteed funding for five years and a 20% increase in a $39K base stipend if you haul in a fellowship. World class facilities and faculty in metabolism, structural biology, epigenetics, and beyond. Grand Rapids is half the cost of living of California or Boston. Apply by December 1st if interested
October 22, 2025 at 3:55 PM
Guaranteed funding for five years and a 20% increase in a $39K base stipend if you haul in a fellowship. World class facilities and faculty in metabolism, structural biology, epigenetics, and beyond. Grand Rapids is half the cost of living of California or Boston. Apply by December 1st if interested
Reposted by Tim Triche, Jr.🔰
the reason why he’s doing this
November 29, 2025 at 2:23 PM
the reason why he’s doing this
Guaranteed funding for five years and a 20% increase in a $39K base stipend if you haul in a fellowship. World class facilities and faculty in metabolism, structural biology, epigenetics, and beyond. Grand Rapids is half the cost of living of California or Boston. Apply by December 1st if interested
October 22, 2025 at 3:55 PM
Guaranteed funding for five years and a 20% increase in a $39K base stipend if you haul in a fellowship. World class facilities and faculty in metabolism, structural biology, epigenetics, and beyond. Grand Rapids is half the cost of living of California or Boston. Apply by December 1st if interested
Reposted by Tim Triche, Jr.🔰
🦒Long read giraffe is out!🦒
Mapping long reads to pangenome graphs is ~10x faster than with GraphAligner, with veeery slightly better mapping accuracy, short variant calling, and SV genotyping than GraphAligner or Minimap2
Mapping long reads to pangenome graphs is ~10x faster than with GraphAligner, with veeery slightly better mapping accuracy, short variant calling, and SV genotyping than GraphAligner or Minimap2
Rapid, accurate long- and short-read mapping to large pangenome graphs with vg Giraffe https://www.biorxiv.org/content/10.1101/2025.09.29.678807v1
October 2, 2025 at 6:28 AM
🦒Long read giraffe is out!🦒
Mapping long reads to pangenome graphs is ~10x faster than with GraphAligner, with veeery slightly better mapping accuracy, short variant calling, and SV genotyping than GraphAligner or Minimap2
Mapping long reads to pangenome graphs is ~10x faster than with GraphAligner, with veeery slightly better mapping accuracy, short variant calling, and SV genotyping than GraphAligner or Minimap2
Reposted by Tim Triche, Jr.🔰
We want to congratulate our President, Dr. Tony Letai, on his appointment as Director of the NCI. This announcement marks an historic moment for cancer research. Dr. Letai has been a tireless advocate and visionary leader for functional precision medicine 🧵
www.nih.gov/news-events/...
www.nih.gov/news-events/...
Secretary Kennedy Swears in Dr. Anthony Letai as Director of the National Cancer Institute
Dr. Letai will serve as NCI’s 18th director.
www.nih.gov
September 29, 2025 at 10:00 PM
We want to congratulate our President, Dr. Tony Letai, on his appointment as Director of the NCI. This announcement marks an historic moment for cancer research. Dr. Letai has been a tireless advocate and visionary leader for functional precision medicine 🧵
www.nih.gov/news-events/...
www.nih.gov/news-events/...
Good news for @alice.soragnilab.com, SFPM, and rare disease models. Bad news for mouse cancer enthusiasts (humans are unreliable models of mouse disease).
Exclusive: Anthony Letai, a cancer researcher and oncologist at the Dana-Farber Cancer Institute and Harvard University, has emerged as a leading candidate to be the next director of the National Cancer Institute. www.statnews.com/2025/09/24/n...
Anthony Letai of Dana-Farber is front-runner to lead National Cancer Institute
A popular and respected scientist is reported to be in line to lead the nation's most important cancer research office.
www.statnews.com
September 24, 2025 at 10:37 PM
Good news for @alice.soragnilab.com, SFPM, and rare disease models. Bad news for mouse cancer enthusiasts (humans are unreliable models of mouse disease).
Reposted by Tim Triche, Jr.🔰
Reposted by Tim Triche, Jr.🔰
Mathematical models in biology are powerful, but often hard to run, visualise, or reuse without specialist skills.
Menelmacar is a new platform that makes biological models interactive and easy to explore directly in the browser: biomodels.bacpop.org
🧬💻
Menelmacar is a new platform that makes biological models interactive and easy to explore directly in the browser: biomodels.bacpop.org
🧬💻
September 8, 2025 at 10:25 AM
Mathematical models in biology are powerful, but often hard to run, visualise, or reuse without specialist skills.
Menelmacar is a new platform that makes biological models interactive and easy to explore directly in the browser: biomodels.bacpop.org
🧬💻
Menelmacar is a new platform that makes biological models interactive and easy to explore directly in the browser: biomodels.bacpop.org
🧬💻
Post a perfect album from the 90s that isn’t Nirvana, Pearl Jam, Soundgarden, or Alice In Chains
September 8, 2025 at 12:14 AM
Post a perfect album from the 90s that isn’t Nirvana, Pearl Jam, Soundgarden, or Alice In Chains
What gif pops up for your name?
August 15, 2025 at 1:07 AM
What gif pops up for your name?