Roland Dunbrack 🏳️🌈
@rolanddunbrack.bsky.social
Computational structural biologist @Fox Chase Cancer Center. Gay, out & proud since 1986. I support transgender & nonbinary people. Living with CLL/SLL. Video about my LGBTQ+ life in science: https://tinyurl.com/45srzjdw. Views my own, not my employer's.
@fetterman.senate.gov I hope Conor Lamb decimates you in your 2028 primary election. A lot of pain was caused by the shutdown and Democrats got nothing for working people bc of you and 7 other weasels.
Signed: Pennsylvania voter.
Signed: Pennsylvania voter.
November 10, 2025 at 6:51 PM
@fetterman.senate.gov I hope Conor Lamb decimates you in your 2028 primary election. A lot of pain was caused by the shutdown and Democrats got nothing for working people bc of you and 7 other weasels.
Signed: Pennsylvania voter.
Signed: Pennsylvania voter.
I bet Fetterman caved.
November 10, 2025 at 3:22 AM
I bet Fetterman caved.
Reposted by Roland Dunbrack 🏳️🌈
I’m stuck in bed between chemo treatments for metastatic coloncancer, wearing a take-home chemo pump attached to my chest.
I wanted to share my advice that you can benefit from ‘Letting Your Colleagues In’ don’t need to struggle alone
@insidehighered.com
www.insidehighered.com/opinion/care...
I wanted to share my advice that you can benefit from ‘Letting Your Colleagues In’ don’t need to struggle alone
@insidehighered.com
www.insidehighered.com/opinion/care...
Consider Sharing Health Challenges With Colleagues (opinion)
Being open with my colleagues about my cancer diagnosis has allowed me to access an enormous source of support and comfort.
www.insidehighered.com
November 6, 2025 at 3:15 PM
I’m stuck in bed between chemo treatments for metastatic coloncancer, wearing a take-home chemo pump attached to my chest.
I wanted to share my advice that you can benefit from ‘Letting Your Colleagues In’ don’t need to struggle alone
@insidehighered.com
www.insidehighered.com/opinion/care...
I wanted to share my advice that you can benefit from ‘Letting Your Colleagues In’ don’t need to struggle alone
@insidehighered.com
www.insidehighered.com/opinion/care...
Reposted by Roland Dunbrack 🏳️🌈
So excited that the theme of LGBT+ History Month UK 2026 is 'Science and Innovation,' with super badge designed by @canopyrobin.com! 🧬🏳️⚧️🔭🏳️🌈🚆
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
LGBT+ History Month 2026 - LGBT+ History Month
If you’d like to donate to support our work, click here to donate via PayPal. Free Schools Presentation For 2026 we are able to offer free LGBT+ History Month presentations for secondary schools, prid...
lgbtplushistorymonth.co.uk
November 7, 2025 at 9:01 PM
So excited that the theme of LGBT+ History Month UK 2026 is 'Science and Innovation,' with super badge designed by @canopyrobin.com! 🧬🏳️⚧️🔭🏳️🌈🚆
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏
lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️
There were a few years when I thought I can’t be gay & an academic scientist at the same time. James Watson pushed the view that only certain people can be scientists - basically straight white men. Fortunately in most places his view is not taken seriously anymore. But we have to remain on guard.
November 8, 2025 at 1:53 AM
There were a few years when I thought I can’t be gay & an academic scientist at the same time. James Watson pushed the view that only certain people can be scientists - basically straight white men. Fortunately in most places his view is not taken seriously anymore. But we have to remain on guard.
Reposted by Roland Dunbrack 🏳️🌈
When people celebrate the individual genius of folks in science, they should also
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
November 7, 2025 at 11:43 PM
When people celebrate the individual genius of folks in science, they should also
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
mourn the collective loss of genius of folks who were actively discouraged or disadvantaged from a career in science because of the same person(s)
Watson had it all: misogyny, racism, anti-Semitism, homophobia. He would have been anti-trans if he’d heard of it.
Yes, some people's legacies are complicated. For example, Watson. After all, though he was racist, don't forget his other traits. For example, he was also sexist. And also anti-semitic. And a data / idea thief. So let's not forget all the different facets.
November 8, 2025 at 1:45 AM
Watson had it all: misogyny, racism, anti-Semitism, homophobia. He would have been anti-trans if he’d heard of it.
Reposted by Roland Dunbrack 🏳️🌈
We enjoyed your visit to Univ Maryland Baltimore and great to spend time with a colleague with whom I shared an office 35 years ago! Ain't dead yet...
November 6, 2025 at 3:04 AM
We enjoyed your visit to Univ Maryland Baltimore and great to spend time with a colleague with whom I shared an office 35 years ago! Ain't dead yet...
Baltimore Penn Station is really beautiful.
November 5, 2025 at 10:42 PM
Baltimore Penn Station is really beautiful.
Reposted by Roland Dunbrack 🏳️🌈
I’m old enough to remember when Americans newspapers either didn’t believe that gay people exist or didn’t recognize our relationships or humanity (think of the early years of the aids epidemic). I’ve never fully trusted them since.
I feel one million years old here, but we do actually have a pretty reliable way of knowing what news is true. Did a real newspaper publish it? Then probably yes. Can’t find it in a real newspaper? Maybe not.
A large majority of U.S. adults now get news digitally, but nondigital news consumers are less likely to say they extremely often or often encounter inaccurate news.
Read more on Americans’ views of information accuracy and distinguishing truth from fiction:
Read more on Americans’ views of information accuracy and distinguishing truth from fiction:
November 3, 2025 at 4:49 PM
I’m old enough to remember when Americans newspapers either didn’t believe that gay people exist or didn’t recognize our relationships or humanity (think of the early years of the aids epidemic). I’ve never fully trusted them since.
Reposted by Roland Dunbrack 🏳️🌈
You laugh, but this is how the exododus went extinct
November 3, 2025 at 3:36 PM
You laugh, but this is how the exododus went extinct
Reposted by Roland Dunbrack 🏳️🌈
Congratulations, Andrew Cuomo!
I know how hard you worked for this.
I know how hard you worked for this.
![Red Trump-style graphic with images of Donald Trump and Andrew Cuomo.
At the top it says, "I'm going to pick [Cuomo]." - Donald Trump, 60 Minutes Interview, 11-2-25
Then beneath it
TRUMP ENDORSES CUOMO](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:j5hrotody26iqi24hcusufxu/bafkreib7wnor7hl45ryvmifde4sov74rrnexa3iecbyu7zxjx6brrslsiy@jpeg)
November 3, 2025 at 4:30 AM
Congratulations, Andrew Cuomo!
I know how hard you worked for this.
I know how hard you worked for this.
Reposted by Roland Dunbrack 🏳️🌈
Sad day for the folks who staked their reputations on lab leak conspiracy theories.
www.telegraph.co.uk/global-healt...
www.telegraph.co.uk/global-healt...
October 31, 2025 at 3:51 PM
Sad day for the folks who staked their reputations on lab leak conspiracy theories.
www.telegraph.co.uk/global-healt...
www.telegraph.co.uk/global-healt...
Reposted by Roland Dunbrack 🏳️🌈
You will not find a sadder post on the internet today.
October 30, 2025 at 8:10 PM
You will not find a sadder post on the internet today.
Univ. of Utah & Huntsman Cancer Institute are seeking tenure-track faculty in cancer biology (broadly defined), especially in combining experimental & computational structural approaches (incl. AlphaFold & other AI/LLM tools) to study cancer-relevant signaling.
utah.peopleadmin.com/postings/189...
utah.peopleadmin.com/postings/189...
Assistant, Associate to Professor DOQ
utah.peopleadmin.com
October 28, 2025 at 7:56 AM
Univ. of Utah & Huntsman Cancer Institute are seeking tenure-track faculty in cancer biology (broadly defined), especially in combining experimental & computational structural approaches (incl. AlphaFold & other AI/LLM tools) to study cancer-relevant signaling.
utah.peopleadmin.com/postings/189...
utah.peopleadmin.com/postings/189...
Moriwaki et al. used our ipSAE metric (github.com/DunbrackLab/IPSAE) and ipTM to evaluate predicted structures of protein complexes in biosynthetic gene clusters.
They "found that ipSAE showed greater discriminative power than ipTM in identifying true binding pairs among highly similar proteins."
They "found that ipSAE showed greater discriminative power than ipTM in identifying true binding pairs among highly similar proteins."
Our new preprint is out. Our group performed a comprehensive protein–protein complex prediction within 2,437 biosynthetic gene clusters. We predicted a total of 487,828 complexes for known BGCs, identifying 15,438 heteromeric interactions with an ipTM ≥ 0.6. (2/3)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Predicting protein complexes in biosynthetic gene clusters
Biosynthetic gene clusters (BGCs) are contiguous genomic regions that encode diverse, non-homologous proteins required for the production of specific natural products. Their genetic diversity underlie...
www.biorxiv.org
October 28, 2025 at 7:47 AM
Moriwaki et al. used our ipSAE metric (github.com/DunbrackLab/IPSAE) and ipTM to evaluate predicted structures of protein complexes in biosynthetic gene clusters.
They "found that ipSAE showed greater discriminative power than ipTM in identifying true binding pairs among highly similar proteins."
They "found that ipSAE showed greater discriminative power than ipTM in identifying true binding pairs among highly similar proteins."
It’s weird that British Airways does not know how to conjugate Middle English verbs: “May we haveth your attention?”
October 24, 2025 at 12:40 PM
It’s weird that British Airways does not know how to conjugate Middle English verbs: “May we haveth your attention?”
@us.theguardian.com headline: millions marched today. @nytimes.com headline: why they can’t be bothered to count crowds. Earlier their article said “1000s marched…”. They’ve changed it to “large numbers.”
I read the Guardian first every day. Then check the Times until it pisses me off too much.
I read the Guardian first every day. Then check the Times until it pisses me off too much.
October 18, 2025 at 7:55 PM
@us.theguardian.com headline: millions marched today. @nytimes.com headline: why they can’t be bothered to count crowds. Earlier their article said “1000s marched…”. They’ve changed it to “large numbers.”
I read the Guardian first every day. Then check the Times until it pisses me off too much.
I read the Guardian first every day. Then check the Times until it pisses me off too much.
Reposted by Roland Dunbrack 🏳️🌈
More from the LARGE "No Kings" rally here in #Philadelphia. #Philly has a history of telling kings to fuck off! #NoKings #StrongerTogether #PowerToThePeople #GoBirds #NoKingsDay
October 18, 2025 at 6:17 PM
More from the LARGE "No Kings" rally here in #Philadelphia. #Philly has a history of telling kings to fuck off! #NoKings #StrongerTogether #PowerToThePeople #GoBirds #NoKingsDay
Listen to this. 🏳️⚧️🏳️🌈
3. Zohran Mamdani, a New York City mayoral candidate, released a two-minute advertisement steeped in transgender history and direct commitments to the community. The ad was set to a SOPHIE song, the legendary late transgender artist.
Watch it here:
Watch it here:
October 13, 2025 at 4:32 PM
Listen to this. 🏳️⚧️🏳️🌈
Reposted by Roland Dunbrack 🏳️🌈
Sunday reading:
I wrote about the aggrieved extremist who is currently firing thousands of federal workers and ravaging state capacity based on conspiratorial nonsense - and about mainstream media’s infuriating tendency to sanitize Russell Vought and the regime he serves.
This week’s piece:
I wrote about the aggrieved extremist who is currently firing thousands of federal workers and ravaging state capacity based on conspiratorial nonsense - and about mainstream media’s infuriating tendency to sanitize Russell Vought and the regime he serves.
This week’s piece:
We need to talk about Russell Vought – But Properly
Why certain mainstream outlets insist on sanitizing Vought as a devout “small government” conservative – and what actually animates his war against pluralistic democracy
steady.page
October 12, 2025 at 1:08 PM
Sunday reading:
I wrote about the aggrieved extremist who is currently firing thousands of federal workers and ravaging state capacity based on conspiratorial nonsense - and about mainstream media’s infuriating tendency to sanitize Russell Vought and the regime he serves.
This week’s piece:
I wrote about the aggrieved extremist who is currently firing thousands of federal workers and ravaging state capacity based on conspiratorial nonsense - and about mainstream media’s infuriating tendency to sanitize Russell Vought and the regime he serves.
This week’s piece:
Very Philly.
Philly’s Scrapple Sculpting Contest was won by a Delco tattooer who carved the Tush Push www.inquirer.com/columnists/s...
Philly’s Scrapple Sculpting Contest was won by a Delco tattooer who carved the Tush Push www.inquirer.com/columnists/s...
Philly’s Scrapple Sculpting Contest was won by a Delco tattooer who carved the Tush Push
Philadelphia Art Museum director and CEO Sasha Suda, who judged the competition, said the winning sculpture pushed scrapple "to its absolute limits."
www.inquirer.com
October 12, 2025 at 12:25 AM
Very Philly.
Philly’s Scrapple Sculpting Contest was won by a Delco tattooer who carved the Tush Push www.inquirer.com/columnists/s...
Philly’s Scrapple Sculpting Contest was won by a Delco tattooer who carved the Tush Push www.inquirer.com/columnists/s...
He’s never deserved it. But also this has never occurred to me.
Who among us hasn't stumped scalding mashed potatoes on our spouse's head?
October 11, 2025 at 11:08 PM
He’s never deserved it. But also this has never occurred to me.