Tim Rhoads
@timwrhoads.bsky.social
Assistant Professor, Dept. of Nutritional Sciences, UW-Madison. Metabolism, RNA, and aging. All opinions my own (and not my employers).
Pinned
Tim Rhoads
@timwrhoads.bsky.social
· Nov 8
Trying to find all the metabolism/mito folks on here, so i created a starter pack. Please suggest anyone I missed!
go.bsky.app/C2t7snh
go.bsky.app/C2t7snh
Reposted by Tim Rhoads
The final Calvin and Hobbes, which appeared in papers 30 years ago today.
December 31, 2025 at 5:00 PM
The final Calvin and Hobbes, which appeared in papers 30 years ago today.
Reposted by Tim Rhoads
Online Now: RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria Online now:
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria
This study introduces CRASP-seq, an RNA-coupled CRISPR screening platform designed to systematically identify regulatory factors and domains of alternative pre-mRNA splicing. Using this technology, ZNF207 is identified as a bona fide splicing regulator through its interaction with U1 snRNP components. ZNF207 modulates aberrant LMNA splicing, a critical event linked to progeria.
dlvr.it
December 30, 2025 at 4:19 PM
Online Now: RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria Online now:
Reposted by Tim Rhoads
scoop: During a heated conference call this spring, the head of the Corporation for Public Broadcasting told Katherine Maher, the C.E.O. of NPR, that she should resign.
My profile of Katherine Maher, which goes behind-the-scenes of the most consequential fight in NPR’s history.
My profile of Katherine Maher, which goes behind-the-scenes of the most consequential fight in NPR’s history.
December 30, 2025 at 12:24 PM
scoop: During a heated conference call this spring, the head of the Corporation for Public Broadcasting told Katherine Maher, the C.E.O. of NPR, that she should resign.
My profile of Katherine Maher, which goes behind-the-scenes of the most consequential fight in NPR’s history.
My profile of Katherine Maher, which goes behind-the-scenes of the most consequential fight in NPR’s history.
Reposted by Tim Rhoads
it's completely bullshit that if I am paying open access fees, that the journals are not depositing the paper into NCBI.
December 29, 2025 at 6:17 PM
it's completely bullshit that if I am paying open access fees, that the journals are not depositing the paper into NCBI.
Reposted by Tim Rhoads
@acs.org has still not returned its inclusivity guides based on race/ethnicity or gender/sex/sexual-orientation/gender-identity. The idea that they "paused" them for "review and refinement" was a cover for caving to the Trump administration. @professor-dave.bsky.social
www.acs.org/about/inclus...
www.acs.org/about/inclus...
December 25, 2025 at 1:44 AM
@acs.org has still not returned its inclusivity guides based on race/ethnicity or gender/sex/sexual-orientation/gender-identity. The idea that they "paused" them for "review and refinement" was a cover for caving to the Trump administration. @professor-dave.bsky.social
www.acs.org/about/inclus...
www.acs.org/about/inclus...
Reposted by Tim Rhoads
New preprint! We found that the flavin-dependent halogenase RebH catalyzes sequence-tolerant Trp bromination in peptides 🧪https://www.biorxiv.org/content/10.64898/2025.12.17.694899v1
December 21, 2025 at 3:58 AM
New preprint! We found that the flavin-dependent halogenase RebH catalyzes sequence-tolerant Trp bromination in peptides 🧪https://www.biorxiv.org/content/10.64898/2025.12.17.694899v1
Reposted by Tim Rhoads
New in ACS SynBio: led by Dennis Bolshakov, we used the awesome power of yeast to define how expression levels, noise, and sequence program the dynamics of synthetic protein waves, allowing us to genetically encode new cellular timescales stable over generations!
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
December 17, 2025 at 3:24 PM
New in ACS SynBio: led by Dennis Bolshakov, we used the awesome power of yeast to define how expression levels, noise, and sequence program the dynamics of synthetic protein waves, allowing us to genetically encode new cellular timescales stable over generations!
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Reposted by Tim Rhoads
Christmas-physics cross-over joke
December 22, 2025 at 10:49 AM
Christmas-physics cross-over joke
Reposted by Tim Rhoads
I’m laid up with the flu, but I had to peek my head out and say that this is *so* much worse than it seems.
And it’s already pretty fucking bad!
bsky.app/profile/gbbr...
And it’s already pretty fucking bad!
bsky.app/profile/gbbr...
"Has feminism failed women brought to you by bank of america" is my MKULTRA sleeper agent activation phrase
December 20, 2025 at 10:56 PM
I’m laid up with the flu, but I had to peek my head out and say that this is *so* much worse than it seems.
And it’s already pretty fucking bad!
bsky.app/profile/gbbr...
And it’s already pretty fucking bad!
bsky.app/profile/gbbr...
Reposted by Tim Rhoads
Presenting, attending or excited to learn?
#ASBMB26 is all about scientific exchange, collaboration and inspiration.
Introduce yourself using this social media toolkit and meet fellow attendees before the conference kicks off — counting down to March!
www.asbmb.org/annual... #MakeItPossible
#ASBMB26 is all about scientific exchange, collaboration and inspiration.
Introduce yourself using this social media toolkit and meet fellow attendees before the conference kicks off — counting down to March!
www.asbmb.org/annual... #MakeItPossible
December 20, 2025 at 9:47 PM
Presenting, attending or excited to learn?
#ASBMB26 is all about scientific exchange, collaboration and inspiration.
Introduce yourself using this social media toolkit and meet fellow attendees before the conference kicks off — counting down to March!
www.asbmb.org/annual... #MakeItPossible
#ASBMB26 is all about scientific exchange, collaboration and inspiration.
Introduce yourself using this social media toolkit and meet fellow attendees before the conference kicks off — counting down to March!
www.asbmb.org/annual... #MakeItPossible
Reposted by Tim Rhoads
A Trump administration change to how the National Institutes of Health awards grants has sharply reduced early-stage investigators’ odds of securing funding, new data from the agency show. Teamed up with @aniloza.bsky.social for this @statnews.com story
www.statnews.com/2025/12/18/n...
www.statnews.com/2025/12/18/n...
NIH funding rates for early-career researchers plunged in 2025, new data show
A Trump administration change to how NIH awards grants has sharply reduced early-stage investigators’ odds of securing funding.
www.statnews.com
December 18, 2025 at 8:01 PM
A Trump administration change to how the National Institutes of Health awards grants has sharply reduced early-stage investigators’ odds of securing funding, new data from the agency show. Teamed up with @aniloza.bsky.social for this @statnews.com story
www.statnews.com/2025/12/18/n...
www.statnews.com/2025/12/18/n...
Reposted by Tim Rhoads
Chromatin buffers torsional stress during transcription | Science www.science.org/doi/10.1126/...
Chromatin buffers torsional stress during transcription
During eukaryotic transcription, Pol II must overcome nucleosome obstacles and, because of DNA’s helical structure, must also rotate relative to DNA, generating torsional stress. However, there is lim...
www.science.org
December 18, 2025 at 7:14 PM
Chromatin buffers torsional stress during transcription | Science www.science.org/doi/10.1126/...
Reposted by Tim Rhoads
I've spent all day struggling to write a single page of a popular science article. I bang away at a word processor; give up; start diagramming on paper. Take some notes; draft a few sentences in pen; return to the computer...and very slowly I figure out what I was trying to say in the first place.
December 16, 2025 at 11:41 PM
I've spent all day struggling to write a single page of a popular science article. I bang away at a word processor; give up; start diagramming on paper. Take some notes; draft a few sentences in pen; return to the computer...and very slowly I figure out what I was trying to say in the first place.
Reposted by Tim Rhoads
With a vibrant program featuring cutting-edge research and interdisciplinary collaboration, the 2026 ASBMB Annual Meeting offers unparalleled opportunities to deepen your expertise and broaden your impact.
☑️ Register early (by Feb. 3) and save: www.asbmb.org/annual-meeti.... #ASBMB26
☑️ Register early (by Feb. 3) and save: www.asbmb.org/annual-meeti.... #ASBMB26
December 17, 2025 at 9:55 PM
With a vibrant program featuring cutting-edge research and interdisciplinary collaboration, the 2026 ASBMB Annual Meeting offers unparalleled opportunities to deepen your expertise and broaden your impact.
☑️ Register early (by Feb. 3) and save: www.asbmb.org/annual-meeti.... #ASBMB26
☑️ Register early (by Feb. 3) and save: www.asbmb.org/annual-meeti.... #ASBMB26
Reposted by Tim Rhoads
Broadening engagement in BMB
This #ASBMB26 symposium features speakers sharing innovative strategies to broaden engagement in BMB through inclusive teaching and mentoring, career training, and institutional policies & programs.
➡️ Explore the program: www.asbmb.org/annual-meeti....
#MakeItPossible
This #ASBMB26 symposium features speakers sharing innovative strategies to broaden engagement in BMB through inclusive teaching and mentoring, career training, and institutional policies & programs.
➡️ Explore the program: www.asbmb.org/annual-meeti....
#MakeItPossible
December 16, 2025 at 10:27 PM
Broadening engagement in BMB
This #ASBMB26 symposium features speakers sharing innovative strategies to broaden engagement in BMB through inclusive teaching and mentoring, career training, and institutional policies & programs.
➡️ Explore the program: www.asbmb.org/annual-meeti....
#MakeItPossible
This #ASBMB26 symposium features speakers sharing innovative strategies to broaden engagement in BMB through inclusive teaching and mentoring, career training, and institutional policies & programs.
➡️ Explore the program: www.asbmb.org/annual-meeti....
#MakeItPossible
Reposted by Tim Rhoads
Just decline the peer review invitation.
What are you people even doing?
What are you people even doing?
More than half of researchers now use AI for peer review — often against guidance
A survey of 1,600 academics found that more than 50% have used artificial-intelligence tools while peer reviewing manuscripts.
www.nature.com
December 16, 2025 at 10:39 PM
Just decline the peer review invitation.
What are you people even doing?
What are you people even doing?
Reposted by Tim Rhoads
All living organisms face the problem of parasites - but what happens when DNA has invaded the genome?
go.nature.com/3MDiJCq
go.nature.com/3MDiJCq
SOS: RNA-processing mechanism rescues genes from invasive DNA
Transposable elements can insert into genes, disrupting protein-coding potential. Researchers discover a mode of RNA processing, ‘SOS splicing’, that provides a quick fix.
go.nature.com
December 16, 2025 at 11:34 AM
All living organisms face the problem of parasites - but what happens when DNA has invaded the genome?
go.nature.com/3MDiJCq
go.nature.com/3MDiJCq
Reposted by Tim Rhoads
Rob Reiner: I'm going to make a coming of age drama, a fantasy adventure story, a romantic comedy, a psychological horror and then a courtroom drama.
Us: Across your entire career?
Reiner: In a 6 year period.
Us: That sounds-
Reiner: -Each one will be arguably the best movie in that genre.
Us: Across your entire career?
Reiner: In a 6 year period.
Us: That sounds-
Reiner: -Each one will be arguably the best movie in that genre.
December 15, 2025 at 8:04 AM
Rob Reiner: I'm going to make a coming of age drama, a fantasy adventure story, a romantic comedy, a psychological horror and then a courtroom drama.
Us: Across your entire career?
Reiner: In a 6 year period.
Us: That sounds-
Reiner: -Each one will be arguably the best movie in that genre.
Us: Across your entire career?
Reiner: In a 6 year period.
Us: That sounds-
Reiner: -Each one will be arguably the best movie in that genre.
Reposted by Tim Rhoads
I am often asked what laws I would recommend blue states adopt. While there is no one-size-fits-all approach, there are seven changes every state could adopt right now, for virtually no cost or administrative burden. www.democracydocket.com/opinion/seve...
Seven Voting Laws Every Blue State Should Enact Right Now
Read more here.
www.democracydocket.com
December 14, 2025 at 11:51 PM
I am often asked what laws I would recommend blue states adopt. While there is no one-size-fits-all approach, there are seven changes every state could adopt right now, for virtually no cost or administrative burden. www.democracydocket.com/opinion/seve...
Reposted by Tim Rhoads
Reposted by Tim Rhoads
I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...
PAR-26-121: Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)
files.simpler.grants.gov
December 11, 2025 at 6:48 PM
I think some folks might be happy to see this. NIGMS MIRA R35 for EI/NI has been published. PAR-26-121 files.simpler.grants.gov/opportunitie...
Reposted by Tim Rhoads
YOUR STUDENTS ARE NOT YOUR CUSTOMERS.
Get the fuck out of education if that's the way you're talking about them.
Get the fuck out of education if that's the way you're talking about them.
Yes we all agree that this is the reason colleges are in trouble
December 9, 2025 at 5:14 PM
YOUR STUDENTS ARE NOT YOUR CUSTOMERS.
Get the fuck out of education if that's the way you're talking about them.
Get the fuck out of education if that's the way you're talking about them.
Reposted by Tim Rhoads
This is actually a good example of why the customer model is wrong.
I wouldn't have chosen poetry writing, but UNC made me take a class. And it absolutely made me become a much better writer, with an eye to concision and an ear now trained to the rhythm of words. I'm a better historian as a result.
I wouldn't have chosen poetry writing, but UNC made me take a class. And it absolutely made me become a much better writer, with an eye to concision and an ear now trained to the rhythm of words. I'm a better historian as a result.
If you are providing me with an education that is low utility in the world then it’s a disservice. My composition class spent four weeks on poetry. I’m sorry, but that only would’ve been useful if I wanted to be a poet. I don’t need to know iambic pentameter in order to be a victim advocate.
December 9, 2025 at 7:17 PM
This is actually a good example of why the customer model is wrong.
I wouldn't have chosen poetry writing, but UNC made me take a class. And it absolutely made me become a much better writer, with an eye to concision and an ear now trained to the rhythm of words. I'm a better historian as a result.
I wouldn't have chosen poetry writing, but UNC made me take a class. And it absolutely made me become a much better writer, with an eye to concision and an ear now trained to the rhythm of words. I'm a better historian as a result.
Reposted by Tim Rhoads
Deadline is almost here!
Apply for the AGE Early Career Scholar’s Program before Dec 10.
Winners receive:
• 2-yr AGE membership
• $1300 travel award (AGE 2026)
• Chance to present research
• Mentorship from senior scholars
Apply now 👉 age.memberclicks.net
#AgingResearch #AGECommunity #Geroscience
Apply for the AGE Early Career Scholar’s Program before Dec 10.
Winners receive:
• 2-yr AGE membership
• $1300 travel award (AGE 2026)
• Chance to present research
• Mentorship from senior scholars
Apply now 👉 age.memberclicks.net
#AgingResearch #AGECommunity #Geroscience
December 3, 2025 at 8:08 PM
Deadline is almost here!
Apply for the AGE Early Career Scholar’s Program before Dec 10.
Winners receive:
• 2-yr AGE membership
• $1300 travel award (AGE 2026)
• Chance to present research
• Mentorship from senior scholars
Apply now 👉 age.memberclicks.net
#AgingResearch #AGECommunity #Geroscience
Apply for the AGE Early Career Scholar’s Program before Dec 10.
Winners receive:
• 2-yr AGE membership
• $1300 travel award (AGE 2026)
• Chance to present research
• Mentorship from senior scholars
Apply now 👉 age.memberclicks.net
#AgingResearch #AGECommunity #Geroscience
Reposted by Tim Rhoads
This afternoon, I was in a meeting with Jay Bhattacharya, and I can confirm this is *exactly* what he both wants and will be doing.
THIS IS NOT HYPERBOLE.
THIS IS NOT HYPERBOLE.
I missed this from a couple of weeks ago, but if you're an NIH-funded investigator, please read.
Peer review will exist to make things look legitimate, but can, and will, be over-ruled. Funding decisions, ultimately, will be done by political appointees.
grants.nih.gov/news-events/...
Peer review will exist to make things look legitimate, but can, and will, be over-ruled. Funding decisions, ultimately, will be done by political appointees.
grants.nih.gov/news-events/...
Implementing a Unified NIH Funding Strategy to Guide Consistent and Clearer Award Decisions | Grants & Funding
grants.nih.gov
December 5, 2025 at 10:07 PM
This afternoon, I was in a meeting with Jay Bhattacharya, and I can confirm this is *exactly* what he both wants and will be doing.
THIS IS NOT HYPERBOLE.
THIS IS NOT HYPERBOLE.