#Geroscience
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jpsenescence.bsky.social
I'm delighted to share our curated list of 100 open problems in ageing science.

This represents a collective, systematic effort to map the key challenges and knowledge gaps across biogerontology and offers a roadmap to guide future progress in geroscience.

link.springer.com/article/10.1...
Open problems in ageing science: a roadmap for biogerontology - GeroScience
The field of ageing science has gone through remarkable progress in recent decades, yet many fundamental questions remain unanswered or unexplored. Here we present a curated list of 100 open problems ...
link.springer.com
November 9, 2025 at 11:46 PM
americanaging.bsky.social
Applications open soon!

Apply for AGE’s Early Career Scholar’s Program — designed to support underrepresented minorities in aging research.

📅 Deadline: Dec 10, 2025
🔗 age.memberclicks.net
#AgingResearch #DiversityInScience #Geroscience #AGE2025 #CareerInScience
November 2, 2025 at 6:56 PM
medicine.stitches.today
Geroscience therapies like caloric restriction and senolytics show potential for extending lifespan and enhancing health in aging populations.

by Kritchevsky SB and Cummings SR in JAMA #MedSky

👉 get more here

📖 read the article: https://jamanetwork.com/journals/jama/article-abstract/2837435
October 2, 2025 at 4:35 PM
jama.com
📈 As the US population ages, the incidence of #stroke, #heartfailure, #dementia, and other age-related health issues is expected to increase.

Learn more about geroscience interventions designed to slow #aging and improve health outcomes in this Review.

ja.ma/4mPqoKB
A JAMA article titled "Geroscience: A Translational Review," published August 7, 2025, discusses geroscience as therapies to prevent age-related diseases like stroke and cancer. Experiments suggest interventions can delay aging, but human benefits are unclear.
September 23, 2025 at 4:20 PM
michaelringel.bsky.social
As an American Federation for Aging Research (AFAR) board member, I want to wish you a very happy and healthy new year. We are excited to see what lies ahead in geroscience and aging research, and we appreciate your support. Thank you for considering a year-end gift to AFAR: www.afar.org/donate
December 30, 2024 at 7:29 PM
americanaging.bsky.social
Congratulations to Jessica Halle, AGE 2025 Early Career Scholar Award 🌟 These exceptional individuals are shaping the future, let's celebrate their hard work and dedication to advancing aging research! www.americanagingassociation.org/age-2025-ear... #geroscience #AGE2025 #aging
February 13, 2025 at 9:08 PM
jacksonlab.bsky.social
New in GeroScience, "A machine learning approach for quantifying age-related histological changes in the mouse kidney" with Susan Sheehan, Seamus Mawe, Mandy Chen,
Ron Korstanje & J Matthew Mahoney 🧪🤝🖥️ 🧬 #machinelearning #ArtificialIntelligence:
link.springer.com/article/10.1...
A machine learning approach for quantifying age-related histological changes in the mouse kidney - G...
The ability to quantify aging-related changes in histological samples is important, as it allows for evaluation of interventions intended to effect health span. We used a machine learning architecture...
link.springer.com
January 11, 2024 at 7:48 PM
aging-us.bsky.social
Read this #blog summary about the #research paper, "Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity."

aging-us.org/2024/11/how-...

#aging #summary #longevity #ai #biomarkers #lifespan #healthspan #geroscience
How AI and Longevity Biotechnology are Revolutionizing Healthcare for Healthier, Longer Lives - Aging (Aging-US) Research
Aging research has made significant progress in recent years by combining disciplines like biology, technology, and medicine to tackle the challenges of extending healthspans and reducing age-related ...
aging-us.org
March 18, 2025 at 10:33 AM
karvjorm.bsky.social
Syötkö jo? Pähkinät voivat auttaa ehkäisemään dementiaa

Kourallinen pähkinöitä päivässä voi pienentää dementiariskiä, kertoo Geroscience-lehdessä syyskuussa julkaistu tutkimus. Tuloksista uutisoi Daily Mail -sivusto
www.mtvuutiset.fi/artikkeli/sy...
Syötkö jo? Pähkinät voivat auttaa ehkäisemään dementiaa
Kourallinen pähkinöitä päivässä tekee terää terveydelle, tutkijat kertovat.
www.mtvuutiset.fi
December 14, 2024 at 12:32 PM
jamainternalmed.com
From @jama.com:

📈 As the US population ages, the incidence of #stroke, #heartfailure, #dementia, and other age-related health issues is expected to increase.

➡️ Learn more about geroscience interventions designed to slow #aging#agingmprove health outcomes in this Review. ja.ma/3UQ85ZW
Box View
August 7, 2025 at 4:00 PM
jayroshe.bsky.social
"Aging-related diseases are chronic and long-lasting, so it is best to delay their incidence rather than intervene when they occur. This is why there is so much excitement about the emerging field of geroscience and its recent advances illuminating the biological pathways of aging." Andrew J Scott
The Healthspan Economy
A five-year-old today has an extremely good chance of living to 90 and beyond. To cope, we need an economic and cultural revolution aimed at changing how we age
www.scientificamerican.com
May 3, 2025 at 11:59 AM
americanaging.bsky.social
Meet Dr. Yu-Hua Tseng
Her cutting-edge work on lipid metabolism & aging is reshaping how we treat diabetes & metabolic decline.
🗓️ May 12 | 🕥 10:30 AM | 📍 AnchorAGE, AK
🔗 bit.ly/4cJx8Gd
#Geroscience #HealthyAging #LipidMetabolism #AGEAnnualMeeting2025 #DiabetesResearch #LongevityScience
April 24, 2025 at 4:50 PM
geriscidoc.bsky.social
"Repurposed for Aging": Which drugs have the strongest evidence as potential gerotherapeutics? Great discussion of metformin, SLGT2i, and GLP-1RA at #GSA24 by this #endocrinology & #geriatrics #geroscience Dream Team of Dr. Sara Espinoza, Dr. Carolina Solis-Herrera, Dr. Sandra Aleksic, and me.
November 14, 2024 at 12:44 AM
aging-us.bsky.social
In the Season 3 #premiere of the Longevity & Aging Series, Dr. Yu-Xuan Lyu joins host Dr. Evgeniy Galimov to discuss "Longevity biotechnology: bridging AI, biomarkers, geroscience, and clinical applications for healthy longevity.”

Watch ⬇️
www.aging-us.com/interviews/l...

#aging #series #longevity
February 25, 2025 at 3:55 PM
danielemagistro.bsky.social
Thrilled to share our latest research, great work of our PhD candidate Catarina Ramos at @NTUSportScience & SHAPE Research Group!🎉

🔗 Read it in GeroScience: doi.org/10.1007/s113...

Our study shows that physical activity (PA) influences gut microbiota composition in older adults (65–85).
Assessing the gut microbiota composition in older adults: connections to physical activity and healthy ageing - GeroScience
The composition and functionality of the gut microbiota (GM) changes throughout the life course. As we move into older age, it starts to shift towards a less healthy one, which may lead to an imbalanc...
doi.org
March 17, 2025 at 4:49 PM
healthspanmed.bsky.social
🛠️ Practical Considerations

• Monitoring: Like Metformin or Acarbose, SGLT2 inhibitors might require checking blood glucose to avoid hypoglycemia.

• Repurposing: As with Rapamycin, there’s growing interest in using SGLT2 inhibitors in geroscience trials to extend healthspan in healthy individuals.
March 29, 2025 at 12:00 AM
juliobasulto.bsky.social
"Este metaanálisis aporta pruebas robustas de que el elevado consumo de carnes rojas y procesadas aumenta significativamente el riesgo de cáncer colorrectal".
pubmed.gov/40210826
Ungvari Z et al. Geroscience. 2025 Apr 10. Epub ahead of print.
#MásVegetalesMenosAnimales
Association between red and processed meat consumption and colorectal cancer risk: a comprehensive meta-analysis of prospective studies - PubMed
Increasing evidence suggests that red and processed meat consumption may elevate the risk of colorectal cancer (CRC), yet the magnitude and consistency of this association remain debated. This meta-an...
pubmed.gov
April 12, 2025 at 7:34 PM
ewingt-phd.bsky.social
#Geroscience can't agree what #aging is

www.nature.com/articles/d41...

Even more problematic:

Each geroscientist is convinced that they themselves know what aging is

What do you think aging is?
— Loss of function?
— Accumulated damage?
— A disease?
— A continuation of development?
What is ageing? Even the field’s researchers can’t agree
Survey of scientists who study ageing finds no consensus on the fundamentals.
www.nature.com
December 4, 2024 at 2:21 AM
longevitytech.bsky.social
Dominika Wilczok on the global milestone making Healthy Longevity Medicine part of every medical student’s training.

longevity.technology/news/longevi...

#longevity #medicaleducation #healthspan #geroscience #innovation #healthylongevity #futureofmedicine
October 31, 2025 at 8:28 PM
biorxiv-physio.bsky.social
The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience https://www.biorxiv.org/content/10.1101/2023.10.08.561459v1
The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience https://www.biorxiv.org/content/10.1101/2023.10.08.561459v1
Although lifespan extension remains the gold standard for assessing interventions hypothesized to im
www.biorxiv.org
October 10, 2023 at 8:04 PM
agingdoc.bsky.social
Thanks! Thought I'd bring a little love ❤️from twitter.com/agingdoc1?la...

A more consistently academic following here so far👌, with potential collaboration towards supporting geroscience, catalyzing biomedical innovation, and driving forward global healthy longevity.

www.linkedin.com/in/agingdoc 👨‍🔬
twitter.com
November 20, 2024 at 4:25 PM
dogagingproject.bsky.social
We are thrilled to announce a new publication regarding the data collection infrastructure developed for the precision cohort. Check it out here: link.springer.com/article/10.1...

#geroscience #canine #longevity
March 6, 2025 at 10:23 PM
mattsnylander.bsky.social
Good sleep is important.
GeroScience., Abstract, : link.springer.com/article/10.1...
Insomnia accelerates the epigenetic clocks in older adults - GeroScience
Insomnia is a common sleep disorder characterized mainly by poor sleep quality and insufficient sleep duration. It affects a significant proportion of the global population and is correlated with phys...
link.springer.com
March 22, 2025 at 7:19 PM
americanaging.bsky.social
📣 Meet Dr. Noah Snyder-Mackler, expert in how social & environmental factors shape molecular aging. Don’t miss his talk at #AGEAnnualMeeting2025: “Environmental Modifiers of Molecular Aging.” 🗓️ May 12 | 🕝 8:30 AM | 📍 AnchorAGE, AK
🔗 Register: bit.ly/4cJx8Gd

#Geroscience #HealthyAging #Epigenetics
📣 Meet Our Speaker: Dr. Noah Snyder-Mackler Get ready to be inspired at the AGE Annual Meeting 2025 by Dr. Noah Snyder-Mackler, Associate Professor in the School of Life Sciences at Arizona State University and Core Faculty in the Center for Evolution and Medicine. Dr. Snyder-Mackler’s pioneering research bridges evolutionary biology, social behavior, and molecular medicine, focusing on how environmental and social factors—like social status, stress, early-life adversity, and natural disasters—influence gene expression, immune aging, and overall health trajectories. Through in-depth studies of nonhuman primates and large-scale longitudinal research, he uncovers how our lived experiences are biologically embedded, impacting how we age and our risk for disease. His work is featured in leading journals such as Nature Communications, PNAS, and eLife, and continues to shape the future of aging and environmental health research. 📍 Don’t miss his session, “Environmental Modifiers of Molecular Aging Within and Across Individuals,” during our Primate and Translation track. Gain critical insights into how non-genetic factors drive molecular aging and longevity potential. 🗓️ Date: May 12, 2025 🕝 Time: 8:30 AM - 8:50 AM 📍 Location: Tikahtnu Ballroom, Dena’ina Civic and Convention Center, AnchorAGE, Alaska 🔗 Registration is open—join leading voices in aging research and secure your spot today: https://bit.ly/4cJx8Gd #AGEAnnualMeeting2025 #MeetOurSpeakers #NoahSnyderMackler #AgingResearch #EnvironmentalHealth #MolecularAging #Epigenetics #Geroscience #HealthyAging #PrimateScience #LongevityScience #ASU #EvolutionaryMedicine #ScientificLeadership #AnchorAGEAlaska
April 23, 2025 at 2:13 PM
oknathanshock.bsky.social
Thank you to everyone who attended the 2025 Geroscience Symposium! See you next year! 🧠
April 10, 2025 at 3:12 PM