Tim Rhoads
@timwrhoads.bsky.social
Assistant Professor, Dept. of Nutritional Sciences, UW-Madison. Metabolism, RNA, and aging. All opinions my own (and not my employers).
Pinned
Tim Rhoads
@timwrhoads.bsky.social
· Nov 8
Trying to find all the metabolism/mito folks on here, so i created a starter pack. Please suggest anyone I missed!
go.bsky.app/C2t7snh
go.bsky.app/C2t7snh
Reposted by Tim Rhoads
the only good accent work on earth is old money transatlantic american to make fun of rich people accent
November 13, 2025 at 4:06 PM
the only good accent work on earth is old money transatlantic american to make fun of rich people accent
Reposted by Tim Rhoads
www.nature.com/articles/s41...
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy - Nature
Acetyl-coenzyme A functions as a non-canonical signal to trigger mitophagy, and the acetyl-coenzyme A–NLRX1 axis underlies the KRAS-inhibitor-induced mitophagy response and promotes drug resistan...
www.nature.com
November 12, 2025 at 6:02 PM
www.nature.com/articles/s41...
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
Reposted by Tim Rhoads
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
November 6, 2025 at 1:11 PM
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
Reposted by Tim Rhoads
Following a recent article about the different layers of conceptualisation in a science project, this is about a pet peeve of mine. I would love to hear your views.
network.febs.org/posts/thinki...
network.febs.org/posts/thinki...
Thinking like a Scientist: The Limits of Genome Editing and Omics
Second part of Thinking like a Scientist, reflecting on how genome editing and multi-omics, while powerful, can introduce conceptual flaws that distort our understanding of gene function and biologica...
network.febs.org
November 4, 2025 at 11:21 AM
Following a recent article about the different layers of conceptualisation in a science project, this is about a pet peeve of mine. I would love to hear your views.
network.febs.org/posts/thinki...
network.febs.org/posts/thinki...
Reposted by Tim Rhoads
How's your juggling act? Mitochondria also have one, and the MITOtalk this week will be all about it.
See you there?
See you there?
November 4, 2025 at 2:11 PM
How's your juggling act? Mitochondria also have one, and the MITOtalk this week will be all about it.
See you there?
See you there?
Reposted by Tim Rhoads
Higher ed and science journalists - this is the first report I've seen that the UC is thinking about cutting their internal postdoc program, which has been a roaring success. Something to look into?
UC Provost Katherine Newman has announced plans to defund this program, a preemptive capitulation with the feds that has not been ordered and should not occur. Newman has done this with zero consultation with campus-level leadership and none with any faculty — mentors or former fellows included.
November 2, 2025 at 10:01 PM
Higher ed and science journalists - this is the first report I've seen that the UC is thinking about cutting their internal postdoc program, which has been a roaring success. Something to look into?
Reposted by Tim Rhoads
The President’s Postdoctoral Fellowship Program, PPFP, has been a jewel in the crown for faculty development and recruitment at the University of California for years and the results have been an expanded faculty with almost 100% tenure rates — unprecedented success.
November 2, 2025 at 11:01 AM
The President’s Postdoctoral Fellowship Program, PPFP, has been a jewel in the crown for faculty development and recruitment at the University of California for years and the results have been an expanded faculty with almost 100% tenure rates — unprecedented success.
Reposted by Tim Rhoads
Reposted by Tim Rhoads
Our paper in Science is out! @souravagrawal.bsky.social, @rlynn.bsky.social, @susvirkar.bsky.social, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. www.science.org/doi/10.1126/...
Human RPA is an essential telomerase processivity factor for maintaining telomeres
Telomerase counteracts telomere shortening by repeatedly adding DNA repeats to chromosome ends. We identified the replication protein A (RPA) heterotrimer as a telomerase processivity factor critical ...
www.science.org
October 30, 2025 at 10:07 PM
Our paper in Science is out! @souravagrawal.bsky.social, @rlynn.bsky.social, @susvirkar.bsky.social, and the rest of the team show human RPA is a telomerase processivity factor essential for telomere maintenance. This reshapes our thinking about telomerase regulation. www.science.org/doi/10.1126/...
Reposted by Tim Rhoads
Congratulations @cijilim.bsky.social lab!
Human RPA is an essential telomerase processivity factor for maintaining telomeres | Science www.science.org/doi/10.1126/...
Human RPA is an essential telomerase processivity factor for maintaining telomeres | Science www.science.org/doi/10.1126/...
Human RPA is an essential telomerase processivity factor for maintaining telomeres
Telomerase counteracts telomere shortening by repeatedly adding DNA repeats to chromosome ends. We identified the replication protein A (RPA) heterotrimer as a telomerase processivity factor critical ...
www.science.org
October 30, 2025 at 6:11 PM
Congratulations @cijilim.bsky.social lab!
Human RPA is an essential telomerase processivity factor for maintaining telomeres | Science www.science.org/doi/10.1126/...
Human RPA is an essential telomerase processivity factor for maintaining telomeres | Science www.science.org/doi/10.1126/...
Reposted by Tim Rhoads
"It's past time to recognize that university administrators aren't going to lead the way out of this, [setting] the stage for leadership... from faculty, staff, & students, [where] most if not all progress in higher ed over the past 100 yrs has occurred."
www.science.org/doi/10.1126/...
#AcademicSky
www.science.org/doi/10.1126/...
#AcademicSky
Higher education fails at collective action
In the latest development in the ongoing combat between universities in the United States and the Trump administration, the Department of Education has presented them with what it calls a “compact.” I...
www.science.org
October 27, 2025 at 7:14 PM
"It's past time to recognize that university administrators aren't going to lead the way out of this, [setting] the stage for leadership... from faculty, staff, & students, [where] most if not all progress in higher ed over the past 100 yrs has occurred."
www.science.org/doi/10.1126/...
#AcademicSky
www.science.org/doi/10.1126/...
#AcademicSky
Reposted by Tim Rhoads
Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.
June 19, 2025 at 11:21 AM
Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.
Reposted by Tim Rhoads
Stop fighting your faculty in court, lady.
“We are committed to being transparent about the challenges facing the university, but we must also evaluate our response to the administration’s settlement proposal that, like all settlement communications, is confidential.
“We are committed to being transparent about the challenges facing the university, but we must also evaluate our response to the administration’s settlement proposal that, like all settlement communications, is confidential.
October 23, 2025 at 3:12 PM
Stop fighting your faculty in court, lady.
“We are committed to being transparent about the challenges facing the university, but we must also evaluate our response to the administration’s settlement proposal that, like all settlement communications, is confidential.
“We are committed to being transparent about the challenges facing the university, but we must also evaluate our response to the administration’s settlement proposal that, like all settlement communications, is confidential.
Reposted by Tim Rhoads
I just learned about this amazing program that matches high schoolers interested in STEM with mentors, including many past and present NIH trainees. These types of programs are even more important in this day and age. If you're able to help support it, they have a gofundme.
Donate to Support PATHS: Mentorship Program for STEM High Schoolers, organized by PATHS Mentorship
The Program for Advancing The Health Sciences (PATHS) is a Vi… PATHS Mentorship needs your support for Support PATHS: Mentorship Program for STEM High Schoolers
gofund.me
October 25, 2025 at 5:01 PM
I just learned about this amazing program that matches high schoolers interested in STEM with mentors, including many past and present NIH trainees. These types of programs are even more important in this day and age. If you're able to help support it, they have a gofundme.
Reposted by Tim Rhoads
ASBMB thrives thanks to member volunteers. Nominate a colleague—or yourself—for an elected position by Nov. 5 and help shape the future of molecular life science!
➡️ Learn more: asbmb.secure-platfor....
➡️ Learn more: asbmb.secure-platfor....
October 25, 2025 at 12:00 PM
ASBMB thrives thanks to member volunteers. Nominate a colleague—or yourself—for an elected position by Nov. 5 and help shape the future of molecular life science!
➡️ Learn more: asbmb.secure-platfor....
➡️ Learn more: asbmb.secure-platfor....
Reposted by Tim Rhoads
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
mRNA initiation and termination are spatially coordinated
Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage o...
www.science.org
October 10, 2025 at 6:14 PM
Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...
Reposted by Tim Rhoads
Possibly weirded out my long-suffering colleagues with this idiosyncratic observation last week, and feel like it belongs in a meme.
#rstats #python #ripdavidlynch
#rstats #python #ripdavidlynch
October 24, 2025 at 12:07 PM
Possibly weirded out my long-suffering colleagues with this idiosyncratic observation last week, and feel like it belongs in a meme.
#rstats #python #ripdavidlynch
#rstats #python #ripdavidlynch
Reposted by Tim Rhoads
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 4:36 PM
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Reposted by Tim Rhoads
Reposted by Tim Rhoads
The university as an institution does not function without faculty governance. You can call it a university but thats not what you have.
October 23, 2025 at 1:54 PM
The university as an institution does not function without faculty governance. You can call it a university but thats not what you have.
Reposted by Tim Rhoads
Hi Everyone for the @asbmb.bsky.social 2026 annual meeting there is now a deferred payment option for federal employees and scientists impacted by the government shutdown. Information below and further details at the link.
www.asbmb.org/annual-meeti...
www.asbmb.org/annual-meeti...
Abstracts
www.asbmb.org
October 23, 2025 at 2:23 PM
Hi Everyone for the @asbmb.bsky.social 2026 annual meeting there is now a deferred payment option for federal employees and scientists impacted by the government shutdown. Information below and further details at the link.
www.asbmb.org/annual-meeti...
www.asbmb.org/annual-meeti...
Reposted by Tim Rhoads
Okay still on my soapbox but this is what happens when university financial decisions are made by board members who do not work at the university or value the mission of the university to do teaching and research. S/o @dennismhogan.bsky.social
www.chronicle.com/article/the-...
www.chronicle.com/article/the-...
October 22, 2025 at 3:31 PM
Okay still on my soapbox but this is what happens when university financial decisions are made by board members who do not work at the university or value the mission of the university to do teaching and research. S/o @dennismhogan.bsky.social
www.chronicle.com/article/the-...
www.chronicle.com/article/the-...
Reposted by Tim Rhoads
@aaas What is your response??--I am an AAAS Fellow and also find this VERY disappointing
On Sept 17th, 2025, @aaas.org and @researchamerica.bsky.social hosted Jay Bhattacharya—NIH Director—as the keynote for the National Health Research Forum.
Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means.
I have a call to action:
Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means.
I have a call to action:
October 22, 2025 at 12:35 AM
@aaas What is your response??--I am an AAAS Fellow and also find this VERY disappointing
Reposted by Tim Rhoads
On Sept 17th, 2025, @aaas.org and @researchamerica.bsky.social hosted Jay Bhattacharya—NIH Director—as the keynote for the National Health Research Forum.
Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means.
I have a call to action:
Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means.
I have a call to action:
October 21, 2025 at 11:53 PM
On Sept 17th, 2025, @aaas.org and @researchamerica.bsky.social hosted Jay Bhattacharya—NIH Director—as the keynote for the National Health Research Forum.
Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means.
I have a call to action:
Less than two weeks later, he spoke at the MAHA Action hour alongside Oz, Russel Brand, Tony Lyons, and Callie Means.
I have a call to action:
Reposted by Tim Rhoads
what you always wanted to know about the molecular choreography of nuclear mRNA packaging and export.
thought-provoking review by our colleagues (local or in the RNA community).
@plaschkalab.bsky.social
@rupertfaraway.bsky.social
@thezenklusen.bsky.social
www.annualreviews.org/content/jour...
thought-provoking review by our colleagues (local or in the RNA community).
@plaschkalab.bsky.social
@rupertfaraway.bsky.social
@thezenklusen.bsky.social
www.annualreviews.org/content/jour...
Mechanisms of Messenger RNA Packaging and Export
The packaging and export of messenger RNA (mRNA) are essential cellular pathways that bridge the nuclear and cytoplasmic phases of eukaryotic gene expression. During their nuclear maturation, mRNAs ar...
www.annualreviews.org
October 18, 2025 at 3:08 PM
what you always wanted to know about the molecular choreography of nuclear mRNA packaging and export.
thought-provoking review by our colleagues (local or in the RNA community).
@plaschkalab.bsky.social
@rupertfaraway.bsky.social
@thezenklusen.bsky.social
www.annualreviews.org/content/jour...
thought-provoking review by our colleagues (local or in the RNA community).
@plaschkalab.bsky.social
@rupertfaraway.bsky.social
@thezenklusen.bsky.social
www.annualreviews.org/content/jour...