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Development
@dev-journal.bsky.social
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Development is a leading research journal in the field of developmental biology, covering stem cells, regeneration, evo-devo, epigenetics, morphogenesis and more. @biologists.bsky.social
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Development @dev-journal.bsky.social · 25d
Our first issue of Vol 153 (2026) is complete!

On the cover: 3D image of the apical Drosophila pupal eye with depth-coding applied, showing a dome-like ommatidia.

See the Research Article by Bhattarai ( @abhibhattarai.bsky.social) et al. from @ruthjohnsonlab.bsky.social

doi.org/10.1242/dev....
3D image of the apical Drosophila pupal eye with depth-coding applied and a pronounced dome-like appearance of ommatidia, owing to the highly organized network of apical rib-like actin filaments (ARAFs)
dev-journal.bsky.social
Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells

Guest Editors: Alex Hughes (@hugheslabpenn.bsky.social) & Rashmi Priya (@rashmi-priya.bsky.social)

Deadline: 1 March 2026

journals.biologists.com/dev/pages/ex...
Special Issue The Extracellular Environment in Development, Regeneration and Stem Cells Guest Editors Alex Hughes (University of Pennsylvania) Rashmi Priya (The Francis Crick Institute) Submission deadline: 1 March 2026. Development call for papers. Image of magenta and teal cells in a jawbone.
February 10, 2026 at 4:24 PM
Reposted by Development
bardinlab.bsky.social
Very last chance to join us (Deadline tomorrow Feb 10!) at this Developmental Biology meeting!
Have a nice story? Come and discuss it with editors from @embojournal.org @plosbiology.org and @dev-journal.bsky.social !
A one hour info session from @erc.europa.eu will also be presented!
bardinlab.bsky.social Bardin Lab @bardinlab.bsky.social · Dec 3
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en
February 9, 2026 at 4:00 PM
dev-journal.bsky.social
To learn more about this paper and the people behind It, we spoke to Nikola Makdissi and Daria Hirschmann, co-first authors of the study from the Developmental Biology of the Immune System, Life & Medical Sciences (LIMES) Institute, Germany.

doi.org/10.1242/dev....
Co-first authors Nikola Makdissi (left) and Daria Hirschmann (right)
February 2, 2026 at 2:58 PM
dev-journal.bsky.social
Read the #OpenAccess Research Article ‘Kupffer cells control neonatal hepatic metabolism via Igf1 signaling’ here:

doi.org/10.1242/dev....
February 2, 2026 at 2:58 PM
dev-journal.bsky.social
Inadequate imposters: Kupffer cells influence liver metabolism

This Research Highlight showcases work by Nikola Makdissi, Daria J. Hirschmann, Elvira Mass (@masslab.bsky.social) and colleagues

journals.biologists.com/dev/article/...
Figure 3 - KOSpi1 hepatocytes contain less glycogen storage at birth. (A) Representative PAS (purple)-Hematoxylin (H, blue) staining of WTSpi1 and KOSpi1 livers at P0. Scale bars: 200 µm. (B) Scheme indicating how PAS staining intensity was quantified using Fiji. (C) Normalized PAS signal intensity of WTSpi1 and KOSpi1 livers at P0. Circles represent individual mice. n=3-4 per genotype from 2 independent litters. Paired Student's t-test. Data are shown as mean±s.d. (D) Glycogen levels measured on whole liver lysates of WTSpi1 and KOSpi1 P0 livers. n=5 per genotype from 3 independent litters. Values were normalized per litter. The whiskers represent the 5-95% percentile, the box extends from the 25th to 75th percentiles and the horizontal line represents the median. Cross indicates the mean. Mann–Whitney test. (E) Representative transmission electron micrograph from WTSpi1 and KOSpi1 livers at P0. n=3 per genotype from 2 independent litters. GP, glycogen particle; N, nucleus. Scale bars: 5 µm.
February 2, 2026 at 2:58 PM
dev-journal.bsky.social
To learn more about this paper and the people behind it, we spoke with corresponding author @benoitbruneau.bsky.social, as well as both first and corresponding author @irfankathiriya.bsky.social, Professor of Anesthesia at the University of California, San Francisco, USA.

doi.org/10.1242/dev....
From left to right: first and corresponding author Irfan Kathiriya, Zoe Grant, Kavitha Rao and corresponding author Benoit Bruneau, piecing a puzzle. Image courtesy of Zhe Chen (Gladstone Institutes).
January 30, 2026 at 11:06 PM
dev-journal.bsky.social
Read the Research Article ‘Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease’ here:

doi.org/10.1242/dev....
January 30, 2026 at 11:06 PM
dev-journal.bsky.social
Getting to the heart of atrial cardiomyocyte identity

This Research Highlight showcases work by Irfan Kathiriya @irfankathiriya.bsky.social, Benoit Bruneau @benoitbruneau.bsky.social and colleagues at @gladstoneinst.bsky.social & @ucsfanesthesia.bsky.social

journals.biologists.com/dev/article/...
Figure 2 - Modeling genetic susceptibility to reduced TBX5 in human iPSC-derived atrial cells reveals atrial cardiomyocyte dysfunction. (A) Differentiation efficiency by flow cytometry of cTNT (**P<0.01, ***P<0.001 by two-tailed Student's t-test). (B-E) cTNT immunostaining shows sarcomeric disarray in TBX5 mutant atrial cardiomyocytes (CMs) (*P<0.05, ****P<0.0001 by two-sided Fisher's exact test). (F) Average cell area is significantly increased in TBX5 mutant atrial CMs (*P<0.05, ****P<0.0001 by two-tailed Student's t-test). Cells from two biological replicates were analyzed in E,F. (G,H) Representative action potential traces by multielectrode array (MEA) assays, based on cells from two experiments (n=6 in controls, n=20 in TBX5in/+). (I,J) Field potential and normalized local extracellular action potential (LEAP) durations at 90% (APD90) are increased in TBX5 heterozygous mutant atrial CMs (****P<0.0001 by two-sided Welch's t-test).
January 30, 2026 at 11:06 PM
dev-journal.bsky.social
Development is pleased to sponsor the upcoming Weinstein Cardiovascular Development & Regeneration Conference, taking place in New York, USA, 6-8 May 2026.

Register now: weinstein-conference.oa-event.com
Home
weinstein-conference.oa-event.com
January 29, 2026 at 3:03 PM
dev-journal.bsky.social
In preprints: shedding light – chemogenetic induction of menstruation in mice

Aishwarya V. Bhurke and Ripla Arora from @aroralab.bsky.social discuss the recent preprint by @cagricevrim.bsky.social, @karalmckinley.bsky.social and colleagues on the X-mens menstruation model.

doi.org/10.1242/dev....
January 27, 2026 at 2:48 PM
dev-journal.bsky.social
To learn more about how this paper developed and the people behind it, we talked to first author Longwei Bai and corresponding author François Leulier, Director and Group Leader at Institut de Génomique Fonctionnelle de Lyon (@igflyon.bsky.social) in France.

doi.org/10.1242/dev....
First author Longwei Bai (left) and corresponding author François Leulier (right)
January 27, 2026 at 2:36 PM
dev-journal.bsky.social
Read the Research Report ‘Ecdysone-mediated intestinal growth contributes to microbiota-driven developmental plasticity under malnutrition’ here:

doi.org/10.1242/dev....
January 27, 2026 at 2:36 PM
dev-journal.bsky.social
Bacteria-dependent ecdysone lengthens hungry stomachs

This Research Highlight showcases work from Longwei Bai (@longweibai.bsky.social), François Leulier (@francoisleulier.bsky.social) and colleagues at @igflyon.bsky.social

journals.biologists.com/dev/article/...
Supp. Fig. 1 - LpWJL mediates midgut growth through cell area increase. Representative images of anterior and posterior midguts from size-matched LpWJL-associated (D7) and GF (D11) yw larvae. Midguts were dissected and stained for Discs large (Dlg, red), a septate junction marker, and DAPI (blue) to mark nuclei. Scale bar represents 100μm.
January 27, 2026 at 2:36 PM
dev-journal.bsky.social
Development of the blood–brain barrier

In this Review, Benjamin D. Gastfriend and Richard Daneman discuss recent advances in understanding blood-brain barrier development, as well as unanswered questions in the field.

doi.org/10.1242/dev....
Figure 1 - Development of blood–brain barrier properties and control by extrinsic factors. Panel B: Time course of central nervous system (CNS) angiogenesis and BBB development in mice and zebrafish. Schematics of retina vasculature represent the superficial layer and are based on the development of the superficial vascular plexus in mouse retinas shown in Stahl et al. (2010). E, embryonic day; P, postnatal day; hpf, hours post-fertilization.
January 27, 2026 at 2:09 PM
dev-journal.bsky.social
The most recent addition to our academic team, Associate Editor Anna Bigas, will be speaking at the Dubai Stem Cell Congress that starts next week on Saturday 7 February.

Chat with Anna about publishing #haematopoiesis in Development.

journals.biologists.com/dev/pages/ed...
Anna Bigas Associate Editor, Development Hospital del Mar Research Institute (HMRIB) and Josep Carreras Leukaemia Research Institute (IJC), Spain “I look forward to handling papers on developmental haematopoiesis and haematopoietic stem cells. I can also handle Notch signalling papers in different systems, as well as papers on cancer and leukaemia mechanisms.” Key topics: development and disease haematopoiesis signalling stem cells
January 26, 2026 at 1:08 PM
dev-journal.bsky.social
Congratulations to @rashmi-priya.bsky.social on winning the 2026 Women in Cell Biology Model from @bscb-official.bsky.social.

Rashmi is a Guest Editor of our current special issue on the extracellular environment: journals.biologists.com/dev/pages/ex...

We also interviewed Rashmi in 2022⬇️
January 22, 2026 at 11:55 AM
dev-journal.bsky.social
Congratulations to @giuliapaci.bsky.social, one of our latest Pathway to Independence (PI) fellows, on winning the @bscb-official.bsky.social 2026 Postdoc Medal.

You can learn more about Giulia's research in her interview doi.org/10.1242/dev....
bscb-official.bsky.social British Society for Cell Biology @bscb-official.bsky.social · 19d
We are delighted to announce that @giuliapaci.bsky.social from @ucllifesciences.bsky.social has been awarded the 2026 BSCB Postdoctoral researcher medal

You can read about Giulia's work on how tissues withstand mechanical stress here:

bscb.org/postdoctoral...
January 22, 2026 at 11:50 AM
dev-journal.bsky.social
Development Editor Jim Wells is attending the Takeda Science Foundation symposium, 'ORGANOID 4D: Development, Disease, Diversity and Discovery', starting on Friday 23 January.

Use the opportunity to meet Jim and speak about publishing in Development.

journals.biologists.com/dev/pages/ed...
James Wells Editor, Development Cincinnati Children's Hospital Medical Center, USA “Most exciting discoveries happen at the junction between two disciplines, and two disciplines that I think really are a marriage made in heaven are developmental biology and biomedical engineering. I'd love to see more engineering-based principles applied to studying concepts in developmental biology.” Key topics: development and disease, organogenesis, patterning, stem cells, tissue engineering and organoids
January 21, 2026 at 1:19 PM
dev-journal.bsky.social
Our Editor-in-Chief, @jamesbriscoe.bsky.social, will be attending the St. Anna CCRI Symposium on Cell Fate in Cancer and Development meeting, starting on Friday 23 January.

Please speak to James about publishing your research in Development.

journals.biologists.com/dev/pages/aims
James Briscoe Editor-in-Chief , Development The Francis Crick Institute, UK “Community journals such as Development play a crucial role. Every issue of Development has papers handled by academic editors who are leaders in the field, so it offers a curated collection of the latest developmental biology research selected by experts.” Key topics: cell fate control and differentiation computational biology and modelling gene regulation and stem cells neural development and patterning tissue engineering and organoids
January 20, 2026 at 11:06 AM
Reposted by Development
dev-journal.bsky.social
📢Call for papers. Submit your latest research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells

Guest Editors: Alex Hughes and Rashmi Priya

📅 Deadline: 1 March 2026

journals.biologists.com/dev/pages/ex...

#DevBio
September 1, 2025 at 12:29 PM
dev-journal.bsky.social
Also in Issue 1:
▪️2 Research Highlights on germ line meiosis and metamorphosis evolution
▪️2 ‘People behind the papers’ interviews
▪️In Preprints’ Perspective on Cajal-Retzius cell evolution
▪️Editorial about publishing in Development

See full issue here: journals.biologists.com/dev/issue/15...
January 16, 2026 at 2:46 PM
dev-journal.bsky.social
Our first issue of Vol 153 (2026) is complete!

On the cover: 3D image of the apical Drosophila pupal eye with depth-coding applied, showing a dome-like ommatidia.

See the Research Article by Bhattarai ( @abhibhattarai.bsky.social) et al. from @ruthjohnsonlab.bsky.social

doi.org/10.1242/dev....
3D image of the apical Drosophila pupal eye with depth-coding applied and a pronounced dome-like appearance of ommatidia, owing to the highly organized network of apical rib-like actin filaments (ARAFs)
January 16, 2026 at 2:46 PM
dev-journal.bsky.social
To learn more about this paper and the people behind it, we talked to first author Hana Nagata and corresponding author Yuichiro (Yui) Suzuki, Dorothy and Charles Jenkins, Jr. Distinguished Chair in Science and Professor of Biological Sciences, @wellesley.edu, USA.

doi.org/10.1242/dev....
First author Hana Nagata (right) and corresponding author Yui Suzuki (left).
January 15, 2026 at 4:23 PM
dev-journal.bsky.social
Read the #OpenAccess Research Article “Evolution of complete metamorphosis through temporal shifts in Chronologically inappropriate morphogenesis (Chinmo) and Broad” here:

doi.org/10.1242/dev....
January 15, 2026 at 4:23 PM
dev-journal.bsky.social
chinmo provides insights into the evolution of insect metamorphosis

This Research Highlight showcases work by Hana Nagata and Yuichiro Suzuki from @wellesley.edu.

journals.biologists.com/dev/article/...
 Summary and implications for the evolution of metamorphosis. (A) Summary of results obtained from knockdown of chinmo in the first nymphal instar of O. fasciatus. chinmo knockdown results in a reduction in the number of nymphal instars, and enhanced rate of wing pad growth and morphogenesis. Gray lines highlight proposed equivalent instars based on the nymphal and adult patterns. (B) Antagonistic roles of Chinmo and Br in regulating the rate of nymphal wing pad growth. Br promotes allometric growth, while Chinmo expression in the absence of Br leads to isometric growth. (C) Model for the interactions between Chinmo, Br and E93 on nymphal maturation and adult development. (D) The separation of Chinmo and Broad function may have led to the separation of isometric growth during the larval stage and allometric growth and differentiation during metamorphosis in holometabolous insects.
January 15, 2026 at 4:23 PM