The Brazilian director Kleber Mendonça Filho conjures fateful interconnections among vivid characters living in the grip of military dictatorship.

Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.

James Watson, the co-discoverer of the structure of DNA who died Thursday at 97, was a scientific legend and a pariah among his peers.

Microglia influence amyloid-β effects on astrocyte reactivity in the living brain of individuals with Alzheimer’s disease. This phenomenon further contributes to cognitive impairment via tau phosphory...

Allergies can persist even in the absence of allergen exposure. Miranda-Waldetario et al. find that IgE-producing plasma cells mature, acquire survival adaptations, and persist for extended periods of...

The de novo purine synthesis pathway is fundamental for nucleotide production, yet the role of mitochondrial metabolism in modulating this process rem…

This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…

Food-specific immunoglobulin E (IgE) triggers life-threatening anaphylaxis; however, for unclear reasons, some people with food-specific IgE are asymptomatic upon allergen consumption. We studied stra...

Nature - Untreated fevers during pregnancy can cause more harm than taking paracetamol will, scientists say.

Science isn’t really moving towards equity; institutions are just perfecting the appearance of equity. We need to build an alternative system.

Nature Reviews Endocrinology, Published online: 21 August 2025; doi:10.1038/s41574-025-01164-2Immediate attention is paramount for addressing the escalating prevalence of severe insulin resistance during pregnancy. A collaborative and multidisciplinary approach involving clinical care, public health initiatives and advanced technologies is essential for enhancing care, improving maternal and fetal outcomes, and mitigating long-term metabolic risks.

Nature Metabolism, Published online: 04 August 2025; doi:10.1038/s42255-025-01337-3John et al. show that upon classical activation, macrophages undergo nitric oxide-driven reprogramming of nucleotide metabolism, which affects immune functions and responses.

Nature Reviews Neurology, Published online: 29 July 2025; doi:10.1038/s41582-025-01125-3Low-income and middle-income countries bear a high burden from dementia that is not reflected in research. This Review outlines the reasons for this disparity and explores the challenges and opportunities of dementia research in low-income and middle-income countries.

Lawmakers attempting to regulate children’s access to social media must decide whether bans or warning labels are the optimal route for keeping kids safe.

Data from nine European and North American countries reveal that the disparity in earnings between immigrants and natives is largely a result of segregation of immigrant workers into lower-paying jobs.

Nardone et al. elucidate the mechanism of the midnolin-proteasome pathway, showing how midnolin achieves nuclear substrate selection and how established proteasomal components are repurposed to enable a unique form of ubiquitination-independent proteolysis. This study also unveils midnolin downregulation as a key driver of multiple myeloma through the aberrant stabilization of IRF4.

Sex and gender research could lead to better, more equitable treatments — if it is allowed to continue without political interference.

Warming of +1.5 °C above pre-industrial levels is too high for the Greenland and Antarctic ice sheets, and even the current climate forcing of +1.2 °C is likely to lead to several meters of sea-level rise, meaning that only a return to +1 °C or lower will avoid extensive loss and damage to coastal populations, according to a synthesis of recent evidence.