Eric Topol
LightNews LightNews
banner
erictopol.bsky.social
Eric Topol
@erictopol.bsky.social
160K followers 310 following 3K posts

physician-scientist, author, editor

https://www.scripps.edu/faculty/topol/
Ground Truths https://erictopol.substack.com
SUPER AGERS https://www.simonandschuster.com/books/Super-Agers/Eric-Topol/9781668067666

Videos

Eric Jeffrey Topol is an American cardiologist, scientist, and author. He is the founder and director of the Scripps Research Translational Institute, a professor of Molecular Medicine and Executive Vice-President at Scripps Research Institute, and a senior consultant at the Division of Cardiovascular Diseases at Scripps Clinic in La Jolla, California. .. more

Medicine 88%
Public Health 4%
Posts Replies Media Videos
Pinned
erictopol.bsky.social
Eric Topol @erictopol.bsky.social · May 27
A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...

Reposted by Eric J. Topol

Reposted by Eric J. Topol

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 22h
no data or evidence for that (maybe worth testing in the future)

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 22h
I asked Kevin about VNS use in POTS, Long Covid, what may be considered an ideal use case
This is part of his reponse. Then there's the ear access.....

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 22h
1 minute of vagus nerve stimulation per day was recently FDA approved as a treatment for rheumatoid arthritis. A new Ground Truths podcast with Kevin J. Tracey who pioneered this field
erictopol.substack.com/p/vagus-nerv...
Vagus Nerve Stimulation and the Immune System
Kevin Tracey, the pioneering neurosurgeon who discovered the connection, talks about the recent FDA approval for rheumatoid arthritis and where this is headed
erictopol.substack.com

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 2d
"Our study highlights the presence of widespread neuroinflammation in the brain and increased levels of inflammatory cytokines in the plasma of individuals with post–COVID-19 active temporal lobe epilepsy.".
www.science.org/doi/10.1126/...
Neuroimmune activation in temporal lobe epilepsy patients with worsening seizure following the COVID-19 pandemic: A [18F]DPA-714 PET/MR study
TSPO PET and inflammatory markers reveal spread neuroinflammation in temporal lobe epilepsy with seizure worsening after COVID-19.
www.science.org

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 2d
What drives immunosenescence—the degradation of function our immune system with aging that increases the risk of age-related diseases?
Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging
science.org/doi/10.1126/...
B cells drive CD4 T cell immunosenescence and age-associated health decline
B cells promote CD4 T cell aging and decline in health-span parameters through intercellular communication and nutrient sensing.
science.org

Reposted by Joshua S. Weitz, Christina Ho, David Spurrett

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 3d
"We are bearing witness to what fear can do to the health of a community"
A poignant piece @NEJM about the Minneapolis devastation
"We care for our patients because they are human beings. Our patients are being harmed. People are dying unnecessarily."
www.nejm.org/doi/full/10....

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 3d
The largest randomized trial of medical A.I.
—Over 100,000 women in Sweden
—radiologist + AI vs 2 radiologists, in follow-up
—AI added led to 29% more cancer detected, 44% reduced workload, and
—Less cancer dx in subsequent 2 years, and, when found, less aggressive
thelancet.com/journals/lan...

Reposted by Eric J. Topol

erictopol.bsky.social
Eric Topol @erictopol.bsky.social · 3d
Discovery of an entirely new potential approach to atherosclerotic heart disease: targeted immunotherapy!
Studies in human coronary arteries to reduce plaque and the mouse experimental model. Another win for spatial multiomics @science.org
www.science.org/doi/10.1126/...
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Vascular smooth muscle cell (VSMC) diversification drives atherosclerotic coronary artery disease (CAD). Mechanisms governing these cell state transitions remain unclear. We applied multiomic single-c...
www.science.org