Engineered “migrasomes” show promise as a stable, room-temperature vaccine platform, triggering strong immune responses in mice and potentially easing cold-chain challenges.
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⛓️ October’s most-read Structural Biology paper challenges textbook views of synapses, revealing a complex ‘synaptoplasm’ instead of a dense post-synaptic layer: buff.ly/rAvREVV

Have a paper people should see? See what our Editors look for: buff.ly/NjxVKFB

Migration of cell populations is a fundamental process in morphogenesis and disease. Researchers have identified a novel form of collective mesenchymal cell migration during chick gastrulation, where cells self-organise into a dynamic meshwork structure.
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Septins and the exocyst complex work together to guide membrane trafficking during cell division in fission yeast, revealing one of the most conserved functions of septins in exocytosis.
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1/ New ‘fundamental’ study shows that neuronal migration depends on blood flow in the adult mammalian brain.
elifesciences.org/articles/995...

For most of us, our physical and mental abilities decline as we age.

Scientists are examining tool use, a technically challenging activity, to learn how ageing affects our close relatives, chimpanzees, something we know very little about.
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By comparing differently tuned glomeruli, this work shows that the brain uses different circuit layouts for specialised vs general smells, offering new insight into how odour meaning is encoded.
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