Magnus Karlsson-Good
@mkgood.bsky.social
Clinical psychologist and doctoral student working to improve internet-based CBT. Interested in stats and open science. #ClinPsych #cbtworks
https://www.oru.se/english/employee/magnus_karlsson-good
https://www.oru.se/english/employee/magnus_karlsson-good
Reposted by Magnus Karlsson-Good
who says the humanities are dead
"You can get ChatGPT to help you build a nuclear bomb if you simply design the prompt in the form of a poem, according to a new study from researchers in Europe. "
www.wired.com/story/poems-...
www.wired.com/story/poems-...
Poems Can Trick AI Into Helping You Make a Nuclear Weapon
It turns out all the guardrails in the world won’t protect a chatbot from meter and rhyme.
www.wired.com
December 1, 2025 at 1:46 AM
who says the humanities are dead
Reposted by Magnus Karlsson-Good
1- Insomnia in older adults can be difficult to address. CBT-insomnia is the gold standard - and the safest intervention.
Yet low-dose quetiapine is being used more to treat insomnia. How safe is it?
The authors of this study sought to find out.
#medsky
link.springer.com/article/10.1...
Yet low-dose quetiapine is being used more to treat insomnia. How safe is it?
The authors of this study sought to find out.
#medsky
link.springer.com/article/10.1...
November 30, 2025 at 9:40 PM
1- Insomnia in older adults can be difficult to address. CBT-insomnia is the gold standard - and the safest intervention.
Yet low-dose quetiapine is being used more to treat insomnia. How safe is it?
The authors of this study sought to find out.
#medsky
link.springer.com/article/10.1...
Yet low-dose quetiapine is being used more to treat insomnia. How safe is it?
The authors of this study sought to find out.
#medsky
link.springer.com/article/10.1...
Reposted by Magnus Karlsson-Good
Patient-blaming rhetoric is baked into alternative medicine.
The idea is that if you could just...
“Change your mindset”
“Live naturally”
“Eliminate toxins” (with supplements)
“Resolve trauma”
...then you can avoid serious health conditions such as cancer.
The idea is that if you could just...
“Change your mindset”
“Live naturally”
“Eliminate toxins” (with supplements)
“Resolve trauma”
...then you can avoid serious health conditions such as cancer.
November 30, 2025 at 6:52 PM
Patient-blaming rhetoric is baked into alternative medicine.
The idea is that if you could just...
“Change your mindset”
“Live naturally”
“Eliminate toxins” (with supplements)
“Resolve trauma”
...then you can avoid serious health conditions such as cancer.
The idea is that if you could just...
“Change your mindset”
“Live naturally”
“Eliminate toxins” (with supplements)
“Resolve trauma”
...then you can avoid serious health conditions such as cancer.
Reposted by Magnus Karlsson-Good
Neurobabble from top to bottom. Neurotransmitters are where ‘wanting’ comes from, drawing conclusions about typical behaviour (laziness) from clinical cases (strokes), and brain scans while students who vary on some motivation scale decided if hypothetical apples are worth squeezing their hand
Does ‘laziness’ start in the brain?
Understanding the surprising mechanism behind apathy can help unlock scientific ways to boost your motivation
www.theguardian.com
November 30, 2025 at 12:56 PM
Neurobabble from top to bottom. Neurotransmitters are where ‘wanting’ comes from, drawing conclusions about typical behaviour (laziness) from clinical cases (strokes), and brain scans while students who vary on some motivation scale decided if hypothetical apples are worth squeezing their hand
Reposted by Magnus Karlsson-Good
🚨 Our team has just published a Registered Report in BMC Medicine, one of the very few medical journals that offers this format (if we want better science, we should not follow journal impact factors, we should support journals with the best policies).
Efficacy and safety of esketamine for “treatment resistant depression”: registered report for a systematic review with an individual patient data meta-analysis of randomized, double-blind, placebo-con...
Background In 2019, the FDA and EMA approved intranasal esketamine for treatment-resistant depression (TRD). The current study re-evaluated its efficacy and safety. Methods This registered report pres...
link.springer.com
November 29, 2025 at 1:06 PM
🚨 Our team has just published a Registered Report in BMC Medicine, one of the very few medical journals that offers this format (if we want better science, we should not follow journal impact factors, we should support journals with the best policies).
Reposted by Magnus Karlsson-Good
I maintain that once somebody published a study, anybody can criticize it publicly, & there is no *obligation* to wait for the original authors' (OA) to reply.
1st, why would the OAs get to have the last word at every step?
2nd, waiting opens up a loophole for the OAs to derail the process.
1st, why would the OAs get to have the last word at every step?
2nd, waiting opens up a loophole for the OAs to derail the process.
November 30, 2025 at 5:38 AM
I maintain that once somebody published a study, anybody can criticize it publicly, & there is no *obligation* to wait for the original authors' (OA) to reply.
1st, why would the OAs get to have the last word at every step?
2nd, waiting opens up a loophole for the OAs to derail the process.
1st, why would the OAs get to have the last word at every step?
2nd, waiting opens up a loophole for the OAs to derail the process.
Reposted by Magnus Karlsson-Good
A thread of directed acyclic graphs (DAGs) that look like record covers... because that's EXACTLY what the world needs
1. Huey Lewis and the News: link.springer.com/chapter/10.1...
1. Huey Lewis and the News: link.springer.com/chapter/10.1...
November 28, 2025 at 11:36 AM
A thread of directed acyclic graphs (DAGs) that look like record covers... because that's EXACTLY what the world needs
1. Huey Lewis and the News: link.springer.com/chapter/10.1...
1. Huey Lewis and the News: link.springer.com/chapter/10.1...
Reposted by Magnus Karlsson-Good
Imagine posing for a photographer friend who sells your image to iStock and a year later, you see this is what The Washington Post has done with the image of you walking on a beautiful fall day
November 29, 2025 at 6:02 AM
Imagine posing for a photographer friend who sells your image to iStock and a year later, you see this is what The Washington Post has done with the image of you walking on a beautiful fall day
Reposted by Magnus Karlsson-Good
My hot take is that in the era of easily-generated AI nonsense papers journals that want to ensure high quality will need to start hiring full-time professional editors and reviewers instead of relying on volunteer labor from overworked academics.
UPDATE: The publisher intends to retract the paper, but insists it went through two rounds of review from two independent peer reviewers: nobreakthroughs.substack.com/p/riding-the... by @jacksonwryan.com. No word on how they will make sure this sort of thing never happens again.
Riding the Autism Bicycle to Retraction Town
Does anyone *really* know their Factor Fexcectorn?
nobreakthroughs.substack.com
November 28, 2025 at 3:23 PM
My hot take is that in the era of easily-generated AI nonsense papers journals that want to ensure high quality will need to start hiring full-time professional editors and reviewers instead of relying on volunteer labor from overworked academics.
Reposted by Magnus Karlsson-Good
Out now in Translational Psychiatry! www.nature.com/articles/s41...
November 28, 2025 at 2:53 PM
Out now in Translational Psychiatry! www.nature.com/articles/s41...
Reposted by Magnus Karlsson-Good
"Runctitiononal features"? "Medical fymblal"? "1 Tol Line storee"? This gets worse the longer you look at it. But it's got to be good, because it was published in Nature Scientific Reports last week: www.nature.com/articles/s41... h/t @asa.tsbalans.se
November 27, 2025 at 9:30 AM
"Runctitiononal features"? "Medical fymblal"? "1 Tol Line storee"? This gets worse the longer you look at it. But it's got to be good, because it was published in Nature Scientific Reports last week: www.nature.com/articles/s41... h/t @asa.tsbalans.se
Reposted by Magnus Karlsson-Good
How do I get people to understand that high quality data collected with intention and analyzed by experts have even more potential to revolutionize health care?
Can't even make jokes anymore because Deloitte did use AI to say that AI is good...
www.ctvnews.ca/canada/newfo...
www.ctvnews.ca/canada/newfo...
November 27, 2025 at 7:11 AM
How do I get people to understand that high quality data collected with intention and analyzed by experts have even more potential to revolutionize health care?
Reposted by Magnus Karlsson-Good
Reposted by Magnus Karlsson-Good
In the first seven days since I launched this new game, almost ten thousand people from 82 countries have played it. (Top cities so far: New York City, Zurich, Toronto, Chicago, Berlin, Vienna, Stockholm)
What topics would you like me to add next?
dataguessr.com
What topics would you like me to add next?
dataguessr.com
Dataguessr
Update your knowledge of the world. One quiz at a time.
dataguessr.com
September 19, 2025 at 3:17 PM
In the first seven days since I launched this new game, almost ten thousand people from 82 countries have played it. (Top cities so far: New York City, Zurich, Toronto, Chicago, Berlin, Vienna, Stockholm)
What topics would you like me to add next?
dataguessr.com
What topics would you like me to add next?
dataguessr.com
Reposted by Magnus Karlsson-Good
Imagine you lived in the 18th century.
Smallpox kills 1 in 3 cases. Yet you can’t culture pathogens, don’t know germ theory, and have no idea what a virus is. How would you invent a vaccine?
In a new episode of HARD DRUGS, we trace the history of vaccines!
Smallpox kills 1 in 3 cases. Yet you can’t culture pathogens, don’t know germ theory, and have no idea what a virus is. How would you invent a vaccine?
In a new episode of HARD DRUGS, we trace the history of vaccines!
The history of vaccines
open.spotify.com
November 26, 2025 at 5:16 PM
Imagine you lived in the 18th century.
Smallpox kills 1 in 3 cases. Yet you can’t culture pathogens, don’t know germ theory, and have no idea what a virus is. How would you invent a vaccine?
In a new episode of HARD DRUGS, we trace the history of vaccines!
Smallpox kills 1 in 3 cases. Yet you can’t culture pathogens, don’t know germ theory, and have no idea what a virus is. How would you invent a vaccine?
In a new episode of HARD DRUGS, we trace the history of vaccines!
Reposted by Magnus Karlsson-Good
Handing back student work that’s been written by ChatGPT with a 0 followed by the comment “This essay will never stand in authentic wonder before the Beauty of God’s creation.”
Pope Leo XIV told students not to use artificial intelligence for homework, saying that AI ‘won’t stand in authentic wonder before the beauty of God’s creation.’
Even God Is Worried About ChatGPT
Pope Leo XIV told students not to use artificial intelligence for homework, saying that AI ‘won’t stand in authentic wonder before the beauty of God’s creation.’
www.vulture.com
November 26, 2025 at 3:35 PM
Handing back student work that’s been written by ChatGPT with a 0 followed by the comment “This essay will never stand in authentic wonder before the Beauty of God’s creation.”
Reposted by Magnus Karlsson-Good
Problems with the so-called gender equality paradox
statmodeling.stat.columbia.edu/2025/11/25/p...
statmodeling.stat.columbia.edu/2025/11/25/p...
Problems with the so-called gender equality paradox | Statistical Modeling, Causal Inference, and Social Science
statmodeling.stat.columbia.edu
November 25, 2025 at 2:53 PM
Problems with the so-called gender equality paradox
statmodeling.stat.columbia.edu/2025/11/25/p...
statmodeling.stat.columbia.edu/2025/11/25/p...
Reposted by Magnus Karlsson-Good
this is one of my favourite observations about sample size calculations. (afaik first articulated by Miettinen in 1985)
November 25, 2025 at 10:56 AM
this is one of my favourite observations about sample size calculations. (afaik first articulated by Miettinen in 1985)
Reposted by Magnus Karlsson-Good
There is no reason why systematic reviews can't be open. The data used for synthesis is *already* open and there are many excellent open source tools that can facilitate the easy sharing of analysis scripts.
Here's a nice guide for performing open systematic reviews doi.org/10.1525/coll...
Here's a nice guide for performing open systematic reviews doi.org/10.1525/coll...
November 24, 2025 at 12:10 PM
There is no reason why systematic reviews can't be open. The data used for synthesis is *already* open and there are many excellent open source tools that can facilitate the easy sharing of analysis scripts.
Here's a nice guide for performing open systematic reviews doi.org/10.1525/coll...
Here's a nice guide for performing open systematic reviews doi.org/10.1525/coll...
Reposted by Magnus Karlsson-Good
A friend who teaches theology shared with me a post about CS Lewis's Mere Christianity, which discusses foundational Christian logic across denominations. It reminded me of Dale's tweet below, and I wanted to share some thoughts here regarding modesty and respectability, which are often hot topics.
November 23, 2025 at 7:35 PM
A friend who teaches theology shared with me a post about CS Lewis's Mere Christianity, which discusses foundational Christian logic across denominations. It reminded me of Dale's tweet below, and I wanted to share some thoughts here regarding modesty and respectability, which are often hot topics.
Reposted by Magnus Karlsson-Good
Sasha Gusev declares case closed by comparing studies that assessed different traits using different measurement methods in different countries at different times with different estimands for heritability, ignoring the denominator (total variance).
Academics who disagree are "overly cautious"
Academics who disagree are "overly cautious"
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 23, 2025 at 2:01 PM
Sasha Gusev declares case closed by comparing studies that assessed different traits using different measurement methods in different countries at different times with different estimands for heritability, ignoring the denominator (total variance).
Academics who disagree are "overly cautious"
Academics who disagree are "overly cautious"
Reposted by Magnus Karlsson-Good
Believe in growth mindset? Alex Burgoyne’s talk at #psynom25 might change your mind. Their meta-analysis found that growth mindset interventions did not predict academic achievement once publication bias and study quality were accounted for. 1/
November 22, 2025 at 10:18 PM
Believe in growth mindset? Alex Burgoyne’s talk at #psynom25 might change your mind. Their meta-analysis found that growth mindset interventions did not predict academic achievement once publication bias and study quality were accounted for. 1/
Reposted by Magnus Karlsson-Good
The trauma and grief these women experienced—having a stillborn baby or losing the baby after birth means you still produce breastmilk. You still have 10 mo of hormonal changes that will not disappear overnight. To have this pain trivialized & erased is truly filthy.
Accountability is required
Accountability is required
Influencers made millions pushing ‘wild’ births – now the Free Birth Society is linked to baby deaths around the world
Influencers made millions pushing ‘wild’ births – now the Free Birth Society is linked to baby deaths around the world
A year-long investigation reveals how mothers lost children after being radicalised by uplifting podcast tales of births without midwives or doctors
As Esau Lopez was asphyxiated for the first 17 minutes of his life on Earth, the atmosphere in the room remained serene, even ecstatic. Acoustic music crooned from a speaker in a modest two-bedroom apartment in a suburb of Pennsylvania. “You are a queen,” murmured one of three friends in the room.
Only Esau’s mother, Gabrielle Lopez, felt something was wrong. She was pushing hard, but her son would not be born. “Can you help [him] out?” she asked, as Esau crowned. “Baby is coming,” the friend replied. Four minutes later, Lopez asked again, “Can you grab [him]?” Another friend murmured, “Baby is safe.” Six minutes passed. Again, Lopez asked, “Can you grab [him]?” Continue reading...
www.theguardian.com
November 23, 2025 at 6:18 AM
The trauma and grief these women experienced—having a stillborn baby or losing the baby after birth means you still produce breastmilk. You still have 10 mo of hormonal changes that will not disappear overnight. To have this pain trivialized & erased is truly filthy.
Accountability is required
Accountability is required
Reposted by Magnus Karlsson-Good
This from @davidbatherwoods.bsky.social's biography of Schopenhauer is sending me
November 17, 2025 at 9:15 PM
This from @davidbatherwoods.bsky.social's biography of Schopenhauer is sending me
Reposted by Magnus Karlsson-Good
"Academic accommodations for anxiety convey two harmful messages. First, they imply that the feared situation is truly dangerous. Public speaking, testing, or lunch with classmates are too risky...Second, they suggest that the student can’t withstand the distress. Those messages increase anxiety."
Schools Are Accommodating Student Anxiety — and Making It Worse
Removing stressors robs students of growth opportunities, writes TC's Ben Lovett and his co-author Alex Jordan
www.tc.columbia.edu
November 21, 2025 at 4:42 PM
"Academic accommodations for anxiety convey two harmful messages. First, they imply that the feared situation is truly dangerous. Public speaking, testing, or lunch with classmates are too risky...Second, they suggest that the student can’t withstand the distress. Those messages increase anxiety."