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eLife
@elife.bsky.social
The funder-researcher collaboration and open-access publisher for research in the life and biomedical sciences.

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We’re pleased to announce our Trained Immunity Focus Issue 🎉

With original research and reviews spanning history, current state and future directions of trained immunity, explore today:
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A ‘Fundamental’ study shows that brain glial progenitor cells can be reprogrammed into corticospinal-like neurons with striking accuracy, opening new paths for studying and repairing circuits damaged in ALS and spinal cord injury.
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January 4, 2026 at 11:01 AM
Bacteria swap DNA far more than we thought. This study shows recombination between species can blur genetic boundaries, with up to 95% of diversity coming from hybrid DNA in some microbes.
Remixing the gene pool
Microbes might behave less like distinct species and more like constantly interbreeding communities.
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January 4, 2026 at 9:21 AM
T cells must encounter pathogen-derived antigens directly in the skin to differentiate into optimally effective, long-lived tissue-resident memory T cells.
Total recall
T cells must encounter pathogen-derived antigens directly in the skin to differentiate into optimally effective, long-lived tissue-resident memory T cells.
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January 3, 2026 at 11:44 PM
There is a clear problem in research publishing. More and more scientists are valuing transparency, openness and integrity. If that’s you, eLife is the right choice.
January 3, 2026 at 2:59 PM
The most recognisable feature of the human brain is its folds. So why do other animals’ brains look so different?
The rise of brain folds
Differences in brain folding between species can be explained by variations in initial brain size, shape and cortical growth rate, rather than by different folding mechanisms.
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January 3, 2026 at 11:01 AM
This ‘landmark’ study is now a Version of Record! It shows the #herpes simplex virus-1 uses innovative microscopy and x-ray tomography techniques to examine the roles of 9 proteins in viral formation.
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January 2, 2026 at 9:01 PM
eLife complies with all major funding agency requirements for #OpenAccess:

✅ Openly available at the point of publication
✅ CC-BY or CC0 licences
✅ Deposited to PubMed Central and other repositories
✅ Published with funding info

Our policies: buff.ly/HtKgHTq
January 2, 2026 at 2:59 PM
Reposted by eLife
December 28, 2025 at 9:32 AM
Reposted by eLife
Happy that our work on the evolution of Yellowstone cyanobacteria is now published in @elife.bsky.social: doi.org/10.7554/eLif...! Did a lot of work in revision—many thanks to the anonymous reviewers for great suggestions! Also see the eLife digest for a summary: elifesciences.org/digests/9084...
Hybridization breaks species barriers in long-term coevolution of a cyanobacterial population
Analysis of hundreds of single-cell genomes from Yellowstone National Park shows bacterial species are less cohesive than previously thought.
doi.org
December 31, 2025 at 9:15 PM
Reposted by eLife
2025 ended with a blast as the version of record of the paper was officially published by @elife.bsky.social at 19h19 on the 31st of December 🥳
doi.org/10.7554/eLif...

Be prepared for some cognitive control and modelling follow-ups in 2026 and a happy new year to y'all.
January 1, 2026 at 11:27 AM
Modelling shows that microorganisms using cilia or flagella can feed just as effectively whether they swim freely or attach and generate feeding currents, helping explain why both strategies persist in nature.
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January 1, 2026 at 11:28 PM
A study in the chick auditory brainstem shows that differences between oligodendrocytes help set the spacing of myelin along axons, fine-tuning the timing needed for accurate sound localisation.
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January 1, 2026 at 9:01 PM
This study shows that differences between oligodendrocytes, the cells that make myelin, shape how nodes of Ranvier are spaced along axons in the chick auditory brainstem, helping control signal speed with remarkable precision.
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January 1, 2026 at 2:44 PM
In Dictyostelium, this study demonstrates that an enzyme that converts adenosine into ammonia plays a crucial role in triggering tip formation.
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December 31, 2025 at 11:28 PM
Traditional publishing can take months to years. How does publishing with eLife help researchers on a deadline?
December 31, 2025 at 4:16 PM
We feel guilt and shame when we do something we think is wrong. These feelings depend on the magnitude of harm we cause and our level of responsibility. How do these interact and drive our resulting behaviour?
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December 31, 2025 at 11:01 AM
We train scientists to ask questions. Now they’re asking: “Is there a better way?”

Research culture scholar Fátima Sancheznieto joins Voices to talk about challenging norms and building evidence-based systems to improve academic training.
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December 30, 2025 at 9:02 PM
As part of our efforts to make science more reproducible, we integrate Bio-protocol in our methods sections so you can easily view or request detailed protocols directly from any eLife article. #Reproducibility #OpenScience

Read more ⬇️
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December 30, 2025 at 4:11 PM
Can you infer cause and effect between genes without disturbing the cell? 🧬

This study shows how natural “noise” in gene expression can reveal directed gene–gene interactions.
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December 30, 2025 at 11:01 AM
Are peer reviewers influenced by their work being cited?
Coercive citations
Reviewer citation requests can turn peer review into a transaction rather than an objective critique of the article.
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December 29, 2025 at 11:28 PM
Already posting preprints?

At eLife, our expert editors and reviewers discuss and prepare reviews to be shared publicly, providing quality, constructive feedback that helps the community build on your work.

Learn more about peer review at eLife ⬇️
Peer review and publishing at eLife · eLife
eLife is pioneering an approach to scientific publishing that combines the immediacy and openness of preprints with the scrutiny of peer review by experts.
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December 29, 2025 at 9:01 PM
Kangaroos have a remarkable ability to speed up without burning extra energy.

Clever posture changes let their tendons store and return extra elastic energy, acting like natural springs and keeping the metabolic cost almost flat even at higher speeds.
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December 29, 2025 at 11:44 AM
Open Journal Systems (OJS) is used by over 52,000 journals in 150+ countries and in 60 languages. Hear how a spirit of public service led to a quiet revolution in research access.

Listen to John Willinsky in Voices wherever you get your podcasts.
Community | eLife Community Voices | Episode 6 · eLife
John Willinsky recounts his journey from schoolteacher to open access pioneer.
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December 28, 2025 at 11:28 PM
Zinc plays a crucial role in early embryo development.

This study demonstrates that a zinc transporter in mouse eggs is essential after fertilisation for embryos to continue developing, underscoring zinc's crucial role in the earliest stages of life.
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December 28, 2025 at 11:01 AM
A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers.
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December 28, 2025 at 9:21 AM