Eric Topol
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erictopol.bsky.social
Eric Topol
@erictopol.bsky.social

Eric Jeffrey Topol is an American cardiologist, scientist, and author. He is the founder and director of the Scripps Research Translational Institute, a professor of Molecular Medicine and Executive Vice-President at Scripps Research Institute, and a senior consultant at the Division of Cardiovascular Diseases at Scripps Clinic in La Jolla, California. .. more

Medicine 88%
Public Health 4%
Pinned
A new cover for SUPER AGERS after making the NYT bestseller list. Thanks to you for making it the #1 ranked new non-fiction book on Amazon.
amazon.com/gp/new-relea...

The US isn't Denmark when it comes to vaccines, written by a scientist from Denmark @annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...

Reposted by Karen O’Leary

The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system
www.nature.com/articles/s41...

Reposted by Eric J. Topol

Reposted by Eric J. Topol

no data or evidence for that (maybe worth testing in the future)

I asked Kevin about VNS use in POTS, Long Covid, what may be considered an ideal use case
This is part of his reponse. Then there's the ear access.....

1 minute of vagus nerve stimulation per day was recently FDA approved as a treatment for rheumatoid arthritis. A new Ground Truths podcast with Kevin J. Tracey who pioneered this field
erictopol.substack.com/p/vagus-nerv...
Vagus Nerve Stimulation and the Immune System
Kevin Tracey, the pioneering neurosurgeon who discovered the connection, talks about the recent FDA approval for rheumatoid arthritis and where this is headed
erictopol.substack.com

"Our study highlights the presence of widespread neuroinflammation in the brain and increased levels of inflammatory cytokines in the plasma of individuals with post–COVID-19 active temporal lobe epilepsy.".
www.science.org/doi/10.1126/...
Neuroimmune activation in temporal lobe epilepsy patients with worsening seizure following the COVID-19 pandemic: A [18F]DPA-714 PET/MR study
TSPO PET and inflammatory markers reveal spread neuroinflammation in temporal lobe epilepsy with seizure worsening after COVID-19.
www.science.org

What drives immunosenescence—the degradation of function our immune system with aging that increases the risk of age-related diseases?
Today's report: B cells are identified as the bad actors because they induce T cell (CD4) dysfunction and inflammaging
science.org/doi/10.1126/...
B cells drive CD4 T cell immunosenescence and age-associated health decline
B cells promote CD4 T cell aging and decline in health-span parameters through intercellular communication and nutrient sensing.
science.org

"We are bearing witness to what fear can do to the health of a community"
A poignant piece @NEJM about the Minneapolis devastation
"We care for our patients because they are human beings. Our patients are being harmed. People are dying unnecessarily."
www.nejm.org/doi/full/10....