Akansha Ganguly
@akanshaganguly.bsky.social
PhD student in Kalika Prasad's group, IISER Pune. Always found with chai and random debates. Interested in understanding morphogenesis, regeneration, and other existential questions
https://thelabofregeneration.in/Kalika_Prasad/index.html
https://thelabofregeneration.in/Kalika_Prasad/index.html
Reposted by Akansha Ganguly
Out in @science.org this week:
PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division.
www.science.org/doi/10.1126/...
#PlantScience
#PlantSci
PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division.
www.science.org/doi/10.1126/...
#PlantScience
#PlantSci
Cell wall patterning regulates plant stem cell dynamics
The plant cell wall regulates development through spatiotemporal modulation of its chemical and mechanical properties. Pectin methylesterification is recognized as a rheological switch controlling wal...
www.science.org
December 5, 2025 at 1:11 PM
Out in @science.org this week:
PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division.
www.science.org/doi/10.1126/...
#PlantScience
#PlantSci
PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division.
www.science.org/doi/10.1126/...
#PlantScience
#PlantSci
Reposted by Akansha Ganguly
Well this 2,600-year-old clay letter was a journey.
It comes from the archive of a goldsmith named Nabû-zeru-iddin in the heart of ancient Assyria. We’ve got someone left on read, a lawsuit, a mean step-mom, and people who get drunk and steal silver.
It comes from the archive of a goldsmith named Nabû-zeru-iddin in the heart of ancient Assyria. We’ve got someone left on read, a lawsuit, a mean step-mom, and people who get drunk and steal silver.
November 21, 2025 at 9:16 AM
Well this 2,600-year-old clay letter was a journey.
It comes from the archive of a goldsmith named Nabû-zeru-iddin in the heart of ancient Assyria. We’ve got someone left on read, a lawsuit, a mean step-mom, and people who get drunk and steal silver.
It comes from the archive of a goldsmith named Nabû-zeru-iddin in the heart of ancient Assyria. We’ve got someone left on read, a lawsuit, a mean step-mom, and people who get drunk and steal silver.
Reposted by Akansha Ganguly
Finally, Ondrej developed a very cool genetic cell-ablation tool based on tissue-specific induction of the murine pro-apoptotic factor mBax. It’s extremely useful when your confocal laser can’t reach internal tissues for laser ablation. 5/6
November 14, 2025 at 10:02 AM
Finally, Ondrej developed a very cool genetic cell-ablation tool based on tissue-specific induction of the murine pro-apoptotic factor mBax. It’s extremely useful when your confocal laser can’t reach internal tissues for laser ablation. 5/6
Reposted by Akansha Ganguly
Very nice work from @apmahonen.bsky.social
lab.. when vascular cambial stem cells are lost, neighbouring xylem cells, divide to replace them Auxin transport drive this remarkable positioning of stem cells in vascular cambium during development and regeneration.
www.pnas.org/doi/abs/10.1...
lab.. when vascular cambial stem cells are lost, neighbouring xylem cells, divide to replace them Auxin transport drive this remarkable positioning of stem cells in vascular cambium during development and regeneration.
www.pnas.org/doi/abs/10.1...
November 14, 2025 at 8:00 AM
Very nice work from @apmahonen.bsky.social
lab.. when vascular cambial stem cells are lost, neighbouring xylem cells, divide to replace them Auxin transport drive this remarkable positioning of stem cells in vascular cambium during development and regeneration.
www.pnas.org/doi/abs/10.1...
lab.. when vascular cambial stem cells are lost, neighbouring xylem cells, divide to replace them Auxin transport drive this remarkable positioning of stem cells in vascular cambium during development and regeneration.
www.pnas.org/doi/abs/10.1...
Reposted by Akansha Ganguly
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Induction of menstruation in mice reveals the regulation of menstrual shedding
During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...
www.biorxiv.org
October 10, 2025 at 12:50 PM
I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵
Reposted by Akansha Ganguly
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
October 5, 2025 at 10:35 AM
Latest from ours: www.cell.com/cell-reports...
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵
Reposted by Akansha Ganguly
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
October 14, 2025 at 10:56 AM
I found these immune cells just finished mitosis but their midbody is still yet to be resolved. How cool? If you zoom in to the midbody, you can see its classical shape just like in the textbooks. I love these little details.
Reposted by Akansha Ganguly
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
October 8, 2025 at 1:05 PM
New preprint from the lab! We discovered a transient fluidization in the basal region of human forebrains by tracking microdroplets in cerebral organoids.This “basal fluidization”, absent in gorilla and mouse, may contribute to greater surface expansion in human forebrains
1/
doi.org/10.1101/2025...
1/
doi.org/10.1101/2025...
Reposted by Akansha Ganguly
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
October 4, 2025 at 11:50 AM
I’m happy to share some plugins I’ve been developping this summer: "Channels and Contrast" and LUTs Manager!
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
I can’t find new bugs and ideas by now so I need your help to please test them in your machines and report bugs, feedbacks and ideas! forum.image.sc/t/looking-fo...
Reposted by Akansha Ganguly
A long road to the Cover of Science!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Localized glutamine leakage drives the spatial structure of root microbial colonization
Plant roots release exudates to encourage microbiome assembly, which influences the function and stress resilience of plants. How specific exudates drive spatial colonization patterns remains largely ...
www.science.org
October 3, 2025 at 12:45 PM
A long road to the Cover of Science!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Akansha Ganguly
Humbled to be a part of Indian Science Academies, @ IAScBng, @nasi_academy, and Now @insa_academy
Such moments remind me how fortunate I am to work with talented lab members (past and present), collaborators, colleagues and mentors all along. Thank you for this opportunity 🙏
Such moments remind me how fortunate I am to work with talented lab members (past and present), collaborators, colleagues and mentors all along. Thank you for this opportunity 🙏
September 29, 2025 at 8:39 AM
Humbled to be a part of Indian Science Academies, @ IAScBng, @nasi_academy, and Now @insa_academy
Such moments remind me how fortunate I am to work with talented lab members (past and present), collaborators, colleagues and mentors all along. Thank you for this opportunity 🙏
Such moments remind me how fortunate I am to work with talented lab members (past and present), collaborators, colleagues and mentors all along. Thank you for this opportunity 🙏
Reposted by Akansha Ganguly
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
October 3, 2025 at 9:06 AM
My entry for today’s #FluorescenceFriday: a pupal #Drosophila testis with muscles expressing
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
🔵 lifeact &
🔴 RFP-nls
Honored & grateful to receive an honorable mention at @healthcare.nikon.com Nikon Small World 🌍🔬✨
🔗 www.nikonsmallworld.com/galleries/20...
#NikonSmallWorld #Microscopy #ScienceArt
Reposted by Akansha Ganguly
New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
Bioelectricity in Morphogenesis
Bioelectricity is likely as old as life itself. From the moment the first proto-cell was enclosed in a lipid bilayer, a membrane potential arose. Thus, one can expect that bioelectrical activities inf...
www.annualreviews.org
October 2, 2025 at 8:14 PM
New Review! #devbiol #bioelectricity #CellBiology #tissueregeneration
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
In our new @annualreviews.bsky.social piece, we explore how bioelectricity is generated, sensed & translated into responses that sculpt tissues, guide growth & enable tissue regeneration.
www.annualreviews.org/content/jour...
Reposted by Akansha Ganguly
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
September 17, 2025 at 5:38 PM
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
Reposted by Akansha Ganguly
For #FluorescenceFriday, microtubule networks are shown in two adipocytes 🔬 #CellBiology #Microscopy
September 5, 2025 at 6:39 PM
For #FluorescenceFriday, microtubule networks are shown in two adipocytes 🔬 #CellBiology #Microscopy
Reposted by Akansha Ganguly
📣 It is my pleasure to announce our recent review with Margherita on the current approaches, challenges, and perspectives in studying human maternal-fetal interface using in vitro models www.cell.com/cell-stem-ce... 🚀✨️
September 5, 2025 at 9:07 AM
📣 It is my pleasure to announce our recent review with Margherita on the current approaches, challenges, and perspectives in studying human maternal-fetal interface using in vitro models www.cell.com/cell-stem-ce... 🚀✨️
Reposted by Akansha Ganguly
Wirshing, Lew et al. @mit.edu address how mothers partition growth equally among their buds in the multi-budding yeast Aureobasidium pullulans. Equal partitioning stems directly from effective equalization of #polarity sites. rupress.org/jcb/article/...
#Cytoskeleton #Development
#Cytoskeleton #Development
September 2, 2025 at 4:15 PM
Wirshing, Lew et al. @mit.edu address how mothers partition growth equally among their buds in the multi-budding yeast Aureobasidium pullulans. Equal partitioning stems directly from effective equalization of #polarity sites. rupress.org/jcb/article/...
#Cytoskeleton #Development
#Cytoskeleton #Development
Reposted by Akansha Ganguly
OIL ON THE 10X OBJECTIVE TEN THOUSAND YEARS DUNGEON
September 1, 2025 at 9:21 PM
OIL ON THE 10X OBJECTIVE TEN THOUSAND YEARS DUNGEON
Reposted by Akansha Ganguly
😺 to see this one out @jcellsci.bsky.social & have a 🌲 planted for it): journals.biologists.com/jcs/article/... am sure more creative people will make better use of this resource 1/2
September 1, 2025 at 5:26 AM
😺 to see this one out @jcellsci.bsky.social & have a 🌲 planted for it): journals.biologists.com/jcs/article/... am sure more creative people will make better use of this resource 1/2
Reposted by Akansha Ganguly
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
September 1, 2025 at 12:29 PM
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
Guest Editors: Alex Hughes and Rashmi Priya
📅 Deadline: 1 March 2026
journals.biologists.com/dev/pages/ex...
#DevBio
Reposted by Akansha Ganguly
Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation https://www.biorxiv.org/content/10.1101/2025.08.26.672295v1
August 30, 2025 at 1:16 PM
Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation https://www.biorxiv.org/content/10.1101/2025.08.26.672295v1
Reposted by Akansha Ganguly
Nice cell division observed on Zeiss LLS7 yesterday! Sample: @romainguiet.bsky.social
August 29, 2025 at 8:14 AM
Nice cell division observed on Zeiss LLS7 yesterday! Sample: @romainguiet.bsky.social
Reposted by Akansha Ganguly
New study led by Joanna Baker shows bigger brains and relatively longer thumbs coevolved in primates. Humans have huge thumbs, but only what our brain size (esp. neocortex) would predict. It’s NOT driven by tool use.
A fantastic paper with a huge amount of work, and superb data presentation 🧪🏺👍🧠💀🐒🦧
A fantastic paper with a huge amount of work, and superb data presentation 🧪🏺👍🧠💀🐒🦧
Human dexterity and brains evolved hand in hand - Communications Biology
Thumbs and brains coevolved in primates. Across living and extinct species, longer thumbs predict bigger brains, highlighting the neural cost of dexterity.
www.nature.com
August 26, 2025 at 10:01 AM
New study led by Joanna Baker shows bigger brains and relatively longer thumbs coevolved in primates. Humans have huge thumbs, but only what our brain size (esp. neocortex) would predict. It’s NOT driven by tool use.
A fantastic paper with a huge amount of work, and superb data presentation 🧪🏺👍🧠💀🐒🦧
A fantastic paper with a huge amount of work, and superb data presentation 🧪🏺👍🧠💀🐒🦧
Reposted by Akansha Ganguly
🌱✂️ How do plant cells decide where to divide?
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org
August 25, 2025 at 8:34 AM
🌱✂️ How do plant cells decide where to divide?
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
Our work shows that actin can override the geometric rules—guiding cells to divide in alternative orientations.
#PlantScience #CellBiology #Arabidopsis
@camilagoldy.bsky.social @rdplab.bsky.social
www.biorxiv.org/content/10.1...
Reposted by Akansha Ganguly
Scientists present an advanced new technique for live-imaging regenerating limbs, shown here on a sand flea.
buff.ly/WsOrSlR
buff.ly/WsOrSlR
August 25, 2025 at 10:44 AM
Scientists present an advanced new technique for live-imaging regenerating limbs, shown here on a sand flea.
buff.ly/WsOrSlR
buff.ly/WsOrSlR