Florian Naudet
@floriannaudet.bsky.social
Meta-researcher, Clinician, Professor at Rennes University, Senior member at Institut Universitaire de France, affiliate at METRICStanford. ORCID: 0000-0003-3760-3801
Posts are my own.
Website: https://restores.univ-rennes.fr/
Posts are my own.
Website: https://restores.univ-rennes.fr/
Pinned
Esketamine for depression, registered reports, and alcohol use disorder | Metascience Matters #2
YouTube video by Metascience Matters
www.youtube.com
Super happy to be interviewed by Randy Ellis for his Metascience Matters podcast 🎙️
Really fun and open discussion. Less about meta-science in the narrow sense, and more about science as it’s actually practiced, plus the everyday realities of academic life.
Thanks Randy for the great conversation!
Really fun and open discussion. Less about meta-science in the narrow sense, and more about science as it’s actually practiced, plus the everyday realities of academic life.
Thanks Randy for the great conversation!
Reposted by Florian Naudet
Direction of effect and success of publcation: a randomized study has really been done already!
Thanks to @floriannaudet.bsky.social for pointing it out
jamanetwork.com/journals/jam...
Thanks to @floriannaudet.bsky.social for pointing it out
jamanetwork.com/journals/jam...
February 10, 2026 at 8:48 PM
Direction of effect and success of publcation: a randomized study has really been done already!
Thanks to @floriannaudet.bsky.social for pointing it out
jamanetwork.com/journals/jam...
Thanks to @floriannaudet.bsky.social for pointing it out
jamanetwork.com/journals/jam...
Reposted by Florian Naudet
Well worth tuning in to!
Another talk on how a single small Zombie-trial biased the results for fluoxetine in influential Lancet meta-analyses. This time for the University of Cambridge.
With @richlyus.bsky.social and @floriannaudet.bsky.social
Time: 26 February, 12:30-13:30 (UK), via Zoom
talks.cam.ac.uk/talk/index/2...
With @richlyus.bsky.social and @floriannaudet.bsky.social
Time: 26 February, 12:30-13:30 (UK), via Zoom
talks.cam.ac.uk/talk/index/2...
talks.cam.ac.uk
February 8, 2026 at 4:31 PM
Well worth tuning in to!
Reposted by Florian Naudet
Another talk on how a single small Zombie-trial biased the results for fluoxetine in influential Lancet meta-analyses. This time for the University of Cambridge.
With @richlyus.bsky.social and @floriannaudet.bsky.social
Time: 26 February, 12:30-13:30 (UK), via Zoom
talks.cam.ac.uk/talk/index/2...
With @richlyus.bsky.social and @floriannaudet.bsky.social
Time: 26 February, 12:30-13:30 (UK), via Zoom
talks.cam.ac.uk/talk/index/2...
talks.cam.ac.uk
February 8, 2026 at 3:03 PM
Another talk on how a single small Zombie-trial biased the results for fluoxetine in influential Lancet meta-analyses. This time for the University of Cambridge.
With @richlyus.bsky.social and @floriannaudet.bsky.social
Time: 26 February, 12:30-13:30 (UK), via Zoom
talks.cam.ac.uk/talk/index/2...
With @richlyus.bsky.social and @floriannaudet.bsky.social
Time: 26 February, 12:30-13:30 (UK), via Zoom
talks.cam.ac.uk/talk/index/2...
Reposted by Florian Naudet
February 5, 2026 at 12:40 PM
Reposted by Florian Naudet
Basic questions like "how many participants are in the dataset?" can produce surprisingly different answers between analysts.
Results from students in my class in data wrangling in tidyverse, who are good at wrangling but still have to make semi-subjective choices:
Results from students in my class in data wrangling in tidyverse, who are good at wrangling but still have to make semi-subjective choices:
February 5, 2026 at 12:40 PM
Basic questions like "how many participants are in the dataset?" can produce surprisingly different answers between analysts.
Results from students in my class in data wrangling in tidyverse, who are good at wrangling but still have to make semi-subjective choices:
Results from students in my class in data wrangling in tidyverse, who are good at wrangling but still have to make semi-subjective choices:
🚨🚨 Important thread 🙂
Heading to Utrecht ✈️ to kick off one of the most data-intensive and stimulating projects I’m involved in: the 2nd @sharectd.bsky.social Datathon.
Heading to Utrecht ✈️ to kick off one of the most data-intensive and stimulating projects I’m involved in: the 2nd @sharectd.bsky.social Datathon.
February 8, 2026 at 9:18 AM
🚨🚨 Important thread 🙂
Heading to Utrecht ✈️ to kick off one of the most data-intensive and stimulating projects I’m involved in: the 2nd @sharectd.bsky.social Datathon.
Heading to Utrecht ✈️ to kick off one of the most data-intensive and stimulating projects I’m involved in: the 2nd @sharectd.bsky.social Datathon.
👋 all,
The LORIER Ambassador webinar series continues next Friday (February, the 13) at 12:30 (Paris time) with a talk by Constant Vinatier from the OSIRIS Consortium.
In case you are interested, DM me and I'll send you the link.
"Open Science Practices in Biomedical Journals"
The LORIER Ambassador webinar series continues next Friday (February, the 13) at 12:30 (Paris time) with a talk by Constant Vinatier from the OSIRIS Consortium.
In case you are interested, DM me and I'll send you the link.
"Open Science Practices in Biomedical Journals"
February 6, 2026 at 8:43 AM
👋 all,
The LORIER Ambassador webinar series continues next Friday (February, the 13) at 12:30 (Paris time) with a talk by Constant Vinatier from the OSIRIS Consortium.
In case you are interested, DM me and I'll send you the link.
"Open Science Practices in Biomedical Journals"
The LORIER Ambassador webinar series continues next Friday (February, the 13) at 12:30 (Paris time) with a talk by Constant Vinatier from the OSIRIS Consortium.
In case you are interested, DM me and I'll send you the link.
"Open Science Practices in Biomedical Journals"
Reposted by Florian Naudet
1. Our response to a review by Le et al. on optimal dosing of ketamine, which was based on efficacy studies and neuroplasticity research, just came out (with @floriannaudet.bsky.social).
The review is here: www.sciencedirect.com/science/arti...
The review is here: www.sciencedirect.com/science/arti...
Recommendations for repeated dosings of ketamine/esketamine rest on an uncertain evidence base. Response to
www.sciencedirect.com
February 5, 2026 at 8:58 AM
1. Our response to a review by Le et al. on optimal dosing of ketamine, which was based on efficacy studies and neuroplasticity research, just came out (with @floriannaudet.bsky.social).
The review is here: www.sciencedirect.com/science/arti...
The review is here: www.sciencedirect.com/science/arti...
Reposted by Florian Naudet
"Would be" 😉
Their nondisclosure is also evidence
Their nondisclosure is also evidence
January 30, 2026 at 8:59 PM
"Would be" 😉
Their nondisclosure is also evidence
Their nondisclosure is also evidence
Reposted by Florian Naudet
Bonjour @artefr.bsky.social, @28minutes-arte.bsky.social.
Voici un tweet récent.
Un compte Twitter à plus de 38'000 abonnés.
Ce qu'ils diffusent là, c'est de la #désinformation pure sur une question de #santé grave.
De la désinformation que vous avez fabriquée, sous couvert de #journalisme
1/11
Voici un tweet récent.
Un compte Twitter à plus de 38'000 abonnés.
Ce qu'ils diffusent là, c'est de la #désinformation pure sur une question de #santé grave.
De la désinformation que vous avez fabriquée, sous couvert de #journalisme
1/11
January 30, 2026 at 6:45 PM
Bonjour @artefr.bsky.social, @28minutes-arte.bsky.social.
Voici un tweet récent.
Un compte Twitter à plus de 38'000 abonnés.
Ce qu'ils diffusent là, c'est de la #désinformation pure sur une question de #santé grave.
De la désinformation que vous avez fabriquée, sous couvert de #journalisme
1/11
Voici un tweet récent.
Un compte Twitter à plus de 38'000 abonnés.
Ce qu'ils diffusent là, c'est de la #désinformation pure sur une question de #santé grave.
De la désinformation que vous avez fabriquée, sous couvert de #journalisme
1/11
Reposted by Florian Naudet
Good response!
They did not declare any COIs. Do they really have no COI?
From what I understand, these expert centers allow academic career.
They did not declare any COIs. Do they really have no COI?
From what I understand, these expert centers allow academic career.
January 30, 2026 at 6:06 PM
Good response!
They did not declare any COIs. Do they really have no COI?
From what I understand, these expert centers allow academic career.
They did not declare any COIs. Do they really have no COI?
From what I understand, these expert centers allow academic career.
Last year, we published an article analyzing the advocacy activities of the FondaMental Foundation around its “expert centers.” We documented repeated claims of a 50% reduction in hospitalizations, echoed in exchanges with members of parliament and incorporated into a draft law.
Advocacy by nonprofit scientific institutions needs to be evidence-based: a case study
Scientific institutions, including universities and research centers, occasionally engage in advocacy to gain financial support. However, this can be …
www.sciencedirect.com
January 29, 2026 at 9:16 PM
Last year, we published an article analyzing the advocacy activities of the FondaMental Foundation around its “expert centers.” We documented repeated claims of a 50% reduction in hospitalizations, echoed in exchanges with members of parliament and incorporated into a draft law.
Reposted by Florian Naudet
www.bmj.com/content/392/... by Ilona Kickbusch.
Europe has greater responsibility in the WHO without the United States
The US’s withdrawal from WHO makes Europe the system stabiliser in global health multilateralism, writes Ilona Kickbusch
At the upcoming executive board meeting of the World Health Organization (WHO...
www.bmj.com
January 28, 2026 at 4:39 PM
www.bmj.com/content/392/... by Ilona Kickbusch.
Reposted by Florian Naudet
Problems summarized here, with links to the preprint and the INSPECT-SR checklist
pubpeer.com/publications...
pubpeer.com/publications...
January 26, 2026 at 3:18 PM
Problems summarized here, with links to the preprint and the INSPECT-SR checklist
pubpeer.com/publications...
pubpeer.com/publications...
Reposted by Florian Naudet
Excellent talk of yours, and super interesting talks in general!
January 25, 2026 at 12:51 PM
Excellent talk of yours, and super interesting talks in general!
Reposted by Florian Naudet
Perhaps an article of interest from our team: J Clin Epidemiol, 2022 vol. 150 pp. 90-97
Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines.
www.ncbi.nlm.nih.gov/pubmed/35779...
Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines.
www.ncbi.nlm.nih.gov/pubmed/35779...
January 25, 2026 at 11:43 AM
Perhaps an article of interest from our team: J Clin Epidemiol, 2022 vol. 150 pp. 90-97
Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines.
www.ncbi.nlm.nih.gov/pubmed/35779...
Retracted randomized controlled trials were cited and not corrected in systematic reviews and clinical practice guidelines.
www.ncbi.nlm.nih.gov/pubmed/35779...
🎥 The NASEM panel “Systematic Reviews and Corrections and Retractions” is now featured on RestoRes website.
With L Bero and J Wilkinson we discussed how corrections and retractions can impact the reliability of evidence syntheses.
restores.univ-rennes.fr/highlights/n...
With L Bero and J Wilkinson we discussed how corrections and retractions can impact the reliability of evidence syntheses.
restores.univ-rennes.fr/highlights/n...
January 25, 2026 at 6:56 AM
🎥 The NASEM panel “Systematic Reviews and Corrections and Retractions” is now featured on RestoRes website.
With L Bero and J Wilkinson we discussed how corrections and retractions can impact the reliability of evidence syntheses.
restores.univ-rennes.fr/highlights/n...
With L Bero and J Wilkinson we discussed how corrections and retractions can impact the reliability of evidence syntheses.
restores.univ-rennes.fr/highlights/n...
Reposted by Florian Naudet
n 13% of special issues produced by several major publishers in the past decade, guest editors contributed > 1/3 of the papers themselves, according to an @arxiv.bsky.social preprint
Article: arxiv.org/abs/2601.07563
News: science.org/content/arti...
@jeffreybrainard.bsky.social @science.org
Article: arxiv.org/abs/2601.07563
News: science.org/content/arti...
@jeffreybrainard.bsky.social @science.org
The Issue with Special Issues: when Guest Editors Publish in Support of Self
The recent exceptional growth in the number of special issues has led to the largest delegation of editorial power in the history of scientific publishing. Has this power been used responsibly? In thi...
arxiv.org
January 23, 2026 at 3:23 PM
n 13% of special issues produced by several major publishers in the past decade, guest editors contributed > 1/3 of the papers themselves, according to an @arxiv.bsky.social preprint
Article: arxiv.org/abs/2601.07563
News: science.org/content/arti...
@jeffreybrainard.bsky.social @science.org
Article: arxiv.org/abs/2601.07563
News: science.org/content/arti...
@jeffreybrainard.bsky.social @science.org
Reposted by Florian Naudet
I started a podcast! Metascience Matters features conversations with metascientists.
Two episodes are live:
Chirag Patel on Exposomics, and Vibration of Effects: youtu.be/RT2nypyb-iM?...
@floriannaudet.bsky.social on Clinical Trials, Registered Reports, and Psychiatry: youtu.be/fn4qtnc99Xo?...
Two episodes are live:
Chirag Patel on Exposomics, and Vibration of Effects: youtu.be/RT2nypyb-iM?...
@floriannaudet.bsky.social on Clinical Trials, Registered Reports, and Psychiatry: youtu.be/fn4qtnc99Xo?...
Exposomics, Vibration-of-Effects, and the Future of AI in Health | Metascience Matters #1
YouTube video by Metascience Matters
youtu.be
January 23, 2026 at 12:49 PM
I started a podcast! Metascience Matters features conversations with metascientists.
Two episodes are live:
Chirag Patel on Exposomics, and Vibration of Effects: youtu.be/RT2nypyb-iM?...
@floriannaudet.bsky.social on Clinical Trials, Registered Reports, and Psychiatry: youtu.be/fn4qtnc99Xo?...
Two episodes are live:
Chirag Patel on Exposomics, and Vibration of Effects: youtu.be/RT2nypyb-iM?...
@floriannaudet.bsky.social on Clinical Trials, Registered Reports, and Psychiatry: youtu.be/fn4qtnc99Xo?...
Super happy to be interviewed by Randy Ellis for his Metascience Matters podcast 🎙️
Really fun and open discussion. Less about meta-science in the narrow sense, and more about science as it’s actually practiced, plus the everyday realities of academic life.
Thanks Randy for the great conversation!
Really fun and open discussion. Less about meta-science in the narrow sense, and more about science as it’s actually practiced, plus the everyday realities of academic life.
Thanks Randy for the great conversation!
Esketamine for depression, registered reports, and alcohol use disorder | Metascience Matters #2
YouTube video by Metascience Matters
www.youtube.com
January 23, 2026 at 8:00 AM
Super happy to be interviewed by Randy Ellis for his Metascience Matters podcast 🎙️
Really fun and open discussion. Less about meta-science in the narrow sense, and more about science as it’s actually practiced, plus the everyday realities of academic life.
Thanks Randy for the great conversation!
Really fun and open discussion. Less about meta-science in the narrow sense, and more about science as it’s actually practiced, plus the everyday realities of academic life.
Thanks Randy for the great conversation!
Reposted by Florian Naudet
Services like RegCheck are extremely promising for moving norms forward from doing open science practices to doing open science practices well.
Comparing registrations to published papers is essential to research integrity - and almost no one does it routinely because it's slow, messy, and time-demanding.
RegCheck was built to help make this process easier.
Today, we launch RegCheck V2.
🧵
regcheck.app
RegCheck was built to help make this process easier.
Today, we launch RegCheck V2.
🧵
regcheck.app
RegCheck
RegCheck is an AI tool to compare preregistrations with papers instantly.
regcheck.app
January 22, 2026 at 12:50 PM
Services like RegCheck are extremely promising for moving norms forward from doing open science practices to doing open science practices well.
Reposted by Florian Naudet
Finally, the evidence I needed to show my kids that, "Yes, you did this to me!"
January 22, 2026 at 5:54 AM
Finally, the evidence I needed to show my kids that, "Yes, you did this to me!"
Reposted by Florian Naudet
Finally, after some exchange with the editors who requested the raw data (revealing more oddities), the paper was retracted.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
January 19, 2026 at 7:31 PM
Reposted by Florian Naudet
2. Same journal, RCT comparing meds with meds+tDCS
link.springer.com/article/10.1...
What do you think about the outcomes for depression at day 10 (end of treatment) and 3 months follow-up?
The follow-up results are too good to be true IMO.
The medication-only posttest SD seems erroneous.
link.springer.com/article/10.1...
What do you think about the outcomes for depression at day 10 (end of treatment) and 3 months follow-up?
The follow-up results are too good to be true IMO.
The medication-only posttest SD seems erroneous.
February 23, 2025 at 8:33 PM
2. Same journal, RCT comparing meds with meds+tDCS
link.springer.com/article/10.1...
What do you think about the outcomes for depression at day 10 (end of treatment) and 3 months follow-up?
The follow-up results are too good to be true IMO.
The medication-only posttest SD seems erroneous.
link.springer.com/article/10.1...
What do you think about the outcomes for depression at day 10 (end of treatment) and 3 months follow-up?
The follow-up results are too good to be true IMO.
The medication-only posttest SD seems erroneous.
Reposted by Florian Naudet
1. I now summarized problems of a paper on ketamine on PubPeer and also contacted the editor after contacting the author who didn't respond.
I also checked some other papers from authors and indeed found another suspicious one quickly. Thoughts? ->
pubpeer.com/publications...
I also checked some other papers from authors and indeed found another suspicious one quickly. Thoughts? ->
pubpeer.com/publications...
February 23, 2025 at 8:33 PM
1. I now summarized problems of a paper on ketamine on PubPeer and also contacted the editor after contacting the author who didn't respond.
I also checked some other papers from authors and indeed found another suspicious one quickly. Thoughts? ->
pubpeer.com/publications...
I also checked some other papers from authors and indeed found another suspicious one quickly. Thoughts? ->
pubpeer.com/publications...