Florian Naudet
@floriannaudet.bsky.social
Meta-researcher, Clinician, Professor at Rennes University, Senior member at Institut Universitaire de France, affiliate at METRICStanford. ORCID: 0000-0003-3760-3801
Posts are my own.
Website: https://restores.univ-rennes.fr/
Posts are my own.
Website: https://restores.univ-rennes.fr/
Pinned
Florian Naudet
@floriannaudet.bsky.social
· Nov 24
It is good to see the move on Bluesky because, X was starting to be boring. Nice to e-meet so many new followers here. Here is a 🧶 that is introduces most of my research interests. It is about #metaresearch #openscience and #medicine.
Reposted by Florian Naudet
A week after @bmj.com published a highly publicized paper claiming stem cell therapy can reduce the risk of heart failure, sleuths have unearthed what they are calling “serious” inconsistencies in the data.
Sleuths flag ‘complete mismatch’ in data of BMJ stem cell study
A week after The BMJ published a highly publicized paper claiming stem cell therapy can reduce the risk of heart failure, sleuths have unearthed what they are calling “serious” inconsistencies in t…
retractionwatch.com
November 6, 2025 at 10:59 PM
A week after @bmj.com published a highly publicized paper claiming stem cell therapy can reduce the risk of heart failure, sleuths have unearthed what they are calling “serious” inconsistencies in the data.
Reposted by Florian Naudet
There’s still time to register for the Friends of #NLM webinar
#AI / #LLMs and the Medical Journal: Threats and Opportunities Wed Nov 12, 2025 | 1– 3P Eastern
www.fnlm.org/product/arti... !
with PRC10 Co-Directors #AnnetteFlanagin #JohnIoannidis and
@chaug.bsky.social @gdtl.bsky.social and more!
#AI / #LLMs and the Medical Journal: Threats and Opportunities Wed Nov 12, 2025 | 1– 3P Eastern
www.fnlm.org/product/arti... !
with PRC10 Co-Directors #AnnetteFlanagin #JohnIoannidis and
@chaug.bsky.social @gdtl.bsky.social and more!
Artificial Intelligence, Including Large Language Models and the Medical Journal: Threats and Opportunities - Friends of the National Library of Medicine
www.fnlm.org
November 6, 2025 at 10:12 PM
There’s still time to register for the Friends of #NLM webinar
#AI / #LLMs and the Medical Journal: Threats and Opportunities Wed Nov 12, 2025 | 1– 3P Eastern
www.fnlm.org/product/arti... !
with PRC10 Co-Directors #AnnetteFlanagin #JohnIoannidis and
@chaug.bsky.social @gdtl.bsky.social and more!
#AI / #LLMs and the Medical Journal: Threats and Opportunities Wed Nov 12, 2025 | 1– 3P Eastern
www.fnlm.org/product/arti... !
with PRC10 Co-Directors #AnnetteFlanagin #JohnIoannidis and
@chaug.bsky.social @gdtl.bsky.social and more!
Reposted by Florian Naudet
Reposted by Florian Naudet
New JAMA Psychiatry report on clinical trial of ketamine vs midazolam (aka. Versed, a short-acting benzo mainly used as an anesthetic). No difference in efficacy found. High rates of AEs in both gps.
@floriannaudet.bsky.social @chrisaikenmd.bsky.social
watermark02.silverchair.com/jamapsychiat...
@floriannaudet.bsky.social @chrisaikenmd.bsky.social
watermark02.silverchair.com/jamapsychiat...
November 2, 2025 at 7:01 PM
New JAMA Psychiatry report on clinical trial of ketamine vs midazolam (aka. Versed, a short-acting benzo mainly used as an anesthetic). No difference in efficacy found. High rates of AEs in both gps.
@floriannaudet.bsky.social @chrisaikenmd.bsky.social
watermark02.silverchair.com/jamapsychiat...
@floriannaudet.bsky.social @chrisaikenmd.bsky.social
watermark02.silverchair.com/jamapsychiat...
🚨🎄 The Xmaths Webinar with Prof. Richard Riley (R²) 🎄🚨
12 Dec, 12:30... "Many physician–researchers think they’re stats experts… while statisticians wisely avoid improvising as physicians.”
Join R² for a deep dive into the art & science of statistics: pitfalls, errors, and how to avoid them.
12 Dec, 12:30... "Many physician–researchers think they’re stats experts… while statisticians wisely avoid improvising as physicians.”
Join R² for a deep dive into the art & science of statistics: pitfalls, errors, and how to avoid them.
On the 12th Day of Christmas, a Statistician Sent to Me…
Richard Riley (Department of Applied Health Sciences, University of Birmingham)
restores.univ-rennes.fr
October 24, 2025 at 11:21 AM
🚨🎄 The Xmaths Webinar with Prof. Richard Riley (R²) 🎄🚨
12 Dec, 12:30... "Many physician–researchers think they’re stats experts… while statisticians wisely avoid improvising as physicians.”
Join R² for a deep dive into the art & science of statistics: pitfalls, errors, and how to avoid them.
12 Dec, 12:30... "Many physician–researchers think they’re stats experts… while statisticians wisely avoid improvising as physicians.”
Join R² for a deep dive into the art & science of statistics: pitfalls, errors, and how to avoid them.
Hi @metricstanford.bsky.social welcome! You have been added to the meta-research / open science starting pack 2.
go.bsky.app/DWo6RbA
go.bsky.app/DWo6RbA
October 24, 2025 at 5:25 AM
Hi @metricstanford.bsky.social welcome! You have been added to the meta-research / open science starting pack 2.
go.bsky.app/DWo6RbA
go.bsky.app/DWo6RbA
Reposted by Florian Naudet
No significant effect for ketamine (vs midazolam) in this trial. This contrasts previous research. Functional unblinding and reduced expectancy effects due to the enrolment algorithm likely explain this finding (implying that older research is biased).
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Serial Ketamine Infusions for Depression
This randomized clinical trial evaluates outcomes following adjunctive ketamine infusions vs midazolam for depression.
jamanetwork.com
October 22, 2025 at 6:45 PM
No significant effect for ketamine (vs midazolam) in this trial. This contrasts previous research. Functional unblinding and reduced expectancy effects due to the enrolment algorithm likely explain this finding (implying that older research is biased).
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Florian Naudet
👉Also Sorbonne bsky.app/profile/sorb... pulled out of 'THE' University Ranking 👇
Important step in times of massive, systematic gaming by Universities, being a main incentive for Hyperprolific Publishing, Citation Cartels, Paper Mills & Junk Science!
#researchintegrity, #Chemsky, #CompChemSky
Important step in times of massive, systematic gaming by Universities, being a main incentive for Hyperprolific Publishing, Citation Cartels, Paper Mills & Junk Science!
#researchintegrity, #Chemsky, #CompChemSky
Why Sorbonne pulled out of university ranking
France’s Sorbonne University plans to leave the Times Higher Education (THE) Rankings, adding its name to a growing number of universities rejecting lists that play one institution off against another...
sciencebusiness.net
October 19, 2025 at 5:50 AM
👉Also Sorbonne bsky.app/profile/sorb... pulled out of 'THE' University Ranking 👇
Important step in times of massive, systematic gaming by Universities, being a main incentive for Hyperprolific Publishing, Citation Cartels, Paper Mills & Junk Science!
#researchintegrity, #Chemsky, #CompChemSky
Important step in times of massive, systematic gaming by Universities, being a main incentive for Hyperprolific Publishing, Citation Cartels, Paper Mills & Junk Science!
#researchintegrity, #Chemsky, #CompChemSky
Reposted by Florian Naudet
Happy to joint hands with you all!🙌
October 18, 2025 at 7:55 PM
Happy to joint hands with you all!🙌
Reposted by Florian Naudet
Great job @kahin-tai.bsky.social . Thanks for leading.
October 17, 2025 at 7:38 PM
Great job @kahin-tai.bsky.social . Thanks for leading.
😃 to share this new @plos.org Medicine 📄 written in collaboration with the super cool @kahin-tai.bsky.social (from the super cool @sharectd.bsky.social doctoral network), Gérard Legoff, @annelelouarn.bsky.social & @synthymama.bsky.social.
Open science must include effective results dissemination to study participants
Open science often centers around publications and data transparency. This Perspective discusses how and why disseminating results to study participants is essential for maximizing the values and bene...
journals.plos.org
October 16, 2025 at 9:08 AM
😃 to share this new @plos.org Medicine 📄 written in collaboration with the super cool @kahin-tai.bsky.social (from the super cool @sharectd.bsky.social doctoral network), Gérard Legoff, @annelelouarn.bsky.social & @synthymama.bsky.social.
Reposted by Florian Naudet
Hehe, rejection record so far: 5
🙈
🙈
October 5, 2025 at 9:07 AM
Hehe, rejection record so far: 5
🙈
🙈
New post on ResToRes's website: "The Lancet–WCRIF commission on research integrity"
A new Lancet–WCRIF Commission on Research Integrity takes aim at the growing crisis of fake science and questionable research practices, calling for coordinated global action.
restores.univ-rennes.fr/highlights/l...
A new Lancet–WCRIF Commission on Research Integrity takes aim at the growing crisis of fake science and questionable research practices, calling for coordinated global action.
restores.univ-rennes.fr/highlights/l...
October 5, 2025 at 7:52 AM
New post on ResToRes's website: "The Lancet–WCRIF commission on research integrity"
A new Lancet–WCRIF Commission on Research Integrity takes aim at the growing crisis of fake science and questionable research practices, calling for coordinated global action.
restores.univ-rennes.fr/highlights/l...
A new Lancet–WCRIF Commission on Research Integrity takes aim at the growing crisis of fake science and questionable research practices, calling for coordinated global action.
restores.univ-rennes.fr/highlights/l...
Reposted by Florian Naudet
Our reflections from #Metascience25 are now up in our blog, incl. what we learned about #OpenScience from national frameworks, the Metascience Alliance, an IPCC-like proposal and what comes next for evidence-based Open Science policy.
Read more 👉 www.grios.org/grios-at-met...
#Metascience #Research
Read more 👉 www.grios.org/grios-at-met...
#Metascience #Research
October 1, 2025 at 3:08 PM
Our reflections from #Metascience25 are now up in our blog, incl. what we learned about #OpenScience from national frameworks, the Metascience Alliance, an IPCC-like proposal and what comes next for evidence-based Open Science policy.
Read more 👉 www.grios.org/grios-at-met...
#Metascience #Research
Read more 👉 www.grios.org/grios-at-met...
#Metascience #Research
Reposted by Florian Naudet
Science is grounded in observation. Measurement is a tool for observation. Measurements should be evaluated for validity and reliability/uncertainty. Scientists who use measurements without understanding their properties are not really scientists at all.
Can large language models stand in for human participants?
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
Many social scientists seem to think so, and are already using "silicon samples" in research.
One problem: depending on the analytic decisions made, you can basically get these samples to show any effect you want.
THREAD 🧵
The threat of analytic flexibility in using large language models to simulate human data: A call to attention
Social scientists are now using large language models to create "silicon samples" - synthetic datasets intended to stand in for human respondents, aimed at revolutionising human subjects research. How...
arxiv.org
October 1, 2025 at 5:39 AM
Science is grounded in observation. Measurement is a tool for observation. Measurements should be evaluated for validity and reliability/uncertainty. Scientists who use measurements without understanding their properties are not really scientists at all.
Reposted by Florian Naudet
A must read work from our network. 👍
"A New Hope: SHARE-CTD trilogy concludes with data reuse"
The @sharectd.bsky.social project concludes its "trilogy" with a guide to clinical trial data reuse. In this chapter, @giulia-varvar.bsky.social introduces principles to support effective data reuse.
restores.univ-rennes.fr/highlights/n...
The @sharectd.bsky.social project concludes its "trilogy" with a guide to clinical trial data reuse. In this chapter, @giulia-varvar.bsky.social introduces principles to support effective data reuse.
restores.univ-rennes.fr/highlights/n...
September 30, 2025 at 2:04 PM
A must read work from our network. 👍
Thanks to Adrien Fillon & Nathanael Larigaldie for inviting me on their podcast Répare ta science [In French] 🎙
ResToRes ta science -Florian Naudet # 14
open.spotify.com
September 30, 2025 at 12:44 PM
Thanks to Adrien Fillon & Nathanael Larigaldie for inviting me on their podcast Répare ta science [In French] 🎙
Reposted by Florian Naudet
Merci à toi d’être venu et j’espère que tu apprécie le titre, j’ai tout donné 😂
September 30, 2025 at 9:50 AM
Merci à toi d’être venu et j’espère que tu apprécie le titre, j’ai tout donné 😂
Reposted by Florian Naudet
ResToRes ta science, nouvel épisode dans lequel on a eu le plaisir d'interviewer @floriannaudet.bsky.social,
À retrouver ici :
À retrouver ici :
Répare Ta Science • A podcast on Spotify for Creators
Adrien Fillon et Nathanaël Larigaldie, deux chercheurs en psychologie, discutent les avancées de la méta-science et comment les méthodes scientifiques peuvent aider à réparer la science. Une fois par mois.
podcasters.spotify.com
September 30, 2025 at 6:58 AM
ResToRes ta science, nouvel épisode dans lequel on a eu le plaisir d'interviewer @floriannaudet.bsky.social,
À retrouver ici :
À retrouver ici :
New post on ResToRes' website: Open science and transparency are the strongest tools we have to defend against fraudulent publishing. A @plos.org Medicine editorial argues that making data openly available protects the integrity of science.
restores.univ-rennes.fr/highlights/f...
restores.univ-rennes.fr/highlights/f...
September 29, 2025 at 8:31 PM
New post on ResToRes' website: Open science and transparency are the strongest tools we have to defend against fraudulent publishing. A @plos.org Medicine editorial argues that making data openly available protects the integrity of science.
restores.univ-rennes.fr/highlights/f...
restores.univ-rennes.fr/highlights/f...
New post on RestoRes's website. "New initiative seeks evidence for effective open science practices"
The Global Research Initiative on Open Science, officially launched last week, aims to identify what works (and what doesn’t) in Open Science worldwide.
restores.univ-rennes.fr/highlights/n...
The Global Research Initiative on Open Science, officially launched last week, aims to identify what works (and what doesn’t) in Open Science worldwide.
restores.univ-rennes.fr/highlights/n...
September 28, 2025 at 7:47 AM
New post on RestoRes's website. "New initiative seeks evidence for effective open science practices"
The Global Research Initiative on Open Science, officially launched last week, aims to identify what works (and what doesn’t) in Open Science worldwide.
restores.univ-rennes.fr/highlights/n...
The Global Research Initiative on Open Science, officially launched last week, aims to identify what works (and what doesn’t) in Open Science worldwide.
restores.univ-rennes.fr/highlights/n...
Reposted by Florian Naudet
I'm pleased to say that the paper I have written with the amazing guide of @floriannaudet.bsky.social and is now online.
The trilogy is finally concluded!
The trilogy is finally concluded!
"A New Hope: SHARE-CTD trilogy concludes with data reuse"
The @sharectd.bsky.social project concludes its "trilogy" with a guide to clinical trial data reuse. In this chapter, @giulia-varvar.bsky.social introduces principles to support effective data reuse.
restores.univ-rennes.fr/highlights/n...
The @sharectd.bsky.social project concludes its "trilogy" with a guide to clinical trial data reuse. In this chapter, @giulia-varvar.bsky.social introduces principles to support effective data reuse.
restores.univ-rennes.fr/highlights/n...
September 26, 2025 at 1:13 PM
I'm pleased to say that the paper I have written with the amazing guide of @floriannaudet.bsky.social and is now online.
The trilogy is finally concluded!
The trilogy is finally concluded!
👇👇👇
1/32 Fluoxetine's loss of efficacy for the treatment of pediatric depression.
🚨 New paper and pre-print alert 🚨
With great colleagues @floriannaudet.bsky.social @richlyus.bsky.social @markhoro.bsky.social @joannamoncrieff.bsky.social and Gert van Valkenhoef
A longer 🧵
🚨 New paper and pre-print alert 🚨
With great colleagues @floriannaudet.bsky.social @richlyus.bsky.social @markhoro.bsky.social @joannamoncrieff.bsky.social and Gert van Valkenhoef
A longer 🧵
September 26, 2025 at 5:20 AM
👇👇👇
Reposted by Florian Naudet
32/ “...Overall, resolving these challenges goes beyond the scope of our commentary and we hope that it will stir necessary discussions, re-evaluations of guidelines, and treatment recommendations.”
Our preprint is here and it has now been accepted for publication: osf.io/preprints/ps...
Our preprint is here and it has now been accepted for publication: osf.io/preprints/ps...
OSF
osf.io
September 26, 2025 at 5:00 AM
32/ “...Overall, resolving these challenges goes beyond the scope of our commentary and we hope that it will stir necessary discussions, re-evaluations of guidelines, and treatment recommendations.”
Our preprint is here and it has now been accepted for publication: osf.io/preprints/ps...
Our preprint is here and it has now been accepted for publication: osf.io/preprints/ps...